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                    <text>Department of Psychiatry and Behavioral Science
Health Sciences Center
State University of New York at Stony Brook
Stony Brook, New York 1794—8101
telephone: (516) 444-2990
1

StonyBrook
May

S. Reddy Pasem, M.D.
1301 River Oaks Drive

Colonial Heights,

VA

26, 1987

23834

Dear Dr. Pasem:
Thank you

for your inquiry.

I

will not

be

available to

course until October. I think your needs can well be
served by the program at Duke University.
Duke University has just announced its programs in ECT.
I
enclose an announcement and suggest that you contact Dr. Coffey
directly. If that does not work out please get in touch with me
after the summer.
supervise

a

Sincerely yours,
Max

Encl.

C.

M.D.

Professor of Psychiatry

MF:cjp

cc:

W

Fink,

Edward

Coffey,

M.D.

�</text>
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                    <text>August 17, 1971
Dear Dr.

Pasic,

I have received the letter of recommendation from my
good friend Dr. Hajnsek, and I welcome your inquiry. Inregret,
however, that I do not have an opportunity to provide residency
training in my Division. I did enquire whether our Department
may have an opening, and find that all openings for 1971-72
are filled.
The préncipal openings of my acquaintance are in
the New Yor State Department of Mental Hygiene hospitals. You
may wish to write to:
Dr. Alan Miller
Commissioner of Mental Hygiene
Albany, Nut York

or

The
may

Dr.

Israel Kesselbrenner

Kirby Manhattan Psychiatric HOSpital
Ward's Island, New York.

first

provide you with general information; the second
have openings as his hospital has recently been separated
may

as a special unit in

New

York City.

You may mention my name

both well.

Good

to either

man, as

I

know them

luck.
Sincerely yours,
Fink, M.D.
laboratory whenever you are in
Max

P.S.

are welcome to visit my
York. I suggest you call a few days in advance (212
369 7900) as I am often out of the city.

You

New

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                    <text>June 17.

196&amp;

Dr. K. £atcisky
Universitits—ﬂervenklinik
14. Lazarcttgasse
Vienna 11

Annttic

Dear Dr. Pataisky:

laboratories of the Miasouri Institute of Psychiatry.
devntcd to studies in clinical neurophysiology and psycho—
pharmacology, are interested in participating in the 1965
interactional mactinzs. We would bc grateful for any further
information rcgcrdins registration, participation in symposia.
and frat cannunicatians which may be made available from time
to time from your office.
Thu

With

all bust

wiahcs for the success of the 1965 meetings.

Sincerely yours,
Fink,
Director
Max

MF/jb

M.

D.

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                    <text>M

m—vw

-.-r..-u

yw-

.m.

n.

W3? 15, 1963
Dr. A. Smear Paterson
2 Dovomhim Place
bondm W. 1,

mm

Dear Dr. Peterson:

than of Dr. H. mummhas
at than
Immiting
applied for a position at the sswri Institute of Psychiatry. Dr.
unﬁnhm Mmodﬂaattnmuldlikatemtoﬂmﬁtams for
This
research
~

facility is a
«no,
clinical psychiatric mam. In writing
hem, Dr. until: will be mmible for a. small bled: of patients,
must of whom suffer with a mjar psychosis.
additional paydﬂatﬂe experiments.

tar with

heavy

Wis

on

'

grateful for your mmﬂatim regarding tr.
Lantin, his personality. his ability as a. young paydaiatﬁst wad
ymn‘ animate as to his potential'for mt}: as a mum: scientist.

I

would be.

I have mntly read your latest
est. Congratulatim on a fine job.

book with

midamble inter-

Simiy ycum ,

nm-‘Km-

._.N,mmw_.

m m,
Dima’cor
Mfzmlg

MI Do

�</text>
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                    <text>7383.605

Dr. Jannthnn Cole.
Boston state Hospital.
Benton, than. 0212b.

Dear Jon,

or

I an available for the

313%.

or June

In the

A??A

13%.

Couneil on may 30th,

liat of people invited,

Donald Klein havn baen emitted.

Kenry

Brill and

Aloe. unless ynurar Jerry are assuming full
rcaponsibility for the arrangaments, you might wish to
invite whomever is assisting you for tha arrangamanta
aanmittee. should you think it necessary.

Sincerely yours,

Max

yink,

M.D.

Professor of Psychiatry
MP/id

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                    <text>NOW}: 15 ,

Dr. Ronald Paul
78

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771

St.

Jane's

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1963

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mm

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am

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Myanverymm fmyminqury. m mammal Imtimte
of Paydﬁatryis mmmminingmorofmmMimof
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trumpet-team.

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fw'mndidms

who

I an enclosing a «swiptim of'the Institute. as wall as an
applicatim for appointmnt to this position. If this
intemsts you. I would appreciate the mm of the application a

Witty

anallphotmmmmmmofatmsttmmfems.
Sincerely yours ,
Max

Fink,

Director

M. 1).

�</text>
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                    <text>‘

W.

:3,
MM

if

December 15 , 1963

Dr. Ronald Paul

78 St. Janes's Avenue
Beckermam

Kent, England
Bear

11‘.

Paul:

The enclosed application is a formal form in use in the State of
Missouri. This application will effectively give us a copy of your
curriculmn vitae. If you prefer, a complete miculwn vitae may
be submitted in lieu of this application form.

Positions will be Open at the Institute as of July 1, 1964 and
again January 1, 1965, as our research program develop. All
appointments are made on a provisional basis for a six nonth period.
Tenure in y'ade is then provided through the Institute for such
period of time as is agreeable both to the candidate and the Institute.
Appointnents are made under the rules and regulations of the Division
of Mental Diseases of the State of Missouri which provide that candidates
may not be dismissed without specified cause after the first year. (In
general, I have asked physicians who join the staff to do so on a two
year

-

trial basis).

Sincerely yours,
Max
Mf‘mw

eno.

Pirﬂc,

Director

M. D.

�</text>
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                    <text>m
Mr.

Jam

D.

Paulus,

30,

1960,

Jr.

Chief of Flemming ami Cormtructicm
101 E. Capitol Avenue

Jefferson City. meswri
Attention: Hr. Stanley

her Mr.

Damler

Paulue:

Emloeed is a copy of a letter which I received thie
naming from Mr. True Steffemegen, the engineer in
the Division Of Research Facilities and Resources,
regarding our West Wing laboratories. I would be
you wmld check the proposed contract
wteful ifconform
with the requirements in this
so that it

letter.

Ihmk you for your cooperation.

Simmly yours ,
wax

Fink,

Director

w/jb

M. D.

�</text>
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                  <elementText elementTextId="105712">
                    <text>December 27, 1968

Dr. E.S. Paykel
Yale University School of Medicine
New

Haven. Connecticut

Dear Dr. Paykel,

I have recently read the report 'Trial of Imipramine
Patients' with considerable interest.
In re«read1ng the retort, I eannot find the data of the clinical response
of the subjects, 1.e., t*teets for the poat~pae drug conditions
for the behavieral measures. Table III indicatea that the differences
between drugs were not aignifiaant-~ but did the drugs affect the
clinical symptoms in the dosages given?
and Chlorpromazina 1n Depressed

appeared elsewhere, and if so, I
the tables. It may be that tha
the drugs or the sub—groups may
clinical change. partially related
to the dosages of chlorpromazine and imipramine selected; dosages
which you indicate are much lower than our own.

this ﬁata has
grateful far a copy of
lack of differentiation between
have haen the result of limitad

would be

Perhaps

It was a pleasure to read the report, and I look ﬁctward
to hearing of equally interesting studies from New ﬁaven.
Sincerely yours.
Fink, M.D.
Professor of ?sychiatry

Max

mil

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                    <text>May ‘26,

1969

Dr. Bug-m 8. PW].
Assistant Professor

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                    <text>November u , 196%

Dr. Henry Pechetein, Editor
Nassau D. 8. Newsletter

Hilton Avenue
Herpetead. New York
230

Deer Hairy:

It was

I regret

indeed a pleasure to receive your letter and
very nmch if I new: missed any copies of the

Newsletter.

My

address

is:

Missouri Institute of Psychiatry
SHOO Arsenal Street
St. Louis, Missouri 63139

It has been two years since I left Nassau oomty,
and only recently have the burdens of ackninistration lightened sufficiently to permit 1m the lmmries of looking abmt
and entertaining individual research. I was given 100 .000
square feet of space in a nw building, a small budget,

and the total support of the division director. With this.
to establish a major research and training center
in the sickest. wring these two years, the staff has
so that no»: we have nine scientists. menty technical
personnel and a staff of eighty to care for a patient population of me~hmdred meaty in our own wards. The
State budgets. inadequate as they were at the beginning,

he hoped

W

have been supplemented by Public Health service funds so

that the Institution is now functiming on an armual basis
of a half million dollars. Host inportant, we have begun
to make observations which Hy associated and I think sufficiently iwortant to present to national and international

meetings.

It has been an exciting two years, and many of the
things which I wanted at Hillside I have been able to obtain here. We have our patient populations, and the
privilege of emitting patients from mywhere in the State.
The wm are new. aimditioned and the room are spacious.
We have no problem of over—crowding, since adnissim is by

�w'v

-2-

November

1+,

196*!

Dr. Henry Bechstein

seized/nu
invitation only. Since adaiesien, we have established
laboratories in electroencephalography, experimental

neurophysiology, pharmacolcy and experimental psychology.
have our own canputer center and medical library. Under
construction is an animal facility, and this unit has received support from the Federal Govemsent. With luck.
it, will be available on March 1, 1965.

We

There have been sane pmblens in the relationship
and the local Universities. The

Ween the Institute

Institute is the Depatment of Psychiatry of the University
of Missouri in St. Louis, effective this moth. The
University has a medical school in Colmxbie, which is in
the center of the state. The Ctmators contemplate the
develOpment of a new medical school in St. Louis by the end
of this chcade,and are already planning various departRents. This Institute is now the first department of
the new medical school.
When I came to St. Louis, I found no problem in the
relation between clinical psychology and psychiatry.

Clinical psychologists, with rare exception, are affiliated
with the Universities and if they promise, do so either
in conjunction with psychiatrists or to a limited extent.
Only in the last six mmths has the problem been raised
when the Missouri Psychological Association has broedued
the possibility of certification for psychologists in this
state. The city of St. Louis has two medical schools
and in addition there is a psychoanalytic foundation.
This is unaffiliated with either school but provides some
teaching for the students of both. It is a small group and
does not carry the weigh: or force, that similar bodice do
in New York. Perhaps this is one of the reasons why cline
ice]. psychology has not established a msj or foothold..

If my

I agree with

you

that Nassau needs a medical school.

figures are correct, Nassau cmmty has almost two
million inhabitants. Missowi, with four million has three
medical schools and there are two on the planning board.
I recently visited the mdical school in New Mexico, and
their school services a state with a populatim less than
half of Nassau county. If the politicians in Albany and

inthecomtywouldccme toagme, Ithink itwouldbevery
inportant to have a medical school in Nassau. and in Suffolk

�mm»:

"7er w...-m_n..

~3~

November u, 196%

Dr. Henry Pedastein

These would do mm, perhaps, than mother school in
Mmhattan Island.

Imiss allmyfriendsbaokﬁastverymhmdm
famd mating with them a pleasmt oxperienoe. Given
the opportunity, I would very much enjoy attemding

ﬂmfowoooasimothatlhaveoometoﬂueoity, Ihave

another mating of the Nassau 9.8. Flame extend my
best regards to all my many friends. Congratulations
your appointment as Editor. I hope you enjoy the po-

sition as and: as I did.
My

best pemoool regards.
Sincerely yours,
Hex

Fink,

Director

mf/ ls

M.D.

am

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                    <text>February 5, 1997
Henry Pechstein, MD.
145 Cathedral avenue
Hempstead, New York 11550-1125
Dear Henry,
What a lovely surprise! It was a pleasure to look through that Newsletter
of 1959 and to realize that it was almost 40 years ago. The names alone -- Lenzner, Nord,
Shapiro, Zuger, Bauer, Whittier, and the speakers Nate Klein and Harvey Tompkins-brought back images. I remember almost all of them. It was a much freer time in
psychiatry; our battles with the psychologists seem like the battles of Neanderthals today.
archives.

I am delighted that you are sending the old numbers to the Society

I am still teaching at Stony Brook. I have maintained an active research
interest, and seem to have made a name in keeping electroshock alive. My book in 1979
was useful; my student Richard Abrams took it over in 1988 and is now issuing his third
edition. Not to compete with him, I decided that a ‘popular’ book on electroshock was
needed and I have just signed a contract with Oxford University Press for a ‘trade’ [read=
popular] book which I hope to have done by June.

All in all, life has been good to me. I trust the same for you. My thanks for

thinking of me.

Sincerely yours,
Max Fink, M.D.

�</text>
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3, 1985

Dr. Robert E. Fed:
230 Hilton

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Wand, MYork

Mach:
Immrymdxsmpﬂudbymintnmﬁngmimin
the new: issue of thJamaal cg

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                    <text>"pp--

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rm...

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~,«

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vm.

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Mom
Congress Department

Miss T.

