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                    <text>June 11, 197h
/

“K5,"!

{oven Simeon,

M.

D.

Missouri Institute of Psychiatry
shoe Arsenal Street
St. Louis, Missouri 63139
Dear

vaon:

At the ECDEU meetings. you delivered the EEG data cards
and a protocol for the Mellaril Dexedrine, placebo study in dis~

turbed children; with a request that we suggest additional analyses.
To get a better idea as to what has been done, you recommended I
discuss the data with Dr. Hugue.

I did so today. and was told he has completed t~tcst ,
discriminant function, regression, stepwise regression; and d
analyses. He does not have a copy of the report, but recalls
being able to discriminate drug effects. He also recalls corelational analyses using behavioral variable with the EEG.
Before recommending e data analysis, it would be useful
to hone the reports of the previous analyses,tor a sfmple replica- It
tion of analyses would serve little useful purpose. If you lack
the reports, perhaps Turen has copies in his files; or, even they may
still be at MIP.

I will hold further processing until I hear
My

from you.

best regards.
Sincerely yours,
Fink, M. D.
Professor of Psychiatry

Mex

Merd

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                    <text>March 25, 1983
David Behar, MD.

V.A. Medical Center

University 6: Woodland Avenues
Philadelphia, Pa. l9l04
Dear Dr. Behar,
As a start on your questions of 3/21/83, you may search the APA Task
Force Report #14 (1978) or my book (Convulsive Therapy: Theory and Practice,
Raven Press, N.Y., 1979). Both present the incidence of mortality in ECT. It is very
low, and as a consequence, it is very difficult to define 'risk factors'.

For morbidity, the question must be refined, since there are many
consequences of the ECT process, from hematoma at the injection site or postseizure excitement to complaints of amnesia. Again, the two books will help you
refine your question.
know of no studies of ECT in right (? _v_§ left) cerebral lesions since EC!”
is not ordinarily used in individuals with brain lesions. There is an extensive
I

literature of the safety and efficacy of ECT among diabetics, patients with thyroid

dysfunction, and hypertensives; and some case reports of patients successfully
treated in the absence of adrenals, with Cushing's syndrome, 939. Again, some
focus can be gleaned from these two volumes. For more recent material, you may
wish to write to Dr. Arthur Gabriel at the Mount Sinai Hospital in New York City.
He is an electrotherapist with an extensive experience with medically ill patients.
Sincerely yours,

Max Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>"navﬁmizm‘m

«—

_x

n

r-n
V

m“.

.,_.,w—u—r—u'm
w—m warn.

.

vw.

V

‘

mun

.

,
raw“

u.,-

[rs-raw

nr-"~',—-'rVr

.. v ”duh".-

..

v

v. .m.

*‘ “UV—r-

-~-

ww—r

v

m

.— m-I

--

an."

. q

.»

U'JW

‘nrqwc..._~

December 16, 1971

Arthur J. neikman,
15 Muir Avenue

M.D.

Mill Valley, Calif.
Dear Dr. Deikman,

with some
on Bimodal Consciousness
because you focussed on EEG evidence for

I read your report

interest, particularly

the concepts. The references to the EEG patterns associated
with the two modes of consciousness were illuminating. When the LSD
phenomenon was discussed, however, the EEG data was presented
ambiguously. The EEG effects during the EEG state are well defined,
an
exhibiting a shift of the mean frequency to a higher frequency,
of
(periods
with
seconds
'drop-outs'
increase in the number of
and delta activity.
flattening of EEG activity), and a decrease in thetamode
would be in
action
the
would
that
expect
Using your model, one
mode.
of
the
receptive
force, but the description is that
some of

is the state of delirium. In this
patterns are those of increased fast
state, the characteristic and
theta activity, and a decreased
frequencies, increased delta
The
subject is active, restless, and
responsivity to eye Opening.
outwardly, in the action mode; but the mental state is so severely
dissociated that it would be best to identify the state with the
Another problem for me,
EEG

receptive

mode. I think.

Finally, you will be interested in the recent data presented
by Itil and Ulett on the problem of EEG changes in hypnosis, and the
ingestion
reports of the EEG changes with acute cannabis inhalation and
and
decreases
which show increases in the alpha percent time,anplitudes,
in fast frequency.
Perhaps, in a later presentation, these data
integrated into the concept.

may

be

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

P.S.

My

best to

Dave Metcalf when

next you write.

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                    <text>February 15, 1966

Hr. Nathan

Balm

Data. Coordination

Chas. Pfizar and

amtm,
13w

Conn.

my, Inc.

06330

Mr. Belchem

mm,
Wammmlwin
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assist
prom.
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of

101:

#332647”;

was

received.

us in our waning study

$1110.me yours.
ﬂux Pink.

was:

co: m.

MAD.

Professor of Psychiatry

w.

Mum

�</text>
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Sister Mary Janice Belen, R.S.M.
Administrator
St. Lawrence Hospital
1210 West Saginaw

Street

Lansing, Hichigan 48914
Dear

Sister

Mary:

Jack Ludatscher was an immigrant physician who joined our
1964 or 1965 as a resident in psychiatry. I knew him for
about a year before I left St. Louis.

staff in
in

some

He was

trained in clinical neurology
studies then in progress.
He was

and we used

his talents

I Eound him sincere, cooperative, and anxious to please.
treating our patients and was able to carry out

capable in

his reaponsibilities reliably.
for

I have no hesitation in recommending him for any position

which he

is

now

qualified.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Ming

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1983

Wammm
!

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immmnmmhmmaum. lfymwishthin,
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‘

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1953

mm
mm
Division of mm Diseases
m.

722

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chfm City, Eﬁumi

mm:
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mummmm Immmmemmymmwa! ;1963.

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�</text>
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&lt;$I

”A.

.

September 19, 1979

"m'l-M‘WI‘WW—vv

WWW'meﬂ-w

Leopold Bellak, M.D.
Bronx Municipal Hospital Center
Bronx, New York
Dear Leo,
Thank you for your informative letter of September in.
I checked my file, and find that the report I submitted as a review of
the role of BCT in schizophrenia is dated July 13, 1977. Since that time,
there have been some additional publications, some noted "in press' have
been published, and what is more important, the attitude to ECT in schizo—
phrenia has crystallized-~ in part, because of the publications, and in
part because of a meeting sponsored by NIMH in February, 1978.

draft will need editing and revising. Some can be
that such an opportunity will be given
us. Otherwise, I regret to say, the publication will be outdated before
it appears in print.
done in

galley,

The

and I do hope

Let
My

me know how we

can

rectify this problem.

regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

�Leopold Bellak, M.D.

August 17, 1977

Albert Einstein College of Medicine
Bronx,

New

York

Dear Leo,
Thank you for your comments on the report, "EST and Other
Somatic Therapies in Schizophrenia".

suggestion regarding page l,is good. Would the following
penicillin therapy successfully replaced fever therapy
for neurosyphilis, populations of misdiagnosed'schizophrenics' disappeared".
This suggestion comes from my experience at Bellevue. I came to learn about
neurosyphilis and psychosis in lean-us, just when one treatment was
replacing another. Fever therapy was used in patients where syphilis was
presumed, even if the findings were unclear (as was true for the use of
ECT). I am only trying to suggest that diagnosis issa difficult
art,
and that as new modalities are developed, we change our criteria of
diagnosis. If the sentence offends, delete it.
be

better:

The

"When

Page 11: "Whether ssuch a sanguine
an improvement.

justified" is
perhaps

therapeutic outlook is

Page 15:”These are a few questions posed by the EST

it is

Ibis sentence

time to reassess the usefulness of

removes the offending phrases.

EST

data;

in schizophrenia.‘

Page 2: The criticism of NIMH is meant to stay. I am chagrined
that the millions of dollars spent by the schizophrenia research branch
are often wasted on psychosocial approached for a syndrome whose principal characteristics are as clear as a brain disorder as are the
characteristics of brain tumors and epilepsy. The discussion of biological
research is largely biochemical and pharmacological, usually of a limited
kind. I mean to be upset by the absence of supported research in therapies
of schizophrenia. I have listened to Loren Masher and his social views
and I fins them particularly weak. Unless you insist that the paragraph
be deleted for political reasons (very sad, if you do) I would prefer
that it remain on page 2. It states a fact which I believe to be accurate

and

it

suggest

is not out of place.
My

thanks for your critique. Are there any additions you would

My

regards.

?

Sincerely yours,
Max

Fink,

M.D.

�Mme-n

w,—

.

—-

—\-.-w

V‘vr'“:

July 16, 1977

w-w-m

anwn’,"'w“f

Dr. Leopold Bellak
Bronx Municipal Hospital
Bronx, New York 10u61
Dear Leo,

Enclosed are two copies of the report, "EST and Other
Spmatic Therapies in Schizophrenia" for the next volume in the
reviews of schizophrenia.

raised not for the
ridiculously small and
in
previous ventures, byt to spell out the
quite unimportant
usual questions of reprints, author's reductions in additional
question of ’royalties'

The

amounts involved, which have been

was

volumes purchased, and complimentary copies of the volume. These
are quite customary, and it is unusual to carry out a venture

without the usual details written. For example, as a gentlemen, I
know that you will supply each author with a fuse copy of the final
volume and 100 reprints of the chapter. Yes ? And that additional
copies of the book can be obtained from the publisher at a 30%
discount ? Yes ? And that royalties will be given to the editor's
favorite charity. Yes ? (Hopefully, the royalties do not go to
the publisher who is making too much already.)
No,

In any case, I assume the above 'usual' conditions apply.
I do not need any subvention for the costs of the article. Yes,

you may have

it

for your

volume as a

gift.

I look forward to seeing the whole; I enjoyed working on

this part.

My

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

�August 3, 1978

Leapold

Ballet,

M.D.

22.Rockvood Drive

Larehnont, N. Y. 10538
Dear Leo:

Enoloeed are some notes as you requested

report in your forthcoming volume
these additions are useful.
My

to update my
I trust

on achiaophrenie.

regards.
Sincerely yours,
Fink, M.D.
Profeeeor of Psychiatry

Mn:

Mszc
Encl.

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                    <text>July 22, l968
Mr. John

J. Bellizzi, Director

Dear Mr.

Bellizzi:

Bureau of Narcotic Control
855 Central Avenue
Albany. New York 12206

is a copy of our Federal Tax Stamp. Class 5 4 and 5 narcotics. The suggestion in your
June 21, that we apply for a class 6 (marijuana)

Enclosed

marijuana and

letter of

does not apply to us since

we

are not millers.

I trust that these registration stamps are sufficient
to comply with the regulations.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>January
ﬁr. John

22 , 1969

J. Bellini

Director, meeau of Narcotic Control
855

Central Avenue

Albany,

New

York 12206

Dear Mr. Bellizzi:
Enclosed

is

an

affidavit mega-ding the supplies of
my office at

depreaaant and stimulatory drugs in

39 Arleigﬁ‘x Road, Great Neck, New York.

position at New York I'i‘edical College , however,
we do have supplies of opiates and marijuana for our
experimcmtal purposes . If the mmlatims require an
inventory of these (huge; , please Wicate the requiremzmtc .
In

“c.”

m-

w-grw

my

wrei-

Sinccnoly yours

,3.“ng

3

ai"

-

”Kr-‘1'!”

5

Max

w
.A

v

:r-v-a;

wan-m-

5-;

r

n:.
L.-

:-

rgrgxfl‘l."

,
u

-H

,
&lt;

I;
«cum

unto-y

mar:-

Fm

0,

NJ).

