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                    <text>April 23,

Mr. Ralph E. Box-mam
1313

Medical Pmtectiva

of Part

Wayne.

1363

Many

Indian

Miami 11mm Building
63%

North Grand Blvd.

St. Innis 3, Misamri
Dear Mr.

Burma:

Enclosed are three applications for the following scientists:
Dr. Tumn Itil, Dr. Sam Gamma. Br. Harry Neubauar
Mid you kindly pmvide
eavamga for each of than men for
$100,000!$300,080? An additional pmzaim for Dr. Neuhauer
smack nthemw.
is to be charged for

elem

‘

Thane man an: scientists at the Misawi Institute of
Psychiatry and the Psychiatric Reseamh medatim of Missowi.
During the time of tmir amplosnmt, would you please submit
tbs statammts. in duplicate. for thus: chm-gas to the Emcutiva
of the Psychiatric March Fomdatim of Missouri.
and than): you for your mommﬁm.

9mm

SW13:
Max

mm.

Exemtive

:4me
we.

yours,
M. D.

War

�</text>
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                    <text>May

T0:

23, 1969

Dr. Borenstein
Dr 0 Dongle!"

Dr.
Dr.
Dr.
Dr.
Dr.
Dr.

Itil

Longo

Hellerio
Nequet

Peepiglione

Titece

Enclosed is a copy of the report of the symposium
"Experimental and Clinical EEG" in Liege. Would you

please

make any

corrections or additions which you feel
relevant citations using the same

necessary, and add

style that I did?

corrections
directly to:
The

and

citations should be sent

Dr. G. Verdeeux

Centre paychietrique Saints—Anne
LGbOtBtOira d 'EoEoGo
1, rue Cebuaie
75

Paris lee

France

that it was a great pleasure to participate
I look forward to each of you visiting
in
when
next you are in New York, hopefully
my laboratory
the
International EEG meetings in San Diego.
immediately after
You

must know

these sessions and

my

best regards.
Sincerely yours,
Fink, 24.x).
Professor of Psychiatry

Mex

Mszp

�</text>
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                    <text>October 25,

19 83

Dr. 3. Born

Laboratory for Neuroendocrinology
University of Ulm

Steinhbvelstr. 9

7900 Ulm/Donau
Germany
Dear Dr. Born,
In the program of the September meeting of the German EEG Society, I
found a listing of your report, "Eifekte eines ACTH (4-9) Analogs auf die EEGAktivitﬂt". We have studied the effects of this compound in volunteers and
patients, without establishing a clear pharmaco-EEG profile. I would be grateful
for a preprint of your report, if the results have been positive.

Thank you for your cooperation.
Sincerely yours,

Max Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>Ely 8, 196‘

Dr. Ivan Burnt-k1
219216: State untvnrttty

Tallahasuoq, Florida

Boar Dt. Borofsky:

9! bay. tuctntly bean in can—unieution with Dr. Harold x. 81cc
rcsardins an appointment at this institute. ﬁt has tueomnuuded
that V! canzidct an applitttion from you for such : punitlan.
This institutt has In nutty. program in the analyttl of EEGbehaviortl rtlatians 1n Inn. ﬂu have set up a computer center
in assoctnttan with tbs EEG labcratory. At the prtsant ttmt we

are studying Eh: «tract. of drugs on both EEG and bchavior, with
both acute and chronic adminiattttton. Inithu coats: of thin
work II have bucoun exalted by the pocstbility of applying tack»
ntquct 11k; continuous pcrfatunnce tasksmnlsutcuonto and ruactton
tuna with concurttnt EEG nunsutaunnt.

It you fucl that this program is out thnt would intatett you. I
would apptteiata yaur discussing the Institute udth Dr. Rica,
who has had a ehgnea to read ant nunual ruport and to'discua: Our
program with us. I vauld be plcaaad to tucaivn a copy of your
curriculum Vitus for our causldaratioa.

statoraly yours,
Max

Itnk,

Dircctot

um»

H. D.

�</text>
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                    <text>mwmﬂ

April

A,

1979

Laura Bossi M.D. and
V.

Bettellochi,

L.E.R.S.
75013

Deer

Ph.D.

Paris, France

Drs.,

studies of new drugs and their classification
spread throughout the scientific literature. Many
reports bear the names of M. Fink, T. Itil, B. Seletu, J. Roubicek,
and M. Metecjek, among others. Some of the papers are cited in the
paper which I enclose. This represents the latest end most complete
summery 5f the methodology and its applications. For an earlier
set of papers, I suggeet you obtain a copy of "Psychotropic Drugs
and the Human EEG", edited by T. 1:11, 3. Kerger, 1974.

by

The

EEG

criteria are

If you are planning to undertake the assessment of
using quantitative EEG (camputerised EEG), I suggest that
.you visit one of the laboratories that ere using the method. The
techniques are distinctly different than conventional EEG, sleep EEG,
and averaged evoked potentials, and it is en edventage to see a
»

new compounds

system in operation.

Good

luck.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Mex

�</text>
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                    <text>April

3,

1967

Dr. Antonio Bottino

Assistant Director (Acting)
Aftercare Clinic
State of New York
Department of Mental Hygiene
39 East 17th Street
,

New

York,

New

York 10003

Dear Dr. Bottino:
Your

letter inquiring about referrals for medical

super-

vision for patients discharged from your clinic has been referred
to me. for reply. At the present time , negotiations regarding
this specific problem" are underway between representatives of the
Department of Mental Hygiene and this Department. Until those
negotiations are completed, it would be advisable that the present
arrangements remain unchanged.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF2kp

pt

�</text>
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                    <text>m 21,
m.

1963

mmumMm

Harlan].
Katmai.

Bank

Miler
of mm. Mt}:

691? Arlington Road

Miami

Bothasda.

Baum:

Mymhm,m.3ammhmhasjoiwdﬁmsuffofthislmtim.
Aspaztofhissmdypm,homsbeenintmtadinmaffamof

mmuhwﬂmlmmonhmnbehaviw.
mmmtw
libmrian a requast fcm ﬂame Wales.
ham received
Xerox
We

ofmoftmm,andﬁnémtmeyaminmuan,
the

I

copies

Jammmand Italim.

writing to inquim what faci li ties am available at
for grantees like Wu?

mution of such mm
am

The

PSC

far

articles are:

Giberti, F. Studio «311 cffutti newlogici a psioopathaigici di an
new fume and odaiem. Sistem Memo 11380.3, (1961) p. 167-175

mm,
M"

A.G.

Had.

Um,

H. and

we of

m metals in the Mt cf vanims diseases.

833? 3. (1962) 18.25

W

Em.

maturing

title

m
Imholdingtlnhmmpiaa ofﬁuomimandJaWarticlas

Psxdﬁma at

,

'1‘.

Subject:

aj

psychoses;

an (T0100). (1953.) ﬁg: 20%216

maximum.

whidalrnw.andwiumthosetoymwtoanyoﬂmtmmhﬁm

Wthntywmyindimte.

Mum.

Sincemly yams,

,

M

cc: Dr.

Pink,

Director-

J.

001:

H. D.

�</text>
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                    <text>Augmt 22, 1963

Dr.

lamina

mm

Bouthilet

Nation].

Bank
6917 Arlington Road

new. mar-yum

migraine:

Thebibmmmmmdmlmmmﬂtha
bit of luck, the penultimate will he done this “taxman.
little

Aasoonuﬂumfcmmmmmbmd,ﬂnjobofnﬂm
willbcdmnmdpmiupsmomhawthemla

WWW.
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Sachmhonneeds forhismi‘k.
Woman
ofmmnalatims?
«mummm
My

Mt mm.

Simily yam,
Fink,
m
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M. De

Cmyou

‘

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                    <text>ﬁngust so. 1963

Dr. Lorraine Boutlﬂlet

We

mm Dimmer

Nazism}.

for Mental Health
Natioml Instﬂmtc of Mmtal Health

Mmtion

Bethesda 1h, Hm'yhnd

Dnarlnwaim:
I hesitated sending captives to be translated until I heard
from: you, and apologize for the niaméeﬂteming. ‘Im of
the papers we mused. The third, Giberti, 1“. Studio
effetti mlogiai e psiaapathogici di un neuwo fmcodegli
ad
adzione 813mm NERVOSO Page. 3 (1961) p. 167—175; we have mt
been able to get a photocopy of this document in St. [01115. If
you owld mange to get it, Ir.
would be grateful.
Thmk you very men.

mm

.

Sincerely
Phi!
MPIew

em.

M.

Director

-

2

yam,
“0

Do

�</text>
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                    <text>Jun; 22,

1964

Dr. Lorraine Bouthilet
Nationtl clcaringhousc for
thtnl Bealth Information
Bethesda, unryland
Dan: Lorraine:

I was confused by your raccn: letter. and acknowledge herewith
yam: rtquant eh: uh. Bibliography of EEG in Hanna Psychopharnn~
eulogy be publtuhnd without your authnrshlp. I «a taking the
liberty. howavet. of adknowledging your great assistanca by the
£6110w1n33

\

”Th1: bibliogrcphy was ftrtt ptupared by the
Information Unit of the Psychopharmacology
Strvice Centar. ﬁctional Institute of Hints:
Honlth (now the National Claaringhouae for
Hintal Health Information). Dr. Lorraine Bouthilec
and Elsa Slain: Cromwell initiated the search...."

I Ital: thin
Hany thanks

qeknowlcdgmant

is satisfactofy.

for your couperution.
Stnecrely yours.
Max

rink,

Ditnctor

Htljb
cc: H11: Elainn Crown!!!

H.

n.

�</text>
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                    <text>June 26. 1964

Dr. Lorraino Bouthilet
National Clearinghouse for

Montnl.ﬂealth Information

Bethesda, Maryland
Door Lorraine:

I an anxious to gut information via Bio—science Informa~
:ion Exchange. Can you please give no the prosonc address,
ond I thidk, now noun? Ia thorn any tingle person to whom
I any direct inquiries?
Thank you very much.

Sincerely youro,
Ha: Fink,

Director
Mtljb

M. D.

�</text>
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                    <text>October 1, 1964

Dr. Lorraine Bouthilet
National Clearinghouse for Mental

Health Information
National Institute of Mental Health
National Institutes of Health
Bethesda, Maryland 20014

Dear Lorraine:
On my return from my holidays I found the announcement that
the Rational Clearinghouse for Mental Heatth Information provides
a new service. As you know, I have decided to go ahead with the
development of our awn information retrieval system and we are
developing a heuristic descriptor list.

I plan to be in Washington later on this month and should
like to take the opportunity to call you at that time and arrange,
if possible, to meet with you for a few minutes to discuss the
possibilities, if any, of collaboration.
'

The galley proofs of the EEG bibliography have been re~
turned in final form and I believe the volume is now in piess

and should be

available soon.

Sincerely yours,
Fink,
Director

Max

mf/ls

M.D.

�</text>
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                    <text>“October 28,

196‘}

lot-mine Bouthilet,‘ Ph.D.
(hief, National Closrdnghouse for
Mental Health Information
Habitual Institute of Marital Health
Bethesda, Maryland 2001!;

Dearlorminoﬁ

We

chasvoryplocsodtossshwmlltm
has
program

progressed.

Indeed. the state

ofyozmopomtimissudusstomdxmmtomassoss
our am Mme-[in this field, for as you low, it is an
cxpensiw owstim. If your center will be able to pro--

vids us with the informtim needed, it may no longer be
necessary for us to maintain cur own operation.
to

Howavcr. before making

should like

some

additional

out: a decision I

infomtim.

.

1. Would it be. possible for you to send us
a sample set of citation and abstract cards plus a guide
to any mmic notations on these cards? (I should like
to determine whether the fomat and informatim on the

cardsisoonpatiblewiﬁzmmovm,mdifthemissane
additionslinformtimthatyouamputtingmﬁxeoards

that

we

should consider for our cum).

2. In the event that we consider naintaining
our citation service hers, would the Clearinghouse be
able to provide the Hissoxmi Institute of Psychiatry with
duplicate citation cards and descriptors (? and abstmdﬁ)
so that the citatims omld be included in our disc files,
marshy greatly expmding this local service? ’Ihe
Institute would be willing to dofmy the costs, and would
you phase provide me. with an estimate for such a collab-

Sinoemly yom's,

mf/ls

Pink,
Dimctw{

Max

14.1).

'

�</text>
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              <elementText elementTextId="13442">
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                    <text>W
13m.

6,

1961;

lamina Bouthilet

Hadrian]. Institutes of Realm
Bethesdn, Maryland 2001“

marten-nine:

It mmmatpleaswutosmdyouecopyof

thebib

ywhidxhas finallybaenwbﬁshed.

Mstu'tedoutasssmllendemmnmmpmw.
mdw,mdsttims1hadthefeeﬁngmtitwm'
goingtoovenhelmm. {hammitlodcsgoomm

Ihapettutitismm.

'

We.
tommdlmxderwhatsmdmtsmymfmm
With

the development of tho

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to the smasful pmductim of such a bibﬁogxaphyl
not?

mywillhmitsoeasy,willthey

Wumm on m Willem: efforts.
Sincerely
Mam

mm,

Maw

mf/ls

57m,
M.D.

�</text>
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f

i]

July 6,

1965

Lamina Bouthilet, Ph.D.

Chief, Natioml Clamﬁngmse for
Mental Health Information
Rational Institute of Mental Health
Bethesda, Marylmd 2901“

Dear

Lomim:

for the printout of recent articles
a side affect of
payctnphmceutiaals. This is quite helpful and I have
asked my associate to mad
of the references which you
Thank you very much

concerned with chmgo

have suggested.

in

body weight as

m

Sinc‘emly ycmrs.

PM ’ n
m
meesuof‘ of Psychiatry
O

HPmp

DI

�</text>
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                    <text>.W

.
.
.

v
..

m

h

.

December 26th, 1972

_

,‘..

wﬁ“~,._7m.,,.

Mr. Kenneth Bova,
,.‘..,,,,mv_wv,r~w

_.

Facilities Planning affine,
Administration h39,
SUHY,

Stony Brook.

Dear Mr. Bova,

behalf of tho Department of ?syeh1atry and my
associate: at International Aasceiaﬁion for Paychiatric
Research, I want ta thank.you for your excellent
recommandatinns, bath as to danish and as ta the contractor,
and for your guidance in renovating the EEG and aomyuter
facilities in the depurtmant at Surge I. I hava been through
renovations before, and can recall no previous cccaoion when
the planning and renovations went so smoothly and so well.
On

Plague aceeyt the enelosed
My

gift

on our

behalf.

vary best wishes for a successful 1973.
Sincerely yours,

Fink, M.D.
Professor of Psychiatry
max

MF/id
Enc.