1967

'

Excerpta Medina Foundation

119-123 Hemngraeht
Amsterdm, The Netherlands

Dear Miss Peereboan:

.I have reeeiveda letterof inquiryfmnmyformroo—
worker, Dr. Turen
of the University of Missouri, requesting
infomtion regarding his report the “Treatment of Chronic
Psychotic Patients with Canbimd Medications" which was pane»
seated at the 1966 meeting of the CINP. In your response to

Itil

his Question, you ”indicate that this report was read as part
of Smosiun VI of the CINP'.
This is imorreot. Symposium VI was dedicated to anticholinergic medwnim in man and animala, and mother
presentation by Dr. 11:11 was invited for that swipesimn.
It was lamented in abstract in the Symposim VI abstracte;
and is includdd in the Eleevier volmne.‘ The report cited
‘

above was read aspen of free mutations. and is not
being published in the special volume dedicated to the
anticholinergic problem.

more,

If at all possible,
consideration ohould be
given to include the
of the enclosed report
“'I‘reatnent of Chrmic Psycl'wtic Patients with Contained
Medioatims“ in the Proceedings of the CINP, as published
by
Media, as it is? not germane to the volmm I
m preparing through Elsevier.

mletetm

15er

Thank you

'

.

for your consideration.
Sincerely yours ,

err-x

Fink, M.D.
Professor of Psychiatry

Mm:

awn

'
CKY‘TJ'

WW1;

.m-

Mfzkp

u
“

wrwweya-r'pw

:r'a

im‘;

"mule

831C:

.

�</text>
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                    <text>May

Miss T. Peereboan

Games

1, 1967

-

Department
Ebcoerpta Medical Foundation
119-123 Herengmcht
Amsterdam The Netherlands

‘

Dear Miss Peer-shoots:

molosed are the galley proofs for the Symposium VI
"Anticholinergio Drugs and Brain Function in Animals and

Man"whioharetobepublishedaspartoftheroeedings
of the Vth International Congress of the GIMP. I have reviewedthesequencyofpapersandmuldmmndthat
.

they be published in the order in which they are sent to
you, notably, the inuoduotory statement; followed by the
papers by Bradley, Longs, Domino, Itil, Pink and Itil,
Carlton, Bursa, Hers, White and Rudolph, Cumlio, Boat
and
“iiimioh, Votava at wt. , Votjeohovsky' et a8. and Vitek

st

.

I

have reread the introductory few

lines and

am

taking the liberty of enclosing a better smmary of the
full symposium. If it is possible
to publish these few
paragraphs, I believe they will enhance the symposium
ixmeasmebly.
Separately, I lave returned the absuact for my
presentation in this symposium with a request for reprints.
Perhaps, if the full abstracts of this symposium are
published together, it may be possible for the printer
to

moffamallnmnberofalltheabstrectsinaoover.
This would be
a valuable

manento for the participants
to pay for such a reprint.
Thank you for we opportmity of seeing these
Incidentally, I have written to Dr. Domino answering proofs.
his
question directly.

and

I

would be pleased

Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>i.”

:

t

'1‘

&gt;-

'. r

M

MNMWL‘W
;)
F.

Q:

:3
5},» iffﬂ/‘ivavwi

Nowher- 2. 1963

Hr. H. E. Pellegxdno
Person-ml 91mm

man}. Hospital
5mm
3.700 NM.
Miami 35.

Dear Mr.

10mm
Haida

190113311119:

Pimemptwmmfwmmngmhtter
ammbutlhadmnmyfmnyaffioe.
1963
EEG

to

Miss Walton was mloyed
October 28, 1963. liming

Labomtczy.
She

at this Institute fmn. July 15
this time. aha worked in the ,

proficiency in naming.
mutated good taduﬁaal
in making with otrmr members

and was most friendly and cooperative

of the staff.

wanted

She
an ability to use an Offner D—3 eight
(mam). immanent, as well
to make special ﬁxeasmmnta using
mr specialized elwtmnic fraquancy analyzer oguimmt.

W

relations to patients were good. and she abound eonof paydziatric patients.
judmt in the

Her

sidcmble

a

She left this imtitutim fem personal masms mRamist.Ishwldlikotommndhwfwapositimofﬁﬁs
inted to her wings.

Sincerely
Max

)1me

Fink,

Director

yam ,
H. D.

_

�</text>
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                    <text>April 16,

19634

Dr. 3. Ponick

Psychomwmmlogy Serﬁoa Center
National Bank Euilding
692.7

Arlingtm

Road

89W 14, Maryland
Dear Dr. Penick“:
As you zequassted, I have mviewed the application
of Dr. Sugemzan. I 356 no aifficulty with thia application

and do not balieve a

site visit is mowsary.

Sincerely yours ,
Max

Firm,

Director

M.

D.

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                    <text>August 13 . l969
Dr. H. Penin

Univ.-Nervenklinik
Bonn, Germany

Dear Dr. Penin:
We are planning a get together in New York after the
International EEG meeting of investigators interested in
EEG and psychiatry. Dr. Kunkel has suggested your name
A formal letter of invitation is attached.
as a participant.

I look forward to meeting you in our laboratories on
September 25. l969.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

NF:kp

�</text>
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                    <text>Ocﬁdber 30th. 1972

J. Kittin Peary,
national Institute of Health,
Dr.

E.I.N.D.B.,

Bethesda, unryland anolh.

‘Deur Doctor Peary,

Following the presentations at the Amarican EEG Society,
I diucussed the chromatographic arug tinny! with Dr.
Gallagher. Ho—susgcotod ynu may be sponsoring a symposium
in Haw York in December, presumably in conjunction vith the

AREMD

maetings.

If so. and 1f the session: may be open. I vmuld
appreciate a program and the details or participation.
many

thanks.
Sincerely yours,

ﬂux Fink, M.D.

Profasaor of Psychiatry

MF/ij

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                    <text>War

15 , 1963

Dr. B. Porcine

Old Oak Cottage
(11mm

Ham

Rim, Sam

England

Dear Dr. Pereirm

I am writing at the sugmtion of Dr. H. Lantin, who has
applied for a position at the Missmri Instituta of Paydxiatzy. Dr.
untinhaoindiontodﬂuthawwldliketomtomsmo for
additional
cxpcrimoe. ibis facility is a resent-oh cantear with ham emphasis on clinical psychiatric research. In waking
here, In. Lantinwiubompmaibhfaamllblodcofpatimta,
most of whom suffer with a major paydmosia.
I would be grateful for your momnéntion regarding Dr.
Lmtin, his personality, his ability as a mg psychiatrist and

Wn

wwumtuusmhismnﬁuforwthasamsoimt.
Sim-only yours .
Max

Fink,

Director

H. D
‘

�</text>
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                    <text>March 2, 1966

Press, Limited

M4431 23.81:

Long

mm:
in

Strut New

Island City,

,

York 11101

W8mutation of digital
Wears.
Want
01' the speeific applicatims those to

the quantitative analysis of

in glam-deal signals

mm has become an

amputee? mthnds

electrmncephalo

effort has

gone

.

hy have

Special
hem of evoked

the averaging of

-‘

,

m

interest.
potentials and my
electronic mthods of

axmllnnt reports have been written. The
analysis haw recently been
by a popular review
written by two Soviet authors and distributed in translatim

mixed

Wt
Wrmummmmcfdmgesinﬁeqmncy,
of Gamma.

by “me

pattum

resulting from anesthesia, drugs, sleep, etc.
The» laboratories have dowlopdd “rims applicatims of
digital mthods fem time moses. We have mum man-y m~
quests formpmgm whavebunmgedmsmmﬂze this
infmtim in a mammal manual. We believe that than is
medforsudxatcdmimlmmmbemHnmgememlly
available and am sending it to you for yam maidamtion
for
publicatim. I: this interests you, wa would be pleased to
discuss mmimtims and modifications that may be
many
and smut-21¢:

to provide a

m gunemny applicable

docmmmt .

Mmmmmidamim.

Simlyym,

Max

Fink. NJ).

meess’w of Psychiam

{wig—4.

.&lt;_

1:11-5:51.

twimtzinw-w‘

mu—

war

'

1511‘“

WM"

mem‘!‘

�</text>
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                    <text>April 11,
Pergamon Press

Elmsford,

New

1970

York

Gentlemen:

Kindly enter a continuing subscription to the
Journal of’Esychiatric Research, effective with the Januari,
1970 issue, addressed to:
Fink, M.D.
Department of Psychiatry
New York Medical College
5 East 102 Street
Max

New

I would also ask that the
sent.

York 10029.

1969 volume,

if still available,

be

If I understand the instructions correctly, this
subscription will be at the annual rate of $10., since we are

already subscribing as a Department throgh our library at
Metropolitan Heapital.
and

as

bill

Please make the subscription rehewable until cancelled
us annually.

billed.

The 1969-1970

subscriptions will

be paid as soon

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

mf/

�</text>
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Pmss Ltd.

MQ-Ol- 2181:
Long Island

SW‘t
City,

New

York 111.01

Gentleman:
For

my

personal use only and not for loan or resale,

I would like to

stibetto the fonwing mo journals:

Joumal of Psydniatric Research
Journal of Psydlosomtic Resaamh
Sincamly yours ,
Fink, M. D.
Emcutive Director
Max

�</text>
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Ber-gamma

awn

bang

196’4

Press Ltd.

215:

Street

Island City. New

ma 11101

Gentlemen:
V

returning yam insoiee no. N! sue/10 covering
me year swem'iptim tn the mammal of Psydxiatric

I

am

mm?
93ch
Mmomemdinm,md1wishtocm1tm

Research“. and “Jamaal‘of

éwpsm.

53.1160le yams ,
Mex

m,

‘

M. D.

Bucutive Dimctor

�</text>
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                    <text>July 14 , 1970
Dr. Marvin Perkins

Chairman, Planning Committee
Third National Conference Methadone Treatment
National Association for the Prevention of
Addiction to Narcotics
250 West 57th Street
York, New York 10019

New

Dear Dr. Perkins:
Dr. Freedman has left for his holidays, but before leaving,
asked that I communicate our suggestions for the Third Methadone
Treatment program.

duration of action and means of extending methadone's
useful topic. Comparisons with other treatments,
the
narcotic antagonists, would provide an appropriate
particularly
Tho data on
may be a

action

contrast.

Sincerely yours,
Fink, M.D.
Professor of ?sychiatry
Max

Mszt

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                    <text>March 19, 1962
Dr. Seymour

Perlin

Department of Psychiatry

Montefiore Hospital
&amp; Bainbridge Ave.

E. Gun Hill Rd.
Bronx, N.Y.
Deer 8y:

pleased to write this letter on behalf of
I have known during the past three
During this time I have
Hillside
Hospital.
at
years
been his supervisor in research duﬁ.ng his residency;
and a co—worker in the somatic therapy program of the
I

am

Dr. Lefkowits, whom

hospital.

Dr. Lefkowits is s sincere, thorough, and responsible
As a resident he stood above his class in his

worker.

research interests and his willingness to accept respona
sibility. As a consequence of his excellent record, he
was promoted to the position of junior psychiatrist and
assigned new residents for supervision as soon as his
resident period was ended.
During that period he also undertook a study of the
milieu influences on selection of treatment at our hospital.
He showed considerable ingenuity in this study, and the
published in the JOnrnal of the Hillside
report was recently
He
was
an active participant in the research
also
Hospital.
seminars of the hospital.
Lest fall, this Department instituted e psychophernecologic after-care clinic. Dr. Lefkowits was put in charge,
and his
excellent ﬁudgnent in the management of the
shawn the unit
units
‘~
wa:nit was a deficit tperstion/
e.‘
the”H§HT€ET“Biructvr decided to discontinue the clinic.
‘

;é

15%...ng

”$3M

,

.

�It is

my

impression that his idontificstion with psycho-

pharmacology

:

:

;ww,

I

decision to leave Hillside.
Dr. Lefkowits

is

‘

;

._:

M;

in the

To

WW”

capable young descriptive
training and a good grasp of
somatic therapies. He gets along well with patients
and
with his peers. He is methodical, occasionally cver~
meticulous, serious, and friendly. I have no hesitation
in recommending him to you for a
within his
abilities ~ for he will serve the position
institution well.

psychiatrist.

He

a

has good

Sincerely yours,
upsgp

Max

Fink,

M.D.

�</text>
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                  <elementText elementTextId="103231">
                    <text>”v»:-‘.-w»«;.u-..-g

”mnt'n‘:

any!

(«mu-‘WWW v...

.

—w0'ﬁm”'—m wwwmmwmscmxw

-,~

‘

or.

Mow

ﬁnnnuol Parlnuttor
York limos

m

3a.

1979

new York, Ron York

Door

ﬁr. Porlauttor,

Your article reporting acoroooototlvo attlogor'a plan to
introduce a bill “. . . to Fight Youth Addiction” (av? 3/29, pg. 61)
is misleading in associating ruporto of‘horoln and unsuish under a
single addiction hoaoing. Tho rtuort doocribos a program to control
heroin adalotiou; includes, without o.brook, a roport on arroats for
hashlsh; and concludes with c tooort of two docths ascribed to heroin

ovordocago.

Tho sanéwlchlng of hsohlih botwuoo two atories of heroin undo:
a single addiction title associatos two alsparoto drugs under coo
opprohrlous title, and is not up to tho yroﬁhsaod standards of the
Row

York

limos.

l. Hashish is not horoin, is not an opiate, ls not dopendenco
producing, and has distinct pharmacology, chooistry and offbcts on
tissue: (ruforonccs may be supplioé). one could oaks as good a
caso for associating ethyl alcohol god oulatos, as cannabis and opiates.
2.

There is no proven biological tssocintiou between the two

drugs. All associations are legal and social.

3. The confusion ongondoroé by equating the two drug classos
oncourngos mlslntorprotatloua by the goblin. Lawyers weaponsible
for low: equate cannabla and opiates (sou the omnibus urug Bill

Earljuano users are rooortod to try horoln
of addiction when marijuono importation is
risks
attending
its
curtailed. Criminal gonoltloo for too abusa of‘tho two drugs or.
often confusod.

gauged by the $onoto).

with

sincerely yours.
us; Fink, ﬁ.5.

Professor of Psychiatry

2%?