Professor of Psychiatry

5-»

2‘1?sz

�</text>
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                    <text>ﬂag:

7v3w4/
June 27, 1972

J. Bellisri

Mr. John

Director
Bureau of Narcotic Control
State of how York
Department of Health
84 Holland Avenue
Albany, ﬂew York 12208

hr. Bellizzi:

Dear

I am writing with regsrd to Certificate 2984. issued to the
Psychiatry hrug Addiction Unit st 1901 First Avenue as s Class VI

-Registrent~ﬂethsdone Haintensnce Program.
We

Scientific
(1)

request re-designation as Class VI:

and Medical Research.
We

are not a methadone maintenance

Laboratories for

facility.

treat more patients with methadone as part of their
we also use group therapy, narcotic antagonists
but
psychiatric care,
(cyclazocine, naloxone. 355.), use heroin for experimental purposes,
(2)

and

We

do

test methadols.

hold

we do abide by FDA regulations, for methadone but also
for levomcthsdyl, nsloxone, L-cyclezocine. etc.
While no special regulations apply now. I anticipate that

IND

(3)

Class VI « HIP

will

be

restrictive

broader Class VI: Laboratories
Metropolitan Hospital.

—

and request re~designstion to a
both at 5 East 102nd Street and

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Mex

Hing

�</text>
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                    <text>10 May 1973

Saynour thy, M. D.
Departnnnt or Puyehin&amp;ry
EhrVnrd Madicnl Babool

Fruit

strict

Button, Hassaahusetts 0212h
Dear Seymour:
In submitting the summaries to Dan Freedman for tbs Archives. I haw:
a$taapt¢d to mnet his publication style and find that many references
of the sun—Irv luck tn. last pngn or the c1tn$ion.

references. ﬁbula it be puuaible
I copy of tha rcﬁyped
check
citaﬁion lists for the complete
or
to
your
start
your
t
rutoronco tad couplets those? I: thay art cant to no, I can so. thnt
tbs corroetcd citations got to Lawrcncc Erlbanm and to Dan Friedman.

I

um

tar

Many

enclosing
number

thanka.
Sincerely your»,

an: Fink.

M.

D.

Professor of Payehiatry

“Viﬂvv

Enclosures

�</text>
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                    <text>May

It.
M30

21,

198%

Helen Bellows

Muller

Road

St. Louis. Himmri

W Dr. Bellm£

It is with

gmat pleasure that I appoint

you

to

the Missouri Instimta of Psydziatzy. in tha position of
Research

Scimtist, effective July 1.
I

am

looking forward

1961*.

to having

you join the

Sincemly yours ,
Max

Pink.

Director

N. D.

Staff.

�</text>
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                    <text>May

23.

195:»

Dr. Helen Bellows

Muellar Road
St. Innis. Missouri
le30

Dear Dr. Bellows:

It is with great plasma that I

appoint you to the

Hissmﬁ Institute of Psychiatry, in the position of Research
Scientist, effective July 1, 196%. This appoinmnt is subject
to the rules and mgulatiom of the Division of Mental Diseases
of the State of Nissotmi.

I

am

lodcing forward to having you join the
Sincerely
Max

Fink,

War

yam ,
M. D.

staff.

�</text>
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                    <text>November 8, 1962

Dr. Ira Belmont
Albert Elenstein College of Medicine
Beet Chester Road
konx, New York
Dear Ira:
Enclosed is a letta' from Dr. Robinson regarding the Rorschach report.
pleased that it has received the acceptance of the editors. but find that
they have some questions which require an answer.
I am

Their firet question is one that we have discussed at length and while we
had agreed to report only these findings which were signiﬁcant, I believe this
should be made clear in the text. I know of no theoretical reason why ”psychic
enwizere“ should have the effects measured by these scores. and specifically
with schizophrenics . Do you?
The second question has never come up before and I would be interested

in your comment. Is there some way of analyzing the data anew following

their suggestion?
I have

sent a copy of the letter to Max. If there is some merit in getting
together to discuss this. I plan to be in New York at the meetings between
December 5th and December 8th. If this is not necessary, Iwould be pleased

to hear from you by mail .

Sincerely yours.
MISSOURI INSTITUTE OF PSYCHIATRY

Max Fink, M. D.

MF:aw

Director

one.

Please address correspondence to: 5400 Arsenal Street. St. Louis 39, Missouri

�</text>
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                    <text>O

,r.

ﬁg;

April 9,

196A

Dr. Ira Balaant
Depattmcnt of Rehabilitation

Albert Einutcin
College of Medicine

Esstahostcr ﬁend

New

York,

Dear

Ira:

Haw

and Morris ?ark Arcana
York

I have just read the abstract of your latest report

in the Archives of Gonarsl Psychiatry. I vauld 11k.
to keep up to date in the variaua reports coming from
the Billstda study. and unulé appreciate a few copian
of this reprint when it is available, as well as any
other reporta which may have bean complated.
Sincerely yours.
max

Fink, H.D.

Direator

HFIJb

_,

Mifgéjtmw

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                    <text>-

«nu-mm"

-.v--

May

_&lt;-‘-.—.

Mr. E. H. Belter
The Addiction Center
2000 Domanik Drive

Racine. Wisconsin,
Dear Mr.

14. l970

53404

Belter:

Enclosed are copies of our recent reports on cyclazocine
in the treatment of opiate dependence. I trust these are

helpful.

Sincerely yours,

Max

Fink,

M.D.

Professor of Psychiatry

Mthr
Encl.

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Mr. E. H. Belter
The Addtction Center
2000 Domanik Drive

Racine. Wisconsin,
Dear Mr.
1n

14, 1970

53404

Belter:

Enclosed are copies of our recent reports on cyclazoc1ne
the treatment of opiate dependence. I trust these are

helpful.

Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

MF:hr

Encl.

,

.

Ham-1v

"JV—7r.

«,r'VV"

To

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1","

m..-—.-_-»-...w- W,—

m.‘

e. \e— -. unaware“ .uﬁw—‘u-“emnn’- Y...“ «an m. e: "—wnw—rwv‘“w‘—'ew u.

—.,.

.V

"-‘a. “u. ‘,__.___._..___....._.._...4

May 17 ,

“.7.

.

.4

1976

Dr. Laurette Banter

#23 Ben Oaks Drive

W.

Saverna Park, Maryland

21146

Dear Dr. Bender,
The American Psychiatric Association has established a
Task Force on Convulsive therapy and as a member, I have been

literature for a statement of the efficacy
in a variety of conditions, including the
treatment of childhood psychoses. I have been referred to your
work as evidence of the usefulness of seizures in children and
have found it difficult to find the citations. I would be
grateful for any reprints or reference to published material
that you may have available that may assist in this effort.
asked to review the

and

safety of

EST

Dr. Hegeman was kind enough

she, as do 1, sends her regards.
Many

to give

me

your address and

thanks.
Sincerely yours,
Max Pink, M.D.
Professor of Psychiatry

�</text>
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                    <text>"'W—"“ V"

13',

"

‘

'“

'

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"u

-

'v-

,

x

--:-:n.v;-.r——~m;.sw

lﬂxhir‘lv‘)»

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7W.

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.

3.7.-.- .._.,

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t

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,

June U, 1976

rs
~4-

~11,"

~

mw—r-v

jwu

Laurette Bender,
M23

M.D.

Ben Oaks Drive West

Severna Park, Maryland 2llM6

u
.

‘1r-Zt‘mur

Dear Dr. Bender,
Thank you very much

.v—q

~n-m-w-y.

~wvmﬂ'mww‘1'm-

recent report,"Childhood

for the opportunity to read your

and Adolescent Remissions in Adult

Adjustment in Shock Treated Schizophrenic Patients". It is
clear from this survey that the administration of either metrazole

or electrical seizure therapy did little harm to the subjects, and
perhaps assisted the short term adjustment.

Excepting your studies, we have been unable to find
other adequate examples of treatment in children; yet, the
practice seems widespread, as was demonstrated in the Massachusetts
review of EST in that state in 1973. What is to be done 7 Should
additional studies, of the effect of EST in childhood schizophrenia,
be encouraged ? Should the studies be comparisons with drug therapy
alone, or should there be drug and other therapies as comparison groups

many

a

I fear that the APA Task Force will have a knotty problem
in attempting to place EST in childhood schizophrenia in proper
perspective. On behalf of the Task Force, I thank you for the
chance to read your reports. I trust I may share the draft sent
me with the others on the project.

P.

mm

'wv-Wmm

My

best regards.
Sincerely yours,

unsung-weep

.u-Aww—v-

«wr-

W"'l&lt;:m‘&lt;a"'—wiwr

Fwnnm‘v'

A,

Fink, M.D.
Professor of Psychiatry
Max

?

�</text>
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                    <text>.,_, ..

ww‘nw—

,

NV

.q...

,

;
g

E

Ref:

72—322

June 26, 1972
Morris B. Bender, M.D.

Professor

Chairman

&amp;

Department of Neurology
Mount Sinai Hospital
100

New

Street and Fifth Avenue
York City 10029

Dear Morris,

the Presidency of the
attended the meetings
It seems like
There are
found
and
discussions
rewarding.
so
of the Association
its
times when I regret that my path for research led me away from the
sure diagnoses in neurology and the clear images of the PEG and the
arteriogram. Surely, the squiggles of the EEG are a far cry from the
images on the x-ray.
But, I am also writing to congratulate you on your address-which was reported to me as a tour de fbrce.To have found an under—
standing of acupuncture in DSS is magnificent, and should the ensuing
research prove your hunch to be correct, it will provide a new impetus
to the research you so ably fostered.

ANA

hope

on your election to
so many years ago that we

Congratulations

I

that

regrets at not attending the meetings in Chicago-- I
will be able to meet again under such favorable conditions.

My

we

My

best regards to Sarah.
Sincerely yours,
Max

P.S. Thinking of the past reminds
Have these been discontinued

me
?

of the

Fink,

M.D.

Israel Strauss lectures--

�</text>
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                    <text>August 29, 1972

Morris B. Bender, M.D.
Professor of Neurology

Mt. Sinai Hospital
New York City

N

Dear Morris,

I very much enjoyed your report on a theory of acupuncture.
I tried to relate what little the popular press describes
about acupuncture to the DSS data, the more I am impressed that DSS
represents a reasonable way to study the process.
The more

of the formation of an NIH committee
enclosed unpublished study. The 1956-1959
quantitative measurements provided a better means of studying D85,
and in 1963-64, when I began to play with a CAT, we designed the
enclosed study to demonstrate the cerebral components of sensory
interaction. We found evidence of interaction in the AEP but could
not relate these changes to reports of extinction of stimuli.
sent

me

to

The announcement

my

The

files for the

exercise does demonstrate a

problem in acupuncture, and

may

be of

way

to study the DSS
you or your committee.

interest to

Good luck in the studies. Perhaps, DSS will yet become
established as the explanation for the"hypnosis' phenomenon which
is now becoming the talk of the psychiatric community.

Sincerely yours,
Max

Fink, M.D.

�</text>
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Dr. Morris 8. Bender

East Shore
Kings

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Point,

New York

ll024

Dear Morris,

It

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I know that your many students will be as
new appointment.
I
that
as
recognition came to you in the form that
gratified
did ~ a rostrum from which you can lead many other young

it

students into neurology and research.

Congratulations and my best wishes for success of your
Department and the New Mt. Sinai School of Medicine. Please
also extend my regards to Sarah.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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April 30. l968
Dr. Morris 8. Bender

East Shore
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Road

Point,

New

York llOZ4

Dear Morris.

It

was a great pleasure to read the announcement of your
I know that your many students will be as
new appointment.
gratified as I that recognition came to you in the form that
did ~ a rostrum from which you can lead many other young

it

students into neurology and research.