�</text>
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                    <text>March 1, 1983

Penelope Bowers, MD.
Boehringer lngelheim, Ltd.
90 East Ridge
P.O. Box 368

Ridgeﬁeld, CT 06877
Dear Penny,
Enclosed are draft copies of the report, "Pharmaco-EEG Analysis of
clonidine (Catapres): Comparison with l-Penbutolol (Betapressin)". The report
summarizes the experiences in the two studies of Catapres which we have
completed in normal male volunteers.

Catapres exhibits central effects at single doses of 0.075 mg which peak
at two hours after dosing and are no longer measurable at four hours. The EEG
pattern are those of a sedative or hypnotic, and are not consistent with the changes
seen with typical antipsychotic, antidepressant (thymoleptic), or anxiolytic
psychoactive substances. In these trials, Catapres elicited some lowering of
systolic and diastolic blood pressures and a slowing of the heart rate.
These findings suggest that Catapres elicits direct effects in the CNS, in
doses which may be clinically relevant.
A summary of the first study was presented at the ACNP session on
organized by Dr. Richard Resnick, and was published in
Psychooharmacology Bulletin (31:16-17, 1981). Do you think a more detailed report

Catapres

should be prepared for publication based on these findings

'?

Thank you for the opportunity to carry out these trials with this
interesting and useful medicinal. My best regards.
Sincerely yours,

Max Fink, MD.

Professor of Psychiatry
~

..

m-

;..
Mn":

mytno-ppxmmww.“marginaqwng

�</text>
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                    <text>November 22, l9 85
Penny Bowers, M.D.
Boehringer lngelheim, Ltd.
90 East Ridge
P.O. Box 368
Ridgefield, CT 06877
Dear Penny,
i received a gift of holiday wine with Kurt Hoffmann's card, and I
immediately thought, "Another year has gone by, and how is Penny?" It was kind to

- these bottles have been superior, and
special friends during the holiday season.

send the wine

I

usually share them with

As I wrote to Kurt, during the past year, I have put aside my work with
pharmaco-EEG and devoted most of my time to editing the new scientific journal,
CONVULSIVE THERAPY. I received the invitation to organize the journal in July,
1984 at the CINP meetings in Florence; agreed in September; and the first issue

was mailed in mid-April, I985. Succeeding numbers appeared in July and September
and the fourth will be mailed the first week in December. We are on a good
schedule now, and I think the journal has been accepted.
have enjoyed the work, and especially the challenge of working with
authors to improve their manuscripts. Some reports are hardly decipherable, and in
many, the English is horrid. From time to time, however, I regret not working with
volunteers and with the EEG graphs, but that work continues in the hands of others.
Turan has been busy with Hoffmann-La Roche, helping them with their problem
with Valium and generic diazepam. Twice, he invited me to his presentations in
Nutley,and I had to admit that his data are compelling —- there are differences in
time course of EEG effects for different formulations. To confirm his findings, I
wrote a protocol for them, and I am awaiting their approval.
I

trust the year has been a good one for you.
wishes for a healthy and a happy 1986.
I

My

thanks again, and my best

.

Sincerely yours,

Max Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>August 12 , 1963

Mrs. Ruth Boozer-s, Dept.

of Missouri
“varsitymascur‘i

Colmia,

W m. W:

Secy.
Arm: Dr. Weiss

Following are the mums and titles Of the people
who visited your Department with to. Bink on July
31, 1963:
Tumn
'

Itil,

M.D.,

Prinai

*

Scien at

Research
(BBB)

Sm}. Gemhon, 1M). , Principal Renew
Scientist

(Wlm)

Sol Garfield, M.D., Principal Research
Seinntist (Psychology)

Sincemly,

Mu‘k

(Mrs) Anita‘watzig
Segmtary to Dr. Fink

�</text>
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                  <elementText elementTextId="103692">
                    <text>November ‘17, 1972

Hr.

G.

Boyer

Division ﬂarcotic
.

mm:

&amp;

Brag Abuaa

500 Fishers Lane
Rockvillo, Haryllnd 20852

Door Mr. Boyor:

Enclosod is a formal BN9!) order mounting.
mthadyl for the continuation of our studica under

750 mg.

IND

levo-

6590 and 6825.

are also meiosing a copy of the protocol submitted as
sundown to our 181). The amount requested will permit the study
of 50 patients in a more definitive evaluation of levomthodyl and
We

an

methadone.
Wu

anticipate beginning this study about January
Sincerely yours ,
Max

Fink,

31.33.

Professor of Psychiatry

MI?

:13

ﬁne.

cc:

H. F. Dummy, 14.2).

_:_.

1.

�</text>
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                    <text>February 4, 1972
Gary Boyer

&gt;m‘o;r.w~

wqwr.w..—WV....&lt;

.,,.,m-W

Center for Studies of Narcotics
National Institute of Mental Health
5600 Fishers Lane
Rockville, Maryland
Dear Mr. Boyer,

“A”,

W.-

.,_,,.,.,.._

.—-.,

gmrﬂ—mw

As Dr. Durnbush explained, we have become most interested
in dissecting the different responses we have observed in chronic
hashish users in Greece in smoking hashish, U.S. marijuana, and THC.

availability of concentrated

The

an opportunity to

men.

~

dissect

some

THC-A-8,9, CBD, and

CBN

of the responses of these

may

provide

'tolerant'

v...»

weuvv—m-K'ﬂ'”

.nmw

Enclosed is the official BNDD order form, 222C for the
substances requested, for use in studies under contract HSM 42—70-98,

in Greece.

n."

it

We

will be visiting

expedites delivery,
Many

but,"

we

Dr. Petersen on Thursday, and
with you that morning.
meet
can

thanks.
Sincerely yours,

-

ru

-,»~yu—.~uw~

.

(Jenna-Ar»;

1'

r
~

Max

Fink, 24.0.

if

�</text>
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                    <text>June 13, 1972

Mr. Gary Boyer

Biomedical Section
Cancer for Studies of narcotic
and Drug Abun-

ﬂotional Institute of Mental Heolth
5600 Fiohoro Lona

Rockvillo, Maryland

Dear ﬁr. Boyer:
A~9, and

Our ongoing

v.3.

~ NINE

studios of cannabis ~ comparing hashiah THC~
marijuana in Greek chronic bookish unors re—

quires additional supplies of marijuana (35 grams. 2.6x

THC~A-9)

and IEC~A~9.

Pilot studies on these subjects for other constitunnts or:
in progress, ond so request additional amount: of THC—A—s, CBN, and
GED.

The appropriate Bab—2226

my

is enclonsd.

thanks .

Stncoruly yours,
Max

Pink,

211.1).

Prof-user of Psychiatry

Mrzig

Sac.

�</text>
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                    <text>August 24, 1972
Mr. Gary Boyer

Center for Studies of Narcotic &amp; Drug Abuse
National Institute of Mental Health

Rockville, Maryland
Dear Mr. Boyer,

Ref: Cyclazocine

August 5, we submitted the appropriate FDA 1571,1573,
from Sterling Winthrop, and supporting information
to obtain an IND for the study of cyclazocine at the New York Medical
College to Dr. Edward Tocus, Division of Neuropharmacology, FDA.
On

letters of release

Following a telephone

August 22, I submitted a protocol

you.

call to Dr.,Alan

Ramsay

on Tuesday,

for the study of cyclazncine to

In re—reading your letter of August 8, I believe the
delay in obtaining an IND may be occasioned by the fact that the
information was submitted to Dr. Tocus directly. Perhaps, an
intervention from your office may release the appropriate IND
designation.
Thank you.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>August

7 , 19 72

Mr. Gary Boyer

Biomedical Section
Center for Studies of Narcotic
and Drug Abuse

sational Institute of Mental Health
5600 Fishers Lane
nockville , Mary land

Dear Mr. Boyer:
To

provide parallel information in New York for our studies
we request the following addition-

of cannabis constituents in Athens,

al supplies:

CBD

CBN

(crystals)

5 mg/amp.
(SSC 69780)

24 amp.

10 mg/amp.
(SSC 61565)

12 amp.

Deltae9—THC

3 amp.

(SSC 69682)
1 gm/S ml/amp.

The
Many

appropriate

BED—222 C

form

is enclosed.

thanks .

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

MF:ig
Enc.

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                    <text>'i
"Irv-I'm“

-

August 24, 1972
Mr. Gary Boyer

Div. Narcotic

&amp;

Drug Abuse

National Institute of Mental Health
Rockville, Maryland
'

Dear Mr. Boyer,
mm

.,u

-

,w...,y..-;.A...A...v

,Vlwww

application for an IND for the
Hospital at Northport, in conjunction
study of cyclazocine at
NIMB
contract for the study of narcotic antagonists, negotiated
with the
NIMH
with Dr. Stanley Yolles of SUNY-Stony Brook. The application
by
for an IND, including the FD 1571 and 1573, letters of release from
to Dr.
Sterling Winthrop and supporting data were sent directly FDA.
of
the
Edward Tocus at the Division of Neuropharmacology
On

August 5, I submitted an

the V.A.

Tuesday, August 22, I Spoke to Dr. Alan Ramsay who
indicated that a special protocol for the study of cyclazocine was
secretary
necessary. To comply with that request, I called Dr. Yolles
and asked her to send the copy of the contract between NINE and the
University, which spells out the details of the study. That protocol
was sent to your office.
On

From your

letter,

the only

special request of waiver of the
obtain

it

secretary

30

.WW

we

day waiting

omitted was the

period..

Should it be useful to obtain the IND number before we
from the FDA, may I ask that your office call Dr. Tocus'
?

Thank you.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
mv—r-

1

detail

two installations, be
Brook
on September 1;
advised that I am assuming my position at Stony
Freedman
Professor
and have agreed to continue as Adjunct Professor with
Freedman
Dr.
As
soon as
for the remainder of the present academic year.

P.S.

To

clarify the fact that I

am

writing from

assigns administrative reaponsibility to another physician, I will notify
your office. Until then, I would be grateful if you would honor the
requests from both institutions over my signature.

�</text>
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                    <text>Fly...

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Jam

28 , 1973

Kttt, Ph.D.
011mm Renard!) Branch
National Institute of Manta Heath
neutrino. hrylnnd

Martin

Dear

Win,

melon“! are
m today.
I signed with Mr.
mum Ct Winston. and an editor“). which in m in mu in
tho Journal, Biological Psychiatry.

It

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carpi“ of the contact
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until

I trust

Manda 3"

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by now.

Sincerely yours .
Pink, NJ).
m
Professor cf Psychiatry

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                    <text>aw“

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                    <text>Mt? 91!. 19T3
Dr12mg

Ken‘b'

worm”:
Centaur,

Retinal

Salt Esta c1gggébunty Hamlin Dept.

1% East 611: south, 7‘
8:11.13ka @113, Utah 31111.
Eon: Boater aﬁﬁnnon,

‘if! @he gape: en ”Hareatie Antaganiats” requesﬁed

Ew'yeu will nab be avn11able un111 yubl1ahad by the
Eutiana1 Caun1in1en‘in the summer of 19?3. I suggest
yen vr1te to tEn cummias1on tar augmlqmanta, when
uwi?
.ainoerely yours,

Pink. M.D.
th
Prefosaor of Psychiatry
13/13

�</text>
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                    <text>August 23, 1972

Mr. Gary H. Boyer

Chief Pharmacist
Center for Studies of
and Drug Abuse

sarcotic

Fishers Lone
Rockvllle, Metylend 20852

5600

Deer Mr. Boyer:

Enclosed is a copy of our ongoing protocol for the clinicel
evaluation of cyclazocine 1n the treatment of opiate dependence.
In part, this protocol amplifies the contract, ﬁSM~AZ~72~207 between
ﬁlﬂn and Dr. Alfred Freedman of the New York Medical College.
You

will note that

we have an ongolng maintenance

and e new group being inducted
Thank you

for your help.
Sincerely yours.
Mex

Fink,

M.D.

Professor of Psychietry

Hing
cc: Alan

3133

Ramsey

papuletion;

to high dose cyclezocine (to

20 mg/dey).

�</text>
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                    <text>Oetdber 25th, 1972

Mr.

My

B§

30””.

Chief Pharmneict.

Prcclinical Drug Study Saetion
Centar for Studias of ﬂareotie

and Drug Lhasa.

Rational Inatitutc or mental Health,
5600

Fishers Lane,

Dear

Mb.

Boekville. Mhryland 20852.
Boyer;

Enclosod in a raqneat fur 190 gram: placebo marijuana
and adaitional supplies cf THO-dolta»?. and marijuanu (2.65

THG~aelta~9) .

I received a telephane @311 from Professor Coats:
Stcfnnia of thy Uhivgrsity of Athmnn vhn in undertaking acute
investigations at hashiah, marijuana and TKOadalta~9 in
chronic hashiuh usara. unﬁt: H.I¥M;H. contract #h2-70~98.
He requested sufficient supplies to complato an additional
31: subjects and I shipped theaa to him from the_supp11os at
thn Kev York Hadical College. The material requnsted with
this order is to replace the amount shipped him.
sincerely yours.

Fink, M.D.
Professor of Psychiatry

Mix

WI 1.)
Sue.

�</text>
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                    <text>7%3—539A

Ibbruary 16th, 1973

Witt.

Gary H. Boyer, Chic!
Program ﬁwport section,
Center for {Studies or

Maﬁa

B

Dang Aha-c,

ﬁational Institute of Mbntal Health,
5600

Fishers Lane,

Roakvills, ﬂhryland

20852.

mm.m,

the Northport V.A. Hospital we now have five
pattonts on daily eyelasocine. we foresee that the present
suypliea will be exhausted. in about two weeks, and estimata
that by the lat March we will be using 5 x 120 cc yer watt.
M:

I

"writing 1m request an bottles (120 cc
#242415.
eyeluoclne under contract
am

If pouibla, this

m

should be shipped

Ed).
m
m.
mayor-taunt. of

mh) or

dirwtly to:

thiatry,

Bulletins 63.
Veterans Administration Hospital,
Harthport. NJ. 11768.

Attagtiom

Mn . Hurray

sincerely yours.

ﬁn: ﬁnk. 3m.
Profuse: of Psychiatry

”/13

cc. to Alan Runny.

14.1).

�</text>
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                    <text>TEL-533
v

3':an 15m: , 1973

v

-

w-wr—

m-

-_
—.-:

wsgz'zrgwrvuﬂwrwv'“

3W

Canter for Stadium of

Kutiantl

“2133’"?!