:kp

bcc:

A. O.

Sulzborger

be encouraged to review the differences
in drugs with some scientists. I imagine a seiinar in clinical
pharmacology would be useful. It can be arranged.
Your

staff

may

�</text>
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                    <text>January 28, 1996
Dr. Lawrence C. Perlmutter

Department of Psychology
Finch University of the Health Sciences
3333 Green Bay Road
North Chicago, IL 60064-3095
Dear Dr. Perlmutter,
Dr. Avi Calev has been a neuropsychologist in our program since 1990, and has
asked me to write a letter on his behalf. I have known Avi for about a decade, ﬁrst becoming
acquainted with him through his work with Dr. Bernard Lerer at the Hebrew University in
Jerusalem. At the time, Dr. Lerer was studying the electroshock process, and Avi provided most
useful examinations focused on cognition. With Dr. Lerer’s encouragement, he applied and was
appointed in our Department as a member of our electroshock evaluation program. He was well
liked and when an opening appeared in the inpatient clinical services, he was appointed as the
psychologist of my inpatient team. My relationship with Avi is therefore at multiple levels -- as a
co-worker, supervisor, and friend.
Avi is a talented neuropsychologist with an excellent grasp of psychometrics,
projective testing, statistics, and experimental design. He has been an active co-worker and a
leader for various projects, as attested to in his curriculum vitae, where he has a large range of coworkers. In addition to the reports of the cognitive effects of ECT, he has also assumed
responsibility for studies to determine whether pre-treatment with caffeine will inﬂuence
therapeutic results and cognitive effects of ECT. He has already published the preliminary results
which argue that the effects are favorable and is now completing the data collection for a random
assignment study.
I have known him also as the team neuropsychologist on our inpatient service. As
he
has
been most helpﬁil in assessing patient characteristics, elaborating the techniques for
such,
our residents and medical students, and assuming responsibility for psychotherapy in selected
patients. In the latter instance, he both treated patients and supervised our residents.

�Lately, he developed a relationship with Dr. Lynn DeLisi, an expert in the study of
schizophrenia. Together, they are working on a number of projects with which I am not directly
acquainted.
Avi is a conscientious, interested, intelligent, and well trained psychologist. He is
well liked by his co-workers and I have been delighted to work with him. He is knowledgable
about the literature, is able to document his positions in argument, and is technically skilled. I am
distressed that he has been asked to leave -- a situation which has been occasioned by the
necessary down-sizing of our Department and not associated with any of his defects or actions.

Sincerely yours,

Max Fink, MD.
Professor of Psychiatry &amp; Neurology
Attending Psychiatrist, University Hospital

�</text>
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                    <text>May

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back issues of Egilegsy

Abstracts, Vol.

I. (if available)

Abstracts, Vol. 11.

Name

Address

_w_

Organization __

�v
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up,

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-

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v-VIIW»-.~zarln4.

---.

September 22, 1969
Dr.

J. Kiffin Perry

KINDS, HIE

Bethesda, Haryland

Dear Dr. Perry,

anr exhibit of a citation and abstract search for
epilepsy abatraota at the International EEG meetings in San Diego
was moat intereating. The aearoh worked well and the available
data base will be neat useful.
Some yearn ago, at the Hiaeouri Institute of Paychiatry,
aaeociatee and I developed a aieilar ayaten for the IBM 1710 for the
apecific aubjecta of EEG and Huean Psychopharamoology. we elected to
one citationa and uniterma, and after one year's experience found that
the abatract or auenary wee preferable to the unitere or the QWIC
index nethoda. Funds, however, were not available, and we abandoned
the project.

my

exciting.

make nee

The

and the data base it most
what conditiona we may

availability of your system

I an writing to enquire under

of the system.

we

have an

IBM

360/AO

at the College with

terninala as well as aome apecialized acope terminals.
computer center in dedicated to the servicing of the profesaionnle of

the usual

Our

and

13M

the College, including the Departmenta of Neurology and Paychiatry—for when your data bane may be useful. In there any provision for
our application for the use of your ayatem 2

In there any provision for the extension of your data baae
to include other abstracts of NIH, such as Paychepharmacology Abstracts
of NINE 2
Thank you

for your cooperation,

the success of your project.

and our

best wishes for

Sincerely youra.
Max

Fink, M.D.

Professor of Psychiatry

of]

Chairman, Computer Counittee

�</text>
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                    <text>h

&lt;:l$&gt;

July 16,

1979

Dr. Candace B. Pert

Clinical Center,

Bethesda,

MD

Dear Dr.

Pert,
I

NIMH

20205

embarrassed that other committments kept me from
my associates were kind enough to keep notes and
me. I have sent your expensesvouchers to the
administrative assistant, Mr. Vacnon, and you will be reimbtrsed
am

your lecture, but
shared these with

in

due course.

Our studies of des—Tyr-ypendorphin are on 'Hold', pending
re-assessment of the pharmacologic data. The material prepared by the
chemists in Holland meets all the chemical standards for purity, but
has not shown the pharmacologic activity claimed in the initial samples.
Our studies will wait on the re-assessment and possibly another batch
production. Perhaps these experiences are a caution to the workers
in this field, that chemical purity may not be a guarantee of
pharmacologic equivalence.
him

Have you thought of writing to Dr. David de Wied and asking
for samples of his original material to test in your test systems ?

I trust we will meet on another occasion, and have the
opportunity to discuss this exciting work.
My

regards.
Sincerely yours,

Anal“

th Fink, M.D.

‘WW‘WMLVWJ

‘v'a

*LWJV.

A

4

{MM

know if my associate showed you the book on ECT that
I published earlier this year. I took a flyer in that work to
suggest that the mode of action of convulsive therapy was bound up in
its liberation and stimulation of brain peptides with behavioral
effects. I emphasized the experiences with TRH and ACTH more than
with the endorphins, however.

P.S..I don't

�«we. .m-n—

wiwvwv-m—v-

W~wwmw~v~v~w

..._,.

v”

a,..,.-.rm.._....-....._.-.w—~-w

.._

May

.1

~_

1*.

,— “H...”

1979

Candice Pert, Ph.D.

NIH

Bethesda, Maryland
Dear Dr.

Pert,

It was kind of you to accept our invitation, and I
look forward to your visit on June 25. Separately, you will receive
a formal invitation and details regarding the arrangements for your
lecture. I am writing to give you some background to our present
needs and our wishes for your contribution to our program.
The Long Island Research Institute is the youngest and
smallest of the three research institutes in mental health in New
York, having been established three years ago. Many members of the
staff are involved in research efforts which had their origins in the
enthusiasms of the past two decades. The Division Directors have
recognized the nature of these ifforts, and seek to broaden the ex—
perience of the staff. One of the issues which has been prominent this
year, is that of the developments in psychoneuroendocrinology. In this
regard, we have invited Peter Stokes, Arthur Prange, Bernard Carroll to

lecture to our staff.

Both Dr. Harvey Karten and I have been interested in
studies of the effects of peptides on behavior and we are interested
in your experiences and the development of the concepts underlying

the activity of endorphinsﬁ:opiate receptoss with their possible
effects on behavior. No work of this kind is in progress at this
time. The closest is our EEG studies of ACTH fragments and the studies
of des-Tyr—f-endorphin which will begin in the next few weeks.
we would be delighted to have you describe your present
theories. It would be particularly helpful if you could help
us see this work in the context of the developing science.

work and

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

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                    <text>Directions in Psychopharmacology
Published by
The Hatherleigh Company, Ltd.
420 East513t Street
New York NY 10022-8095

EDITORIAL BOARD RESPONSE FORM

Name Max Fink, MD

IE

I

D

In addition, I would like to write a lesson on:

would like to serve on the Program Advisory Board of Directions in Psychopharmacology.
h

/2
'

W
AIM!

I]

A deadline of

El

Thank you for the invitation to serve on the Board, but I must decline at this time.

JW

Signature

is requested for my manuscript.

(576

)

4¢¢~2¢90

Telephone number

//F/»\//¢ @ 579.5001. swysa.

(5/4

)

£42—

FAXnumber

(604!

EZML

e-mail address

Please indicate any address correction here:

de 60X

[IA/K, HUA-

70.
57.

‘70.”,

6/5?
My

xx/rowe/s?

Please return this form, along with an updated curriculum vitae, and send to:
Steven L. Pessagno
Managing Editor
The Hatherleigh Company
420 East 51 Street
New York NY 10022-8095

Thank you for your time in completing this form.

�</text>
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                    <text>rum-er ‘1‘i.Imu-L':,"‘my"‘i"ﬁ1.uwr‘wf1“'fl|‘.o-~SrIIr-‘jr'‘

V

7

,

.

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~1Hv"w¢mmwurwp“~ﬁ‘yvl-.—

t

“(Wyn——

‘

September 9. 1969
Dr. R. Peterson

National

Institute of

5454 Hisconsin

Chevy Chase.

Mental Health

haryland

Dear Bob.
I am writing with regard to a proposed grant - contract
to develop a delayed release implantable naioxone.

Following our original discussions with Dow~Corning.
the makers of silastic, we contacted the Food and Drug Research
Laboratories, Inc., as a local concern with experience in the
development of delayed release compounds. After an interchange
of letters and discussions they submitted a proposal dated
August 22. The program follows our request and we believe
that such a program has public health merit. Their budget.
however. is reasonable for direct costs, but unth the over—
head. appears larger than the contract amounts which were
discussed with Drs. Cohen and Miller in June.

are aware that NIMH is supporting a contract with
at the University of Delaware. Considering the
magnitude of the drug addiction problem and the logic of an
implantable antagonist, we would like very much to recommend
the additional program in New York. If an implantable naloxone
could be produced, we would like to do the clinical assays.
we

Dr. Yolles

I am

writing to ask the best route to obtain

of this request.

The

possibilities are

through the
l) Contract
HYHC
(With

2)

overhead?)

many

a review

including:

hen York Medical College.

Contract with an individual. Dr.
(no overhead).

A. M. Freedman

-

(4.

.

3) Grant application (as a grant

like to

we

would probably

this program to include our
for
clinica
trial as well.
expenses
expand

N'.~w=r‘v:g' ovum—m

,

q-

2”“; w w'm.w1

3:”

my

�Dr. Peterson

-2-

Septenbor 9, l969

Since we are not the primary contractor. what do we do

frist trial of

nine months is unsuccessful?

I would be

reached

at (212)

grateful for your recomndations
or 369-8488.

369-7900 Ext. 246

Max Fink. NJ).
Professor of Psychiatry

GHC.

the

and can be

Sincerely yours .

MF:kp

if

�</text>
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                    <text>January 7, 1970
Grass Instrument Co.
101 Old Colony Road

Quincy, Massachusetts
Dear Bob,

In order to provide for the play-back of some of our tapes
need, as soon as practicable, another Model 79 portable polygraph 9
particularly the chart drive, regulated power supply, oscillograph,(1),
I

and

signal marker.

I already own

For

a 7P5118.

until this

can be supplied.

me an approximate delivery date by phone.
come through the International Association.

checking and giving

The order
Many

will

thanks.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
.v

.r—ynr

amplifier should be

this purpose, I would be willing to Obtain a used
if such is available. I would appreciate your

instrument

--

A-

The

I need this instrument as soon as practicable and if it can
be supplied sooner without the 7PSll, I can use one of the many

e—r

..-

Peterson

Mr. Robert

MF:kp

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                    <text>August 20, 1970
Mr. Robert

Petersen

Grass Instrument Co.
101 Old Colony Road

Quincy, Massachusetts
Dear Mr. Petersen:
one Grass Mechanical Timer, Model MT7A,
Serial No. 70208. We would appreciate your having it
repaired and billing me at the above address.

Enclosed

is

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kt

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                    <text>'-."='w-1V)‘1¢1Wb"vﬁTtym'mzn

m

vw

sf. -.'-. r». way»

»

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VVL~Ww-rv-r—vl-~“3I—me a-yrmnn

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W...

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February 10 , 1971

7.wa

..._

Dr. Robert Petersen
National Institute of Mental Health
5454 Wisconsin
Chevy Chase, Maryland 20015

Dear Bob,

I spoke to Dr. Allen Isin of Bulfalo at length today, and
found him knowledgeable about polymers, release rates, hydrogels,
etc. He offered to assist us in determining the release rates of
out antagonists in his polymers.
I

was impressed and we

agreed:

n.

(1)

‘

"Farr-4's

.

some
.
nam‘

He

I would review these with the chemists and send him
cyclazocine and naloxone;
We

their consultant.
in

literature about his processes;

(2)

(3)

'a1-2'1'mwzr

would send us some

Many

a long
My

(out chemists) would call Dr. Kenneth O’Driscoll,

thanks for the

referral. I

acting antagonist.

hope we can get some progress

best.

7w"w:ww:;vtﬁww'mj.~wﬁ'i=u

Sincerely yours,
u'gzvmmm

Fink, M.D.
Professor of Psychiatry

Max
,,,,

V"

A:

MF:kt

cc:

A. M. Freedman, M.D.

.

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�</text>
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9

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zr-v

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~-,—

w—m‘ :rv‘ﬁwt'ﬂ‘r Milt-run :r.

wmm-wm

m—w-.rv_m.wwum

‘Wmnn-VW;

March 22, 1971
my”

”up"

ml~n&lt;1uww~

..—~w«nv..p

Dr. Robert Petersen

National Institute of Rental Health
5454 Wisconsin
Chevy Chase, Maryland 20015
Dear Bob,
had the need to refer to
the
report, "marijuana and.Eealth", and on each occasion found
concise, balanced and apparently complete. You and your associates
are to be congratulated on a fine, basic document - one which deserves
a wide distribution to scientists and students.

During the past few weeks,

it

HEW

Many

I have

thanks for making the capias available to us.

Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

MF:kt

..

r

z

w

1:,

-.