Congratulations and my best wishes for success of your
ﬂepartment and the New Mt. Sinai School of Medicine. Please
also extend my regards to Sarah.
Sincerely yours.

“WWWW,~'_F

Fink, M.D.
Professor of Psychiatry

Mex
,....,.

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~

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Department of Neurology

Mt.

Sinai Hospital
City

New York

Dear Morris,

Belatedly, I heard of the birthday party planned for you
Orleans. I regret that I cannotaattend, and trust that Martin will
extend my best wishes in person.on the occasion, as I do now in good
spirit and with all my heart. May you have many more such happy
occasions.
in

New

We have finally moved from Great Neck, to a smaller
home in Nissequoge. Where is Nissequogue, you will ask ? In Suffolk County,
among the horse fanciers and the farms, near the University. But
is
a part of the land that is like Great Neck was soon after the second
World War, quite rural. We have yet to become acclimated (we moved at

it

the end of January) but the opening of University Hospital provided the
needed spur.o I now have an active service in addition to my laboratory and
teaching. When next you come East. let us know and I will be honored and
pleased to show you around.
Have a happy

in sending our best.

birthday and

many more.

Martha

joins

4933’:-

LEAV'F3IWV

Sincerely yours,

WW7"

'

Fxm'm'”

wwwsun

'~

~'

mz-mvwﬂwr

"‘t‘r’v‘ewﬁt-m“

new"

Fink, M.D.
Professor of Psychiatry
Max

me

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                <text>1980 </text>
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                    <text>Febtuuty 13. 1966

Dr. 5. Reagan.»

Clinical Director
waltboto Stata Boayltal

Weathoro. Mass.

Dear Dr. Benjaaau:

Dr. Viola: Sundar D‘s, of ?ak1.:an, has applied to that:
laboratories for tha poaition of a research puyahintriat,
and has indicated you as a tutetcnct.

I vauld be gratctul for

any

infotaatian that

you may bu

able to 31v. nu regurdins Dz. Da:' training, raaesrch

abilities,

and

intcretts.

lubatntotial have placed an anphsaia on clinical
pny¢h1atric rateirch, and I would bu moat incoreltcd in
Dr. Dal' nbtlity to cannunicato 1a a program with out
psychiatric population.

These

Thank you vnty much

for your cooperation.

'

Sincerely yours,

,

-..

4
A

_

yink.
Director

Max
Amwwrﬂu

MF/jb

M.D.

�</text>
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                    <text>May 8 ,

1967

Dr. Willian P. Bemjmin, Secretary
Nassau Hampsychiatric Society, Inc.

1200 Stwart Avenue
Garden City, New York 11533

Bill,

Dear

New York, I have asked
m inBranch
of the American
District
Psychiatric Association in order to participate in their

As my

principal office is

to join the

New

York County

program.

While I was a member of both societies before having
for Missouri, I find now that the rules of the APAche this
double membership impossible and I am, themfom, requesting
a transfer fmn the Nassau (Now York) District Branch to the
NwYorkCountyDistrictBranchofthoAPA. Iwouldbe

gratefulifymmdaignﬂumlowdfmandsemmn
Sonnet, Roan 460, New York,
to Dr. Sidmy Malitz at 11 West

New

York 10026, Secretary

of the

‘42

New

York

District Branch.

I do not low if it is possible to officially cmtimc
in the Nassau Nmpsychiatric Society, but I would like very
rmch to cmtinue my association unofficially 3131 look fomm
to oontinuim to attcm the public meetings of the society.
My

best wishes.
Sincerely yours ,
Fink, 11.1).
Professor of Psychiatry

Max

MP:kp

cc: Dr. Jay Stanton

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                  <elementText elementTextId="105177">
                    <text>My 31, 1968

13:».

Ely

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Ivan Emmett

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18. Box

Indianapolis, Indiana
Ivan.

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                    <text>hpril 23.

1969

Dr. Ivan F. Bennett
Illly Research Laboratories

The

Eli Lilly and

Company

Indianapolis. Indiana

46206

Dear Ivan.
I regret that our paper "d-cyéloserlne 1n the Therapy of
Psychosis“ has not been published. The draft sent to you has

not been prepared for publication.
Thank you

for referring

Dr. Thomas

pleased to answer any questions that he
My

to us.

may

and I would be

have.

best regards.
Sincerely yours,
Fink, h.D.
Professor of Psychiatry

Max

Mszp
.-

.m.

.‘Twnwuwav

a.7,.....~.--v.«worm—l

,‘

,.l.

�</text>
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                    <text>‘SV'vv-wavw.

w. wu—
—

‘1'".xw7m.17,m,w~~ﬂs—urrww-.,,~,.__

..V

1...“

m."-

n ruv

5".‘vml'ww

October 6, 1969
Dr. Ivan Bennett

Lilly Research Laboratories
Eli Lilly and Company
Indianapolis, Indiana 46206

The

Dear Ivan,

After many years, we have been prompted to comylete
the enclosed report, ”§;Cycloserine Therapy of Psychosis
by Symptom Provocation” and it has been accepted by Fritz
Freyhan for Compaeheneive Psychiatng.
In reviewing this data, we were once again impressed
in large doses, has useful CNS activity Seromycin,
that
useful as a stimulant for depressive and withdrawn subjects,

particularly those in state hospitals. Perhaps, further
studies

can be stimulated.

Thank you

for the Supplies.
Sincerely yours,
i'iax Fink,

f‘goDI

Professor of Psychiatry

MF:kp

cc:

T.

Itil

.-». -,

n nmswrw—wr—

,

a.”

�</text>
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                    <text>March

Dr. Ivan Bennett
Ely Lilly Company

Indianapolis, Indiana

4,

1970

46206

Dear Ivan,
I am pleased to enclose a copy of the report ”d~Cycloserine
Therapy of Psychosis by Symptom Provocation", which resultad

studies in Missouri.
application has merit.

from the
ﬂy

As

you can

tell,

we

think that this

best regards.
Sincerely yours,
Fink, .M.D.
Professor of Psychiatry

Max

Mszp
ENC .

�</text>
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                    <text>June 9, 1970
Dr. Ivan Bennett

Eli Lilly Research Laboratories
Indianapolis, Indiana 46206
Dear Ivan,

Enclosed is a copy of a letter from the FDA requesting
since I have
information as to the formulation of methadone, studies
in
just filed an IND to permit us to continue our
opiate dependence.

written authorization to refer to the
manufacturer's formulation date for methadone as requested
in their letter.
May

I request a

Many

thanks.
Sincerely yours,
Fink, Md).
Professor of Psychiatry

Max

-

MF:kt

enc .

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                    <text>Deco-bar 6, 1971

Dr. Ivsn Bennott
Ely Lilly Company

Indianapolis, Indiana

46206

Dear Ivan;
Enclosed or. copies at my requeot to Karo: Bentonnn
reply. If you can support our request, perhaps you would
sand those on to Avram Gold-coin with your con-onto.

and hi5

Many

thanks.
Sincornly youro.
Max Fink, M.D.
Professor of Psychiatry

MI:13

Inc.

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                    <text>my 25,

1965

Mutt
Why
Box 285

Dr. Inn F.
Ely Lilly and
RR

18,

Indianapolis 2», Indium

Dear Ivan:

AMWago.synssooiataDr. Itilsndlbeamintomstadina
adatailsdsxmryofhis
Wuiththisdmg. Inhislottor,ho
indioatesthatymhadmdammmtrialsindamnicsmimpimic
momtmportmamingoyolosarim

Immmmmmm

patients without "any success."

_

Attintimtmtlwmtotow Ialsosentalattcrtotm
Imtakin;tholibnrtyof'

'

WWtofElyuuyamcmany.
swing yooaoopyoftlutlnttsr,wabsliavettatIshmldmvawr-ittm

andanyinformtion
ittoyoudimotly.
ﬂamintsmtadinthisoawomd.
males
woold

that you can

be appreciated. Specifically,om
available to m
motors to the qmstims in our Mirror? Also. amid you
amt-12o your ominous with clinic sdxioophmnio pationts, for this is

you provide us with

thegrmpthatwahavenostmdilyavaﬂablatous.

memfswmonths,wohambogun

meithsomeofour

the lines of intmive omtnl
patients
We me: have pa
3 receiving ministration!»
stimulation.
system
mm
ofhixhdosasoflsn,orbitsnandohlormzinmorhighdosesofatmpim.
Inaaohofﬂusstmmtsmmattawtingtoaltormoambmlrhyﬁm
which do not appear to alter with tho usual psychotropic micatim. The
savers long tom aohizoptumio

patientsselmdformssnmymmmmtohnwmmmdiﬁahls
alplumytm. ﬂammabilityofoyolomimtoimahighvoltaga
slow wave activity intemts us, and so would wider- the minimum
ofthisoorpomdtowrlmgumpatientstoinmmhmindunges
omoomitmt behavioral
and
hopefully

charges.

Imuldappmiatoyouroomta, andyowassistamo inundortakin;

this project.

Sim‘wsly yams,
ﬂax Fink,

M. D.

Professor of Psychiatry

Mfﬂcp

co:

up. 11:11

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                    <text>June 15, 1965

Dr. Ivm P. Bamatt

Ely Lilly mo Coweny
RR

18, Box 285

Indianapolis 2n, Indiana
Dear Ivan:
'mank you very much for your letter of Jme it, and the
detailed information regarding your experiences with oyoloserine.
After reading all the data, my associates and I have become
partimlarly interested in an opportunity for clinical trials
with oyoloaerina in a group of severe mentally ill. Toe effects
in altariag bmin {mod-m over a prolonged period which you
noted and which otinre have reported, and which have generally
been mgatded as side effects, are precisely the focus of our
intranet. We would like to induce prolonged changes in brain
fmotim in these patients.

For this reason and following the report of Dr. Vitek,we
.pmicularly interested in a trial of l-cyoloserine if
that is available. If not, the remit: mixture also seem to be

would be

effective.

to
we

able to make supplies of oyoloeerine available
m, and provide the necessary FDA olearmoe? If not, whom may
cmtaot at Lilly Laboratories for sud: a oollabomtim?
Would you be

Many thanks

for your assistance.
Sincerely yours ,
Hex

Fink,

PLD.

Professor of Psychiatry

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                    <text>September 16 , 1965

Dr. Ivan F. Bennett
The Lilly Research Laboratories

Eli Lilly and
RR

18, Box 285

Company

Indianapolis , Indiana

Dear Ivan:

I have returned from my vacatim and we have selected a
of patients for our cycloserine study. We have not yet
received a lumber from the FDA, but, if I recall correctly, the
filing of the application is sufficieat.
If this is so, then I would appreciate receiving a supply
of oycloserine for this experimtal use . We would plan to
adninister up to one gram daily for a. period of four weeks in
number

about ten subjects.

adequate.

A

supply of about #00 gram would be quite

In addition, the laboratory would like to prepare a standard
rather than emptying one of the capsules and running the risk
of the filler interfering is it possible to obtain a supply of

and

pure oonpound, approximately 200 milligram?
Thank you very mob

for your co-operation.
Sincemly yours ,
Pink, rm.
Professor of Psychiatry

Max

MF:kp

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                    <text>March 17, 1968

Mutt

Dr. Ivan F.
Lilly Research [abomtm'ies
Eli Lilly and cowany

m

Indianapolis 5. Indima

Mar Ivan,

MmfwmlamI'ochhn.
was

Nahumleted

observatims with Serwwin in ten patimts and are now in the
of summarizing ourremlts. I hollow these chasm-—
timetobeofmintmstmdwindiscuastrnm udthyou

in

Him.
My

best regards.
Sixmmly yours,
ﬂax Fink, H.D.

Profeasor of Psychiatxy

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                    <text>April 7,

1966

amt!