911mm,

Gary B. Ban-r, Chief
Program
auction.

lunatic

a.

Drug Abuse.

Institm a! 1mm Health,

5500

”abort

Dem-

m. Boyer.

Lane.

Reaching. Maryland 20852.

rum.

'2mmnW

n

helmet! in 3.1 gram or huhhh whieh rcpt-«ant: a
at the tutorial and in the ongoing study of chronic:

Ethan:-

"KIWI

’is'nw‘

1”":

W1
‘

a

sample

habit};

mm

in Abbas.

The sample was brought back by
and we am sending
to you for

it
I
:30th
any.
would Wen“ your sanding thin totuuy and sending
and Fctmon.
to Drs.
copies of that
Dr. Dambmh

this we:

was: tho ten: of

"port

Thank you

for

my! Mao-.98.

8m

m coopmtian.

Simone-01y

yuan .

Mu Fink.

H.171.

momma 131mm:

mu

Ems.
em. to

Btmn ﬁlm.

24.13.

Robert Peta-sen.

241.13.

�</text>
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                    <text>February 2, 1973

Mr. Gary, :1. uoyer

Chief Pharmaciat'

Program Support

a

and Drug Abuse

National Institute of dental Health
5600 Fishers Lane
Rockville, Maryland 20852

_

~

Dear
_

.g:
.

section

Center_for Studies of Narcotic

‘
-

.

Jr. Boyer:

Enclosed is an oriéinal order form for 5 grams recrystal*
lized herein. we are continuing our studies of the narcotic antag—
onists, specifically naICrexone.

this

L'lail

1o avoid difficulties we would appreciate your shipping
by messenier to tne new York hedical Collegc or by negistered

t9;

E’iax

Fink,

24.1).

P.O. Box 269
Great Neck, New York llOZl

’he above address is a reliable address for the delivery

of such unusual items.
(

Sincerely,
ﬂax Fink, 2w).
Profassor of Psychiatry

�</text>
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-,-»

'V'v-sr- ~.-«mwm

a:

‘

wa—nu-rmv-mr'

“-1

tmt‘vtm'n’us; “1': w- wvmnmmmuwwwwwmv-rw

‘m'

,‘w. mm»

"pr: «gnaw-amp.“Why-“10‘.

,

~7..w:‘.~lrxr1r“ WIN-run"

Novembce 8, 1968

0e. Phizip

A.

Boyce,

Je.

Medical ainectae
Menéon Laboeatoniee, Inc.
10236 Bunkee Ridge Road

Kama Cay,

Meow 64137

Venn 0e. Boyce:

Thank you 60a yuan tattea 06 Novembea 4, concenning
pyaaualeaone. The bindieb we peopoeed éoe thee compound
weae deacueeedeuéth De. Pogge in 1965, jubt pecan to my
Leaving Micsouni. My ﬁizee contain the tezxeee to De. Pogge
and the paapoeed peatacoz, but not the phaemacatogical an
cliniceﬁ data which he eubmétted. That 5££e wee test en
Miaeauni.

Beger anbwening gone hind Lettea, I woutd appaeciate
05 the avaitabze phanmacozogicat and clinical mateaiai.

a copy

I £00k seaweed in déecueeing the pnopoccd peageam ea
coon ac I have had a chance to nead.the availabze data.
Sincecezy gauze,
Fink, M.v.
Pnoécéean 05 Paychiatey

Max

MF:kp

v

2mm

~:7-

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2

�</text>
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:—

c-y.

a

r »-...,:-.....,s.

..,x..._..,W~,.H,

January 22, l969
Dr. Philip A. Boyer, Jr.
Meoical Director
Marion Laboratories, Inc.
ioaau Bunker Ridge Road
Kansas tity, Hissoori 64l37

hear hr. boyer.

‘

Thank you very much for the reprints describing studies
of orugs in hyperkinetic children. I-did find the articles
interesting and have sent them to ”W associate, Dr. SimeOn.

subject of
is unclear.
A few years ago we die administer papaverine in single doses
and were able to show changes in the ttG at a tine when
peripheral blood pressure was altered. This study did not
provide enough data to assure us of the central effects of
papaverine. There have been nuncrous studies of the effect
effects of vasooilators
increasing interest, but one for
The

on EEG

is

a

which the oata

of carbon dioxioe on ttﬁ, but these were done primarily using
visual analysis and here too the data is unsatisfactory.

investigator, John Whittier, has been interested
effects with vasodilators but his techniques are
in the
and
his studies should be replicated.
limited
The substance of these remarks is to indicate that while
the demonstration of EEG effects of vasodilators is not complete,
I believe that vasooilators will effect the Etc and that
quantitative methods could describe the changes.
Again, aw thanks for the reprints.
one

EEG

Sincerely‘yours,

Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

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                    <text>1

1

A

.
_

‘

,w

WWW“

a.“

“ﬂaw“.-.ﬂ.

”......w. ., .

.._.~{.,,,.../_vmr..-.

"um. . .

..... V,._.7.,..,,,.,.... ....-.i

v .

V--wr-"fr7‘~“lmw|
x-

«w

s

,

January 15. 1969
.
my”

1

m‘prUfm-Vrlﬂrvmv-

Dr.

Philip

Boyer

iarion Laboratories. Inc.
P. 0. Box 963
Kansas

..

City. Missouri

64141

..._.

....Jﬁra‘

”aggrwm

”gum—n.”

Dear Dr. Boyer:

Enclosed is the revised protocol for the “EEG Identification
of Pyrovalerone (F 1983) Activity" as well as the FD 1572 and my

curriculum vitae.
Thank you

-

7
:vﬂv

for your interest.
Sincerely yours.

"ytfﬁwlﬂm'ﬂ‘wjr"

‘m

-

Max

v—I'T'rgw‘mr-

Wm.

"v

MF:kp

enc .

,.

-.

‘._-&lt;~

yaw;

_

r—«u—rm,

1v,»

-

r
m

u;

'IG'J‘;‘JI'-W_;'v,mn&gt;:-

.
,r

Fink. M.D.

Professor of Psychiatry

�</text>
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«v

m».— ~» '1"~"N-z-~

wo-‘mv-

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u‘vxmvy-‘n—nvmww mum:

mﬁll!wmrv'm‘wrwmwryrru"‘va-

April 11.
Dr. Philip A. Boyer,

...,.,v_...,,—

w

,

,

__.._.-.v....r.xc. ”an--.”

1969

Jr.

Medical Birector
Marion Laboratories. Inc.
10236 Bunker Ridge Road
Kansas City, Missouri 64137
Dear Dr. Boyer:
Thank you for your letter of April 8, inviting me to
you at the APA. I regret that I will not be attending
the APA meetings since I have a prior commitment outside the
country. I will be at the Society for Biological Psychiatry
meetings and will be pleased to meet with you on Saturday.
I will be at the Hilton Plaza Hotel.

visit

v.

.
V.

.
,

.

.,—.

a
A

.7.~.-...vv

We have begun our open EEG study this week and we hope to
have some data by the end of the month.

”nu—m.

Sincerely yours.

..

“.1,"

Fink, M.D.
Professor of Psychiatry

Max

,,,'.‘....

”4n

"rem.

..»

w
«

v
»

nuvw

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                    <text>April 10. 1969

Sr. Philip A. Boyer
Marion Laboratories

10236 Bunker Ridge Road

Kansas

City. Missouri

64137

Hear Dr. Boyer:

In checking the supply of pyrovalerone, I do not
find any ”placebo“ tablets. Even in the pilot study
it would be useful to have 20 placebo tablets each for

the

tablets of pyrovalerone.

40 and 20 mg

Thank you.
5

Sincerely yours.
Fink. M.D.
Professorcf Psychiatry

Max

MF:kp

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                    <text>April 7, 1969
Dr. Philip A. Boyer
Marion Laboratories
10236 Bunker R d
a
Kansas City. Misgguriag4137
Dear Dr. Boyer:
I have received the supplies of pyrovalerone and our
trials will begin this week.
As

illness.

initial

subjects will be volunteers without mental
following records are obtained for each subject:

you know. the
The

Summary

psychiatric evaluation. social data

Permit for investigational drug use
Clyde Mood Scale (before and at fixed intervals after drug)
NYMC symptom check list (usually changed for definitive
EEG

experiment)

summary, based on

visual

and

quantitative analyses

pilot study. these data do not necessarily follow a systematic
collection schema. since we are exploring the appropriate times and
dosages for the CNS effects. Nevertheless. the data is available. in
whole or in part. for submission to the FDA. It has been my custom
to invite the monitor to review the data before it is simply duplicated
During a

and shipped.

recent discussion with Dr. Jonathan Cole. now the
Superintendent of Boston State Hospital, he expressed an interest
in studies of vasodilators in the mentally ill aged. eSpecially
In a

wry-«m-

7.:
“n

those with organic mental syndromes. I recollect that you expressed
a similar interest. May I suggest you call Dr. Cole and discuss it
with him. if you are still interested.

i

I

_«

trust that

X

will

have some data within the next 8 weeks.

Sincerely yours.

pvt-«wavy:

an?"

&gt;

'42qu

--

Fink, M.D.
Professor of Psychiatry

Max

pr'ﬂﬁﬁ

MF:kp

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Dear Dr. Boyer,
no are in the midst of an evaluation of the initial
pyrovalerone data and it should be possible to review this on
Friday. May I ask that you join me at my office at 5 East 102
at 1:30 p.m. ?

I look forward to your

Street

visit.
Sincerely yours,

Max

Fink, M.D.

Professor of Psychiatry

mf/

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                    <text>.mwm

..

,.

:w-z

-

nm‘d"-’:‘,K‘.mmev:uu:v.~vamy ,- falan' “um

m—

wow‘

—

I.

m

"J‘ -.”maﬁa-urnzvavwr. (.73.... r
.

.

v...,r.,~-«..r_..

g,

7..

7,.

August 25, 1969
Dr. Philip A. Boyer,

Jr.

Motion Laboratories. Inc.
10236 Bunker Ridge Road
Kansas City, Missouri 64137
Dear Dr. Boyer:

is the ounnary of the pilot pyrovaleroue ~
EEG study in volunteers. The data is sufficiently clear
to answer the questions set for this study, 1.e., behavioral
and EEG affects aro readily apparent at 160 mg pyrovalerone
(single dose) in normal, adult volunteers; and that this dose
Enclosed

is safe

and

well tolerated.

I have sent a copy to Drs. Itil and Pfaiffer, as I had
promised in our initial discussions in Miami in December.
any

After reading this summary, would you call

additional data
my

you may

me

regarding

require for your records.

boat regards.
Sinceruly yours,
I'm Fink. 14.3).
Professor of Psychiatry

Hrakp

one.

“,3.

._v

v,“

A.

7...... ...

»...

.1...

r...

.

.3.“

5.

._WV_

�</text>
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                    <text>September 2, 1969
Dr. Philip A. Boyer,
Medical Director

Jr.

Marion Laboratories, Inc.
10236 Bunker Ridge Road
Kansas City, Missouri 6&amp;137

Dear Dr. Boyer:

I regret there was an error on page four of
the pilot study report on 8/22/69. Please replace
page four with the one enclosed.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>.

October 15, 1971

‘

wrmwn

Dr. Louis Bozzetti
Deputy Director, NCMDA
Washington, D.C.

‘2"

m".

art]

Dear Dr.

"WW-1;.“

.

Bozzetti,

I returned from Athens on October 6, and have been
catch
to
trying
up on my work since then. In Athens, I found that
the team had examined 31 chronic hashish users, and were preparing
to examine an additional 20. The data is most impressive, and we
are heartened that an intensive examination of these men will

be

significant.

We

have, therefore, proposed to

NIMH

to extend the

study, and I am now preparing the documentation they requested.

For this reason, I am not planning to return to Athens
end
the
of November, or mid-December.
until
At this time, there is little that can be served by a
would suggest you visit us in New York and I can bring you
up to date on the findings. If you wish to observe some of the
subjects during their examination, perhaps it would be advisable

visit. I

to wait until the detailed examinations are in progress.
Come

visit again.
Sincerely yours,
Max

Fink, M.D.

professor of Psychiatry

'
'-‘

‘.¥WF‘T€W,TW

"
"NW-

'9

Tyler-“rm;

C .3

�</text>
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                    <text>November 4, 1971

Dr. Louis Bozzetti
U.S. Commissioner Marijuana
801-19

Street

N.W.

&amp;

Narcotic Abuse

Washington, D.C. 20006
Dear Lou:
on the

It

was nice having you

visit

and

I

hope a

effects of chronic marijuana can be arranged.

presentation

Separately I have sent Dr. Henry Brill a proposal to undertake a study of chronic cannabis users in Jamaica, as well as a copy
of our Greek study interim report.

I am writing about another question. In working with
the Greeks, I was told about a prior study of hashish by Dr. M. G.
Stringaris, published in German. After much travail, I obtained a
copy of the original and asked a translator to make the text comprehensible in English. She has completed the first section (24
pages). I am enclosing a copy of her translation.
Is it within the Commissioner's activities to use such
a text and data, and can the Commissioner support the translation?
The text is 66 pages with an additional 33 pages of case histories.
My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:ig

inc.

�</text>
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                    <text>nur:

wv

.

.u

-vv-~

~

-"\ nee-Immmﬂ't": -w~»,v.—.‘a-w—»vw»vw~

.

-v-":'.-l-:::-Nv«~.

"Ku'rrvnw'rnvwrr-A‘n

._

w

v

(«a 1-,.» .

~W~

”vow/MN?

wu-

r-mwa: ,

April 5,
Louis P. Bozzetti, M.D.
Commission on Marijuana
Washington, D.C.

&amp;

v w

-&gt;

r

~-

-

'

.

-

.7

u

..

war

w-v

urn-w

-

n

1972

Drug Abuse

Dear Lou,

I have just read the report of the Commission, afetr
the
hearing
special program with Governor Shafer last week, and I
am writing to congratulate the Commission and you for the fine work
that you have done, in putting the marijuana issue in the perspective
that seems to me to be appropriate and necessary. I do agree that the
prominent unknowns are the long term effects, and hope that some of
the studies now underway may answer some of the questions.
appendices.
I

It is
As

know you

will
My

a

fine report,

and I look forward to the

I understand

it,

best regards

and congratulations to Jack as

your work

do as good a job on

is only partially done;

the other problems of drug abuse.

well.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

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                    <text>August 5, 1985
Dr. Bracegirdle
Keeper of the Wellcome Museum

Science Museum

Exhibition Road
London SW7 2DD
England
Dear Dr. Bracegirdle,

I hesitate to write the following, as it may appear presumptuous to
you,
but in a recent visit to the Wellcome Museum, I was struck by an apparent error in
the panel #T32. As I have recently written a history of convulsive therapy, and
published an autobiography of Ladislas Mcduna, I decided I would present my views
of the history.