-9 ;

-

�</text>
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                    <text>g

h
g
L

March 5, 1971

Dr. Robert Petersen

Chief, Center for Studies of Narcotics
5454 wisconsin Avenue

Chevy Chase ,

8 Drug

Abuse

ﬁeryland

Dear Bob,

I am writing to bring you up to date
contract study of cannabis use in Athens.

on the

status of the

Following the renegotiation of the contract terms in the
designed the data collection phases of the study, made up the
necessary forms, and scheduled the initial data collection for March.
After sending the outline to Dr. Castes Stefania, we received no
reply for many weeks.

fall,

we

February 20, he wrote: " I wish to apologize for the
long delay in answering you. This delay is due to the fact that a new
law on narcotics has been passed and is in effects since January 10,
and all this time I have been trying to find out whether under these
On

restrictions,

any

investigation

on hashish, which

is included in this
is a very serious

law, could be carried out. This, as you understand,
problem . . ."

Dr. Stefanie concluded his letter with some suggested steps
he had undertaken to clarify the issue, and indicated that
we would be " . . . hearing from me within the next few days."

that

We

have

not, as yet, transferred

any funds for the

project,

Under these circumstances, we have no recourse but to await
a more favorable reply. Unless, there is an alternate population
in which the study could be undertaken.

I will keep you informed.

g

l
.

Sincerely yours,
Max

Fink, M.D.

Professor of Fsychiatry

�</text>
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                    <text>“w,

«arm—MW‘u—wvsv-

—~

nu.-..,..r..t.g—v—

.r

.

wv—.-— p

7”...— iv...- mw—wn-wvn—wmww—uu—w—u—u ~.w—.—...v~.,.»..._..m~~_-—nv—w

w.

—

fr...»

'I‘-«_-'- .

—-

&gt;~\W;L'ﬂn.m—«v-.. w... 3,...

n

v

,

. -~-

November 16, 1971

Dr. Robert C. Petersen

Center for Studies of Narcotic

&amp;

Drug Abuse

National Institute of Mental Health
5600 Fishers Lane
Rockville, ﬁaryland 20852
Dear Bob:

In response to your request, we are pleased to send this report and appendices, using as notations the numeric references of your

letter,

10/26/71.

With regard to the

last question,

we

have had unusual, and

to us, unnecessary delays in obtaining marijuana and THC. Our requests
require 3~4 months of processing, and in the 21 day study, the Committee's suggestions (interdictions?) as reported by Dr. oroude, were
not based on experience satisfactory to us. The delays resulted in a
loss of half our sample, who were available for study during the summer
only. Since research effort, if truly innovative, will be novel to the
Committee, it may not be possible to satisfy their anxieties, leading
to covert behavior on the part of investigators. Perhaps, investigators
who have passed the hurdles of institutional peer review, NIMH peer review, and

clinical

and research experience, warrant the same deference

to their judgment in regard to studies of cannabis is is accorded their
studies of other substances in the service of man. The present Commit—
tee or its spokesman seen to assume prerogatives not ordinarily accorded

advisory colnittaas. It would be a welcome breathe of moderation and
restraint for the Committee and 31MB authorities to exercise less demanding control over the minute details of experiments and experimenters
with regard to a drug as extensively studied as cannabis.
make

Should any additional data be required,

than available.

we

will

Sincerely yours,
Max

Fink, H.D.

Professor of Psychiatry

HF:ig
Enc.

he

slid to

~.

�</text>
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                    <text>November 2, l97l

E

Dr. Robert Petersen
Natlonal lnstltute of Mental Health

Rockvllle, Maryland

l

Dear Bob,
am pleased to enclose our appllcatlon for an
extension of the studles of chronlc cannabis users to a populatlon
ln Jamalca. The study, Physiological Effects of'Chronio cannabis use
in Male Jamaicans, ls planned to progress ln parallel wlth the
Greek study.
I

A copy of this proposal has been sent to Mr. R. J. Gradwell
of the Contracts Management Branch and to Dr. Bunney.
My thanks for your recommendatlon, and for the
opportunlty to conslder thls lnterestlng study.

Slncerely yours,
Flnk, M.D.
Executlve Dlrector

Max

"HI-WW

‘

.

,
.
.

'5-H’

�</text>
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                    <text>February 11, 1972

Dr. Robert Petersen
Division of Narcotic Drug Abuse
National Institute of Mental Health
5600 Fishers Lane

hockvi lle , .i'aryl and

20 852

near Bob:
Enclosed are the two revised budgets, for the Jamaica

and Greek study programs.

Separately we will send the detailed progress report and
protocol for the Greek study, probably within the next 10~15 days.
For the Jamaica study, we are unable to relate our proposal
we will accommodate
to the prior study without your help. With

it,

the social aSpects to the data of the prior study.
Many

thanks for yourttime.

Sincerely yours,
MEX

Fink ,

2‘. D a

Professor of Psychiatry

HF:ig
Eﬂc.

�</text>
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                    <text>February 11, 1972

Dr. Robert Petersen

Division of Narcotic Drug Abuse
National Institute of Mental Health
5600 Fishers Lane
Rockville, Maryland 20852
Dear Bob:

Enclosed are the two revised budgets, for the Jamaica

and Greek study prOgrams.

Separately we will send the detailed progress report and
protocol for the Greek study, probably within the next 10-15 days.
For the Jamaica study, we are unable to relate our proposal
to the prior study without your help. With it, we will accommodate
the social aspects to the data of the prior study.
Many

thanks for yourttime.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Ming
Bic.

�</text>
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                    <text>Hovaubor 30th, 1972

Hubert Petersen, Ph.D..
Division at Narcotic and Drug Abuse,
ﬁatiennl Institute of Mhntal Kealth,
5600 Fishers Lane.

Bockville. Maryland 20852.
Dear 30b,
1

:3 enclosing copies of all tha correspondence

(some af.whieh you may already harm) received tram Dr.
Beaubrun during an» lutt savoral weeks. The people in

Jamaica are vary interested in pursuing the praposcd studies
of canndbia and havu gone to the trouble of tracklng down
the possible naurces of misunderstanding and clarifying
any questionable issues about thnae studies.

It'vould seen.tha$ this correspondenae might answar
that Hashington has and it would be in
overyono's best interest to reconsider the studies at

any concerns

chronia ganja user: in Jnmni¢a.

These atudiea are particularly relevant as parallels
to the experimental data currently balnz collected on

chronic hashinh users in Greece.

Sinceroly yours,

MF/ié

Ens.

�</text>
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                    <text>autumn-18-

o'f"

3...“.a

01“

‘
.--

K

§731-511I
a"

February

lat.

1973

ﬁdbert Patarscn, Fh.D.,
Division on Rareotia Addietian and Drug Abuse,
Rational Institute of Mental Health,
5600 Fisheru Lane,
Roakville, Maryland 20852.
Dear Doctor

Fetcrsan.

Enclosed is an interim report on the contract "$tudy of
Chronic Hashish Uaara 1n.Greace" (EEM h8~70~98), reflecting
obaervntions fbr the period Jnky 1, 1972 to Dacnwbar 31, 1972.
The report presents two aeta at data: a comparison of the index
ease. of hashiah users with a “contra." groupggand the abaarvntions
in the aubjectn smoking marijuana, haahiah and TKCwbw9 1n doaea
equ1Valent ta ?8 to 150 mg TRG~An9.

in our study of the hashiah users, «a found few deficits in
phyliology or test behavior whieh aould be prennmea to result
from tha use of hushiah (* tdbaceo). The comparison group. which
magma wall selected, shows the same degree of hast @ysfunctinn
on most

tests.

The

principal diffsrenaea batween groups are in

tests_of mnmory, a greater use a! tobaaco, and enlarged
palpable liver sages. These findings are an few as to lead to
the conclusion that users do not differ from controls. With
scan

regard to the

.

dbnarmalities, raported in 1969 which sparked
these stunias, the changes wars nat present in this aamyle of
users, nor eantrols.
In thn acute arms studios, twn 6bs¢rvationa stand out:
the subjects respond to vary high doses of different fbrmn of
canndbia; and that thare may be differences in their rasponae
unrelated ﬁo THCnA~9 content along. From the first dbaarvationa
V! are tmpresaad that talersnce to the neutral effects of
canndbin in wall established; an&amp; from the amenda that aomgonenta
of marijuana and hashish cther than TEC~A~9 are behaviarally
active, and that these activities ean.be parcellea out.
EEG

ﬁnal of the data, particularly the detached statistical
antxysea of the EEG, and EEGébehavioral correlaticns of the acute
expcrimnntn are in precasa. and should be comylete by march. To
that extent. the enclosad summaries are preliminary.

�derunry lat,

~e-

Rdbnrt Pateracn, Ph.D.

1973

Thu next quarter in dadicnted to these analyses; and to
the drug withdrxwal trislu. The laﬁter exparimants assume greater
significanno with the syntematio dbnervatian of tolerance ta
chronie hashish use.

In our 1972-73 request to undertake these stuaies. vo
proaoctaa a tins schedule or 18 months. Support for the studies
tar cue year was given with our mutual understanding that we fill
quatterly rayorts, and based.on the pmogreas reported in January,
the continued support woulﬂ be reviewed in February and Professor
Stefania and the Association unuld be aﬁvised by the and or
derunrx, whether the contract woul&amp; be extenaea beyona June 23,
1973 or terminated.
with

Our grograaa in
uhnm we have met

this study

has bean monitcred by Dr. ﬁgure,

Copenhagen in August, ﬂew York in
December, and Whahington in January. His

in

Hovember, ﬂan Juan in
reperta shauld sugplement thase notes“ In adﬂition, WE have
submitteé samples of hashish to Dr. Branda; ana in our next vitit
t0 Athena (early February) um 91am to bring additional aamples rbr
assay in 31MB contract laboratories.
We

trust these notea-are helpful.
Sincerely yours,

Mm»:

Fink ,

M. D .

ExecutiVE Dirmctor

cc.

Wk.

Bunney,

;.D..

ﬁIMH

a. Saara, M.D., HIMH
Eleanor Carroll, NINE

C. stefanis, M.D., Axhana
A: ”a
MODI’

MF/ij
Ema.

mm;

m

'

�</text>
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                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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        <src>http://exhibits.library.stonybrook.edu/mfp/files/original/e47873e96bb5f93f2bfa1211080cbb6d.pdf</src>
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                <elementTextContainer>
                  <elementText elementTextId="103696">
                    <text>‘5»;

ubvuubor 10th. 1972

a. Paternal. PM)”
new
Chief, Center for Btud1on of lureatic
Int1anal Institutn at Mtntai nunlth.
5600

and Drug Abuse,

richnrl Lane.

RattV1lle, lhrylnnd 20852.
Dear 36b,

£ur1nc the f1rnt three months of thc extended eontrunt
nau~h2~70~98. Study of aannnh1a “nor: in Greece. we hnvo

couplettd the tollaving port1ons of the progrin

Chron1a hnnh1lh 38!?! wire naked to thuntcer 1b: ftro
1.33103- ut‘vuekly intervnls. to snake hash1sh, unrijnnnn.
THC 1nmrbgntted pitcebo. and pltoebo.
Hashiuh was in two
dons, 3 an m. 2 m (equiv-.1.» to mo .3 and 159 mg
TKG~A*9). Hir1juan¢ rt: 3 an oqn1vulont to 75 as THCnAuQ.
228~A~9 Vll inprisnntod 160 as in tho plnoobot All cigtrottos
ware of 35 gm total vu1ght tan flllnr was tob‘aac, unproxinntely
k gm and tan renaindar l.I.M.H. placebo. During the first
turn. south: 12 nubaactu tangletod five sessions cash} (wt
have n1nce aunt add1t1ontl sapplica sad 8 more nubgoetn are
in procai- dur1ng Octobar and lovuuber).
Tbs EEG roeordn at tho fia't 12 aubjcata were pent to
us in nidoayytqdber 3nd their tnulytis has! been templetcd.
sine..thn study 1: onso1ag. thay are sending-u. the EEG

tapes as thcy aauplatl than. Vb anticipate the stutistieal
anulyiia should be done 1n December.
roport cauparins the saciul tad
haah1nh “law: u1th the first
group of control. « a cunnnry of which #31 sent in August ~
28 additional control: wort nurvoyud during thy summer. A
prol1n1nary annuity of that nut; 10 «nclosed, no presented
by Dr. Stcfunit and h1s eo~v¢rk¢ru to the 6.131.? uynpos1un
on ennnabit, held in Caponhsgen 1n mideugust.
relieving the

sun—try

nadictl ehnructor1st1cs at tha

Uh hnwu

had only can aer1oun

difficulty vhich vs: brought

attontian during thi past tow vuekt. Our protacol
roqu1r¢n us to bring tubaocts into tho hospitnl and have
than ntop Innk1nc 1n nrdsr to study ths withdrawal phnnaunnu.
Br. Stefania writes thst ha 13 f1ndins 1t difficult to motivate
to

IV

�Robert

ureter-en,

PM).

«2-

November

10th. 1912

the nan, and that thq funds allocated for doing so are
1n:deqnuto. Be doubts that any subgcct will rangin in the
hnlpital far that thcy untiaipate to ‘n extraordinnry
anxiatyaprovoting situ:tion for lean thnn 1,200 draehnns
($h0) P‘r day. ‘I an rovinvin¢.th13 prablan tad vill
approach Hr. Grndvell and youraolf within the next few
vodka with 3 specific auggaation;
Our present plgns are to provide t dctuiled analypil
the
bahuvioral, EEG. pnyuhological and othur physiological
at
mascara: in in: neat: pxpcrinantu or 20 subjects for our
quarterly raport dun on or nbout Jcnnnry 15th.
.

Siﬁcerdly fours.

Ml: Fink, M.D.

Iliad
Enc.

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                    <text>,5

«W».

ulvmwwu

ww—

«mu-m

,,-

October 26, 1957
Mr.