We:
M

Dr. Ivan P.
The Lilly Research
Eli Lilly and
RR

18,

Box 285

Indianapolis, Indiana
[has Ivan,

Iwrymchenjoyadmlmminmshingtm,mdwhile

mm

Idonottmnkmtfurmrsmdmuichloseﬁmssa
its possibls
mmpeutic agent in
m
mud.
Wemnow
masamnuslstimlantstﬂlimﬂgmsus.
collatingmdatacfmmsmdymdfindtmtwmm
I mariting to ask you" clarification.
omfussd in one
regard.

mums; to the

Physicians

miﬂmrmnmrmbm.
is listed as Massimo-3»
_

91M;

Win
‘mimdwithiaadszid

madman,

i

.

We

5.3

had intmpmted the

mismmimnmas indicatingthat itwasthu 2)me
m-mieleswittenhyeaorgom
MappemdinSemmycin.
also list his use of D form. In our dismissim, I believe you
the ﬁxture.
Dbefam

indisated that Sammycin

is

Canyouclsﬂfymichfommhwebeenming? A150,]:
mmsplmdﬁmpmdmtdesmiptimmdmuld mquestymr
sendingms Wrifiﬂ: is wailable.
Myﬁwrks.
Sincemly yams ,
Max

Pink,

1-1.1).

Professor 0! Psychiatry

�</text>
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                    <text>October 4. 1966

Dr .
Thu

Eli.

Ivan

r.

Bennett

Lilly Rescue): Laboratories
Lilly and Company

Indianapolis . Indiana

D.” IV“

m‘ﬁ'ﬂ’u-

«v

——

7w"

Wrzm—m.

M14”

cyclonortno data was owned on 5/18/66.
boon:- uprouod with tho
viewing the data as symptom
possibility
provocation. and hold up the report until 6 months
follow-up. This will ho «20:910th in Hovubor and
tho rcport should follow noon.
Hy

Tho

nuoohtuofand I
“ﬂunk you

w-

w

rink. NJ).
Professor of Psychiatry

ﬂax

4.

Ivy-gar”

,

unvwm—W

tor your mutant .
smcoroly your: .

W”.

‘g'v,

I

”ﬂap

�</text>
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                    <text>mmrm mm

_

"5'

‘1'-

August 22, 1972

WWn—v—vmwm—u-wvwrvm—wW"

,.

w-

IV“ Fe Bum.tt, NJ).
ﬂedicsl Research Division
The Lilly Research Laboratories
Eli Lilly and Coapany
Indianapolis, Indiana 66206
Dear Ivan:
Your letter regarding citations of methefrone and nethajade
as trade names for levonsthadyl aroused some anxiety. I checked my
files and than called Herck.

(1) Math-Jade
(2)
E

g

'

Hethefroae

to another

is,

as you suggest. a formulation of methadone.

is not a

Merck trademark. It seems
compound, unrelated to levo-ethadyl.

to belong

Thank you for bringing this to my attention. I believe it
the JANA staff that added the trade naaes to our article. and
should they wish to correct their records, I am sending a copy of
this note to the Editor, Ir. Hussey.

was

Sincerely yours,
Fink. M.D.
Professor of rsyohistry

Hex

HF:ig

cc: Rush Eussay, ﬁ.D.

‘

�</text>
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                    <text>November 23, 1961;

Dr. 1). Boats

of Program Committee
Qmim
C.

I.

N.P.

lhivemitats—Nerverﬂclinik
Sohwabaohmlage, 10

Ek-langen‘, Germany

Dear Dieter:
The

time reports

from the laboratories from the

Missouri Institute of Psychiatry presented at the latest
mating of the C.I.N.P. , are enclosed. I regret the few
weeks delay, but it seemed mm important to bring each
report up to date. I trust that this action will not delay
the publication date of the volume, and I look forward to

its

appearance early

in 1%.

It would be regetable if this volume has th
delay similar to the one of two years ago. For that
on,
my associates and I have carefully read these. reports md
,-

.

‘

shalloooperatewithyouas fullyasweoantopmduoe this

next volume most expeditiously.

I

'

was

looked forward

to seeing you in Washington, but

sorry that you did not attend the Psychophysiology

matings.

My

best regards.
Sincerely yours,
Max

Fink,

Director

mfgls

enclosures

M.D.

‘

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                    <text>January 9, 196“

Eur matter:

mm

I should like ta participate in the 196% C.I.N.P.
for this rem, I an admitting the maimed abstract. "mug
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this cmiwtim with m fallwship.
Tum is sending separately a report of his clinical work
for your mimmtim.
and

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Wheatwistmsférﬂmﬁw'iw.
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�</text>
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                    <text>February 5. 196$
Dr. Diets; Bantu

Unlversitsts—ﬂetvsnkltalk
Schusbsohsnlsgs-IO

852 Etlsngsn, on

Vest Germany

Des: Dieter:

It is

with great pleasure that I accept your kind invitation to
1n the-Collegian Intsrnstionsls Heuropsyohophsrsscolostcua 1n Ssptcabsr. I should be plosssd to describs ths
tssction of nauroloptit and sotideptousiva drugs from the stsnd~
point of clinical EEG.

pittieipltc

During the post nook, tho asllsy proofs of the "Bibliography of
EEG and Human PsychOphsruscolosy“, Supplomsnt #23 of the EEG
Journal, arrived and we are now checking it.

I hsvo also sgreod with Dr. ﬁstsan to writs so overview of those

600 stticlss. This will be published with tho Bibliography. snd
I'hOPG to hove 1t svsilsbls for him by the first of Hatch. Thus,
by tho sooner, tho Bibltosrsphy sad the overview should be in the

hands of the

participants. This will provide part of tho bssio

for the ditcnsoton.

Plssse accept my thanks for your consideration.
to participating in tho programs in September.

and

I look forward

Bincstaly yours,
Ha: Pink. [‘1st

Director

ur:5b

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                    <text>May

22. 1966

Dr. victor Bantu
Chairman, Progrnn Counictoa
C. I. R. P.

Univursitats-ﬂirvnnkltntk
Sahvubaehanlago 10

Brlnnscn. Geruany

Dnar‘niotcr:

I haw. rccaivnd.tho list of the working groups in czpcrtucntsl
anutophyctulogy and clinteal naurophysiology. and I In delight~
ad with both. I would like. havevnr, to £sk that you includa
the aunt of Turan 1:11 in the ptncl on clinleal nourophyatology,
as I think that Turin has axe-ptlonal naporiuncn Ind ra-nrkablo
judgnnnc in this ficld. I 3130 noted that your own nuns was
not included and I do hop. that you will be ab]. to participatc
during tha clinical naurophyitology diaeuscions.

I II writing to

Dr. Bradley, auggcnttng that
city he invited as my guest to the
In vxaw of his special capericnne, I believe he vuuld bu

sop:racc1y,

Dr. Charles Shiatsu of Iowa
CIHP.

an inportant gartictyant in tha puma! on expcrinantal anatowould be possible to includa his
phyaiology and kept that
annu in th:: list.

it

I an watking hard
status you at the

on my presunaacian, and
and of August.

I

106k forward

sincerely yours,
NIX

rink.

airmeeor

III/3b

HID.

to

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                    <text>October, 20 , 1965

Dr. Dieter Bente

.

Mamiteta—Nemklinik

8:31me
Gummy
Emma,

10

Bear Dieter:
Bath Ttmm and

join you and our

I

I regret very and: our inability to

my frienm

in the mating in

Nuremberg.

mow the meetings will be very interesting and
forward to reading the reports early next year.

We

look

It has been more than a mmth since we spoke in Salzburg
about the premtatims fun this laboratory at the GIMP in
Bimingwn. At that time you had indicated that you mld
provide a
for these thme papers md I am

maﬁa“;

yet
clarification: of the stemmtmhmnot
of these reports .
please answer- me pramtly?

arithmnmtommindym
I

hepe your matings held

prom

pmvided.

all the

pm

mivede

Would you

which the

Sincerely ymrs ,
Fink, 14.1).
Professor of Psychiatry

Max

�</text>
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                    <text>August 29, 1969

Dieter Bente
Universitat3~Nervenklinik
Dr.

Schwabachanlage 10

Erlangen, Germany
Dear Dieter:

is our

letter.
though
I had not heard from you, I anticipate
that
will
you
he in the States for the EEG meetings. I look forward
to seeing you in San Diego and, in View of your
extensive experience in EEG and psychiatry, I would
be delighted if you could Join us.
My best regards.
Sincerely yours,
Enclosed

follow—up

Max

Fink,

Even

M.D.

Professor of Psychiatry
MF:kp

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                    <text>October 20, 1969
Dr. Dieter Bente
"
Oberarzt der Universitats-Nervenklinik
Schwabachanlage 10
8520 Erlangen
Bayern , Germany

Dear Dieter:

It was kind of you to invite our participation in the
of the German CINP. The topic ”Drug Abuse
symposium
next
and Addiction! is of particular interest to us and perhaps
we should participate. You may know that we have been

studying narcotic antagonists in the treatment of opiate
dependence for more than three years and a presentation
on the subject ”Narcotic Antagonists in the Study and Therapy
of Opiate Dependence" would permit a review of our experience
with cyclazocine, naloxone, tybamate and methadone. Given the
time, we would also discuss the EEG changes and heroin challenges.
In

this report,

and Arthur Zaks.

I do not know

my

co-authors will be Drs. Alfred

M.

Freedman

if

marijuana and cannabis have become
a problem in Germany, but if you wish, Dr. Freedman would
consider a report on our experimental studies of marijuana
and THC ("Experimental Studies of Marijuana and THC in
Volunteers“).
I

trust this reaches

you in time.

Our meeting on September 25, on EEG and psychiatry was
quite interesting and I believe successful. The group did

not wish to organize a Berger Society as yet, but did think
that we should meet again, probably on the occasion of the
meeting of the World Psychiatric Association in 1971. To
that end, I have agreed to try to arrange such a symposium
and have already written to the organizers of the meeting.
My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

Mszp

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                  <elementText elementTextId="103161">
                    <text>I‘ 1

l

A

s ‘

‘w—w—m

"mm

...mw.w—..‘—q——_—uwmztwmw—n—w.

"w“-..n. w-V..7.w...,v..,

—..~.'——.«--

.7

.7

w

_

_

,

_.

.

vows—1

&lt;-

Advil-1115!!!

w;

Rovomber 13, 1969

Dr. Dieter Bente
Universitats-Nervenklinlk
University of Erlangen

Schwabachanlage

Erlangen,

10

West Germany 8520

Dieter,

Dear

regret the necassity of sending the night
from the presentation. 'When we first
withdrawing
letter
received your invitation, neither Dr. Freedman nor I were
really aware that this was our holiday weekend. We both
have sons away in college and for this holiday our children
are coming back. Thanksgiving has always been a family
holiday and we both feel the necessity of staying home.
I very much

Harijuana, however, has become an important problem
in this country, and from what I hear, In Europe also.
I am trying to arrange a session on marijuana at the GIMP
in Prague. We are carrying out active studies in New York
and I am also planning a study in Athens late in the spring.
Perhaps there will be another occasion on which we can present
our data on marijuana in Europe.
My

best wishes for

a successful symposium.

Sincerely yours,
Fink, 3.9.
Professor cf Psychiatry

Max

Mszp

�</text>
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                    <text>.n- w...— rv... J...