The panel states that "In the 1930's, Manfred Sakel treated schiz0phrenia
by producing convulsions by injecting insulin. This in turn was replaced by . . ." The

treatment‘s origin was more likely in the work of Ladislas Meduna.

Manfred Sake! developed insulin coma therapy, and ardently maintained

that the induction of seizures, which occasionally occurred, was a complication to

be avoided. He presented his ideas in Vienna in January, 1933. In January, 1934 the
Hungarian neuropsychiatrht, Ladblas Meduna introduced camphor injections with
the intent of developing seizures, in the belief of a biological antagonism between
epilepsy and schimphrenia.
These two protagonists met at a meeting of the Swiss Psychiatric Society

in Mﬂnsingen in 1937. They differed in their views as to what was the essence of

-

each therapy
coma and the death of 'sick' brain cells in insulin therapy; and
seizures in Metrazol therapy. (In later years, Sakel emigrated to New York, and
asserted that seizures in insulin coma may have some beneficial effects.)

I enclose a copy of a historical review for your use. A more detailed
exposition of the Meduna story is to be found in the first two issues of the new
journal, CONVULSIVE THERAPY, in which Meduna's previously unpublished
autobiography is published. This biography was written about 1954. Other sources
can be found in citation 35 in the enclosed reprint.

I very much enjoyed my visit to the museum.

Sincerely yours,
Max Fink, M.D.

Professor of Psychiatry

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‘anl‘wkz‘uvl, m— V,v-v;

v-m"

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June 20, 1967

Dr.
J. Breoelmd, Editor
Marleen Jamaal of Peyohietry

-

1700

18131

W,

N. W.

Washington, D. C. 20009
Dear Dr. Bmoeland:

Emloeed

is

Canpu‘terAnalyeie

an additional copy of our report "Digital

ofthemmnﬁm inPsydxiatr-io Research "

Thispaper was presented at the recent meeting of the
Psychiatric Association in Detroit.
Thank

ya: for your consideration.
Simerely yotm ,
Pink, M.D.
Profeeeor of Psychiatry

Mme

Mszp

American

.

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                    <text>wand-"v '31:"!

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Dr. Mamie;

Editor

Micah

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57.1

Journal of Psychiatry

Dear Dr. Braceland:
Enclosed is a copy of the report "Digital Oanputer Analysis
of the Hum BEE in Psychiatric Research" which was mad at the
APA in Detrvit.

Ifthisdraftisaccetedforpublication,wewillbe

pig-236d
1)

ts.

to suhnit a copy

th citations

and

original glossy

Simerely yours,
Fink, M.D.
Professor of Psychiatry

Max

“rm“

._

J. Braeelmd

MP:kp

“nu

.

4.

.

W

van,

-v

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,

May

Mr. Harold Mehling,

Psychiatric Progress
3 West 57th Street

New

Deaer.

2

Mehling:

Enclosed is a preprint of our report to the annual
meeting of the Mariam Psychiatric Association, "Digital
Computer Analysis of EEG for Psychophamecology." It

wwldindeedbehelpfulifyoumuldcheckwithus before
of this material, for I believe we can provide

making use

you with additional figures, including glossy prints
which would make the presentation more satisfactory.
Therm you

for your interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Mm:
ryn—uw

m

Editor

York, New York 10019

ri'lﬂﬁwﬁmwr‘fm'15w)K,.131l'a",:rhmmf,lw.

.,

2, 1967

Mf‘ﬂcp

we.

:w‘ ”v.4” .vw.‘

�</text>
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                    <text>August 1, 1968
Dr. Francis J. Braceland, Editor
American Journal of Psychiatry

l700 Eighteenth St.. N.W.
Washington, 0.0. 20009
Dear Dr. Braceland:

Enclosed are draft copies of two reports summarizing
our experiences with a narcotic antagonist, cyclazocine.
Following theoretical models which have been of interest
for many years, we found that cyclazocine had a neurophysiological profile similar to imipramine. These clinical

trials, in two different populations,
does indeed have significant clinical

indicate that cyclazocine
antidepressant activity.

We are aware that such open clinical studies are
ordinarily of limited value since enthusiasm may effect the

treatment outcome in depressive populations. But the
demonstration of a significant application of available
neurophysiologic methods provides our incentive to present

this publically.
He

and ask

would appreciate your consideration for publication,
that the two reports be assessed together.

Thank you

for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
enc. (2)

�</text>
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                    <text>July 30,
Dr.

Maia J.

Editor

Braoclmd,

1700 Eighteenth

Washingtm, 0.0.

St. ,

1969

PM).

NW

20009

Wham:
Fwammberofyemlhavebemlaatuﬁngmcmvulsive
Mymdwtmlhadtheoooaaicntomakesuchapmsmtatim

State Hospital, Jamﬁm Cole mated that a manual
ofECI‘mightbauseful. Wiﬁxﬁlismammgmntwehmmpamd
ashort 8mm: "Oamlsive Ttmapy - Methods mdApplicatiaw".
at: Boston

Aoopyisanloaed.

Per-Inpaﬂxismaterialmayperfomaserviceasasupplenmt

or-spscialsaotimofﬁnmm

Jamaal. 06 PAycuauy.

Similar

domrrtshavebeenpmpamdbyoﬁmtmtmedisu'ibutimm
usuallybochlooalmd,withﬂ1erumdintomstinmilatwal
ECI',

mammaysmauscful purpose, particularlyin

psydmiatrictxuiningpmgum.
'man‘k you for your midmdm.

Stanly youm,
Max

Fink,

M.D.

Nasser of Paydliaty

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                    <text>"W“- .

m ~v,—

"—m—w

mr‘vzrw-‘vvwmw‘w

.

November 24, 1976

Francis J. Braceland, M.D.
Editor, American Journal of Psychiatry
1700 Eighteenth Street, N.W.

Washington, D.C.

20009

Ref: Paper

Dear Frank,
Ah, I wish

deletion

was

# 284

as easy as your note suggested

!

But, I have deleted slightly more than two pages; added a five line
reference to an important paper by Avery and Winoken; and removed
citations. I think the paper is improved, and hope your editors

ll

will agree.

I am pleased that you have decided to publish the papers
at the meeting, including Dr. Friedberg' s. I agree that there will
be some protest, but I think that it was important for the Association
to allow its critic to have the floor. After all, we have invited
Tom

Szasz on more than one occasion.
My

best regards.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

�an
us.-

~—.—.yy“v.w

1".-

June 9, 1976

Francis J. Braceland, M.D., Editor
9
or P‘ ohiat
a:i an J
1700 Eighteenth Street, H.W.
'

washington. DaC.

20009

‘

Dear Frank,

Enclosed are two draft copies of the report "Myths of Shock
Therapy! for your consideration for the Journgg. This report was
;
presented at the panel, "Electroconvulaivn Therapy: Current Perspectives",
at the May 1976 wasting of the ABA, and organised by Curl Salsman. You
should have received (or will roceiva) papora fiumthheobhhsr participants.
wn do hope that they will meet your standards, and that they may be
published together as a group of topical papers.
Thank you

for your consideration.

Sincerely yours,
Fink, M.D.
Professor of Paychiatry

M2:

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                    <text>July

30 ,

1965

Prof. P. Bradley

The Medical Seiwol

Bimianmn

England

15

Dear Dr. Bradley:

It is a pleasure to accept the invitation of the Program
Committee of the GIMP to participate in the plmning of a
symposium on Neurophemooloy. I lodt forward with keen
anticipation working with you‘ Following the Committee '8
suggestion, I am taking thin opporﬁmity to open our
diemzseims with the following tentative suggestions.

mating on the general subject of EEG md psychoplume-logy review ohms induced by psydzotmpic drugs in
psychotic subjects, whacking differences between schizophrenic
Varicmo

and depressive subjects and portraying drug specific pettems
1961); a general overview of EEG md behavior (Yale,
1953); nottodolow of oonputer techniqms‘ (Washington, 196%);
and drug effects in depmosive disorder-s (1965) . These
presentations were primarily focmsed on human observations .
In the recent Society of Biological Psychiatry meting mime).
and lumen EEG data were brought together on the special subject

(mm,

of "Nztioholimrgio Heliucinogens." Participants in this

sympoeimn included [no Abood, Richard White, Mam 11:11, and
w. P. Wilson. '11:: discussion and presentations were quite god
and beam of time limitations barely presented the raw material
of which “men was a omeidemble anomt. (If you wish, I om
send you draft copies of those muscripte.) As the subject
was of peat interest, perhaps a similar subject can be considered
in brain
for the CINP. The problem of cholimrgic
Emotion is of mtual interest, and such a subject would permit
dismeime of antidmlimrgic dmge including hellucinogens ,

Waco

mti-peﬂdmm agents ,

mohmiem in

amine and ooopolemine,ofoholinergic
various

201', and tho
psychotropic (Inge .

dxolimrgic aspects

A
one of focus is the peremxiel problem of the
dissociation of EEG and beluvior. Related to this subject is
the pmgmetic value of EEG. data for tho therapeutic efficacy
of peydwtropio (Mags; EEG dmngos in mimic as e pmdictim
of the effects in m; and in. men, the prediction of the general
effects of drug and the specific prediction in individual subjects.

�Prof. Bradley

July 30,

~2~

1965

of those suggestions provide a focus for us?
I am planning to attend the International EEG Metings in
View early in September. Peﬂmps we can meet in Imam to
discuss the program? My present plans are to leave Nan York
on Saturday, August 28, and I can be in London on Sunday aftemom,
August 29. Ifmoouldmgetomt,wocanspendafcwhm
planning the pmgm md this might be easier than an exchange of
Do any

letters.

the

As to other matters, I m enclosing a check for my (has
GIN? for 1-965 . Incichntally, scan mnths ago I received

for

the
galley proofs of one pmsentatim from the 19614 matings, but not
the other (EEG Patterns with Ocmbimd Drug Treatments in Psychotic

Patisnts; Drug Induced Dissolutim of Cortical Electrical Activity;
Imstigatims in Therapy Resistant Sdzizophmnic
Patimts) . May I ﬁnuim as to the status of these muscripts?
and

Wutic
I

loio'k

forward to working with you in this swims next
that we may be ablc to met in [snow mm: mm.

year, and hope
Hy

best mgaxdo .
Sincerely yours ,
Fink, Md).
Professor of Psychiatry
Max

2417'sz

cc: Dr. Brill
Dr. Cole

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                    <text>Hay

N.

Y. Bt

22, 196‘

It'd!”

Mm. m1 Organising Mn“
C! x. i. P.

11.. Radical Seine].

W

31mm...

15

D.“ 9!. Brad!”I

I would b. grants: 1! you 1mm and a provisional program
and an invitation to “and ﬂu mung. of the CJJJ. to:
of Poyehhuty
Mutant
ant. ”whey-thin mun

Mummy 9! Ian
2

mm bu plant!

in an inﬂux

to have

forward to

hi: «and

the mating:

main. with you at

ch.

u my mat.

ad a! Lawn.

”Manly you“,
Mu link.

Munro:

III/1!:
_

an:

9:. char!"

Mun

11.

b.

�</text>
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                    <text>Saptcmbcr 14, 1964

Dr. P. B. Bradley

The uoélcal sabool
Hospital Center

Birmingham 15. Englnnd

Dear Dr. Bradley:

ﬁlth to thank you for the vary fine arrangemnnto that ware made
Birmingham for the recent meeting: 6! the CIN?. While I misscd
many of our friends who failed to nutcnd the meeting, I found the
1

in

sessions quit; anjoy&amp;blc.

I am enclosing a copy of my summary remarks, and would ask if youv
would sené thcaa an to tha editor. The raportl of my associatas
are being :ditad and will be sent on as soon 3: they are prepared.
1

an sure you are enjoying a period of relaxation

task well dona.

after a hard

Sincerely yours,
M3: F1nk,‘K.D.

Director
MP/jb

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                    <text>October 23, 1965

Professor P. 3. Bradley
Inc radical School
Birminghm 15, Ehglmd
Dear-

Philip:

held

up answering your

inNummrgmdso
Ihadplmmdtobeatﬁwmtings
we could discuss
the

utter in

hope

that

this together. mfommately, I ma mable to make the trip at
the last mat andsomust send youthia letterwhim is apoor
substim for m Mute avian of this symposium.
First. I agmo thatwohava rams smug: fmmwhidmto
choose the invited participants. In wading your notes, I
know littls of Hofﬁmister, Kmiskott or Hen. I would adapt

of Her: but have little clad to go on. I
mnmtim
have and, my of the publicatiawfm Votava's mp md have.
fewyeam
mingmsudmtmyhmmminﬂmpast
than
be
om
might
and thcir mmtaticn
0min
mgarding Gianna. I have
in your matsm
speaker. I
W to speak to Hamid Hiawidl m momer matter
had the

your

wiry

and raised the quostim of whather he would be willing to
participate. He said he would Old while this does not imply
I believa that his experienm is extensive and
a
he is m activu partiuipmt in my dismsim. For this mason,
I mndsr we could not include both him and Imago, even thoug't

Mttmm,
if
both ham similar interests.

they

Tm

amnion

of

Ed Damim

is agreeabla.

I do not knad wheﬂnr Oatfeld has dam work recently, but
will call him if you think that we need an additioml clinical
mpmmtation and can then make a judgement after discmsing
this with him.

