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                  <text>Muff-Ki»)

December 27.. 1963
Dr. Dom Clyde

Bicmou‘ic Laboratory
University of mm
250 Bird
Coral Gables '16, Florida

W

Door Deon:

First, let me tell you how ranch I enjoyed my visit and the course.
than, I havo gone over mob of tho Hillside data with a fresh View,
I am inclined now to mite another ropwt on tho EEG data. The compo
*

L

Simon

-

and

was

ospocially rewarding to

me

since

we had data.

low

to both of us to discuss.

it. Separately, I am sending you the tape with the full Hillsido
data. Attached is the mpblom timber index and a sample write-out page.
more om two listings on the tape- the first by patinnt; the oecond, bypmblom number. 111: mlo smote will indiootc the format. Code for
mining data in 9999.

thlemo Ill-.11} are the specially mated "drug—mitive" scoloo
mooted by the Hillside staff; 15 in not on those tapes no it was available
in 50 pntionto only; 30-32 an individual EEG band data
(3, 3.5, n.0, n.5, 5.0, 5.5. 6.0. 6.5, 7.0, 8.0)
(9, 10, ll. 12. 13.5, 15, 18.5. 18, 20, 22.5)
tho original data.
(25, 27.5, 30. as);

we

2. I havo examined the various write—onto of our studios using
discriminant ﬁmotion, and find none comparing ochizonhonieo vs. otMr
on
data. If we wish to add to the present question as. to
another schizophmnics do have EEG patterns different from other mortally
ill, w my approach the Hillside Hospital sample no a wall collected ample.
Pro-data for each of the fivo hando (Prob. 62, #1 ~ 5) and total sum
(Pmb.62 96); or the 2:. hxdividml bonds (Pmb 30-32) are tho EEG datn to be

Winn

to do this analysis?
We do have the covariance data for tho total grcup.tho
and tho others, comparing tho effects of placebo, ﬂmoino mud imi
compared.

Do

you wish

3mm

�Ir.

Dem Clyde

Page

the

Decanter 27, 1963

effects, reflected in the two Erotica and the toteste (see data page
copied, attached) are the seen for each diagnostic mop, with the possible
exception of Prob. 62 #5 (051 on the sheet dated 1/9/62) in which schizophrenics
show a marginal F—r-atio (reweion) which depressivee do not.

'Ihe

3. I looked at the covariance data of Prob. 62 91-5 to determine to
meat extent the pro-data contributed to the poet-difference. (i.e. , does pro-mm Y-oquare
data cmtrihut
ute to precision of difference scores”. Comparing”
to sun Moore of coeem, shows that the use of pro-data increases precision
markedly for each variable, for a factor of at least 2X and occaoimally as
ouch as ex.
14.
The comical correlation model for EEG and psychological tests
in the pro-position is batrig‘uing and I am enclosing a set of references which
show com similar relationships. The moot careful studies are
of
Heady—Castle. Warm, Ohriet, and the review by Ellingoon.

W

Over-riding the pattern in the Hillside data

is the factor of

age,

and any ftmther studies must “parcelaout' this factor. If adolescents are
included, they have higher memento of elm wave activity and lower performance
than adults. If aged are included (eee (wrist) than there is poorer performance
and higher slow wave activity. .If both are in the Sample (as with Hillside) then
this my be a factor in the result.
5. The omonical nodal is intriguing and as econ as Vanderplae
back from his vacatim, I will ask him to run a few trials at Washington

is

University.

If you wish to follow-up the psychological» EEG relatimehip,
amtl'nr analysis or the post date, or the D-oooree for the total grow
We! be dame. (Or. is it preferable to do each drug separately? I think not.)
5.

I

was moot

intrigued by your library approadr. I have diemzeoed

Mahler again and he responmo by again suggesting that
start with Peychophem. Ahotrecte and an SDI mdel. He had proposed this
last year, and P80 8 mm tmmed us dam for "momma" reasons. I
have called Jon and asked if we could not revive this proposal.

my

we

interest with

In the mammile, I am running a few ewerinente with deecrdptigo;
and carrying the
having references from various sources perched on
.

literatm

m;

retrieval“ promung.
In checking the IBM 7000mm: librery programs, we fomd name to
provideadictionary. 'Ihereieoneforwaotsmitteninmmnaeeomdinmchine.
. If your Form list and/or deck is available in Mateo form, I
would he mteful for a copy.
This letter is long enough. I will send it off, and will follow with
another copy of our new write-onto and :pephe for EEG analyaie. My best wishes
for a Happy New Year, and for many, my; more to cane.
on “information

»

Sincerely yours ,
Hex
Mrzaw

one.

Pink,

Director

M. D.

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