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                    <text>Fohroory a, 1965
Dr. Joooph 0. Benton
Dopartnout of Rohobllltotlon Modloino
State ﬂolvorolty of low York
650 Clotkoon Awoouo
Brooklyn, Row York 11203
Door Joo:

It was": plooonro to moot you on the Washington Railroad Stotlon
during tho roooo: bllozoxd.' Barboro Floh had I bod o ploooont rounlon
during that trip. It would- be fitting to hovo a 20th Aonlvoroory Gloss
Rouoloo and your oussootlon to hold it o: tho now York Unlvoroity Club
to o roosoooblo coo. to: tho oonvonlonoo of those of on who oro ovoy
from How

York. pothopo tho nootin; could ho hold in ooojunotlon with o
ootloool oodlool oootlog. I might ougsoo: tho: tho Anorioon Psychlotrle
Aooooloclon lo oooelo; during tho {trot nook of May in now York City.

It

hos boon

2

1/2 yooro olnoo 1

During tho: tioo. chin rooooroh

lot:

now York

for Klooourt.

ond training contor. tho Min-ourl
Institute of Poychtotry, boo boon octobllohod; Pottonto (150)
hovo boon odolttod to the words, ood warlouo opoeloliood laborotorloo
laoludlog tho cooputor cannot. onimol. hlcohomlotry, ood phoruoooloxy
lobototorloo. and o rooooroh library oro oqulppod and oporotlns.
It was our doolro to oohlovo Eull ooddonlo olflllotlon. and as of

January 1. tho Inotitoco to now tho nov Doporenoot of Poyohloery of
tho uolvorolcy of Hiooourl School of Hodlclao to 8:. Louis. ‘Tho
Uhlvorolty to planning o third uodlool school in thto clay in tho
futuxo. and this doportoont to tho first of that oontor.

My oppolotaoo: now to ?ro£oooor of Poyohlotry, and Hood. Dlvlolon
of Rooootoh of the Inoclcuto. Rowovor. Coaching ooolsnnonto ore light,
so I hovo oolncolnod my oppolntoou: oo nooootoh Protoooor ot Wishingcon

Unlvoroley School of

thtolno

with tholr nodicol otudonto.

whoro

I onjoy

ow

tooohlng ooolgnnonto

�studits at. pttnarily dovocud to the physiological and
psychological Alpacas a! drug tharapy for tha sovgru manually 111.
1 haw. continund my interns: in ninettooncophnlography and haw.
rtcnntly publiahod a number of article: and a bibliography of "EEG
and Human Psychophar-acoloxy."
My

I look forward to siting

you

in Int. spring.
Sincernly.

rink. ﬁ.D.
Profoopor of Paychintry

Max

H3:ju

�</text>
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                    <text>September 2, 1969
Dr. T.H. Bonainger
Naval Modical Research
Bethesda, Maryland

Institute

Dear Dr. Benzingcr,

I have read the two articles in the latest issuc of the JANA
describing the measurement of tomperatlre using tympanic thermometry
with great interest. The figure in the companion article, describing
the changes in temperature with anesthetics is particularly relevant
to our studies, which are devoted to measurement of changes in EEG
during the intravenous administration of psychoactive drugs.

articles indicate that tympanic thermometry is safe
figures, the measurements are made in minutes. I would
like to ask if the equipment is available commercially; and from whom.
The

and from the

Does the instrumentation allow for;measuremcnta of changes occurring
within 2-3 minutes 7

Thank you.

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

mf/

�</text>
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                    <text>F

._...

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,

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.

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October 10, 1971

9

..

V

mm..-

“rum—v

Dr. John Bergen
Chairman, Membership Committee

Society of Biological Psychiatry

WW

Dear John,

I am pleased to nominate Dr. Michael Alan Taylor
in the Society of Biological Psychiatryﬁlﬂinner,_uith
membership
for
Dr. Robert Levine, of the 1969 award of the Society, his work needs

little

introductionéj

resident physician, he was most industrious and
undertook independent research into the concomitants of post—partum
schizophrenia. Demonstrating that the sex of the offspring bore
a significant relation to illness in the mother, he subsequently
demonstrated that hormonal effects operated concurrently with the
ataractic properties of drugs-— a conclusion derived from his data.
As a

During his residency, also, he carried out independent
of the lactate infusion test for anxiety neurosis, confirming

verification
the work of Pitts

and McClure.

Since returning from military service, he has established
of
independent studies at Metropolitan Hospital, in
a variety

anxiety and in schizlphrenia.
I

am

pleased to

recommend him

for

membership.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>V'W'wn-ﬂ‘mmwm

ywr'w

M.

.

y.

”7, w. -w. “NV—”Wrm‘w-vr:w—.,w~.w-—m w.-.._.mw—W~am—ﬂ-Tv—w7......» m‘\-r‘——— wee—W.
»

w. ‘

7-...r__-.._ _,_, .7-.__.._._ _._r,_. . s..._... W
‘

w

V

October 10, 1971

Dr. John Bergen
Chairman
Membership Committee

Society of Biological Psychiatry
Dear John,

I am pleased to nominate Dr. Richard
in the Society of Biological Psychiatry.

Abrams

for

membership

Dr. Abrams is a (nil time member of the research staff
of this Department and has been an active leader in our studies of
Convulsive therapy both during his residency training and as
a memebr of the clinical and teaching staff.

After completing one year as resident, he served his
tour of military duty. During that time, he undertook independent
reasearch into the variety of modifications of electroconvulsive
therapy, including multiple treatments in one session and unilateral
electrode placements. His work served to establish the parameters of
these treatments, and he is now responsible for this clinical program
in the Department.

is studying the effects of penicillamine
role of lactate in the precipitation of

In addition, he

in schizophrenia

and the

anxiety.

He

is an industrious

of the scientific

and serious worker, an avid reader
and an excellent teacher. I am pleased
membership in our Society.

literature,

to recommend him for

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

,

�</text>
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warm-u-

,

’Iﬂ‘l‘er'ﬁlnyi:u

a

.

‘7

-__.... ..., “my ,,
,

”nu” , in

»,—.W,W.—mw. 7.--.

December 12, 1975

Jchn R. Bergen. Ph.D.
wcrceoter Foundation for
Exporimsntal Biolcgy
shravcbury. Hasuachunctts Olshs

Thc

Dcar John,

I am pleased to nominate Dr. George Heninger fur
aaibcrnhip in the Society for Biological Psychiatry. I have
known of his work for more than ten years and have followed
his cloctrophyniologic atudicn with intcrcst. He is a capable
investigator and has contributed much to our understanding of
tho electrophysiclcgy of psychoactive drugs.
His curriculum vitae

I

command him

is attached.

for maubcrship.
Sincerely yours,
Fink, M.D.
Frofeasor of Psychiatry
Max

MF/mr

Enc.

»

.v .

7“.er—

�</text>
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                    <text>May

Dr.

2a, 1965

Mow Barger

Director of Bdwatim and Chief Psychologist

Mental Health Division

Stats

Omgon

Board

of Omtml

Salem, Oregon 97310

Dear manor-gar:

Wyou
intro
amimmmdarﬂuauapioesofﬂxammntal
waltz}: Division.
would be
oonvonimt for me
to

make

from

youvory mob for your invitation to participato
to plan
mot
It
the. presentation on Friday, June 25. 1965-.

ammts

I

would appmciata your making
for my flight
St. Louis to Portland for Thumday awning. leaving tho

mtmntripviaSananciaoo.Itwou1dbeholpfulifyou
wild make msarvatima for Thursday evening for no and if

you

madpmvidamwiﬁaﬁninatmtimaastohowtogattoﬂn

loom site on Friday zooming.

I ananclooing a

copy

of my

miculunvitaaandmyphommaayoumquaamd.
ItvmldbotnlpfuliflhadablaokboaxdandaZxZ

,

slide projector available.
Thank you very web for your invitatim and I look formrd

vtomnatingyou.

Sincerely yours.
Mm!

Mfzjm

'

Emlosma

PM. NJ).

meoaaor of Psychiatry
‘

�</text>
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                    <text>June 28, 1965

Dr. Andrew Berger

Dimotor of Education and Chief Psychologist
Health Division
Gaga: Stat. Board of Central

mm

Salem, Omgm 97310
Dear Dr. Berger:

I

would

mg to

take this apportmity to thank you for

m

I enjoyed my
invitatim, md to tell you hm
visit. I was very much inspmsged with Dr. miss and the
numbers of the staff whom I met. I emjoyed the tour of the

your kind

I told you, the questions and the mats
cf the pmctitiomm were musually cogent and instructive
to me. If mum of‘the audianca glemed as much as I did
in ﬁgs confemme, I believe you have had a successful

hospital.

As

session.

Dr. Irwin was very kind and shaved me much of Portland.
toumd the radical 861ml, and a rumor of the midential
districts. I fomd the city delightful.

We

I

am

enclosing the variom receipts which you

and a statement of

to

my

mmSan szcisco.
an

night in

the

evening and

Thmk you very man

may need

possible
ewes.
was
overto
stay
necessary
it

incidmtal

It was not

for your invitation.
Sinmmly yams.
Fink, I'M).
m
Professor of Psydxiatry

�Fink, 14.1).
Hissom'i Instituta of Paydaiatzy
5000 Arsenal Strut
St. Louis, Missouri 63139
Max

T0:

Omgm State Board of Control

Jam

25

Jme

25

June 25

Hotel: Partland
San Francisco

3

Bmakfast

Dinar

-

8.00
10.00
2.00
7.00

'

Taxi expenses in St. Innis

$

3.00
3.50
33.50

�</text>
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                    <text>September

1%, 1965

Dr. Andxw Ber-gar
,

Dimetor of Bducatim
Oregon State Board of Control
Salem, Oregon 93710

Dear Dr. Berger:

I have received mismumemnt for my trawl expenses to

the State of
on July 29.
Since

it

Oregon

in the

amt

of $27.50. This

was

that time, than: has been no additional mimbumemnt,
lectumahip provided for m
to check your records?

was my mdamtanmg that the
hommriwn. Would you be so kind as

and

Sincerely yours ,
Max

Fink, Md).

Professor of Psychiatry

Hfzkp

,

received

�</text>
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                    <text>February 10, 1969
Dr. Frank Borgat
Walloon Laboratorioo

Croodall.

How

Joraoy

Door Frank,

In reading tho latent icons of Drug Research Roporto,
I notod the report of your lecture at ﬂoorge Washington University.
ond if tho roport to correct, I woulﬂ like to concur in your opinion.
For many years I have boon among those confused by the usual animal
pharmacologic data submitted to investigators to the basis for the
selection of drug: to: trial. Repeatedly. I have notod that the
characteristics proolatmod by one pharmacologtat as the basin for the
choice of a drug for trial. are disregarded or interpreted differently
by another.

role of

The

You know

EEG

that

measures in

man

we

have boon actively investigating the

as the basis for classifying

new

classification of cyclotoclno, fenfluramine, thiothixooo.

drugs.

nod piooxnpin by those mothoda have been countatent with the

eventual clinical observations. Perhaps the tin. has come to
investigato those data 1nd roporta systematically by an industrial
laboratory such as your own.
In any case, the report

our observatiooa.

(if oorroot) lo consistent with
slncaroly yours,
Fink, N.D.
Professor of Payohiatry

Max

of]

�</text>
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                    <text>7453*04353
30

Fred Andcrmann, u.n.
Montraal Neurological
3801 Untvcrsity

Mbnttatl, P.Q.

strnet

January

197&amp;

Institute

CANADA

Dear Dr. Andtrnann:

I

pleased to sponsor tha report ”EEG and Behavior Effects
of Naltraxonc in Man.” which in baits submitted for presentation
to the Bastcrn EEG Mbctinx by my £023.: coworkor, Jan Volavkn,
am

Md).

work

‘

I hope that he will have an opportunity to present this
in the next matting.

Sincerely yours,
Fink, M.D.
Profcsnor of Psychiatry

Max

MF/cis

cc: J. Volavka,

M.D.