MIWMIwasmablotomtcNWrg,m,
enough to extwd

called Professor Page]. since he had ban kind
an

invitatim to both

Dr.

myself. As part of the
ItilheandWald
Washingtm
be coming

to
that he would. Since Beats is already preoccupied
with athar parts of tha prom, I believe that Professor Fl'égel
would b: the logical participant.
discussion I inquimd whether
and he said

�Professor Bradley

October 23, 1968

-2-

Before outing

to emcific mommdatims I would like to

addanadditiaulnamtothe list. While inVienneIhadtm
opportmity to Spend sum tin with Madam Vemaux who told me
ofﬂnetudieswhidmshehadmletedofatmpineandhitm

wanted electrodes in freely moving oats. She described
dissociatim between EEG and behavior in these animals,
the drugs had an effect on the electrical
indicating that
activity, the behavior of the animals were modified. Within the

with
no

m

Immm

last ten days, the latest issue of
Iowa 04
Remaphameelegy (Velma 4: 265a???) presents a report fm
her gmup. If the dismeeion is to few on this dissociation
problem, I believe we should add her name or om of her associates

list of invited

to the

participants.
In" any synposium of this kind, it is often difficult to
try to set the limits of the presentation for a participmte
I believe the title that you have sugwted is sufficiently
descriptive of the focus that we wwld like to eat. Rather
than moxibizxg the program in four sectime as you have
outlined peﬁmpe we should invite the speakers indicating the
foam much in the title. We om ask the invitees if they
wouldbewillingtopanieipatemdiftheywouldemdus a
few sentences describing their studies in this area. With the
letters in hand and our- knwledge of their past reports, we
could then group the studies according to their cmtent.
1. Attached is a list of names in three sections. I

believethefirstgmuparethoeeinwlmweboﬁmeonmm

,

The

seomd group are those who would provide the major bade-up.~
third gram am ﬁwee about wlm I have insufficient
information to make a mmdatim, but will abide by yaw

The

decision in

any

instmoe.

invitatim is no problem foe me, and
Iwillbepleasedtodosoifyouamabletoeinpljfyw
problem by prwidingmewiththeaddmw ofthosemthe
2.

list

To extend the

marked with

(Mesa 7).

3 . Having reviewed the literature carefully
few mmtlm I find that there is no adequate

dating the
sway of

past
the problem of mtidmlimrgies and behavior in animals and mm.
Porﬁxis reason, mdmeehavingtheexpense ofbringingso
investigators together, mm it not
my foreigz and Aux-idea the
be appmpmate to
publication of these proceedings
separate from the usual 6.1.533. volmne? The problem that
you have faced with the Bimingxam volmne has acute overtones

mm

foraylabmatowmdaslmsmﬁentehastoldyou,wem
all three publications from St. Innis
were found maeoeptable and that this information was not
to our intention mtil fully a year after the meeting.
sorely disappointed that

Wt

�Professor Bradley

October 23', 1965

~23»

If publication of a synpoeim report is a reasonable
suggestion, this should be indicated in the letter of invitation.
u.

If

many Emopem workers

participate in this symposim,

it wwld be important that translatims be made
available for as many session; as possible. Perhaps you mum
I believe

mﬂdswiahlummtommaminzmimowhenmdﬂm
C.I.N.P. executives
got

Hy

tower.

best mgards. am I

mt this letter finds you well.
Sincerely yams ,
Fink, 51.13.
Professor of Psychiatry

Max

HFﬂcp

mam
upmwmﬁmmmimmdmmhmm
hi
am
Vimmohu
Kano,
it
aim.
thth
ES.

Wamohwnﬁiohsmmidmlim

Ihyw'iom.

.

-w..,.

an

�</text>
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                    <text>W

As

9.

1965

of this 3111mm w. have mind positive replies
Carltm, Himiah. Itil. Iago. Votm and White.

fmm Dru.

erhasagmedmmbuthasmwmstﬁngmt
m. Vordemhualsoagmdtom
ifauppartcmbepmvided. Dr.
In".

finmaialpmblw.

some funds

ngohasalsamqmsted

m attend this meeting. Copies of these .lettom

am maimed.

’

mmmﬁummmmaydiqumstow
funpmgrmasof
lastmk. Aslindieated, Ihave
that
they
giwm afwmm-weeksandwillbe
mated

matingwithnrs.

weak.

GolcmdBr-illatmmmtingmt

Incidentally, Dr. tango has written a

ramp detailed

mammjmmxmmmmmmmm

hasmdyouacopyasmu.

Sinoemly yams ,
Max

Fink,

M.D.

Professor of Psydmiatry

Mszp

�</text>
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                    <text>January 3 . 1966

Professcr P.

B. Bradley
Medical Sdmool
Birminm 15, England

m

Dear Philip:
The latest group of respcnses 3° our invitation are enclosed.
Dr. Domino has accepted end Dos. Plugel end Kobayeshi have declined.
I have received an additional letter from Dr. chtechoveky which I

it raises.
By my count. we now have nine midpmts who have accepted
our invitatim and adding our cm pmsmteticm there
eleven.
am

enclosing became of the questions

,

‘lhme invitees

are

(Jeanne, chtechovaky, Verdeeux) have accepted
conditionally. Ilyutmenck has suggested that we accept his paper
to be mad and published. Thus, if all the participants make the
mating, there are fifteen presentations. With this may, we should
request three sessions. If, however, the conditional acceptances
em declined because of leckcf support, then there will be eleven
presentations. This is still emewhet long for two sessions, but
seems week for three sessime. Nevertheless, we should request
three sessions end trust that the discussion will fill in the
'

available time.

t

I m enclosing a pmpcsed prom for your consideration.
ﬁlm» the time is short, I believe
we should appmve this pmtly
and make the necessary fennel requests of the From Conmittee
for the support necessary for our ccnditimel acceptances.
Is there a need
Dr. Uikler indicated

mating in

two

for additional invitations? Incidentally,
that he was fully occupied during this

‘

other syupoeie.

If you will approve this prom, I will be pleased to write
to each of the perticipmte fomlizing
their acceptance.

�meoam Bradley

7

~2-

Jammy 3,

1968

Idomtmiftlnmmmumisandmtohm
Ihawﬂnfwmldalhmsmttoyou. Perhaps

abstracts,

inwmptmoe.mcmindicmthatamfmlabsmct
prubumtimatmtmofmmdngmuldbehelpm.

Hawyoumdewpmmmgnrdirgﬁnwblimﬁmofﬂﬂs

mix»?
My

best wishas for the

New

Year.

Sinmmly yams,
Max

Firm, NJ)...

Professor of Psychiatry

9.8.

W

wwuzmmkmmmmmwmmmmg
and Voj'udmky. and
not 61:11me with

had

mmmm'ammmwmmim.

�</text>
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                    <text>January 29, 1963
Dr. P. 8. Bradley
Dapartment of Experimental Neuropharmacology
The Medical School
Birmingham 15. England
Dear

Phil:

Enclosed are two copies of Figure 1 for the
paper ”Comparative Studies of Chlorpromazine and

Imipramine 2: Psychological Performance Profiles."
figure itself carrys the legend and I do not
think a special one is necessary. However, a longer
might be ”Figure l: Psychological tests in
legend
wh
ch significant changes occurred with chlorpromazine
and imipramine when compared to placeba group."
The

The group

of electroencephalographera

who

are

interasted in maeting in Birmingham in 196% have
circulated sown letters and we should have same
specific suggestions for the program committae
by

this

Bummsr.'

Hany

thanks.
Sincerely yours,

MISSOURI INSTITUTE OF PSYCHIATRY

”a! Fink’
Manw

Airmail
enc.

Direcmor

H. 'D.

�</text>
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                    <text>UNIVERSITY OF MISSOURI
51400

SCHOOL OF MEDICINE

Areenal Street

St. Innis,

Department of Psychiatry
Missouri Institute of Psychiatry

Area 314

MI

63139
5-6230

Mo.

September 21, 1965

Professor P. B. Bradley
The Medical School

Biminglm 15, England

Deer Philip:

I twat that your trip to Japan was a fruitful me. The
matings in Salxburg and Vim turned out to be excellent and
I had an opmity to dime our proposed eynpoeium with a
amber of investigators. Since returning home , I have called
some of the investigators included in my list following our
meeting .

The

subject of mticholinergic drugs and the associated
dissmietim of 3E8 and behavior appears to be

problem of the

of great interest. I have spokenvto Dre. White, Hiuwich,
Roubioek, Vojtechoveky and Voteve. Each has indicated his
interest and ‘I believe that they can make emtributions either
to the clinical or the beeic science aspects of the prom.

Ihweoalledbr. Domimmdfoundthetheisoutofthe
comm, but I reviewed. sure of his recent mm as presented in
e pant application mad I believe he will have a contributim
to

make.

Dnmitemmdedbr. (aim.

Idonotknowhim

peremelly, but I am enclosing a copy of his recent bibliography
and I believe he should we be invited. Dr. White e130 suggested
that Dr. Jam Biel or Dr. mo Abood be considered. Dr. Abood
presented am of his data at the Biological Psydmiatzy Meeting
and while it was of great
interest , its application
to em:- pmblem seem romte . Another mmndatim was that
of Dr. tango from Italy and, you may wish to consider him.

Wioel

In the elinioal aspects, in additim to Dr. Vojtedxovsky
Dr. Bantu of Emlagen, Dr.
my laboratory and Dr. Jenkner
from Austria should be widened. I have spoken to Dr. Bente
and they have material to present. I did not epeak
and Dr.
Jeﬂcner
but would consider writing to him. In edditim,
Dr.
to
I know that both Dr. Wilem of mm Caroline and Dr. Shagese
have done clinical studies but have not omtacted them until we
know the extent of the program In making inquiries about other

Itil fm

_

“

"Wﬁ‘m'.

.—.';-v

«-

r
'N-

..

r

-.

array-J

umu}rw:atmm

_

Itil

�Professor Bradley

Septmber 21,

—2~

European More, three

to me:
ms were pmsented
Wad

1965

Deniaenko

Pavlovian Institute
University, Mikhel'om of
and Anisetmov also of Inningmd. I know the work of Danismko
and ho has some clinical data on the use of mticholinorgic drugs
on head injuries. It may be intemoting to invite him to hear a
diffemt‘ kind of oxperienoe .

of

Hosea»:

I look at

notes, invitatims should be omsidemd for
Flagel), Bradley, Brimbelcanb, Domino,
Fink,
Home, Himich, Itil, ngo, Jezﬂmer, Vojtadlovsky,
Votava, White and Wilson. I think you should add a 11W!” of
participants and this will provide us with a sufficiently large
youp as a nucleus for the program.
An

the following:

Sim,

my

Boom (and

Thu following question might be presented to the investigators
as a focus for this oonfemnm:

are the mummysiological and behavioral
effeets o! the altom‘tims of brain function by
antioholinorgio drugs in animals and man? v‘wmat
am the bases for the awed dissociation in EEG

What

and behavior with those omnpomds?

Befom

we make

a specific program outline, we should decide
the liimlihood of their pmsentatim being
questims or some other aspect which you

on the participants and
germane to either those

may wish

to speoify.

mats and your advice as to

I should be glad to Mar your

the next step.

'

Simmly
Max

Pink,

youm ,
24.)).

meesoor of Psychiatry

Hszp
encloaum
oo’

”memm

qw—mnm

\

Dr. Colo

�</text>
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                    <text>September 23 , 1965

Professor P. 8. Bradley

The

mdioal School

Biminghan

15 , Englmd

Dear Philip:

I

have

just mosivad ,a 1&amp;1:th from Dr. Richard “hits with

swim.

some suggestions for the
Most have been sent to you.
He again
Dr... 81mm. Amng clinic-aims he has
suggest“! Dr‘s. Oatfeld,
and
I have cheated

mmds

Fmr

(30er.

the maent literature and find no publications showing
intamat in the subject within thus last four years.

their

He mammded, however, a name new to me, that of
w. H. Baker. I m sending you a list citing 802m of his
publications-m mud a short swam-y of his cumiculun vitae from
Man 05 Science. Perhaps you would wmt to consider
him as, one of the pmicipmts, and
so, I would be pleased

W

to call him.
I hepe these suggestima will

if

be

helpful.

Sincerely

Fink, 14.1).
Professor of Psychiatry

Max
v

”mp

your-a ,

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                    <text>September 24 , 1965

Professor P. 3. Bradley

Medial School
81min“ 15, mglmd

The

Dear Philip:
—-.4vw-VW~I'W'-"m

«fa-r,

»....'..

,—

"wt-w-

Imbmﬂutl shouléhavehnldupw lettertoyou,
for in this morning's mail, I mashed the enclosed
him from m. Vojtedmsky. I had spent a few hours with him
inSalzbmgdeimumMmkodhimmmmxdmms of
markers who may be interested in «our swim. Tm Mam

mica-

fmthat
msmtlmttoyoumliwthismkm
mansion. He reinforces his mats in the present letter,
a mpy of which is enclosed.

AWwWwWw-IHW’EW—"MP—vw

be

I think that both I». Votava and Dr. Vojtechovsky slmuld
mew advisabla to have mother mpmenta~

midsmd. If it

may

might be invited.
tive, Dr.
I have already auwsted. Dr. H. J. Hichelsm and

.rrv-

and perhaps

L-rm“-I-al

we

Dr. .Deniserﬁco

should consider Dr. Ilyutchamk as well.

It

seem that there are a goodly number of people working
in this man and tha opportunities for invitations mom much
better man we felt in mm. but me hear from you soon.

Var

,ymr.”

.p
y

Shamly yours ,

mind—a

-?.~

n).

~.-1-»

.

Fink, 21.1).
Professor of Payduiatry

Max

-.-wv-.-.

MIVWMW1'2_‘"w-Tvvﬂw

,«

14!": hp

-

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                    <text>Nowabor

3.5

, 1965

Professor 1’. 8. Bradley

The ﬂodioal School
Birmingham 15, Englmd
-

mar Philip:

I

I have carded out most of the instructions of your letter
of Member u. Invitatims have gone to the list of name which
are attamod, and I an sending you your invitation as a xerox
mpy of the letter to om of the other invitees. Please accept
this as a suggestion for you to write a title and a few sentence
abstract for our mo in the next few weeks.
Ibolimwoohcmld plmaoneday swim” amininmm,
Hud'nwilldepmdmtho
mdadaymdahalfasamﬂm.
invitatims.
our
moponu to
.

‘

,

0f the

names

in

tho-

fimt

group, invitations have gone to

I «a waiting ﬂmther information from
all
invitations
In
the
sending
to 1310 invitees in the Iron
you.
did
the ouggeotéon of two
mdomtmd
not
I
countries,
Main
invitation
believe
the
as
I
fmd has both a formal
Wars.
and pamonal aspect. If this does not seem satisfactory, please
advise mo and oiﬂmr you or I am send a second invitation.
mm I read yum footnote about a charter flight, I can still
moptimistmd'ifmmnmomsmttoyw,perhapoa
group rate om still bommizod. For this won, I included
the sontonoo at the bottom of page om of the invitation.
exoopt Hakajlma, and

mam mgarding Miss Taylor was added in response to the

notices from the Planning Canines.-

have an opportmity to moot with Jmthan Colo later- this
will approach the aubjoo/c of translation, discuss the
invitations and the mount status of our progm so that he will
will be mom
be acquainted with our progress. Humver, if
would you do
helpful for you to notify the Martin
formal
fashion.
so in a more

I

weak and

it

Wm,

Assam” Ihavomymmea, Iwillwvitotoyou.
My

best mgwds.
'Sinoomly yours ,
ﬂax Fink, NJ).