Petersm

Grass Instmxmnts
Quincy, Massachusetts 02169
Dear Mr. Peterson:

I an witing: with regard to your order J7~22-6 (our
order 10’4011). This order encanpasses two instnnxxems, an
eight channel polygraph and a four channel portable polygraph.
Please ship the eight enamel imatnmant with
associated equipmant to:

it!

‘

Dr. Max Fink

Departxmnt of Psychiatry
ﬁetropolitan fibspital
1907

Neva

First

York,

Avenue

New

Attention:

ka 10029

Mrs. C. Stubbs

For Roan 15A9, Ward 15

Please mark the crate clearly - that thia

Boan 15A9.”
The

is for

”Dr. Fink

,

portable polygraph is to be delivemd to:
Max

Fink,

M.D.

Depwtmant

of Psychiatry

New York Medical College
5 East 102m Street
New York, New York 10029

Attention:
Many
~

We

Miss K. Pelczynski
Room #2

.

Sincerely yours ,
Pink, {4.1).
Professor of Psyckﬁatry

Max

Mszp

-

�</text>
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                  <elementText elementTextId="103147">
                    <text>"“WVVVVZV'W’WW-nqv’p'u~w~VmV'l-ﬂmv&gt;:

hm"

-

.

mu

W‘mmwvmvwvn.vﬂ.qu-.‘wr‘r‘AI'v‘

.—

--.——

wr—

,, m—r—ww—_—..

_.w_rm...,.

.‘V»-...—,..r.,~.w W, .v—v. Au..."

v .m “raw

_

Fuww‘m

December 9, 1969
Dr. Arthur L. Peterson

Executive Medical Officer
Pennsylvania Hospital

111 N. Forty-Ninth Street
Philadelphia, Pennsylvania

19139

Dear Dr. Peterson:

Enclosed is a copy of our manual, which is sent with
our compliments.

If a supply is requested
be pleased to make these

for the use of residents, we
available, as long as the supply
lasts, at $2.50 each, or $2.25 for 10 or more copies. A check should
be made to the International Association for Psychiatric Research, Inc.
will
(or

IAPR,

Inc.).

Thank you for your

interest.
Sincerely yours,
Fink, ”.0.
Executive ﬂirector

Max

MF:kp

one,

7w.“

.,. w .,

.. .

.

"V

__,,

.-

�</text>
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                    <text>May

WW

Dmald

Petmm,

State Hospital

17, 1965

M. 1).

#1

Fulton, Missouri
DaarDon:

Mywwxymﬂxforymﬁmtfuhmsinmding
smisastmoolhctor?

mﬂammchillﬂmt-Daycm. deidymlcmtlntmy
Iwillincludemisinomoollectimmditwinbea

mindertmtmltmhasbemthesimofmofﬁwmm
world

mu

occasions in meant

history.

Sincerely yams,
ﬂax Fink.

M.

D.

Professor of Paydaiatry

Mfﬁcp

�</text>
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                    <text>D

ii

F
S

E

g

chember 14, 1966
Dr. F. R. Peterson

Bristol Laboratories
Syracuse,

New

York 13201

Dear Dr. Peterson:
There has been a great deal of work on the effects of psycho—
active drugs on the electroencephalogram, and this has included
studies of the antidepressants. EEG patterns differ for each
compound and for each class of compound. These observations,
especially those which have been done quantitatively, have been
useful in defining the clinical range and probable efficacy-9f
new compounds in psychopharmacclogy.
EEG

studies should be

.considered safe for

human

done in man as soon as the drug is
experimentation. If a compound in the

recommended dosage evokes no measurable

index for psychotropic drug efficacy

EEG

effects, the therapeutic

is probably very

low.

If

the EEG changes are still unmeasurable at maximum dosage ranges,
the compound will probably have little clinical merit. If a specific
pattern is evoked in electroencephalograms, the therapeutic index
can be defined with great accuracy.
Optimal methods vary. 'The techniques evolved during the
past decade started with visual descriptions, followed by analog
frequency analysis and analog amplitude analysis, and most
recently have been replaced by digital computer methods. The
present sophisticated techniques make possible accurate delineations
of the probable therapeutic range, if drug studies are dene accurately
and early.
.

While these observations have not yet been considered by the
present FDA as an essential part of a new drug application, the
reports have been of great interest and considerable support to
numerous pharnememﬁical clinical directors, especially those who
have had the opportunity to study quantitative data.

�Dr. Peterson

-2-

November 11;, 1966

A.laboratory for the quantitative evaluation of EEG criteria
being established at this Institution, following my experiences
as Director of the Missouri Institute of Psychiatry from 1962
to 1966.
It will be Operational in the late spring. Such quantitative EEG
evaluations can be undertaken in St. Louis by my associate,
Dr. Turan Itil, who now has the laboratory for clinical e1ectro~
encephalography at the Institute; and alSO by Dr. Carl PfeiffEr
and Dr. Arthur Sugeman at the New Jersey Nam-Psychiatric
Institute.

is

now

If additional data regarding these

interest, I

Street

would suggest you

(212 369—7900)

at

visit the

experiences would be of
at 5 East 102nd

College
your convenience.

_

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
mf:

kp

�</text>
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Jammy 'I.

1985

Peterson
Grass Instrument Canyons!
Mr. Robert A.

Quincy,

munchusam

Boar Mr. Patersm:
The

madam-in

'asiampﬁca.

the amplifier Guthrie

Wtable,

Wiﬁamgatdtoﬂnpaperwidﬁa.wehadmtﬂm
itwouldbelaasofapmblmifallmmmﬁmsuwdm"
pummbutporiupasimemia Mumtwillbeusodfwm
first year in a special project, 8" paper would be satisfwtozy.

Immmmdmﬂnmmmpapwguimmmpmdfor
than B", as indicated in your letter.

vim gnaw

Simmly yours,

m,
Meter

Max

2-1.1);

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                    <text>October 28, 1966
Mr. Robert A. Peterson

Instnnnent Sales

Grass Instrument Oouapany
Quincy, Massachusetts
Dear W. Peterson:
Your

letter of

October 22, makes

very
prior discussions with you and Mrs. Grass
the appmdmate delivery date was five months.I

my

me

sad indeed. In
was

told that

Afomalomderwas senton
20. Because of initial
conditional requirements intheDepartment, Icalled Mrs.
Grass

andtoldherthstthisomderwasfullysupportedbymepersonall.

AsItoldherinDenver,thsoonditionalnatheofthisorder
hasbeenremoved.

Afomalmtetothiseffeotisnwbeing

prooessedbytheOollege.
In moving from St. Louis to New York,
no equipment
withme. IanamimstogetthesepmjectsI brought
startedandhavem
other amplifiers to substitute. For this reason, delivery in
late March will mean that productive studies will have been

defmed formthanninsmonths. I canonlyrequest that
tothsextentthatyouoan,thatyov.1attempttoad1m~etothe

original time schedule. The Grass Instrument Company has
always had my understanding and this letter represents the
second time in our relationship that I have asked
yours.

‘

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

"‘ka

.

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                    <text>October 31, 1966

Peterson
Sales
Instrumnt
Grass Instrmnent Oanpany
Quincy, Massachusetts

Mr. Robert A.

.

Dear Mr. Peterson:

letter of October 22, makes me very sad indeed. In
with you and Mrs. Grass I was told that
discussions
my prior
the approximate delivery date was five mouths.
Your

.

formal order was sent on August 20. Because ‘of initial
conditional requirements in the Department, I called Mrs. Grass
and told her that this order was fully supported by me personally.
As I told her in Denver, the conditional nature of this order
has been removed. A formal note to this effect is now being
A

processed by the College.

In moving from St. Louis to New York, I brought no equipment
with me. I am anxious to get these projects started and have no
other amplifiers to substitute. For this reason, delivery in
late March will mean that productive studies will have been
deferred for more than nine months. I can only request that
to the extent that you can, that you attempt to adhere to the
The Grass Instrment Company has
always had my understanding and this letter represents the

original time schedule.
second

tine in our relationship that I have asked yours.
Sincerely yours ,

hex/rim,

M.D.

Professor of Psychiatry

“1ka

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                    <text>June 13. 1966

Mr. Hex Petechek

Argosy-Travel
140: Middle Neck Road

Great Neck,

New

York

Deer Has:
1 hope there will be e break in the reservation schedule so
you cen get ell of us on e direct flight to Tel Aviv. In
the meantime, would you please change my reservation no I
eon ecconpeny a friend who is returning on September 4, from
the 12:00 flight to the 10:45 flight, TWA 705. toutiet class,
London to New York.
Many

thanks.
Sincerely yours,
Fink,
Director

Mex

Mlljb

M. D.

�</text>
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                    <text>July 8,

1964

Mr. Max Petschek
Argoay Travel
lﬁOa Hiddlaneok Road
Great ﬂeck. New York

neat

Haas

I neglected to tell you that my friends lnslat that if I stay
in Istanbul, I moat be at the Hilton in a room overlooking
the Boophoruo. While I hate to be identified with the
American tourist who travels from Hilton to Sheraton to
Hilton. I would be foolish not to use the recommendations of
Dr.

Itll,

_It at

who haa

many

years.

all possible.

Hilton.

would you arrange
overlooking the Bonphotuo?

Please guarantee a
able!
My

lived there

full

moon ~

that our stay be at the

nothing else would be occept~

beat regards.
Sincerely yours.
Fink,
Director

Max

nor/1b

M.D.

�</text>
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                    <text>-

“a.“

Fm:

\“

lv'rlﬂ'v."

“WP-wk»

—.,-‘

w

rw

July 20,

196:;

1%. Max Petschek

Argosy Travel
lMOa Middle Neck Road
Great Mack, ﬂew York

DaarMax:

MM...

Please. send me tm statements for our account - one for
alone and a separate one for Martha and Jonaﬂxan.

In

my

account, include. the cost of

rm

air tmmpcr'tatim for

to Newcastla; also, please make a suitable amngmnt for us to get to Birmingham from 10mm on
Sunday, August 30 , for amival late in the afternoon or

Dr. Ulett and myself

early evening.

I will be in

New

York on July'BO, and

will

come

to see you.

Sincerely yours,
Max

Fink, Md).

Director

MF/jb

gum-um“...

.
Avg."

�</text>
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                    <text>March 12, 1965

Mr. 24a: Potaohok

Argosy Travol Servioa
140 a Middlooook Rood
Croat look. Long Ialand

Boar Hon:

Congratulottooa and our host wishos on your marriage. Wo all had
boon voodottns whothor you would find souobody hero or on your many
tripa. I on doltghtod that you found oouobody from‘VIonna. and North.
joins no in wishing you many happy yaarl togothor.

I as now planning my not: trip to Europa. Thorn
will bo an lotarnational wanting to Vlonna, and rathor than go through
formal ohannala to obtain a room. I would prefer ocoopcing your rocounoodatioo.
Spoaklog of Vionno,

3 to September
toquoot raoorvatlona for the period of September
would
no
1:11?
Turon
prefer
10 for uyaolt and also for my aaaooiaco. Dr.
olnglo tools with bath at your favorlco hotol.
Would you

Sincerely yours,

no: link.
“1:1:

M.D.

Profoaoor of Psychiatry

�</text>
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                    <text>April 9,

1955

Mr. Hm: Porsche):

have]. Service
my
1an Hiddlmck
Road

Great Neck. Long Island
Deer-Max:

Itilmdlwouldbepleeeedtoetayettmaotel
However, Hamid mferbeingfnc to eat with
mower delegates etthsommtim, ins-fumes Imeum
Dr.

Bristol.

thettheywillpmvidedimrmtinge.

Beaver, mldyoupleeee mfimﬁumexvnime met
I will minbtmee for whatever you have deposited.
'

Hazy

theme.
Sincerely yours,
Hm:

Fink,

H. D.

Professor of Psychiatry

Wzkp

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                    <text>July 12,

1965

Hr. Max Potschok
Argosy Tram]. Service
1an Hiddlaneck Road
Gmat Neck, long Islmd
Dear

Max:

Complications have arisen

in our

summer

plms in that

mdomtthinkthatmcmtakeourjointtxﬁptommo.
In
have

received another invitatim
part, this is became we
togotoGammyattMendofOotobarandm‘. Itilandl‘
would probably prefer this latter trip . We mot afford
both.

Themfm, would you please cancel the msewatims
thatyoutnvemdeformtoleaveinAugust. Withintl‘a
and: ten days I should lam mom about whether Dr. Itil
and I will he going in September or October and I will
write or call you at that rim.
Sincerely

yum ,

Fink, M.D.
Professor of Psychiatry

Max

HF:kp

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                    <text>July 13.

Mr. Max L. Petachck
Argosy Travel Servica,
140a Middle Hack Road
chat Rock. Raw York

1964

Inc.

Dear Max:
be
itincrary of July 8 scams satisfactory. and I wouldThe
make
would
arrangements.
the necessary
planned it you
only difficulty in the whole program appears to be the
flight to Tel Aviv,_and I know that yen are doing every~
thing possible about that.

The

Many

thanks.
Sincerely yours,
Ha: Fink, M.D.

Director

HF/jb

�</text>
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                    <text>June 26, 1986
Helen Pettinati, Ph.D.
Department of Research

Carrier Clinic

Belle Mead, New Jersey 08502
Dear Helen,

‘W’wt

‘WIV'VIWv-WJ1.W

.‘

m

"Vtml‘i'

Thank you for the copy of your letter to Mr. Chyung regarding an
assessment of the new Medcraft 8-25. 1 am delighted that you and your associates
will be undertaking such a review, and look forward to publishing it.
I have made good use of the MECTA/THYMATRON comparison, and it has
allowed me to answer questions about instrumentation by referral.

Would you consider a comparison with the ElCo'l' instrument, which Mr.
Schick states will be available ‘very shortly'?
My

best regards to you , Stephani and Ken.
Sincerely yours,
Max Fink, MD.