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                    <text>7483-03083

18 January 1974

Beckman—New

Dimensions

2500 Harbor Boulevard

Fullerton, California

92634

Gentlemen:
have received the announcement of the New Dimensions
audio—vioual technical programs. We are interested
of
series
EEG—l,
"Electronics for EEG Technicians."
in
we

appreciate the opportunity to review this series
prior to entering our purchase order. Should it be possible,
please have your representative call me at the University.
we

would

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF/cis

�</text>
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1
w”

m

whvﬂfuJJ'

August 15, 1969
Mr. P. Bergmans,

President
Eleevier Publishing Company
Jan van Galenstrant 335

P. O. Box 211

Amsterdam, The Netherlands
Dear Mr. Bergmana:

letter of August 5, has clarified the subscriptions to
Journal very well. The addresses are correct. I wish to
thank you for your cooperation.

the

Your

EEG

sincerely yours,
Fink, M.D.
Professor of Paychietry
Max

�</text>
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                    <text>July 28,
Hr. P. Bergnsns

Elsevier Publishing

1969

Co.

Amsterdam, Ratherisnds
Dear Mr. Bergmans,

I regret bothering you with a small problce, regsrding
twice in
subscriptions to the EEG Journal, but I have written
I;
would
the past few months and have not received an answer. I
of my oubscriptiong, to the
appreciete clarification of the state
Journal.

Through the New York Medical College, I have renewed one
nobocriotioo which is addressed to my home at
39

Arleigh

Great ﬂeck,

Road
New

I have also recently ordered

addressed to

my

lsborstory:
9r.

York

11021

1 second

subscription,

Hex Fink

Depertnent of Psychiatry,

5 Esst 102 Street
Rev York City, ﬁ.Y. 10029

New

York Medical Col.

subscription to my home is up to date, for I have
received vol. 27 #1 (July) last week.
The

subscription to
the January issue (vol.
The

office, which use to have started
26) has never been instituted.

my

vith

If the
apprecistc your checking your files.
incomplete,
records
the
or
for,
paid
second subscription was not
make
adjustments.
the
and
necessary
I will
plessc advise me
I

would

have requested our purchasing department
EEG Journal
to send you so order for a connicte file of the
arrive

Incidentally,

we

vol. 1 for Iy laboratory;
early in August.
from

Thank you

and

this order will

for your assistance.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>June 22, 1971
Dr. Lawrence Bergner
Health Services Administration
185 Worth

New

Street

York, New York 10013

Dear Dr. Bergner:

In continuing our program of study of the role of narcotic
antagonists in opiate dependence, we are interested in assessing
the clinical use of a new narcotic antagonist, .-5050. In animal
trials. it is 8-10x as potent (on a mg basis) as naloxone with a
duration that is slightly longer. In contrast to the manufacturing
problems of naloxone, we have been assured by the manufacturer that
adequate supplies for clinical purposes can be made.
We

believe clinical

trials

with

M~5050

should be undertaken.

filed
toxicity studies adequate to
meet our standards prior to such trials. To file an IND we require
animal toxicology data. There are not available from either the
An IND

must be

and pro—clinical

manufacturer or his U.S. representatives.

have obtained proposals for the safety evaluation of M~5050
meet our needs, including single oral and intravenous
studies in rats, intravenous studies in dogs, oral administration
We

sufficient to
for

13 weeks to rats and to monkeys, from various laboratories.
principal proposals are from the Food and Drug Research
Laboratories of Maspeth, L.I. , and Woodard Research Corporation
of Herndon, Virginia.

two

The

To carry out these studies. prepare and file an IND, prepare
the necessary protocols, and undertake the initial human trials
using the heroin ”challenge” model will require funds for:

(1)
(2)

(3)

Animal toxicology

$31,500
7,500
Nursing and psychiatric 4,500

Consulting costs
support

$

43,500

This study will require 18-24 weeks for the animal toxicology;

for the

IND; and 10—12 weeks

for the

initial

6

weeks

heroin challenge data.

�Dr. Bergner

June 22, 1971

—2-

We trust these data
will be sufficient to provide the basis
for definitive clinical trials in opiate dependent
for trials in developing a long-acting formulation. subjects, and

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>January 23, 195:;

Miss Marilyn Borhnd
University of Rashester
7

Box 5592

c

Rochester 20,

,

how York

Inthetwowosks sinosyowvisithom,1hovo owlomdo

umber of possibilities oonooming your appointment. Dru Garfield
indicated that he would not be available for such of the author
period, and mmttsd that he wou1d not be in a position to supervisa a stucbnt this owner.
I modo a similar inquiry to Other mothers of the staff of
the hospital, and found that no provision has as yet been made for
owner o1pimnt. In Ergo measure, this results from the striagency in fundo which has generally restricted the State to appointmoms on a- more pomxaxmt basis (say. It is rcg; isomooion, howover,
that if you wish to partioiwts in thepsychological program of the
hospital on a volmtoar hosis, that this could be amused.
'

1 summit

such as you how

that I

am

masons.

umbh to mom a position available to you
A,

Goodludcinyowotudiesgmi

mm,
gum
1.

H. D.

�</text>
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                    <text>May 15 ,

‘7.""Yp'f‘

"1w.-

w

venr—m

-

'
M

Ir.

Joseph

555

Prospect Place

1967

A. Beulah

TheJewishHospitalomeoklyn
Brooklyn,

New

,

,
97M
£97

York 11238

war-v;

Dear Joe,

.
‘4

'.
'

aft"-

155‘an

W“

”(UM-.947!“

A,

I have read the appendix to your research grant with a great
deal of interest and find that the associates at Columbia University
are most sophisticated in the analysis of EEG sigmls. Their
euphasis on power spectral density is logical. but it is probably
the more expensive way of handling the problem which you face.
It seems to me that the initial approximations for your work are
no different than our initial appmximatdnns and for these, period
analysis is faster and much less expensive. We lave already
developed a variety of methods of Using the period analytic
output to characterize the patterns in the EEG and these might
be useful in detennining the changes which you anticipate in
your animals.

.

1;

”'3!

"musing-5V“!

.

5w

(shag-z.»

4;»1—yﬂ'n‘t‘;

My second tMught has to do with the idea of a library of
tapes. This is indeed a good idea, altmugh I wonder if saving
the digital tape is the best way to save the data. It does
man, that any analyses you wish to undertake must he done in
laboratories which cam mad that tape. My om predilection is
to save the analog information. However, this may be too

expensive.

Incidentally, I found the enclosed article in the Medical
section of the J.A.M.A. recently and am sending it to you.
The differences in the two records described in this note are
probably masurable by period analysis.
News

laboratory shmld be in operation by September and we
to have you and your associates visit us with
the assurance that we will ooopmte in any way that we can.
My

would be pleased

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>w A: ”w“. ;.,._

.

-m.——Wzﬁ'm WWW-MVWww»

”ﬂaw—w-

m-“ m..-.- v.‘mm~._ﬂv

V

- .m.“ . .7 .w. w...........,.,

VFW H- WWW... .7. l”...V.W—.—.

March 29, 1975

Julian

L. Barman, M.D.

Department of Pediatrics

The Chicago Medical School
2020 West Ogden Avenue

Chicago,

Illinois

60612

Dear Dr. Berman,
Thank you for the kind invitation to be considered for
the position of Chairman of the Department of Psychiatry. I regret
that I cannot face relocation again, and cannot apply for this
positéon.

If he is not already on your list, you may wish to
consider Charles Shagass, M.D. of Temple University. He is an outstanding teacher and researcher, a political leader (President of
the American Psychopathological Association and the Society for
Biological Psychiatry). and well liked by his colleagues.
Sincerely yours,
.

n

imw'm

Fink, M.D.
Professor of Psychiatry

Max

w

v

�</text>
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                    <text>wvw‘

Ref: 72-316N

June 27, 1972
Robert

M.

Derman, M.D.

Veteran's Administration Hospital
New York City 10010
Dear Dr. Derman,

Enclosed

consultant at the

vitae.

is a completed application for the position of

V.A.

in

New

York, and a copy of

my

curriculum

In February, I was appointed consultant to the V.A. in
Montrose, and I have requested Dr. Harris of Montrose to send a
your attention.
letter indicating that this was indeed accomplished,to
V.A.
allow
the
to transfer
will
the
that
appointment
earlier
I trust
the appointment to New York, and avoid the extra effort in process-

ing.

Today, I spoke to Sam Kaim who indicated that he had
received support from SAODAP for the collaborative studies, but had
not received answers to his request for additional supplies of

levomethadyl.

My

thanks for your

invitation.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>Maw—WW,

w.*m,wm\w_

"em—,m—m»..u—.w—....,..

g, ﬂﬂﬁ"

u

r"‘("—."Yulrvaw

3—H-”

‘

Alvin 8. Bernetein, Ph.D.
Associate Professor
State University of New York
Downstate Medioal Center
Department or Payohiatry
hso Glarkson Awenue

Brooklyl,
Dear Dr.

New

York 11203

Bernstein,

quentifioation method is preferable to eyeballing,
outline in your letter of August 6 seems quite
the
sophisticated. I think the method will show changes in brain funcof your system, you
tion, should such changes occur. As a test and
closure and hyper—
could establish the effects or eye opening
show big changes in
should
two
thst
simple
procedures
ventilation,
EEG. If these are shown, then the method any is useful. If these
are not evident, then I dug-eat you try some other system.
a research
It is not possible to predict the actions ofmovement
behave
Brownian
or
like
seem
to
committee
they
grant
the random discharges from outer space, but the methods you outline
are not 'gross or simple—minded'.
and

Any

method you

-

Good

'

luck!
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF/mr

Yum” .F—m—n—w‘wﬂpr...“

�</text>
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                    <text>a

vv—w-u

«my—mum ~—- v—wpumw—ww.

V” qr... “r4m1"¢&lt;)lr'leA-'Wr.“wA w

mum.

.-

“an,“ _. .71 awn-was.

March
Mr.

w

-

N's-n-vW-‘wvv

an. 1,." w.

.

,

e

V

___...., -

an. ”a-..“ w...“ .v. w_,w .v-..,.1_-v _. a...“ ,7 .7

l3, I970

Jack Bernsteln

Boston State Hospital
Boston, Massachusetts 02l24
Dear Mr. Bernsteln:

Separately we are returnlng the sample tape. As Mr. lrwln
dlscussed wlth you. your tape recorder ls fully competable wlth
ours, except that there may be some I problem In the footage counter.
would appreclate your sendlng
To obvlate any footage dlfflculty,
a paper playback, marked In footage wlth the next tape so that
we can compare the footage meters.
A

EEG

problem ls the proper settlng of the galns of the
For those channels recorded on tape, please set the

crltlcal

machlne.

ampllfler so that

50 uv

'

l4

mm

pen

deflectlon.

suggest that as soon as you have some EEG material from
a subject on tape that you send It and the playback for us to
check agaln.
May

I

am also encloslng the output of the sectlon on zen medltatlon.
Because the sectlons are short It ls dlfflcult to Interpret. Epochs
ll-lB show llttle change from the llstlng, but epochs l9-27 may be
dlfterent,‘13g;, a decrease ln amplltude and In verlablllty, an
lncrease ln average frequency and ln fast frequencles, wlth a
decrease ln delta.
I

Slncerely yours.
may

.

w...

":41"

own-WW}

w-rmqvwv

s-

1v‘-Inr‘

Max

Flnk,

M.D.