Professor of Psychiatry

�</text>
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                    <text>Mr

16, 1965

Professor P. 8. Bradley
Th. Maul School
Bimingham 15, England
Dear Philip,
Enclosed

the past

week.

and Bates.

{M
Ian»
inclined

the nplias which I have meeiwd during
mmay
include positive replies from Dre. Ham

m.
Dr.

Hence and Hichelsm have declined.

The

Ilyutmendc is most haunting and I an
to «wept his offer to have a paper submitted.

ImloavingSt. misforafmdmmdwwldlika

to wait another week to meeive whatevar additional replies
we are going to get. We should be able, with tan stat-ed
puticipmtn, to fomalnte a program by the first of the

W-

.

Hy

best wishes for the

New

Year.

Sindemly yours ,
Fink, PM).
Professor of Psydaiatry

Max

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                    <text>January

14,

1965

Dr. Philip Bradley
The Medical School

Hospital Center

Birmingham 15 , England

Dear Dr. Bmdley:
Dr.

Enclosed

is the revised Figure I for the report

and his associates on
Itilthis
arrives in time

I trust

My

"Drug Induced

to meet your deadline.

best wishes for the

New

Year.

Sincerely yours ,
Max

Fink ,

Director

mfzdk

E nolosure

by

Dissolution. ..".

M. D.

�</text>
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                    <text>February 22 , 1966

last letter and today I

waived

mm
Immtamoftmpmicipatimofm.ermd
Between your

menses in

titles,

W

have

some

has assaulted in the
mick). with your
of the following ensuring of the papers .

Rmmydiscmsim with Jamar: Cole, the
Wimhawmtomriabutaaoftodaymmmt
assmdofanysupport. Porthismamlhmincludedfm
Vojmchovaky.

pmbablcparticipmmmdafifthmmmswtimthatﬂm
fifthmynotbeavailabla.

'

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mating m issua agevised bulletin ifthat is necessary.
mat of the participmts have mama to tha invitations
with
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wt.

matasmyofourpmeecdingsshouldmtbapubmrnd. We
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was our decision at that time.

Since some of the participants have asked for copies of
thcpmgmm, Imsmdingomofmenclosedtoeamofm
invited guests.

not

Do

you think

it would be helpful

befom the session, either

for the participants to
bmakfm
an 'masday naming
at

orinamomrbndaynight?
Ilmkforwuwdtoseeingyouinmsrdngm.

‘Sinoemly yours,

Fink, HA).
Professor of Psychiatry

Max

11?sz

enclosma

�</text>
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mm,

19, 1966

Implnmdkdﬂmmoutmofmdiawsimawith
mmwbunntimofthnpmmdingsma
voluminm,mdmwithﬂuprommswhichyw have

mtlimdfnrthannuncnipta.

Whimtmorigimlsofﬂu

Wptsuithﬁnirfigwaﬁwmtswﬂlbomm
ymwiﬁdnamk.ncﬂmtﬁmmiclcsinwhmdsmuldbe
inmglmbyﬁnmdnfﬂnmﬁu.

Iuphmmwriuasmydimdmmdwam
mitimndiamly.
numeromanuinymmmmm
Ihnwmtﬂnmmipu.

Youdmmldwiumm. imp,

W,Wikkr,

Jacobean

“Jasper. Sinuvmwioinamigtmcringsummdhad

Wmmmam.1wcﬂlhimif1dnmtmiw
amwiptwithinnmubhtim.

Yammtinnﬁwtﬂiklnr'sropwtm pmvidamintmdmtim

nyhnutisfacmry,butlwou1dlihtowiﬁzholdfimljwmmtmtil

mhawhndamtnmmwmcfhiarmﬁm.
etc.

animus, alumna of proofs, indexing,
mm
mmsmtﬂmldamitmmﬂm

'33

InuitingfmSt.iauinmdmtilmmdofmy,thia

hmmrimms Aachmlst,Icmbamd
Hams: Mica}. college.
antntPaychiatry.
mmwmmm.mmvmty.mvork.
.

Ilcckforwdtoccnabomtiminﬁﬁsmm.
Simemlyyomw.
Max

Fink, PM).

Professor of Psychiatry

mxp
on:

Marque

Dr».

52

Vamrbilt Am

New

Yak. Nu: Yam):

10017

�</text>
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                    <text>August
Dr.

Mp Bradley

in,

1967

The Medical School

amningrm 15, England

new Philip,

I

have

requested by
mleted the editor queatiomaim
is enclosed
to than. A

Heavier and have sent
for yam infomtim.

it directly

copy

,

Sincerely yours ,
Max

Firm, NJ).

Professor of Psychiatry

Mfzkp

�</text>
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                    <text>Wmmm;m

w

,1“

F-

v

,

,

,

-me

,

.

wv -mn—WW.-_-—nw

~
‘

July 18,

1967

Dr. Philip Bradley
The Medical School
Birmingham 15, England
Dear

Philip,

The review of the compounds listed in the book is still
incomplete but should leave my hands by Monday. The summary
is complete and has only to have the citations added. This
will leave at the same time and should arrive soon after this

letter.

Thank you

fer your patience.
Sincerely yours,
Pink, 241.1).
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>Humvr'w-x-vvauvn—

_,

"wrwwrw

,.

,..

WV”

n

n

a“. W.w.r:,~.q¢;.~“

nulw

«

«canvas:

mwﬁw-mwvn“—0..“ W... «ems-1m“

,u~.vm.:».‘.;,r-.ym;

-

«MW

May

Dr.

mvru "a.

. wuv..~

y—wwv-

«y".-

.0"?

-u,w.,»n-,,..:,~u‘ mfg-,m-ww-rww

26, 1970

Philip Bradley

The Medical School

Birmingham, England
Dear

Philip,

Dr. John

The only nominations for Symposium 4 support are
Griffith, $400 and Dr. Ian Oswald,_$200. The other

participants have not asked

and I have not

offered.

If additional funds are available, I would appreciate
the opportunity to meet with the panellists and hold a pre-meeting
Such is best done about a meal and I may,
ask your indulgence in Prague.

session.

tight,

if

funds seem

Ivy-:1"

MW

"WA

the

I look forward to seeing

Duke symposium.

w—

My

m-

you in Prague,

if

not earlier at

best regards.

..

Sincerely yours,

“arm—l'nxmvr.-.'n

m:

‘ww—;

Nun—um

»

r

rnr

Mm;-

any;

.—...,

awn-aw»-

-w

~&lt;~w¢mz~w~w~a

r—s-xa-

vr-

Max

Dr. John

Griffith,

M.D.

Department of Psychiatry
Vanderbilt University
Nashville, Tennessee

Fink,

MUD

Dr. Ian Oswald

Department of Psychiatry
Royal Edinburgh Hospital
Edinburgh, EH10 5 HF, Scotland

._ .m

‘rw

w,

�</text>
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                    <text>NOW?

26 , 1965

Dr. Philip 8. Bradley

The Medical School

Biminghm 15, England

Dear Philip:

Earlier this week I mt with Dr. Cole and Dr. Brill informallly
during sessions of a special mittee. I submitted a list of the
invitees and a copy of the invitation. The Program Committee is
meeting on November 29, md“ they mooumged us to have the program
mleted by that date. I indicated that this was not possible but
that we would aubudtthe final program as soon as possible.
They assured me that we were on the list of symposia requesting
simultaneous thumletim and were particularly interested thatwe
had invited a ember of Soviet guests. Dr. Brill suggested that
did indeed come , special pmvisims would have to be made
if they
for Russim translation if it beam neoessary, insofar as Russian
was not an official language of the meeting.
,

With regard

to publicatim, m. Brill indicated that that

would

be the decision of another omittee, a publications casedttee', which
is yet to be appointed. He suggested, however, that in View of the
large masher of reports that me being planned for this meeting,
that would be unlikely that publication would be aocotmlished
through the GIMP directly. He suggested that you cmtact the
publishers and make the preliminaxy arrangements subject to approval

it

of the participmts aid the GIMP in March. In that way, we would
be prepared to make a definitive statemnt regarding publication
at the end of the meeting.

With regard to transportation eXpenses , Dr. Cole indicated
that the .oomaittea was placing the responsibility
in the hands of
the Emopean Committee of CINP. He suggested that we contact
Dr. Deniker directly. I have already received two replies requesting
tmspootatim grants from ﬁance and Amtria. Perhaps it would be
helpful to have you write to Dr. Deniker or discuss With More
of the mittee a mthod of allocating the available funds so
that we may beable to make some recommndaticms a few weeks hence!
As soon as I have few more replies, I will send them on to you.

�up.

My

'

November 26. 1965

~2~

list of invitees, we mined that Dr. A.
was outta! {mm list. While Immtawm thathohas
In reviewing the

way,

Wikler

studied

this problem
his interest and experimoe is such that I
mum like to contact him and ask tithe would be intamsted in
participating as a formal disamsmt.

Simmly yam ,
Max

Pink, 8.3).

Professar of Paydliatry

�</text>
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                    <text>November 9 , 1966

Dr. Philip B. Bradley

Meal

The
School
Birmingham 15, England
Dear

Thank you very much for your letter of November .3. The
draft agreement is satisfactory.
You are to be camerﬁed in
negotiating this instrument .

I recognized that the

'-'-'

“I

.rrzm""

required some work but
felt it was more important manuscripts
to send them on to you at the time.
If you wish to send any back to me for my editing, I will be

glad to do what I can.

1w

I

checked in

the figures of

Your letter to
will respond.
My

my

.
_

files

and did not find the legends for
nor can I recall having seen them.
sufficiently explicit and I am sure he

Voj teohovsky,

him

is

'-

best regards .
Sincerely yours ,
Fink, M .D.
Professor of Psychiatry
Max

mfkp

Vrgpavrra'

’

'

37‘

AV

»~:

-

Philip,

‘

“y“,

’
‘
.i

"W"""’"“"”v“&lt;

W12."

Warmeat'ws»mrnqur

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1966

m.m1pB.Bxudley

Birmingm,w

DearPhilip,

Wiethsigwdhgxmtwlﬁchisquite
Remarque's letter, Ihave

satisfactory.

1'0ka.

keptomcopyandImwndingtmbacktohim.
Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>April 6,

1967

Binningham 15, Ehgland

Dear Philip,
Enclosed are the first five proofs for the volmne. I found
that the publishers had done an excellent job and the few
corrections seem to be minor.

I

have one suggestion frcm

the articles. Placing Wilder's

discussion as an introduction seems not to place the symposium
in a proper perspective. As I recall and reread the papers,
there is a clear thread in the relation of EEG and behavior
seeming to be dissociated when the behavioral measures are

grossorwhentheEEGmeasuresaregmss. 'I'hereisperhaps
a greater association in the human sttﬂies because the
behavioral seasures can be more specific. I do not feel that
Wikler's introduction provides the same focus for the symposium
articles that we provided. Could we write a different introduction
and use the Wilder pages as a discussion? Or, could we
prepare a
short forward specifying the backrotmd for the conference?
I look forward to the next set of proofs. My best regards.
'

Sincerely yours,
Pink,
m
Professor of Psychiatry
MOD.

MF:kp

�</text>
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                    <text>May 22 , 1967

meeasor P.

B.

Wiley

The Madical Seine].

'

Biminghan 15, Exgland

Dear Philip,
-

'5'

l""!""}~€

‘;.;;g-;gg;.mzv,n'r:r.

I will be attmding the matings of the Mariam Em Society
inAtlantio Citywﬁlmldbeplaasedtospend-asmay‘mmas
are meessary to complete the editorial work on the book. If,
however, you would prefer to come to the United States a day
earlier or stay' a day later in New York, perhaps we could mrk
better in my offices. In either case, I will be pleased to

if

a secretary available and
you bring with you the revised
galleys, page proofs, up any otter matm'ial which may be helpful,
this mud be the best opporttmity for 118 to get together.
make

I
My

look

fmazd to Meaning ym in the

best mgwds.

Uni-tad

States.

_

Sincmely yours ,
Max

PM,

14.13.

Professor of Psychiatry.

Mf'ﬂcp

as.

Enclosed

is a (:1ch for my rmbemhip cause in the

C.I.N.P.

�</text>
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                    <text>May

1,

1967

Professor Philip Bradley
The Medical School
Birmingham 15 , England

Dear Philip,
Enclosed are six note galley proofs from the
cholinergic symposium. In addition, Dr. Itil sent
,

his

copy of the proof for this volume (No. 2813) and
have read and concur with his cements. Incidentally,

author's

I

anti-

me

is asking for 300 reprints without covers. If at all
possible , I would like an additional 100 for my personal
he

use and

it.

if

these can be supplied with covers , I

would

prefer

to the other proofs , there was little
difficulty with those of Carlton, longs, or Bures. With
regard to the article by Ilyutchenok, I find it very poor.
The text is poorly edited and the linotypist broke too
many words incorrectly. It is difficult to read. and the
style is too foreign for our usual audience .. I have marked
some corrections and suggest that you mark others. In
addition, the citations are incomplete and this requires
With regard

_

someone with experience with

the Russian literature.

Dr. Ilyutchemk uses the names Of drugs which are
in our literature. Perhaps , for his article or
for the book as a whole a dictionary of drugs with their
equivalent names should be provided.

uncommon

'

to the paper by Domino, I found the
present order of text and figures difficult to read. I
would suggest that the results, pages 16, 17 , and 18, should
become pages 5, 6 and 7 , following imediately after the
methods section. Page 18 slould end before the conclusions
and amnesty and the figures might appropriately be inserted
as pages 8 to 18. The section of conclusions and suzmxary
With regard

should then be included as pages 19, etc. Mﬁle this will
split the conclusions and summary froth—the main body of the
text, will place the figures in closer approximation to

it

the relevant text.

�Professor Bradley

-2—

May

1, 1967

There appears

to be a similar problem.with the report
set up, the tables appear on pages 2
hot are related to the text of pages 7~ 8. I have indicated

by Vojtechovsky as now

to 6
in the proof the possible location of Table I (page 7), Tables
II and III (page 7) and Table IV (page 8). This is equally
important for the figures which should be r€1ated to the text

wherever possible.

perhaps should be reset at half—page
it is confusing at present, or, the two
halves of the figure should be marked by captions of "Figure
and "Figure 9."
Figures

8

for the text as

and

9

There

is the use of a strange

Table

V

its

floccilegium. I
in my dictionaries.

do not know

all possible,

position.

