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                  <text>Hirah 24, 1965

at.

Sol

caliber:

Psychophnrnmaalogy Sorviaa Canes:

Hationll Sink Building
Baehcsdn, Maryland

Ban: 8918

I haw. read aha tulcarch plan on daprcnnion dated February, 1966,
and find
vary staining. I havn a few aouncnta. howuvor, and I
an sharing thcao with yuu Ia thlt tuna of an. «nastionu which any
can. up &amp;e the committoa wanting will be anticlpntcd.

it

with ttgard to thc rutearch plan itsalf, l helluva that it would
ha adviaahla to spaeifianlly annwnr the tallowing queaciaa. tau
ggxdlng pxevioun ttcntnant (pug. 5). Whan tbs raenrd 1ndi¢atou
thit Eh. patlanma will be kept of! inzi~dcpraslancn far 72 heart.
ﬂhﬁt action will b. union for those gatianta aénitted to the
honpital receiving andlcatian from a pravious yraetitianer? What
about gallant! who rceaivnd EC! in the days or sash. practding
aduitaionl (in ch. Billsido study, v: arbitrarily unclndod all
paniantu who haﬁ rgcnivud andicttion and EC? within thrua wank:
of rafcrtnl. (Thin was un arbitrary daciulon and I know at an
natlsinctory data to support this action).

administration af chlorpronasinc in do... up to 600 m3. will
carry with it in anal paients overt rigidity :nd Parkinsoniam.
In our :tudy, w. ttied : nunbcr of sntl-Parkinsonlnn taunts and
ﬂ! concludud that thc aoncnrrent administratian of procyclidcnc
would prevent ch. P:rkintonian fantares. w. publiahad this in
on: at Jonathan's ballutins. On plgl 7. you indicate that :11
undiaation will bu diauontinnad at the and of th¢ 5th Hack.
This should be dang in gradunl fgshian bécauua w! observad Gn'
plcannn: $16: offcets when thit wet damn suddenly.
The

Thu-c thrcc adamant: axe thc only significnnt one: that I unnt
to make abuut thc prcponal itlnlf. I would like to auggont thtt
you add to your list of Inference: eonanrning imipranina being
supcriot to placcbo that: anclotod. which tufluc: ch: work don:
at Hillsidn Hoapital. On page 2, you rcvicw aha various plaeabo

�Dr. Sol Goldberg
3-24-66

Fag.

Two

controlled stud1¢c and eonnludc that auch caudtcl hawu no: r.»
united in useful interlacing canccrning ch: :ypan a! daptasaad
p:t1¢n:n ruopondin; ta tn. drug. I an tsking ch; liberty of
analocins an early draft at my study at Billstda, in which VI
dcacrthcd eh: ru¢poud¢:n-1n that papalcuiou. It may bu unntnl
ca rcvicw this taper: an tha basis for Ialazciou of can; at
the rating acnlaa «blah will b: applied in this study program.
_

I might angst-t that tuna of eke differencaa in the 13 controllad
double blind study 110:: may ha relazgé to such Sanding nattaru
a: dosagc, duration and number: of aubjnatn. In the pat: 21w weeks
I h¢vu baa» tavidwlag tbs EEG ahcngau iadueed by variant drug: an&amp;
it has haca an uynopannr to tutltxa that non- nun summarise eat:
in a vary annnrt£Vt way «van though ch. actual nuuburn tnrolvnd
It. fav. A rcvttv of thus. 13 studio! may 31?: a aannwhnt dtt*

tar-n: piatura.

my

best rogards.
Sinccruly yours,
max

Fink. E.D.

bircctar
xiv/3b

cc: Br. Jonathan Cola

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              <text>1964 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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