Professor of Psychlatry
Mszp

Wmv

V

,

,,

,

�</text>
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                    <text>August 1, 1969
Dr. Stephen B. Bernstein
Prom Head, ECIEUResearch Brand:
Psychophumoolog
National Institute of Mental Health
susu Wismin Avenue
(navy (Jase, Maryland 20203
Dear an. Bonntein:

gentWkamWﬁmeuﬂt.
iaaomﬁnmtimofstudieabe atliﬂlsideﬁospital
in "DB md Hum: Payctqhmmﬂogy"

The

(PH—13358) and

(mm-1962) (PH 927, 2715, 2092, and at the Miwcﬁri Institute
of Psyd'tiatry (1962—1966) (Hi 08517.11380 11381) and in

ofde

is focused m
and in this
mgax'diamlativelymiqxeinﬂxempmgrun. curfew
Nut York (1966-

quartitative

EEG

) (Mi-13003).

aspects

'Ihe pmgram

maddictsmdmalvolmmmtmoﬂmunmualfea‘nms.

Ihwewmdm.mmtoviaitmﬂdssmm,to

pmvidem oppwumitymdimaﬂmdhecﬁamwemm
mtakhm.1m.11dbepleasedifymwmldjoinhim,mﬂ

useﬂmoooaaimtobecmaaoquaintod.1tmstwecmmt

befmtlufallnmhofnnatirga.

Sincerely yours,
Max

Pink,

M.D.

meesaar of

1mm

Psydmiatry

�</text>
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                    <text>Hovambar 31, 1959

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...m W's: ‘ ,. "upg-. —~mzn~wmwu¢ror v-ry'r-m-h—rmmnmwm"

May

18, 1970

Dr. Stephen Bernstein
ECDEU Program, N.I.M.H.
5454 Wisconsin Avenue
Chevy Chase, Maryland

Dear Dr. Bernstein,

In preparation for the ECDEU meeting, I have read the
ECDE! studies finished and reported June 1969 to May,
of
the
report
1970. One one of our studies, that of doxepincchlordiazeponide is

listed.
w—

at least

period:
~vv-1Wmmau—m-ww

3

In discussing

this with

additional reports,

Dr. Simeon, he assures me

Form 22, were

that

submitted during this

Thiothixene in anxiety/depression

AHR~1900

in schizophrenia

Ketipremine-imipramine in depression.

Copies of those

to vou.

reports are enclosed,

if

the originals failed to get

rm"

In my recent telephone conversation, I indicated that I
intended to request a continuation of the program, MH—13358, "EEG and
Human Psychopharmacology" in two parts-— one focussed on EEG and another
on ECDEU in juveniles. The ECDEU application, "Psychopharmacology of
Juvenile Behavior Disorders" is now at our Research Committee and
should be in Washington by June 1.

not meet the June

1

The EEG program

application will

deadline, but will be submitted soon thereafter.

I look forward to seeing you in Boston.
Sincerely yours,
Max

Fink,

M-D.

Professor of Psychiatry

mf/

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V

July 6, 1970
Dr. Stephen B. Bernstein, Program Head
Early Clinical Drug Evaluation Unit
Psychopharmacology Research Branch
National Institute of Mental Health
5454 Wisconsin Avenue
Chevy Chase, Maryland 20015
Dear Steve,

Enclosed is a contribution for the ECDEU Intercom. If it
is too long, I will be glad to edit it. Our programs are, as
you see, quite extensive, and perhaps this report should be
divided over a few issues.

In thinking of this summary. and

perhaps an

article

can be

my

recent cell to you,

written in Intercom to describe the

populations available to each unit. It would give us a better
view of the basis for the results discussed.
Another topic of interest is the prison methodology for
early phase I studies - who does it, where and how?
Thanks for the invitation to contribute, and my best wishes
for the success of this endeavor.

Sincerely yours.
Fink, H.D.
Professor of Psychiatry

Max

MF:kt

ﬂxn'géa

_

r.

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                    <text>"Mm. aw ﬁw-yp'w

7:

rwa ‘nvxm'vgfv

—,.

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. w

Maura-V

ii.l'm"~'.~J-WVW.W“1§&amp; w-mr xu

—'Inv1,-s')W—‘¢1v

October 23, 1970
Dear Steve,

Enclosed is my reply to the population inquiry. In addition
to a classification by populations, phase of drug study emphasized,
perhaps a classification of special interests and services might
be useful, such as the units focussed on clinical toxicology,

international collaborative studies, ophthalmology

EEG.

Effective this month, Dr. Jovan

and EKG, and

Simeon has

staff of the Missouri Institute of Psychiatry

rejoined the

and he has been
replaced in my programs by Dr. Richard Abrams. Dr. Abrams has been
a research fellow for more than 2 years and has focussed on studies
of ECT, memory mechanisms and recently the treatment of alcoholism
with an alcohol antagonist and sch120phrenia with heavy metal
chelating agents. I would be pleased if he were placed on the ECDEU
mailing lists, at the above address.
Many

thanks.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry
mf/

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5 «was.
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                    <text>«-

"xv’ﬂy'rm‘l mum-warp»:«Irv-warn.

v stoma-navy

Nirvana-slurr-wuw-srv-n .r

x w» mm

wow-w

“Mm'xr‘wﬁyv

2

{Inner

nunvv-w-msrv»

w-v- ‘wvnm-rmxmwvw

-

v-v

-

v

unmvr

two-w

w

"ma”‘ﬁw’WAWVW—www

October 5, 1970
Dr. Stephen Bernstein
Psychopharmacology Research Branch
National Institute of Mental Health
5454 Wisconsin
Chevy Chase, Maryland 20015
Dear Steve,

Separately I am sending you a dozen each of recent reprints
published with the support of MH-l3358, as requested in the recent
ECDEU

Intercom.

Incidentally, you are to be congratulated
issues. My staff and I read these issues with
may

on the

much

first

two

interest.

There is one problem. recentty brought to my attention that
be discussed by the ECDEU investigators with some profit, that

of the compensation of subjects injured in our studies. I am
enclosing a thoughtful article from a recent issue of Science.
This has become particularly important as more investigators are
assessing drugs in normal subjects (B. Goldstein, T. Iti., L. Goldstein
and C. Pfeiffer, myself); in ambulatory outpatients (Rickels, Wheatley.
Engelhardt); and in children and adolescents (Engelhardt, Connors. Fish,
Simeon) - papulstions which provide unique ethical considerations.
The issue was once discussed at length by the Clinical Committee
(1961 or 1962) but no action was taken. Perhaps, a review is
indicated at this time.
My

best regards.
Sincerely yours,
Has Fink, M.D.

Professor of Psychiatry

HF:kt

encs: Havighurst: Science,

10

July

70

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v

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                    <text>April 17, 1971
Dr. Stephen Bernstein, M.D.
ECDEUwFRB

NIEh\

Chevy Chase, Maryland

Dear

Steve,

I would be most pleased to present a summary of the
present status of the EEG progile analysis study program,
with a focus on the application to ECDEU missions.
As I will be attending the conference, you
the presentation to suit your program needs.

will put

may

schedule

I do not have a formal presentation worked out, but
one together and send you a copy before the meeting.
My

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Mex

mf/

WW

-

n
xv

-m'r“~"'ﬁw"m:~t’w.v

...;J

�</text>
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                    <text>4_

.

.

VV‘qnt'V‘V-n'

June

‘1,

1985

Alfred Bertagnoll, M.D.
Catholic Medical Center
100 McGregor Street
Manchester, NH 03102
Dear Dr. Bertagnoll,
Dr. T. Meehan was a staff psychiatrist at the V.A. Hospital in Northport a
few years ago. During that time, ECT was administered at the V.A. under the
general supervision of consultants from the Department of Psychiatry of SUNY at
Stony Brook. Before Dr. Meehan joined the staff, my associate Dr. Richard Abrams
had set up the unit, and after he left, I supervised it.
During Dr. Meehan's service at the V.A., he carried out treatments in this
and
was considered sufficiently adept that he continued to treat patients for a
unit,
I
time. cannot recall a time when I observed his treatments.
To the best of my recollection, Dr. Meehan did not have any formal
in
training convulsive therapy at this University. The 'training' was passed on from

one therapist to the next. Nor can I recall the length of time that he 'ran' the ECT
unit, since such assignment was the responsibility of the clinical director, Dr.
Robert Derman.
As you well know, there is no formal accrediting process for ECT in the
United States. It was a recommendation of the American Psychiatric Association
Task Force that a continuing committee on ECT be established at the APA, to
develop guidelines for training; but the leaders of the APA have seen fit not to
create such a committee since the report was accepted in 1978. in this climate,
judgement as to Dr. Meehan's credentials must be based on your own criteria.

Sincerely yours,
Max Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>Hounnbcr 23, 1971

Mr. Karat Bosteman

Deputy Director
Division of Narcotic Addiction
&amp;

Drug Abuse

ﬁlﬂh

5600 Fishers Lane
Rockville, Maryland 20852

Dear Karst:
have been invited to participate in the Fourth
National Conference on ﬁethadone Treatment in San Francisco
in January. Dr. Ivan Bennett has asked that we present our
experiences with the antagonists and 1~alpha methadol. I
am writing to ask support for one investigator to attend
We

this meeting.

The

is

principal support for research for opiate

from the stata of ﬂow York. Last week the
commission cancollcd tho oxpcnditure of all travel funds,
making attendance at this stating unfaasible for us.

dependence

IIIth of

Ho

would

b: gratoful for financial support for

IV

staff to attend this routing.

Hy

beat with...
Sinccroly yours,
22:: Pink,

5.».

Professor of Psychiatry
83:13

8

�</text>
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                  <elementText elementTextId="100946">
                    <text>must a,

Barbuda:

Mar

1963

Hotel

77% Wisemsin Avenue

Bethesda, Maryland
Gentlemen :

I m plmming to attend a Clinical Cmmittee

mating

I

would

singlo

and October 1, 1963.

on September

30‘

like to
for

a Mewatim for a

room

make

Septazeber 29,130., and October

1.. Please hold for late arrival as I will
probably be arriving on M Flight 208.

I wmld

appreciating confirmation of

mamtim.

mark you.

this

Sincerely .
:A

m.

v

vy

"ru-n'

‘7uu:.:,

.&gt;.~V)'IK.-—'

w
»—1

r-

v:
-.

,.
a

‘
‘

ﬂg‘wa‘auwwwz-Mm

fork

Max

Fink.

Dimctm‘

M. D.

�</text>
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Ramadan
77'40

Mote}:

20 , 1963

Haul

Winmin AW

act-mam. Maryland

Gontlem:
Please cancel

saptewar

my

mewatim for a single

29. 36. and October 1. 1963.

mom

far

farmy inmvmim madyminmis
Hemsmy
matter.
Yam-s

truly

m
M.
Dimctor
80

NO

Do

�</text>
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                    <text>October 13,

In

Town Bethesdan Motor

Wisconsin Avenue
Bethesda, Maryland

196’4

Hotel

77140

Dear

for

Sirs:
Max

Enclosed is a check for $9.00 for late
Fink, M.D. for evening of October lath.

Sincerely yours,
Max

Fink,

Director-

mf/ls
enc.

M.D.

arrival

�</text>
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                    <text>May 25, 1989

Dr. Thomas Bewley
Senior Lecturer
Department of Addictive Behavior
St. George's Hospital Medical School
London SW17
England, United Kingdom

Dear Tom,
What a delightful review! Your review of SPYCATCHER as a study in
alcohol consumption said so much that should be said, in an engaging manner, that
read and re—read it. I am writing to congratulate you on a fine job.

Alcohol abuse is so common in our population that it is a feature of fully
half our admissions. Similarly benzodiazepine use is a feature of our middle aged
patients.
In any case, your review was excellent, and l congratulate you on a fine

analysis of modern political leadership.
My

best regards.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry

P.S. It was good seeing you in‘ Brighton. When next you come to New York, would
you let me know? i would like my associates to meet you.
.