8"

term on pages 9 and 1a does not appear
meaning and

it

should be related to the text of page 1n if at
I have indiCated its approximate relevant

and

I look forward.to the next galleys and to your comments.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
.

MF:kp

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                  <elementText elementTextId="102248">
                    <text>vvw‘

N

"'T.‘rl

an

many

"‘1'”va

_«
n-w

“nu-«1':

mewm'

,W‘

Vm“: ‘9'

~.--

“1......w.m-W&gt;,v.—n

‘.‘l”-~u.l:‘-

”mum m-‘vvu-ﬁr wprmpunlwr-(Wn -W\mewnaww

“I! ,vW-iw'v'uvwgﬁwdmKI-g‘m‘zl‘ﬂ'fo
~.x-A-~.w.--vmv

July
Dr.

sun.

we vows—:wmxmw
,

‘

mn-w-n

mwm'rwlnmnwwWWW.w- m, mm "mun,
_

20 , 1867

Philip 8. Bradley

The Medical School

Binningham 15, England

Dear Philip ,

I

Enclosed

hope

that

is a suggested text for a

it my be satisfactory.

summary

of the

volume.

In addition I have prepared a set of forms which include
cited in the various articles of the more unusual
conpomde. Corpounds such as mtphine, atropine amd ecopolamine
are not cited. All those which are used in the text, their
chemical forrmlla, trade names and marmfaotuxer are provided
on the pages. There are three cited items which I have been
unable to find in the available literature. Perhaps theee

the

names

are available to you.

and naphty‘zin.

Since
have asked

I

They

are bensazine

on not sure of the form

BA 1&amp;33 (WH

that skould

”8%),

be used,

I

secretary to prepare these on individual sheets
and if the publisher will provide a foam, it should be a
simple matter to prepare the citation list.
my

Sincerely yours ,
Fink, Md).
Professor of Psychiatry

Max

M‘mp

».»

.

�</text>
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                    <text>September 26, 1967
Dr.

Philip

8. Bradley

Center for Advanced Study in the Behavioral Sciences
202 Junipero Serra Boulevard
Stanford, California 94305
Dear

Philip.

Congratulations on your opportunity to study in California.
the opportunity fulfills your expectations, for it has
been spoken of most highly by so many scientists who have preceded
I hope

you.

I am writing to obtain some up-to-date information regarding
the book "Anticholinergic Hallucinogens.” Are all the galleys
and page proofs approved? If not, are there any further page
proofs that should be checked?
_

Is there anything else that has to be done? Or, am I to
that the editorial work is completed and we are merely
awaiting the publishers details?
assume

Incidentally, I have interested Dr. white in a study of
an anti-narcotic, cyclazocine, and hope that he will have this
work completed before he joins you in England next year.
My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

Mszp
P.S.

If

you have a few minutes, please

(212) 369v8488.

call

me

collett at

�</text>
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                    <text>April

an Phillip

25,, 1966

Bradley

The Phdiodl School

Elimination, England

Deer

Phillip:
I have devoted the past

two days to reviewing the
manuscripts available to me. and in preparing a summary
of our proceedings. The manuscripts and my nous are
going out separately today. There is one special question

is related to the too dommnts of invited participants.
Ire. Ilymhendc and Jermr. whioh were not presented at

which

the meeting.
quite
.

I

e

have found

that Dr. Ilyuohenok’s manuscript id
amend its inolueim in the proceedings.

good and would

With regard

to Dr. Jenkner, I ampuzzled.1 have

available a four page abstract. a copy of mic}: is enclosed.
Wlbelimthetmoftbemteﬁalwouldbequite
relevant to the discussim, and, as it deals with a
peculiar state of altered omeoimea. I believe it my
be considered for inclusion. Harem, I do not have the

full manuscript. and this would have to be solicited. It
wand be a. delicate matter to solicite the musoript and
than decide as to ite suitability. I am therefore bending
theebetmottoyouendwould suggest thetmdowite'to
no. Jenlmer asking for the full madam. perhaps providing
new caution that it should be submitted for consideration for
Mlleetion. If you concur, please write directly to him, or
I will be glad to do so.

Inﬂuemuswipt whiohlheve justreed, lemmeking

neither editorial ohnges nor oomotim of style. since the
smoifio guidelines for this volmae are not available to me.
I would be glad. however, to make and: editorial and typographical
suggestims if we can agree on the necessary style guideline.
Sincerely yours.

MF/jnh

Pink. “0-D.
m
Professor of Psychiatry

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                    <text>Hard] 23, 1967
Dr. Phillip Bradley
The Medical School
Birmingham 15, England

Dear

Phillip:

Ithas beenmonths since therehas beenany activity
here with regard to the CINP volume. What is the present

status? Are the nanusmipts in final shape or in the hands
of the publisher or??

IsthemanytlﬁngIcandotobeofassistance?
My

best regards.
Sincerely yours ,
Fink, M.D.
Professor. of Psychiatry

Max

MP:kp

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                    <text>,
.

March

.

._,...,._,~,..

vw-v;—-......,.—._

_.

Dr.

l9, l968

Philip Bradley

The Medical School

Binningham
Dear

l5,

England

Philip,
When I

received the complimentary copy of Antioho£ineag£c

Danes I was very pleased. I think the
one and I look forward to the reviews.

presentation is

a good

wrote to Dr. Remarque concerning complimentary
copies for the participants, I found that we had agreed that
complimentary copies would not be sent to the authors.I
regreted this decision and have authorized Dr. Remarque to
send one copy to each of the participants at $7.00 a copy.
When I

I

trust this is agreeable to

you.

My

best regards.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

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                    <text>April 22, 1953
Dr. John Paul Brady

Indiana.

Medical Center
mimity
Street
maxim

1.100 West

Indimepolis 7, Indiana

Dear Jam:

I

me

encloaing a copy of the application.
you please
each item except those which appear imlevmt. Return
of year miculm vita.
to me with
am

mute
this

mm

Imlooldmfomardtohavingyouvisitwithusmin

attbetimoftheAPAdeemldbeebletomrkouta
time.
with
satisfactory armamt

at that
Pleasesmdmetmairplm ticket etubamwewﬂlhe
able to
you for the trip.

mm

you

-

Simerely
Max

1“!me

Fink,

Director
’

your-e,

M. D.

�</text>
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                    <text>March 2, 1991
David L. Braff, M.D.
Chairman, Membership Committee
Society of Biological Psychiatry
UC-San Diego
San Diego, CA 92103-1990
Dear Dr. Braff,
I have been acquainted for about four years with the work of Dr.
Chittaranjan Andrade of the National Institute of Mental Health and Sciences of
India. He is a talented investigator who has tackled a topic of little concern among
neuroscientists, that of the behavioral effects of induced seizures in man. He, and
his associates Drs. B. Gangadhar, G. Swamineth, and S. Channabasavanna have
been very productive in their research into clinical ECT. Dr. Andrade also spent a
fellowship year in Vienna with Drs. Ianger and Koinig in studies of neuroendocrine
effects of ECT.

Dr. Andrade and his associates were instrumental in organizing the first
Conference
VAll-India
on ECT this Fall; a meeting which I understand was most
successful in highlighting the national progress in clinical use and research into this
hardly used therapy.
There was a time when the Society of Biological Psychiatry (formed as a
union of biological, electroshock, insulin coma, and carbon dioxide specialists) was
interested in ECT. If that is still true, then Dr. Andrade is a fine example of the
new breed of clinician/researchers whose work should be encouraged; membership
in a US. organized society may do much for him, and I recommend him highly to
the Society.
Sincerely yours,

Max Fink, MD.

Professor of Psychiatry

19505, a winner of the first A.E.
Bennett Award, and winner of the Gold Medal Award of the Society.

PS. I have been a Fellow of the Society since the

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                    <text>May

8, 1968

Dr. Leonard Brahan

Endo laboratories
1000 Stewart Avenue
Garden City, New York 115333

Dear Dr. Bmhan:
Enclosed

is

a.

copy of the report which we recently

read both in Tarragom and in Atlantic City, I believe
it will be published in the Proceedings of the CINP.
Sincerely yours ,
‘

Fink, 1w.
Professor of Psychiatry

Max

MF:kp

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                    <text>war-was“

wa—

—

Enron 18. 1963

Dr. Leonurd 5. Brnhnn

Ohns.

235

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Pfiaer

&amp;

Cowpany.

East hand Straet
Yark 17. New York

Ina.

Daar Dr. Brahonz

It at: g plantar. to ahst with you satin 1n Huahiuaton.
writing to remind yea that we would be interested in
reeeiving sunk information as Pfizer any h‘ro .tailable regarding
Bonzquinmmide. Dr. Gershon is gov establishing laboratories god
r-I trust that we will be able to undertaxn gang‘studiaa'by early
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summer.

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I am taking the‘libcrty of enclosing a brochure describing,
tho Mitsourl Instiﬁute of Psychiatry. The turneuyear training
program in psychiatry a$ this institution is now supervised and
airectod hr thn stuff of thy Inititutd. While tha alphanis a!
tan staff is an studies in tho biological aspoata of psychiatry,
tho_trnin1na program is balanecd with lecturco and oxpurience in
bath $ndiv1dua1 and group psychotherapiea. 0n the oecaaion of
yuar‘nnxt viait ta St. Louis. I uuuld bu plonana to tutu you
through tho Institute.
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Octohcr 15, 1973

17}?

«V

lwzam'H-"a-W.

«r
Wt"

"m1“

W

"W'RP‘W

&lt;x&lt;wﬁwn~

Knrv¢y Blucntonn. M.D.

Bayartnnnt of Psychiatry
‘Ironx—chanon Hospital
1285

Fulton Avon“.

aroma.

New

York lOéSG

Dear Egrvey:

I-raarn: that I was unnuccoolful with A. B. Robina.
I have not heard from Dr. Clark. and in checking with his
aosociates I was told that the firm has no program for
the support of local noctingn.

L

EU

best rczardl,
Sincaraly yours.
ﬂax Fink, M.D.

Profalnar o! Payebiatxy

�</text>
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                    <text>January 9.
Dr. $1133 Braley

Dav Corning Center

Midland, Michigan

for

1969

Aid to Madical Egaenrch

Dear Dr. Braley.
Thank you

far your

meat infarmative éiscussian and the
reply.
wera'quite remarkable, and the patant
application for a Silicone carrier for drugs was most helpful.
It in apparent that this mathod may be useful in two of the problems
of direct interest to ua~~ the treatmaat of opiate addiction anﬁ
of chronic ptychoais. In addicts we weuld be intcrastad in the
continuous slow raleaaa at a nercatic antagohist, such as cyclazocina;
and in psychosis, the release of an antipayahntie like the cannon
prompt

The papera

phenothinminea or thiaxanthanea.

I will take the material that you nan: and prepare u ruport
to on: staff. As soon as we have giltified our interest, I truat I
may write to you for further advice.
hany thanks for tha opportunity to became acquainteé with
an important medical advance.

Sineuraly yours,
Fink, M.D.
Professor of Psychiatry

Max

mf/

�</text>
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                    <text>Jammy 10, 19%

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prior approval of the Dinotw at
Suoh permission is not wdimrily wanted, «apt at the

moms.

must of
animotwofthosmsmimmmmﬂmpatimtmybeamiaunt.
.

I bclim you shmld

that two of the nation's finest
in
your State,» in (Mango, at
m
whim Dr. water H. Body
Imam ofHospital,
and Gal-sour; State
Galosburg, Illinois .

mound: and matmom comm
the Illinois Stat:

knew

Mario mm
Wow
ofwhioh Dr. WE. Maxis tho Mmotorofmm. Immld
mom, that you omtaot either of these institutions regarding your
13

Sincerely yours ,
Pink,
m
Dimotor
Brands

M.

n.

�</text>
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v

,

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-m...

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m".

rumm— -.——.'—‘.~,..-u

~‘»x.vu.l‘-—(‘r .»..~_.r

October '19, 1937
Ms. Christa Brandt

587 Echo Valley Road
Salinas, CA 93907
Dear Ms. Brandt,

._

Your request for information regarding the psychiatric phenomenon of
multiple personalities was sent to me for reply. This organization tocusses its
research interests on biological treatments in psychiatry, and we have little
experience with the problem of multiple personalities.
Our recollection is that the classic study "Three Faces of Eve" was written
by fellow biological psychiatrists Corbett Thigpen and Hervey Cleckley of Georgia.
The book was published in 1957 by McGraw Hill and should be in your library. I
commend it to you.
Good luck in your studies.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry

.-_

_,—-mwp~ws

�</text>
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"awn-w-

~

\- m—s-uu—v-n-rr—w-v-rwrwwvvvv-m—uws

,..._

v

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uwv V-‘r—W&gt;a’-Yn~lswrw—m~¢wr-.‘

-

.4

-

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»:

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1-

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‘wn-Wy' um. q-ww

h

”Mg/MM.

19 December 1979

-

John T. Brauchi, M D
Professor and Chairman

Department of Psychiatry
Louisiana State University Medica1 Center
P. 0. Box 33932

Shreveport, Louisiana 71130
Re: Dr. D1iver T. Nikd1ovSki
‘

Dear Dr. Brauchi:
Dr. 01iver Niko1ovski was a member of the staff at the New York Medica1\
Co11ege during my tenure in 1966 to 1972.1nitia11y, he served as a
research psychiatrist in psychopharmaco1ogic studies; 1ater. he was the

c1inician in the

Day

Hospita1.

.

“

=

During the time he worked with me. I found him a 10ya1 and dedicated .\.
worker. He is Sincere, honest, and responsibie. He was we11 1iked by
the Staff and the patients and he was enthusiastic to carry out the studies
we designed.
Dr. Niko1ovski is an exce11ent member of a c1inica1 team. and he has the
ski11s to carry out c1inica1 functions in the management of the treatment
of the menta11y'i11. I recommend him for a c1inica1 position. without,
hesitation. 'With regard to his capacity—as a residency trdhing director.
I am unabie to give'you any definite opinion. since_he did not function
in this ro1e during his tenure with us; nor was I ab1e to observe his
teaching sessions, since these were 1arge1y part of the c1inica1 teaching

sessions.
I

,

trust this information is useful.
Sbncere1y yours,

MF:BK

Fink, M.D.
Professor of Psychiatry

Max
'

.

_.

\

�</text>
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                    <text>STATE UNIVERSITY OF NEW YORK AT STONY BROOK

Health Sciences Center

-

School of Medicine

Department of Psychiatry and Behavioral Science
Psychopharmacology

—-

EEG

Laboratory

Stony Brook, N. Y. 11794
Phone: 516-444-2447

_

December 22, 1976

Ms. Marion M.