Editor

�</text>
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                    <text>J1me 1, 1985

m» Carl

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Nu Jamey Wyohiatxﬁn Institute
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effects, annually those drugs that affect bdnvior. As I have
Iamwriting
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Phi!

Fink,

H. D.

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my;
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                    <text>June 1. 1985

Dr. Carl

New

Pfeiffor

Jamey Nampawhiatrio Institute

Skillmn,
Dear

New

Jersey

m1:
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effects
study Which we recently completed on the methods
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10, 1%6

m. Carl Pfciffer

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New Jersey
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00.
17, 1%6

Dr. Carl C. Pfeiffer
ﬁned, Nameplmlogy
New

Jenny

Box 1000

Princeton.

Institute
WWW
Jersey
New

mead,
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in me Amaricm College of Clirdcal Musicology

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mldhnmpviata.
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Idamthmwkﬁdzlevelofmbamhip

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worship”
Sincerely yams,
Fink, 14.1).
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Max

mug)

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Dr. Carl Pfciffer
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the

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:13th
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Chemotherapy.

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Max

mac,

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Dr. Carl C.
new Jersey
Box 1000

Princeton,

Pfeiffer

Neuro~Psyehistric Institute
New

Jersey

Dear Carl,

-

EEG
You may recall our discussion of pyrovslerone
and
a
in Miami. 1 undertook the single dose~pilor study,
This
information.
for
enclosed
your
is
summary
preliminary

study followed our usual procedures, to define a minimsl
end/or EEG
effective drug dose which elicits behavioral
EEG
changes in the time period of our usual EEGstudies. The
profile study.
data is sufficient to allow s definitive
Copies of this summary have been sent to Turen Itil
end to Dr. Boyer of Nsrion storstories.
Trust you have had e healthy and relaxing summer.
My

best rugsrds.
Sincerely yours,
HI: Fink. MJ).
Professor of Psychiatry

ﬁrzkp
Cm.

�</text>
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                    <text>September 2, 1969
Dr. Carl C.

Pfeiffer

Jersey Neuro-Psychiatric Institute
Box 1000
Princeton, New Jersey
Dear Carl,
I regret there was an error on page four of
the pilot study report on 8/22/69. Please replace
page four with the one enclosed.
Sincerely yours,

New

Max

Fink, M.D.

Professor of Psychiatry

MF:kp

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                    <text>.v,...,.v-&lt;,.

..,.,,.

.

A

.

.W

.

W‘s-WH‘FHI'VL'.

September 17,

1981}

Wu

"rr'"

David N. Pfohl, MD.
Associate Medical Director
Biomedical Products Department

DuPont
Wilmington, Delaware 19898
Dear Dr. Pfohl,

i am in receipt of your letters of July 5 and August 14 regarding the
unusual experiences reported in patients receiving high doses of naltrexone. Please
be advised that I have not prescribed naltrexone for a number of years, and that I
have no supplies on hand. I do not recall any similar adverse experiences.
HTWWGMWWY'W'w-WW""

My regards.

Sincerely yours,
rm”,

2-,»

wam~

’(W'ﬂl‘bv'ml'Fﬁ

"

"'r'

as”:

w

Max Fink, MD.
Professor of Psychiatry

�</text>
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                    <text>5'me

February 4, 1969
Pharmaceutical Manufacturers Association
Foundation, Inc.
llSS Fifteenth,5t.. n.w.
Washington, 0.0. 20005
Gentlemen:
I would

like to apply

on behalf of Mr. Heywood Zeidman
stipend awarded by the PMA in the program of medical
student traineeships in clinical pharmacology.

for

a

Mr. Zeidman, a freshman medical
York Medical College, has become

student enrolled at
interested in a research
project involving narcotic antagonists. He will attempt to
develop a method of administration for naloxone and/or
cyclazocine to be released at a steady rate to provide extended
antagonism to heroin use.
New

This project will involve both laboratory and clinical
research with heroin dependent patients. He fill participate
in studies of antagonist administration, heroin challenges,
255, which are part of the treatment of heroan dependence.
He possesses a Master of Science degree in
pharmacology
and has completed many required medical school courses. He
is working with us virtually full time beginning immediatily
and ending in September 1969.

Thank you

for your cooperation.
Sincerely yours,
Fink, n.o.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>June 16, 1972

Exacuttvu Sacrutarial

International Symposium
Clinical Pharmacology

Pontiach

on

345

3-84 Eagensburg

West Germany 1
Guntlamen;

I obtain the noceanary rugistratiou information and
preliminary prograus for the moctings scheduled August 10«13. I
have submitted an abstract to Professor E. Garrett.
Hay

Thank you.

Sincerely yours,
Fink. ﬁ.ﬂ.
Professor of Psychiatry

Hex
MF:1g

�</text>
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                    <text>October 15, 1953
Mr. Sm

Philipa

Seimtiﬂc Data Systems
1M2 ﬁftwnﬁl Street

Santa Monica, Califomia
Dear

m. Philips:

At the and of 1962, this Institute reviewed various
system for on—lim digital analysis of EEG simian At that

m,mmupmymkindm1ghtoaendmminfomticm
I shouldbn mtoful

of models

910 and 920, and

formmt mt description
oquipmnt

anyoﬁurpmoont‘

mm
Ishmldalso

widehmybeappucabletowlinepmssim.

bephaaedifyouwwldarmngetoviaitwithmmyowmt
triptOSt. ms.
The

present system

(IBM 1710)

im
t
it.

review mud in the
of matter capacity,

event that you are able to supply aqui‘
like the opportmity to review
I

szd

Sincerely yours ,

_

Exam

N“ Pink.
Dimctor

M. D.

�</text>
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                    <text>.,.._....—11.,.‘

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,

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June l5, i970

Irv-""31-

"zrmw

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~

7......

Dr. Richard Philiipson
Hafionai lns+i+u+e of Menfal Health
5454 Wisconsin Avenue
Chevy Chase, Maryland 200l5
Dear Dr.

wmmoruVNow—n-

Phlllipson:

Both Dr. Al Freedman and

i

regreffed your prior commiffmenfs
on oplafe anfagonisfs.

that precluded your offending fhe meeting

have been encouraged by lhe lafes? ediforlai by Philip Abelson
in Science to summarize fhe proceedings and submi? These To his
Journal for publicafion. A copy is enclosed for your informafion.

We

“w

Perhaps

we may

meal soon

to review fhis dafa.
Sincerely yours,

rwmeW-m

1‘

Max

7..

Fink, M.D.

Professor of Psychlafry

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                    <text>ThSB—127SB
May

10, 197k

Burtcn J. Goldstein, M. D.
Dapartment of Psychiatry
School of medicine
P. 0. Box 875
Biscayne Annex

Miami,

Florida

33152

Dear Burt:

I was pleased to have an opportunity to chat with you in
thhington at the Anxiolytic meetings. I am taking the liberty of
enclosing a memorandum describing a fellowship which has Just been
established in this Department. You indicated that you had appli~
canta seeking Jobs.

criteria stated in this description,
grateful if you could bring them to my attention. I look
fbrward to visiting with you in Miami later this month.
I

Should any meet the

would be

Sincerely yours,

an: Fink,
MF:ed

Enclosure

"an:

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                    <text>W
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13, 1953

H. Pick-mt

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Dear Dr.

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                    <text>Am?!

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Dr. Betty H. Pickett

Wm

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Dr. Betty H. Pidcett

Executive Secretary
Career Program
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National Institute of Mental Health
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Pickett:

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med

on Mmday, Deoenber 16,

with Mr. Lewia Stuart: and Mr. mm
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of
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                    <text>November 16, 1963

Dr. Betty H. Pidcot‘t
Emm’civo Summary
Reseamh Career
Research Stunts 8 Fellowships

National

Institute of

andx

Manta]. Health

Department of Health, Education
8 Welfare

Natioml

Bark Building
Beﬂmsda lit , Maryland

Re:

NIHw-M—oRG/F

K6~PH~22.572

Dar Ir. Pidcott:

W

I look forward to your visit on Monday, December 16,
with Mr. Lewis Stuart and Mr. ﬂamld
I have
Hmke, officers of the Paydxiatrie Research Formulatim, to
to the Institute at 9209 mm. on their way '60 their of;1963.

m
ficea damtmn.

m

Dimmer af my Division of
m. George Ulctt,
Diseases, will be available all day. and we can an
range to met him at your discretion.
Manta}.

My ”swam will also bu available and the Imtitute
will be at your disposal. If you will let me'knm the
of

m
mm1.lshwldboploaadmpidcymwatassainﬁn
Simmly yams .
Executive Dimmer

�</text>
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                    <text>October 21, 1993
Captain Richard M. Pico, M.D. USAF MC
Wilford Hall Medical Center (AETC)
Wilford Hall USAF Medical Center
Lackland Air Force Base, TX 78236-5300
Dear Rich,
Thank you for your recent letter keeping me informed of your research.
The imaging work is interesting and you are to be congratulated on the drive. Such
imaging studies are becoming increasingly important in psychiatric research. I understand
that Dr. Edward Coffey has been invited to be a Visiting Professor at Wilford Hall. You
should discuss your proposals with him as he has done the most elegant MRI/ECT and
MRI/depression studies. His facility in Pittsburgh may interest you when you leave the air
Force.
there.

I do not plan to attend the Neuroscience meetings, so we cannot meet

I was in Austin last week, lecturing at St. David's Rehabilitation center. In
the face of the new Texas legislation forbidding ECT in anyone under the age of 16 [even
with parental and patient consent], there was a brouhaha at the sessions, with Scientology
pickets in front of the hospital and 3 disruptionists in the audience.

Good luck in your work.
Sincerely yours,

Max Fink, MD.
Professor of Psychiatry
and Neurology

�</text>
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                    <text>April 23, 1993

Captain Richard Pico, MC, USAF
Wilford Hall USAF Medical Center
Lackland Air Force Base, TX 78236-5300
Dear Rich,
Thank you for your very nice letter of April 5.
You should apply to NARSAD for a startup grant for your first-break

psychosis study. would be glad to support your application and provide the
needed letter as mentor/advisor. However, it would be better if your sponsor
were someone in San Antonio or at a neighboring city in Texas. The reviewers
are aware that distance is a deterrant to useful interaction. Ray Faber should be
supportive; if not, A. John Rush at Dallas is a good friend and would get the
two of you together if you are willing to get to Dallas. [If you have another
sponsor, will gladly write a supporting letter.]
I

I

I

am not sure what is best for your third year time, since do not recall
the constraints. The brain imaging laboratory at UT is at the forefront of a
national brain imaging database collection program, and am impressed that if
you came to master the techniques described at the ANA meeting, you would
be doing yourself an excellent service -- both for your science and for any
clinical future.
I

I

I

As for EEG, much good work has been done, but the neurologists
and electrophysiologists have a less sanguine image of EEG brain imaging than
do I. Newer methods, like MRI, PET, and SPECT are flashier. Newer methods
get more industrial and academic support [there is more money in MRI, CAT
than EEG]. Perhaps, the clinicians are correct, and we have reached the limit of
what can be learned in an individual case from scalp recording. do not believe
that we have reached the limit of EEG as a scientific brain imaging tool -- it is so
I

responsive to set and emotional change, so easily and safely recorded, so
easily quantified, and so much has already been done to relate EEG change to
behavior. can see no harm in getting to read EEG records by the usual page
turning methods; at the least, it will provide a source of income should you wish
to continue such work in practice.
I

Call me any late afternoon or evening at my home-office: 516 862
6651 and we can discuss this further.

Sincerely yours,

Max Fink, MD.
Professor of Psychiatry

and Neurology

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                    <text>/

STATE UNIVERSITY OF NEW YORK AT STONY BROOK

€-

Health Sciences Center - School of Medicine
'
De p :1 r‘ment
of Psychiatry
t
and
Behavioral Science

Mr. Gerald

Stony Brook, N. Y. 11794
Phone: 516-444-2413

February 6, 1975

\

Piel, Editor

Scientific American, Inc.
hlS Madison Avenue
New

York, New York

Dear Mr.

U

I

’lfz/I’,,..———e'v“

w

10017

Piel,

two topics for your consideration
-—
American
the effects of seizures (con—
for reports in Scientific
vulsive therapy) on mood and behavior in man, and developments of

I should like to suggest

quantitative electroencephalography in the study of psychoactive drugs.
These topics are quite singular but there are peripheral relationships'
educa—

which makes their review complementary.
tional and social reasons.

Both are timely for

is based on the observa—
tion that repeated seizures at daily intervals elicits long—term’effects
on mood, thought processess and affects in man. It is effective in
as a treat—
allevi ting severe depression and mania, and was developedcoma
(insulin
Convulsive therapy:

This treatment

de in the 1930's, concurrent with studies of daily
coma) and leucotomy (psychosurgery). Their concurrent development has
led to some confusion that these treatments are equivalent, and the
View
same name, "shock therapy" is erroneously applied to all. Many
few
decades,
their mechanisms of action as the same. During the past and leucotomy
however, insulin coma has been replaced by drug therapy,
(psychosurgery) has found a limited niche in the treatment of a small,

ment

m

well defined group of mentally ill. Repeated seizures, in contrast,
are used more widely, and in comparison with other therapies for de-

pression, exhibit better therapeutic results.
While it is customary to say that we know little of the
.
mode of action of these therapies, the opposite is true. The neuro—
seizures
physiology of the seizure and cerebral sequellae of repeated the
induction,
seizure
the
of
The
parameters
have been defined.
on perform—
effects of different electrode placements, and the effects
known
of the
While
is
less
studied.
been
have
and
memory
ance tests
modern
the
to
much
relevant
is
that
biochemical effects, there is
‘

I

�-2biogenic amine hypotheses, and some unique studies of cholinergic
mechanisms are particularly contributory to our understanding of the
role of neurohumors in brain function. Indeed, it is fair to say that
we know as much about the biochemical aspects of seizures as we do
about antidepressants and sedatives.

basic science point of view, the ECT process contributes
to our understanding of seizures (epilepsy), the role of cerebral hemis—
pheres in behavior and particularly, memory; and such psychologic mechan—
isms as the role of personality in depression and changes in task
performance with changes in brain function.
From a

educational point of view, a presentation of the ECT
data may alleviate misconceptions about 'shock therapy' and provide
independent information to allow the reconsideration of laws restricting
seizure therapies now in force in California and under consideration
elsewhere.
From an

Some of the recent physiologic, biochemical, and psychologic
data were brought together by the NIMH in a conference, published
in mid—1971; entitled, "Psychobiology of Convulsive Therapy", edited by
myself, Seymour Kety, James McGaugh and Thomas Williams (V. H. Winston,

(memory)

Washington, 197h).