1

�</text>
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                    <text>July 28,
Congressman

M.

1970

Biaggi

of Representatives

House

Washington, D.C.

Attention:

Mr.

Peter Ilchuk

Dear Congressman Biaggi:
In response to the telephone request of Mr. Ilchuk, I an
pleased to enclose a copy of a summary "Narcotic Antagonists
in Opiate Dependence”. The meeting was held on June 4, 1970
and was attended by the principal research scientists working
in narcotic antagonists.
They concluded that continued studies of antagonists are
important, particularly as they represent the principal, logical
treatment method for opiate dependence.

There is need for a more coordinated approach for

study.

this

Should you be interested in additional information, I would
suggest that you inquire of Dr. Bertrum Brown, the Director of the
National Institute of Mental Health, Dr. Peter Grey of the Vera
Institute (who has done an intensive study on this problem for
Mayor Lindsey in the spring), Dr. Henry Brill, Director of Pilgrim
State Hospital (who recommended the support and encouragement
which we are now receiving from the New York State Narcotic
Addiction Control Commission), Richard Severo or Joseph Lelyveld
of the New York Times, both of whom have worked on the problem,
or any of the scientists listed as attending the meeting. It
may be useful for you, on behalf of the Congress to carry on
a more public investigation of this interesting and potentially

very useful treatment of opiate dependence.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MP

:kt

611C.

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                    <text>a.“ &gt;y'v"

November 23, 1970

Congressman Mario Biaggi
House of Representatives
Washington, D.C.
Dear Congressman Biaggi:

During the past few months, one of your assistants has
inquired as to our progress in developing a useful opiate
antagonist treatment for heroin addiction. On each occasion,
I indicated that there was no need for additional funds.

I now have two proposals for studies which are
in developing a long acting narcotic antagonist as a necessary
in opiate dependence, with budgets of $400,000 a year.prophylactic
At a recent educational session

Scheuer expressed an

for physicians,

Congressman
making

interest in obtaining assistance in

methadone treatment more readily available to the addicts of the
My associates and I are both willing and able to
assist
in this program, using the medical practitioners as methadone
therapists, under prevailing Federal and medical guidelines.
we suggested that such an effort focussed on an imuediate
”solution"
would be of interest chiefly if it provided a basis for the
deveIOpment of a prophylactic approach.

Bronx.

It

may be

their impact

apprOpriate to discuss these proposals, particularly

on your

constituents.

Sincerely yours,
Vita}!

Fink ’

:4. D u

Professor of Psychiatry
MF:kt

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                    <text>July 1.

1966

R. G. Bickford, H. D.

Mayo EEG
Mayo

Laboratory

Clinic

Rochootor, Minnesota

Door Reg:

is o copy of my publication list. A: I read tho titles.
I find that thorn are fifteen in which EEG data are a major part
of tho report. Since I do not know the scrum that you hovo found,
I on studio; the complete list for your use.

Enclosed

Rotoronco No. 78 is our bibliography which is now in press and
for which I hurt already received the proofs. The referoocoo are
olroady on cards and I would be glad to send you either a complete
dock or a print-oat. or if you with to have this on tape, ind sup—
ply on with a tape, I will be glad to havo it put in tape format.

In any tone, I believe you would find this collection helpful to

round out your ﬁwio index.

If that: in

”

kn“.

any other way

that I

may

be of help to you, ploase

Sincerely yours,
Fink,
Director

Max

MP/jb

M. D.

let

�</text>
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                    <text>wmnr

.m-

'1

-"?~-':“

awn»;

'I‘R-VJV'Q

\-

w'I-na-

~

~ "l'VzH

.-

-

.‘r'.r“--3v".\

u

'wm ,

“-1“... sun r

nr'iw‘“ .3...

-

-'r"o'"7" .. an:

‘

ava- "mgr-~-

:.~-~.:.~.&lt;

7:.

.

WWIdlIb‘MK’u‘K'

ww.

'IA" vuw-«.uwv:=r

December 2, 1968
Dr. Reginald Bickford

Mayo

Clinic

Rochester, Minnesota

Dear Reg,

I

pleased that IBM has indicated a willingness to provide
for the 1969 meeting in San Diego. To provide an
Opportunity for our programs, I am attaching a capy of the
configuration of components with which our 1800 is equipped.
It is my understanding that they will provide this machine
if requested.
an

IBM

am

1800

I suggest that

you write to Dr. Wayne Jostrand, Marketing
Medical
Services, 475 Northern Blvd., Great Neck,
Representative,
New York 11021, indicating the time and place of the 1969 meeting,
and your willingness to exhibit this machine.
May

Perhaps, an announcement in the next newsletter from the
Committee on Arrangements as well as memoranda to the EEG Journal
and Trace may provide you with other workers in the field who may
wish to demonstrate their programs. As an initial guess I would
suggest you contact Ernst Rodin at the Lafayette Clinic, Niel Burch
in Houston, Walter Christ in Chapel Hill, and Bernard Salsburg in
Tulane.

I trust this is helpful.
Sincerely yours,
Fink, M.ﬂ.
Professor of Psychiatry

Max

MF:kp

-

w

.

-.

�</text>
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                    <text>April 10.
Dr. Reginald

a. Eickfnrd

University of California.

1969

San Bingo.

School of undicino
oopartment of neurosciences

La

Jolla. California

92037

Dear Reg.

ﬂesnite much effort on my part. we have been unable to
provide the support noccssary for the exhibition in San Diego.
I regret that we will not be able to demonstrate our EEG

analytic

programs

for psychonhnrmacology.

I

trust this will

not affect the other demonstrations on the 1800. However, since
the New York office of 18M and our sales representative
(Dr. Wayne Jostrand) is making the arrangements for tho equip~
went. I would ask that you advise him of the development.
The

list

of demonstrations is

an impressive one and I

look forward to attending the Congress.

Incidentally.

my

best wishes

on your new

apptintnent.

Sincerely yours.
Fink. M.B.
Professor of Psychiatry

Max

nmp
cc:

ﬁr. Ernst Rodin

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                    <text>Juiy 31, 1968
Dr. John Biei

Aldrich Chemicai
2371 N. 30th

Company.

Street

Inc.

Miiwaukee. Wisconsin
Dear Dr. Biei:

It was a pieasure to renew an oid acquaintance and
piaased to ask you to provide us with 3 grams of
tetrahydrocannabinoI-A-I (or 9). For our purposes. we wouId
prefer to have this amount made up in ampuies containing
I am

20 mg.each.

We possess Certificate No. 2191 from the Narcotic Control
Bureau and are equipped to carry out research of marijuana as
approved both by the State of New York and the Federai Bureau

of Narcotics.
As

bid which

soon as a

price is determined,

I can submit

I wouId

to our Administrator.

Good iuck and thank you

appreciate

for your assistance.
Sincereiy yours.
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

a

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                    <text>July 31,
Dr. John Biel

Aldrich Chemical
2371 N. 30th

Company,

Street

1968

Inc.

Milwaukee, Wisconsin
Dear Dr. Biel:

It

pleasure to renew an old acquaintance and
ask you to provide us with 3 grams of
to
pleased
tetrahydrocannabinol-A-l (or 9). For our purposes. we would
prefer to have this amount made up in ampules containing
I am

was a

20 mg.each.

Ne possess Certificate No. 2l9l from the Narcotic Control
Bureau and are equipped to carry out research of marijuana as
approved both by the State of New York and the Federal Bureau

of Narcotics.

As soon as a price is determined, I would appreciate a
bid which I can submit to our Administrator.

Good luck and thank you

for your assistance.
Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>June 24, 1966

Philip Biernacki
Street
La: Anxales 7. California

Mt.

235 What 22nd

Dost

?hil:

Would you

please arrange for

and assortod

If

you

Gene

Xattaan to pick up one whcel
one of our analyzers?

parts for raplaccmnnt in

will confirm your

firming purchase order.

minimum

pricc, I will send

you a con-

Sincerely yours,
Fink,
Director

Max

MF/jb

M. D.

�</text>
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                    <text>3;. -

April 9.‘1964
Rev. Felix Bicstek, 3.3.
Director of Fieldwork

School of Social work
Loyola University
800 North Michigan Avenue
Chicago, lllinoia
Door Father Biostek:

of Tampa has applied for position
rouaaroh
workot
aocial
at this Inititute, and has
as
submitted your namo as reference.

Mr. Roland G. Mbinott

This

Institute is a

newly created tosearch and

training

center of; tho Division of Mental Diseases of Missouri.
We have tooontly developed study programs in tho treat»
especially those whom
ill,
psychosis”. In the

moot of the chronic mentally
we
W!

call "therapy resistant

worker who

program,

participation of a social
has an intorest in visiting tho homes of our

are anxious to

have the

staff with
regarding the social conditions which

patients

and providing the

prolonged hospitalization.

some

may

information

contribute to

would be grateful for any information that you may
give no regarding Mr. Heinert'a capacities to undertake

I

iodopendeot rosoorch in the area outlined above, his

floxibility

kinda of

and

possibly. intorast in carrying out the

visits required

by

this pragram,

gestions togardiog his personality
get along with hia coawotkers.

Thank you very much

and

and any sug-

his ability to

for your congeration.
Sinooroly yours,
"33 Pink. NJ}.

Director

HF/jb

.13 ,

�</text>
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                    <text>7683-00183
2

John E. Overall, Ph.D.

January 1974

,

Departmont of Neurology and Psychiatry
The University of Texas Mbdical Branch
Galveston, Texas 77550
Door John:

if

Thank you for the reprints. I would be grateful, however,
you chango the address to which you send them to:

Department of Psychiatry
School of Medicine
Health Sciences Canter

State University of
Stony Brook,

New

York
York 11790.
New

at

Stony Brook

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF/cis

�</text>
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                    <text>20 March 1974

Dr. mad. Garner

M.

Klinilche Porodhung

Enrrmaan

Hoaropsyahopharmnkologie

Scharinz

AG

55
65 03 11

D—l BERLIK

Postinch
GERHARY

Dear Wernar:

Dr.

covur,
work.

I

Itil
am

asked mn~tc send you puma narcan. Under sepnrate
sanding you 10 ampules, as you requastod.

You may

prefer to as: pure naloxona

I will be glad to supply that if

you used.

With

powder

you'will

for

any syatamatic

tell

as

how much

best regards,
Sincaraly youts,
Max Fink. M.D.
Professor of Psychiatry

MF/cis

�</text>
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                    <text>Of

College

Physicians

C?

Surgeons of Columbia University

DEPARTMENT OF PSYCHIATRY
Donald F. Klein, M.D.

‘

New York, N. Y. 10032
722 West 168th Street
(212) 960-2307

Professor of Psychiatry

December 22, 1987

Mrs. Edward

M.

Bigler

Doubling Road
Greenwich, CT @6830
40

Dear Mrs.

Bigler:

Delighted to hear that Tom is doing so well.
With regard to the panel on the Phil Donahue Show, I would be pleased
to join it. However, I must point out that I am not really a
national expert on ECT but rather on medication. My old boss, Max
Fink, M.D., who is Professor of Psychiatry at State University of New

at Stony Brook, is an international authority on ECT and
I think he would be an excellent person for
your panel.
York

extremely well spoken.

has recently told me that he has seen a number of patients
somewhat like your son who have an atypical schizophrenia where
had worked in the face of substantial drug resistance.
He

Cordially,
”,7

/I/

/7

‘1’

0K/wxfx
Donald F.

Klein,

dcd
bcc:

Max
"'

Fink
.3

M.D.

ECT

�</text>
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