Brault, Staff Assistant

Cooperative Studies Program
Veterans Administration
Department of Medicine and Surgery
Washington, D. C. 20h20
Ref:

lSl—I

Dear Ms.

Brault:

I plan to attend the Veterans Administration
7 and enclose a copy of my
abstracted C.V. I look forward to reading the material
submitted by Dr.Karacen.

meeting of February

Sinc rely yours,

Fink, M.D.
Professor of Psychiatry

Max

Mszg

encls.

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                    <text>March 1, 1967

Dr. Manfred Bram
3‘45 West 58th Street, Apt. 5T
New York, New Yur'k 10019
Dear Dr. Bram:
Your letter
by Dr. Freedman.

of February 8, has been referred to

I

would be pleased

call my secretary at

369—7900

Ext.

2H8.

Sincerely yours ,
Firm, M.D.
Professor- of Psychiatry

Max

me

to see you. Please
’

�</text>
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                    <text>28, 1969

May
"r
:.

r:

‘wz‘u—t

"aw.

1-k

w
5

Dr. Mary A. B. Brazier
Brain Research Institute

University of California Modical Gunter
Loo Angolan,

California

90024

Dear Mollie,

Enclosed is a copy of a report describing a mathematical
approach to the EEG response of pontothal. We have workod on

this for

you

in

I

many months and you may

December.

would be very

recall

grateful for your

my

discussing

comments and

‘
.

My

best regards.
Sincerely yours,

3514“"‘w’ﬁ‘u'urﬁr-ran’wr";wu

Fink, M.D.
Professor of Psychiatry

Max

v?

getf-tﬂxku,

m.”

,.-

;

”W.

.n"

.n,_

wnwmamm'ﬁ-‘m

~.-.'"‘?w‘~s.‘;

4"

“-W-I"

‘Wﬂf-Wﬂv

4275'5‘

Mszp

with

criticisms.

H..-

m-

it

�</text>
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                    <text>February 26, 1966

Dr. ﬁery A. B. Brazier
Brain Research Institute
University of Cslifornie

st Los Angeles.
Los Angeles, eelitornis
Dear Dr.

Bresier:

In oorreoting the gslley proofs of the forthcoming bibliogrsphy
of srticles on EEG ohenges with psychotropic oregs in men.
Dr. Ajmone—Hsrseu suggested I may have omitted some to be fauna
in your recent review in gligi§_l EnsEggoology gng Ihgz_ggg;1g;.
Indeed. I did, end I so sdd1ng those which amplify the bibliogrsphy.

noted e recurring note of apology - that little, oh,
could
be learned from studies in men! And. as you
little.
indicste. this is true. But. the envoi is charming - so charming.
indeed, that I would like to quote it in its entirety in the

At

so

first. I

bibliogrsphy.

It is true that

the effects of these drugs are unolesrly defined;
that the reports are contradictory (ss you indicate for reserpine
end ioiprsoine); end that we leek theoreticel models for deserih~
in; the observed changes in the 336. not. could it not be that the
lock of definition. the discrepancies. and even the leak of models

are a reflection of the methoos end the sttitodes applied to the
problems these pest few decades? By methods, I mesa the use of
_dssoription rather than quentificetion; inadequate definition of
population sod look of swereness of individusl differeooes of sub—
jects; sud disregard of the pharmacological principles of dosage.
route, rate and dorstion of drug administration. Too often. also.
oethodologiesl limitations have interfered with enelysis, so is now
true for the spplicstion of insensitive recording systems in electroencephslogrsphy ss spplied in sneethesiology; or the indiscriminate
use of sedsting drugs in psychiatric services.

�Dr. Kory A. 3. Erotic:
2-26~6&amp;

Page Two

cttitodos, I rotor to the rnportc of drug affects at ”normal”
reflecting a pathological modal rcthor than a
physiological continuum of change in activity; and to the goncrnl
By

or "abnormal“.

donigrction of studio: in man as being ”uncontrollod”, ”inclcgcnt".
and "not.bcnic". Hapcfully, your rovicw and especially your cnvoi
expresses an optimistic view thct may havc c salutary offcct.

I have three spacific commontl. The rcforcnoc on pogo 103 to tho
dcuynchronizing effects of cnticholincatcrcscs in anionic having
"no

The

Wu
mm.

parallel in clinical electroencephalography"-ic inaccurcto.
studies

of.

Rowntrcc

25 A}.

(,1.

Naomi...

5951

W

£ayg§;a§”_;_: 47. 1950) demonstrated that DFP had a similar clcc~
trographic affect in can (while Grab 35.5;
4,.
ﬁgsa. §;; 257, 1947, reported DFP electrical coiturorliko activity
in man).

'

’

.

By describing the cifccta of reserpine an "unlikely that the drug
has any speciﬁic effect on the EEG, the signs of drowsiness being
merely thooc secondary to the general rclcxction ..." (p. 104);.
chlorpromazinc as "the appearance of normal drowsiness" (p. 105);
and imiprcuinc as "... the effect on the alpha rhythm
... may
merely be a nonsnccific indication of the degree of drowsiness"
(p. $35); the specificity and individual differences of the electrOgraphic effects of those drugs are lost. Like description: of
records as "normal" cnd "abnormal" which deny the possible significance of frequency and pattern changes. descriptions of a record as
"drowsy" and "due to drowsiness" deny the possibility that there
may be differences in the pattcrnn and imply a mechanism of action
which may not be appropriate.
‘

it not truc that similar electrographic patterns may be soon in
toxic stator, inflammatory conditiont, dogenorative disccsc cnd in

15

similarity of the graphic
pattern nocoscatily roilocting the some pathophyoiology? Similarly,
may it not be unproductive to doscribc the affect: of various drug:
immature and aged normals, without the

under the caption of "drowsinooc"? in a recent study using an clot“
tronic frequency analysis. we clearly separated the drug effects of
chlorpromnzino and imipraninc, even though both compounds had many
“nutrition
1: 36b. 1961).

M. m.

.

Wm

to the mochcnism of action of imipramino, it may not be known but the difference bctwccn imipraminc and MAO inhibition was exprcloa
ad in the
1959. g: Spociol
gum 52'12
Supplcncnt. At that contcrcncc. the anticholincrgic activity was
cmphcciccd by 3133 (p. 879) and myself (9. 5169) ~ and that. saga
gutionc have uincc boon confirmed by Coir-corona 35 g; Q. rigor?As

53%

m.

9,: 224. 1953).

�</text>
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                    <text>Apml '4 , 1966

Mar

Br. Katy A. B.
Brain Research Institute

adversity of Califm'nia Medical Center
[as Angeles, California

9022“

Dear Mollie,

Ihadﬁmplmmoflmdﬁngonl‘ridaywithbr.J.Rmrqm,
with him

of Elsevier. and

:3in

the possible publication of

tinteemicalmualenelosedmmith. keuggsetadthat!

memawpyaadindieatedthathemuldmymmepinim

ammmmmldmimmmdmkmofmefthia
mm. Be ﬁxdieated

material in your pmposed international

tlntynumplamingtomdngup—to—dateﬂmmﬂndeof
miter Marcia of EEG as described in your EEG eupplmnt .

Imalmemlosﬁngampyofamportpmentedatﬂn

Imsmimmmr,mmmofthaappﬁea—
tieminmatwdatail
ItistmappHeadmtopeyW
u ' reclaim that intanstusandommsmt studies
mdefinidwmwltsﬁmmminemdedintmt
‘

Simmly yams,
Fink, Md).
m
mecaaer of Psydxiatry

�</text>
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                    <text>September 11. 1966

Dr. Mary A. B. Brazier
Brain Research Instituto

University of California

Madical Cantor
Loo Angelou 24, California
Dear Dr. Brazier:

like to thank

for permitting

to quote from your 1964
review in tho forthcoming Supplomnnt 23 of the EEG Journal. I have
had occasion recently to prepare a report on my views on tha subject
of EEG and drugs for a psychophormaeology group, and am taking the

I

would

liberty of reading
In

May,

you

mo

you a copy.

I had the opportunity to

visit

the Brain Research Institute

on occaaion of the APA mooring. I was vary much impressed by the
many programs and projects in progrooo. I oallad your office but
you ware away.

would very much liko to have an opportunity to visit with you and
perhaps opand some tima obsarving your study programs. Perhaps.

I

visit is possible. I might also obsorvo some of the
othar programs at the center. An I am fairly freo to not my own
tins schedules. would it be possible for mo to visit with you this
Fall? I am planning to ottoud the Santa Fe meetings and I am free
tha Hook thoraaftor (ﬁntil October 10). I also plan to be in San
Francisco for the Fall Joint Computer Conference, October 27-29,

whoa such a

and can make any tima availablo from October 30 to November 4.

you will be available either of those times, I shall be grateful
for the opportunity to visit with you.

If

My

best regards.
Sincerely yours,
Pink.
Director

M81

MF/jb

MOD.

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                    <text>October 6,

196%

Brazier
Brain Research Institute
University of California Medical Center
Los Angeles, 214, California

Dr. Mary A.

B.

Dear Mollie:

I was disappointed in Santa Fe that you had not come.
There were a number of questions that I had to discuss with you.
The matings were excellent and Don Walter read your paper very
Your pictures, and Grey Walter's description stimulated
in the recollection that the changes that you see in the
scalp frequency pattern are very close to those seen with the
administration of imipramine. I am taking the liberty of en—

well.
me

closing

some photographs

_'

of frequency spectra.

In studies with Imipranﬁne there are two additional
observations. Borenstein has déscribeé dysrhytmic patterns in
scalp electrodes and there have been occasional reports of
spikes in patients receiving imipramine. Also adolescent sub=

jects

who

are psychiatrically disturbed have

become

excited and

administered indpmne.
While you have presented the analysis of the frequency
spectra when the depth electrodes showed spikes, was an evaluation of the frequency spectra carried out to determine if
Spikes were indeed present when the scalp electrodes showed the
oranges in frequency spectra?
sham acute episodic behavior disorder

when

,

In additim to the figures which are sufficiently ex—
planatory, I am enclosing a copy of the report in which I give
the statistical data on chronic imipramine admnistretion and
this shows that there was a decrease in the amplitude of alpha
activity, and an increase in delta and beta (22—33 cps). While
this table does not show that the delta and alpha changes are
significant, they become so in the final report which is now in
press.

�-2Dr. Mary A. B. Brazier

October 6,'196u

I am also taking the liberty of enclosing a copy of
the report that I presented in Bimﬁngham on August 3lst. It
was while writing this paper that it became clear to me that
an important addition to the data available to me would be obtained from studies in patients with depth electrodes. When I
visited the B.R.I. in May, I was escorted by Dr. R. Walter who
showed me a patient in whom EEG's were recorded fmn both the
scalp and the depth during varieties of psychological task performances. You have indicated that infatuation obtained concurrently from the depth and the scalp would be more favorable
than fmn the scalp alone and this latest report supports this.
Would it be possible to visit with you and spend some time ohserving your study prog'emsz I am free to set my own time sch-—
edules and should like an opportunity to explore the possibility
of carrying out some systematic observation of drug administration
in a subject with both depth and scalp electrodes. I do not 1mm
much of the politics of such. an mangement but believe I can
utilize the resources of try Institute to support all necessary
and proper expenses .

It is possible for me to justify a trip to California
to attmd the Fall Joint Computer Conference October 27-29 and
should like to visit with you, if only shortly, either just
before or just after those dates.
I shall send this off today and will call you in the early
of next week in the hope that some arrangements can be made.part
Sincerely yours,

PM,
m
Director
mf/ is
e nclosures

MOD.

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21. 195::

Dr. Mary A. B. Brazier
Brain Research Institute

University of Califomie Medical Center
los Angeles, 2h, California
-

'

Dear Dr. Brazier:

Wthepastmeklhevehedenmberofdw
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wicrﬂmingﬂiptoCelifmie. Iwenttothmkymfor
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yourhelpinuekimgﬁerntswitthm.
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laterdetawhmlageinhmthejustiﬂeationofflm

www.mmllmywmdpeﬂupsmcmﬁmdﬂcause acne of the questions, thet are of interest.
‘Heny

thmks for your help.
Sincerely
Mex

fink, NJ).

Dimctw

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�</text>
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.; m.-

5,2,4... ... “an.

,

.. (h

February 15, 1989
Dr. Steven Bressler

EEG Systems Laboratory
51

Federal Street

San Francisco, CA 94107

Dear Dr. Bressler,
would be pleased to collaborate and consult on your project
"Neurocognitive Pattern Recognition of Drugs of Abuse". Studies of the effects of
dependence producing psychoactive drugs, especially drugs used for recreational
purposes, are timely. Our early studies which depended on quantitative com puterbased assessment of the electrical activity of single leads were productive, but
were limited by their expense and technical difficulty. Recent achievements of
multi-lead quantitative EEG assessment, such as those undertaken in your
laboratory, corn pel the re-assessment you propose.
i

For your records, I enclose a cepy of my c.v. which details the studies of
cannabis and opioids which i did with Jan Volavka, Peter Irwin, Rhea Dornbush,
Costas Stefanis, and others while at the New York Medical College, 1966—1973.
Citations to our pharmaco—EEG studies are also detailed.
Good luck in your studies.

Since rely yours,

Max Fink, M.D.

Professor of Psychiatry
IRS 11-2133166

�</text>
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                    <text>February 11, 1971

Ir.

Richard Brezinski
Convention Manager
Arizona Biltmore Hotel
Phoenix, Arizona
Dear Mr. Brezinski:

are interested in holding our meeting at the Biltmore,
but the planning group will be unable to make a final reonmmendation
until late this spring. In the event the decision is affirmative,
We

I

will call your office.

Sincerely yours,
Max

Fink,

M.D.

Executive Director

Mszt

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                    <text>7488-00688

7

January 1974

Alan Ran-0y, M.D.
Madicnl Consultant
Cantor for Studies of

,Narcotic

and Drug Abuse

ﬂntionnl Institutn of Hinttl Hoaleh

5600 Fiuhct's Lane
nockvillc. Haryland

20852

2.:

HSM

52-73-260

Dtlt Alan:
0n Gotcha: 15 w. roquoutod parmiauion to transtar $475.00
from 0.8. Travnl to Foreign T2£VI1 to permit my attendance at
tho HBC~HAS Qualiﬁes. on Problonn of Drug Dapandonca matting.
which 1- beta; hold in Marion City, March 11-14. 1974.

I

would

apprcciatc tho contract apptovsl for thin transfer.
stuccrcly yours,

m
M. Md).
Protcnnor of Psychiatry
Mileis

�</text>
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