‘

z

Quantitative ElectroencephalOgraphy: The measurement
of the electrical activity of the brain has been a subject of interest for
more than four decades. During the past 15 years, the development of
2.

-

sophisticated quantification methods based on digital computer programs
and an understanding of the requirements for contrdued experimentation
has defined applications in psychopharmacology which are of general
academic interest. Psychoactive drugs, hallucinogens, and drugs of
abuse have defined effects on brain function in the alert subject. These
effects are drug specific, that is, each compound has a defined signature
which is used to classify the compound. When new compounds are assayed,
EEG classification provides a prediction of their clinical application
before

human

trials
The

are undertaken.

techniques are sufficently well developed to assess

dose response curves and to measure bioavailability and neurophysiologic
equivalence of compounds. Lately, the EEG methods have been compared

with blood level measurements to study the pharmacokinetics of drugs

affecting the brain.

Quantitative EEG has been used to develop automatic sleep
classification scoring systems. Parallel with these systems, is the de—
velopment of automatic drug classification systems.

�applied to problems outside psychoIn
pharmacology.
our understanding of the ECT process, the methods have
shown that electrode placement and hemispheric localization are contributory
to clinical effects. The methods have been used in studies of drugs of
abuse, particularly in the role of THC-delta-Q in cannabis, and in
examining the realtions between heroin and methadone and their interactions
The methods have been

with narcotic antagonists. Some students have assessed the effects of
hyponsis, zen, and transcendental meditation using these methods with
some success.
.

From an educational point of view, a discussion of quantitative
analysis would be of interest to psychopharmacologists, neurophysio—
logists, psychologists, and drug abuse specialists.
EEG

I commend both topics to your consideration. In part, this
occasioned by discussions with Dr. Alfred M. Freedman of the
New York Medical College, who has been a firm supporter of these programs
for many years. Should it be useful, I can supply the usual literature

letter is

and suggest the names of
Thank you

scientists

who

are active in both research areas.

for your consideration.
Sincerely yours,
Fink, M. D.
Professor of Psychiatry

Max
-

Merd

�</text>
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                    <text>"-

-w

an»

w-.r&lt;y—,—.»n

unnrmmw

September 14, 1971
Mr.

Pierce

Immigration Service
20 West Broadway

New

York City

Dear Mr.

Pierce,

Following our distussion, I am filing the enclosed
B-l petition on behalf of Alexander Maurice DON of Johannesburg,
South Africa. Dr. Don, who received training in psychiatry
with me in St. Louis in 1964-65, has been invited by this
Department to join our faculty. His experience in psychopharmacology
equips him to develop a special program in the treatment of
opiate dependent veterans who are now being admitted to the

facility at Montrose,

York. Through our Dean's Committee
we have been asked to
establish the treatment program on a ’crash' basis, recognizing
the emergency nature of the problem as outlined by the

V.A.

New

affiliation with that treatment center,

President in June.

Dr. Don Besires to emigrate to the 6.5. The consul in
Johannesburg has indicated to him that no visa can, in due
course, be issued prio to December of this year.

It is our belief that his early arrival will permit us
to establish the treatment programs when they are urgently
requested. We do not have the personnel to establish this
unit, and have invited Dr. Don to do so.
We

would be

grateful for your assistance in bringing

this scientist to the United States.

will reimburse your office for the cost of cables
to Johannesburg pursuant to the authorization under this application.
we

Sincerely yours,
Fink, M.D.
Professor of psyciatry

Max

�</text>
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                    <text>Docenbcr 3, 1971

A. Grace

Picrcc,

H.D.

Associate Director of

Clinical Rasearch
Ortho Rnsoctch Foundation
Raritan,

New

Dear Dr.

Pierce:

Jersey

08869

1 look forward to seeing you on Wednesday morning at
I have received the description of ORF 8063 and look
forward to discussing this with you.

11 a.m.

Much of our work is focused on a dcscription of the
chanson induced by psychoactive drugs. In anticipation of
our discussion, I an mending you'two recent summaries of our
work.
EEG

Sinccrtly yours,
Fink, H.D.
Profcocor of Psychiatry

Max

31:13
lhc.

,

�</text>
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                    <text>73SBw6h983

April 27. 1973

m:

”Orton 9.

F203:

Max

SUBJECT:

Psychopharmacology

Fink,

Mill”.

Md).

M.D.

Fbllowing your request of April 18th. I upoko
with Dr.
dar Klaat, and VII untoninhad to find
thsk while the studnutn have had introductory pharmacology
(15 lectures), they have had limited exparience vith
drugs affecting the autaaamic nervous syntem. but g3.

th

exposure to ysychopharmacology. Should it be the policy
of the department to provide a background in basic
psychopharmncology? This is a very larga subject,
encompassing, at a minimum, the following topics:
1. Mbdo of action of OHS drugs;
2. Blood#bra1n

barrier

and

its effects;

3. Cerdbrnl neurohmuara. theories of mode

of uction;

h. Neuraphyulologicnl hypotheses, drug

effects;

5. sedatives und hyyuotien;
6. Analgesics, narcotics and
T. Psychotrbp1cu

anxiolytics;

their untagonlats;

(antlplyehntic drugs) and

8. atiuuluntn, nuttdaprenlgnts and thyaolupeiau;
9. Hallueinoganu and dolirisntn;
10. Alcohol, catttino, thaobroulnc.

ctc.;

�\/
Mbrton G.

Miller,

K.D.

~2~

April 27. 1973

11. saisureuproduaing ngentu and antinupileptic

drugs;

12. Ant1~Purk1naon agents;
13. All the can: an missud.
This could be argumiseﬁ by Harlin, Wbrtia. Klein, and
myself, requiring 9~12 hours if done wall» 3-6 hours

with

MF/iJ

same

difficulty.

�</text>
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                  <elementText elementTextId="106767">
                    <text>My 16.
Janna
VA

Klett,

1973

Ph.D.

Eerry Point, Maryland
Dan: Jun,

It

van a pleasure to vnwk with you and Sun in Dcnvnr.
study sauna well~1n~hand. and the investlgntorl lean enthusiastin and cooperative.
The

is a reprint of the study of laboratnry tests
associates and I carried out in Missouri as part Of tho
ECDEU program. It suggests that concurrent inborntory
tests in
taxable controls provide the prlncipnl comparison for evaluating
whcthnr a new drug alters laboratory tests: the rcnaons include
variations in laboratory standards, tnahnicinns, tin: of ynur
Encleaed

which my

Ima

season, etc.

Holden went on to dcacrfbe significant changtl in
tutti. when comptrod to concurrnnt controls. with
receiving thioridnsinn and/or chlordianapoxido (Chadd. Pbyoh.

lnbarumory

pittants
J. 14:299~301. 1959); and in unothor study. in patient:
rnceiving hulapnridol (Biol. Pnyeh.3: 173~182). (I helluva there
.3 also a more rocont rcport. bun I do not has.
it in.uy lib.)
I would luggnst, thnrctorc. that tbs boat control will
be concurrenﬁ Iluplal in thn patient: ronclving mathndonn, ﬁnd nhnt
Anson.

~nll canpnrisonn be botvuon the sroupn, rcthdr than nautnnt taxﬁbook
or proncntdblinhod lnborntory standards.
One

indiaatod than

other point: the printout of the urinounnnlynctn. nrino. If the tent

no subject hnd conning in
was not coup. in would b. butter to mark

rnnhcr than

this :- "E.D." or ”—-".

0.0-- rooqrvina thls notation for
I look fnrvnrd to grouting

n ronl 'nngntivu’.

you ’nmunsat'

in August.

Sinoarnly yours.
Fink. M.n.
Professor at Paynhintry

Mix

�</text>
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                    <text>January 31, 197‘
Costa. Stafania. M.D.
Univaraity of Athana School of Mbdicina
Athana. Graaca
Boar Coataa,

Enéloaad are topics of the two summaries which wt
submitted to NIDA yaatarday. In addition, VI aunt 16 voluuaa
of tha data output: (the material that
brought last spring and
tho output: of tha work dent by Aria this auanar) as v.11 as
copiaa of the raporta which ﬁt made in 1971 and 1972. I
boliava that the reports warn wall aactptcd. although Rhaa
told ma of many quastiona that wara rained.

it

I have aakad hat to list the quastiona and as soon as
I have then , I will aand than on to you. If tho NIDA
allow: an axtanaion, wt may be abla to Intuit a daftnittva

roport. hopafully written together. which may answer
chair qua-tiona as wall as our own.
Plaaaa «stand

Athana.

my

hast wiahaa to out

many

some

frianda

of

1n

Sincerely yours,

Max

Fink,

M.D.

Protester of Psychiatry

mf/ca

�</text>
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              <elementText elementTextId="58813">
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                  <elementText elementTextId="103746">
                    <text>a~mm&gt;‘-5.

..

.

.. “my...

.HV—pw‘

‘7:

n/‘v‘

-

..

.v‘.

.-.,.,;

....

.

1.

raven-u

—-y.~nw."(‘~

April 27. 1973
Dr. Gra¢o Pierce,
Orthe Research Foundation,
Route 202,

Barihan, R.J. 08869.
Dear Grace.

Enclosed is a signed FDA 1572 fbr the OR? 8063
Itudy in Ankara; and the anrricula vitae of Dr. Itil

anﬂ munelf.

'

For shipmsnt of supplies. and far record purposes.
the aﬂdrens of the project officer in Ankara is:
Albuy Dr. Sevket Akpinnr,

Celikkala sokak,

3/10 X13113: ~ Ankura.

Mk3?»
A",

v
:r.

my

A

v
w

best resurdn.

'?r'.-Wnrw

Binneroly yours.

r
:z-x-rs-vu

uh: rink.

M.D.

Prorontqr of Puyuhiatry

ur/id
aunt.

�</text>
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                    <text>7385-65}:
Ami}. 30, 197 3
".x“

-

V,

.

‘:
_,

Dr. Ward

Rev York

vumu.

Pim.

Meal
Her!

College.

10595.

,—..

Re:
:v'mmmumwgrweve.“ourr.,v;4..u«

Deer Doctor

I

Volevke,

3g

ﬂaw.

M,

.

Pim,

pleased to reconend the mutation of Jen
, when: I have known for more than five

am

1-1.1).

yearn.

In 1967 I visited Prague and became acquainted
work and that of his Chief, Jiri Boubicek.
A1 Freedman end I invited both or them to Join our
Department end in 1969 they both cm to work.

V1151:

his

During the“ were Dr. Velevhe has made
eignifieent contributiane to our study 121-0ng in the
effects of psychoactive drug: an brain function,
Mleuerly in our studies of ambit, heroin. and

”ﬁnk“.
He

worker.

in

I

e.

am

reeponnible meetigetor, and a diligent
pleased to recmend him for promotion.
Sincerely yours .

ﬂex Fink, MD.

Mfeemr of Psychietry
WI 13

�</text>
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                    <text>751-0381
24

January 1974

Br. Staphan Saara
Rational Inatitota on Drug Ahuao
Rational Inatituta of Mantal Baalth
5600 Fiahar’a Lana

Rotkvillo,

Maryland 20852

Ra:

Daar Dr. Saara:

33H 42~70-98

I an plaaaad to tranaait tha auunary reports of tho study,
ggrogic gaghiag Uaarg in Greaoa (HEM 42—70-98). Na have aut—
aaritad all tha obaarvatioaa of tha thraa yaara of this affort
and submit thaaa as wall as oopiaa of tho data upon which the
summary is baaad. The 1d volunaa of tha appoadioaa inoluda:

distribution;
(2) control population distribution;
(1) population

(3) summary of acuto aduioiatratiOn Tﬂc,

hashiah, and marijuana

statistical analyaoa.

(6)

Tho auunary and

Haw

York and

trials;

tha data voluaaa rapraaant both work dona in

in Athana.

In tha aunuar of 1973 wa undartook tho withdrawal studios.
Sixtaan aubjacta want through the prooaduraa and tho data are
now in avaluation-tha EEG tapaa are in analyaia in How York,
tho bahavioral and psychological data in Athaaa.
Tha aobuiaaion of thaaa

raporta couplataa the

work under

h2-70~98, aa raqoaatad up to Jana, 1973, arcapting
Contract
tha withdrawal data. It was humanly impoaaibla to complete the
data oollactioa of a withdrawal study, aa wall aa tho analyais
of thin complex aatarial, to aunaariaa tha findinsa as wall as
complatins tho raporta of tho othar parts of tha study program
prior to the propoaad taraination data of Datambar 31, 1973.
In aubmittins the material today, wa boliava ua hava complied
with tho contract to the boat of our afforta.
HEM

Excopt

Copanhagan in
praaantation or publication of tha data

for a nathodological praaantation in

1972. an hava withheld

of thia study.

In diacuaaiona with Professor Stefania in October.
would ba 'taaantad and publiahad

to agraad that three raporta
during 1974:

�Dr. Stephen Sgsrs

~2*

24

January 1974

(l) Psychological Effects of Chronic

Beshish Use-Anoricen Psychiatric

Association,
(2)

Effects of Cannabis
Preparations in Chronic Esshish UsersJournal of the American Medical AssoEEG

and Heart Rots

ciation;

(3)

May, 1974;

EEG
EEG

and

Effects of Chronic Hoshish UsenJournal.

Because the materiel is extensive end findings on clesr,
they warrant extensive explication with supporting evidence.
Professors Stefanie, Freedman, end I hove agreed to formulate
this in e volume which we believe can be prepared by nidosunnor

end published

I had

in

1975.

that either Professor Stefanie or one of his
join us in the analytical phases in December end
Jennery, but this hes been impossible because of their teething

staff

would

hoped

loads. The reports have been completed using mail service.
After the encumbrances of funds ere cleared on Jennery 31,
there will remain an unexpended amount of approximately $4,000.
Professor Freedman, as President of the Amoricsn Psychiatric
Association, was able to arrange for the presentation of the
psychiatric date at that meeting in Hey. We would like to invite Professor Stefanie to do so.

request on extension without additional funding to May 31,
1974. to complete the data analyses of the withdrawal study, to
we

allow Professor Stefania to present some findings at the
and to work with us in the formulation of s volume.

APA.

letter is an offer by the contractor to extend the
contract without additional funds, for these purposes.
This

On

behalf of the International Associstion for Psychiatric

Research, Inc., Professor Freedman and his coworkers at the New
York medical College, and Professor Stefanie and his coworkers
at the University of Athens. I wish to express our gratitude for

�Dr. Staphan

Star;

26

~2~

January 1974

the faith and support which you and your asaociatou have had
its inception in Juno, 1970. The data
of this program have boon moot intctasting and in believo will
make an important contribution to tho complex litaraturo of can~
nabis nan. But abate the facts, no believe w. have demonstrated
that ctoos~cultura1 roaoaroh is foasiblc and doopitc physical
distances, cultural difforancea, and longuago barriors, acionr
tints of good faith can accomplish conplcx missions. Hi trust
that your flith in this program is rewarded by the data horoby

in this ptogram since

831381€9.06 0

Sinceroly yours,
Max

MF/cio

Encl.

Fink,

M.D.

�</text>
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                    <text>21 March 1974

Gerald L. Klerman, M.D.
Erich Lindemann Mental Health Center
Government Center
Boston, Massachusetts 02114
Dear Gerry:
Thank you for your kind comments regarding the APPA. I
think that the Association should consider the suggestion of

developing

its

own

journal.

I have taken your suggestion of a review of the ECT literature to heart. I had completed a review of the proceedings
of the conference on ECT and will now add to it a specific re—
ECT

clinical results.

view of the

Thank you for your suggestion.

In talking to you about yOur relationship to the FDA, I
because, as I mentioned my letters
to Gardner and Scoville regarding the use of ele—trographic
measures for bioevailability, you seemed never to have heard
of this question. In checking my files, I find that my letter
to Gardner of July 16, 1973, and my letter to Scoville of December 20, 1973, have not been answered. My files indicate that
I sent a copy of both to you on December 20. Perhaps one of
the actions of your committee might be to provide closure to
suggestions such as this, for at least it will mean that some
consideration has been given, even if rejected.
was momentarily embarrassed

Again,

my

thanks for your comments.

My

best regards,

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

MF/cis

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                    <text>20 March 1974

Robert DuPont, M.D.

Dirootor
SADDAP

and HIDA

726 Jackson

Placo, u.w.

washington, D.C. 20500
Dear Dr. DuPont:

days ago, I received an inquiry from Jon Volavko, H.D.,
hood of tho nourOphyoiolosy division of the Department of Paychiatry, Now York Medical College, regarding ohargos for pro~
cousin; of EEG data. He indicated that he had proposed to SAODAP
that his laboratory process rocordo in tho SADDAP Collaborativo
Hothodone-Lovomothodyl Study. As a juutifiootioo for his budgetary
request, be indicated that using our facilities Would cont $100/hour
for machine time for processing.
Two

I um'writing to indioato that thin to a gross error. This
laboratory was established by tho ﬁattonal Instituto of Mbntal
Health. and no have prooooood data of intorost to that Institute
as wall as to NIDA at oithor no direct cost; or, where funds were
available, at rates from Sllrocord to $5.50/hour. HSMThe latter
é2~70—98,
chargo in tho one that has been used in Contront
and is well bolow the ontinato approvod by the contracting of~
ﬂies: in 1970.

In July, 1973, following mootingo of tho V.A. Study Group
and Morhodono, I submitted a letter, dated July 27. 1973,
to Dr. Sam Kain indicating tho costs which I projectod would be
incurred in oollocting and procoaoing tho V.A. lovomothadylvmotha~
done data. A copy of my budgor of that dato is attached. You
will note that the principal coat in equipping the laboratories
for proper recording. Hora, too. on indicatod that our cost was
$5.50/oooh1no hour, but booauoo of the proposed duration of
rooordinso and tho mothod of collection. we oorioatod a cost of
$1,000-1.200 for 90 Iubjocto rooordod at 4 separate occasions,
ouch occasion of 30 minutoo' duration.

for

LAAM

~1-

�" --- yr

"V" n-

pr-w"an n:

:m‘w’v-HI- vk-‘v‘r'v-

quuat-‘wwr-K

1w. mu...“

. .

,. ”Fm.

7’

.«ﬁ...~....w,....(_m',_....,,d_w..

WA.

.31....

W

‘-.,

”M. Mr r.rr.w--.‘~,

.,._.

,vn “my",

21.... be advised that this not: is vrtttan not as an offer
:9 pgrtieipace in your study program, but to elnrtfy a groan dis—
tortion in quatacion 3560 by my format unionists. I would be
{ztnt;fu1 1! yam vauld dirncc this information to tha appropriate
offiuor in your organisatiun so thgt tha records can be enrrecccd.
Sinccraly yourt,
Hm:

rink.

H.D.

Protannor of Psychiatry

HI/ais
Baal.

�</text>
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                    <text>was“?

June
m_m_.___mw“hwy--.WWW“__,

mmmwm

my

man

Re : Mii 08597-03.

ﬁends J. Pilgrim,

{Stunts

Ph. D.

Prom Specialist

Research Parents Branch

National Institute of Mental Health
National Bank Building
Bethesda, Miami 2001*»
Dear Dr. Pilgrim:

'

Wingﬂnpastmhalfyear.w.eersimhssbsen

actively involved in confirming in their patienm the blocking
the ditmn indmd mameffects of veriom 6:
mimt
monitori
ale
been
seesims
have
in the ass labore—
these
sis.
of
with
In
v
a
(ailerprmzine,
tmy.
ety

2-

Weenies
mm
mneemedaboutmedesemﬁm
gammawembem
relationships. Dr. Gershon and I am madam ts be hale to
adainistermmmmsatasetmteandfwmsmsm
would like to
a cmtimms slow inﬂector. The least

We
at a cost at

emiveandbestmieleehave
frat

[imam

fame

isﬁwCPalnerFlSS

approximately $300.00.

I am not sure whetmr it is
obtain
special pemissicn fen sud: a;
necessary for m to
when
than $500.08. In any me. my
is
sun
less
the
purdme
2 have your approval to tramfer the sun of $300. 00 free
from the regulations.

Personnel (avaiMle became of delayed mendting) to

Equipment,

for the

We of this immanent?

Sincerely yours,

‘

D.
Fink,
m
Executive Dimtor
M.

shew»:

�</text>
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                    <text>State University of New York at Stony Brook
School of Medicine ~— Department of Psychiatry
Max Fink, M.D.
Professor of Psychiatry
PO. Box 457
St. James, New York 1780

Phone: 516 444-2929
516 862—6651

Fax: 516 862-8604

1

July 8, 1994
TO:

FAX
FROM
FAX

Dr. Sweeney Pillay

617 855-3754

Max Fink, MD.
516 444-7534

7

The citations you requested are:
Fink, M. :EEG and behavior: Association or dissociation in man? Integrative Psychiatry [in
press, 1994]
Fink, M., Irwin P., Weinhold P.: EEG proﬁle studies of clozapine in volunteers and psychiatric
patients. Neuro-Psychopharmakologie1979; 12: 184-90.

My best regards to Jonathan.

�</text>
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                    <text>Dummy 3, 1964

Dr. V. S.

Pillutla

Senior Registrar Psychiatry
IMMUNE, Hospital
Bridgmd. 61.3mm

England

Dear rm.

Pillutla:

for your imuiry. The Pﬁssmri Institute
of Psychiatry is the research and training center of the Divisim of
Mental Diseases of Missowi. It was establiskmd in Catwar. 1962, with
labomtozy am clinical facilities for museum. At thc pment time.
of 150 beds, we am utilizing 70 for research purposes. Womtwies
are established in macaw, psydxolom , and clectxmncapmmgmpny.
Thank you very much

as well as a computer center

fw both statistical and PEG malyscs.

Thane is a specialized psychiatric march library as; a
of the Institute. Animal facilities am now being built.

want part

In additicm, them is a fully qualified three-year mychiau-ic
residency training pmgmm at the Institute, and a special Wing pro—
gram in clinical psychology is being established. Both in the research
the Institute is affiliated with
and in the training
the Department of Psychiatry of Washingtm miwmity School of mdicine.

prom,

prom

Atﬁnpzmenttim,ﬂmreamanunberofmmmhpmmin
of
the

use
progress. These include Lithiumas a thcrapy for maﬁa;
Yohinbim m a pmcipitant of mxiety and the development of anti—anxiety agents; mlation of EEG patterns and organic factors in the
treatment of therapy resistant payohccics; computer analysis of the
elccu'oancephalcw; the effects cf dmg withdmnal an behaviw in the
of paychatics by
and the
mktiomhip
duonically
therapy.

ill;

mtmnt

me

�Dr. V. S.

Jamary 3,

Pillutla
196*;

Page Two

Aoowmdations am availablo for rental or for solo within
ten minutes of the Institute. It is om:- oustm to provide ten-pox»
my aooowmodatiom at the institution for soiontists appointed fm
overseas.

Appointments are undo

.

&lt;

7...!

&lt;

,yw.,,ww.—w-v._~.1v

perianoe with a

at salary levels

WWW with ex-

salary being $12 ,000.00 per mum. In
addition to research experience , satisfactory mistrial of the DPM
is weighed heavily in the oatomdnatim of salary. Satisfactory oomwith oither a temporary or permnt
plotion of the ECIMG
oertifioam is pmroquisita to appointmnt.
I am enclosing a 1962 doaoziption of the Institute. If this
opportunity intomsts you, I would appreciate a copy of your curt-ioulum vita listing ammlogioally your oduoatimal and professional
experience. In additim, a small photograph and the name of at
least two mfomes to ohm we may write would be amt helpful.
minimum

omen

Sinoemly yours ,
Max

Fink.

Director

Mleg

fine. 1

M. D.

�</text>
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                    <text>January 29,

V. S.

Pillatla.

1960,

M.B.B.S.

Senior Eagistmr Psychiatry
Pbrgamwg Hespital
Bridgand. Morgan
England
Dear Dr. 9111mm
We

have

mvimd your mdanﬁals

and firm! them most

satia-

factozy for participation in the program of this Imam. imam.
the suacaasful canplcﬁm of the E.C.F.M.G. emmtim in a mam-y
prerequisite to an appointnant. I how of no legal way of
that emdmtim
ing the regulation and will momma: you to
of
Upen
that
notificatim
receipt
satisfactorily.
mdxmnt has
mum,lwillbaplsaaadtopmentymmmniammvitamdmden~
rials to the Director of the mvision for his midamtim for appointmt at that time.
Good luck in your

ml“:m

mum.

smartly yours,
Max

Fink.

Director

fomlg

Mo Dc

amt-

�</text>
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                    <text>April 21, 1971
Dr. Neiton

Pilpcl

Department of Pharmacy
Chelsea College of Science

London, England
Dear Dr.

Pilpel:

I have read with interest your report, “Tablets are not
8 issue of new scientist.
Your focus on
drug formulation as an essential part of clinical pharmacology
has been brought home to us in one of our recent problems.

pills" in the April
Since 1955,

we

have been

interested in developing

a

narcotic

antagonist for the treat-ant of opiate dependence, and while
excellent agents are available, their duration of action is too
short for clinical practicality. We believe that a formulation
which may be effective for weeks, or even months, would be most

useful.

enclosing a copy of a report of work in progress. If
if other concerns in Britain may be able to
contribute to the study of this problem I would be pleased to
discuss it further.

I

am

your laboratory, or
Thank you

for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

HFtkt
one o

�</text>
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                    <text>r,

,

muwm~

January 25, 1983
Dr. Roger Pinder

Scientific Development Group

Organon
Oss, Holland
Dear Roger,

I have made reservations to arrive at Schiphol at 1550 on Tuesday
afternoon, February 22 on KLM 2%, after a 1445 departure from Frankfurt; and
also for the KLM 6‘53 flight to New York, departing Schiphol at 1700 on Wednesday
afternoon. (I can extend the latter for the next day, if that is useful for us.)
I would be grateful if you would arrange for a car and driver at Schiphol,
and for a hotel in 055 for Tuesday evening. 1 will leave the programme up to you.

Thank you for the recommendation regarding the mianserin meetings in
am scheduled to give a paper at the Society of Biological Psychiatry
sessions in New York on April 29 - May 1. l have asked the Program Committee
chairman to schedule the lecture during the latter two days, if possible.

Ireland.

I

My

best regards.
Sincerely yours,
Max Fink, MD.

Professor of Psychiatry

�</text>
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