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                  <text>July 16, 1997
Harold S. Orchow, M.D.
Montevista Hospital
5900 West Rochelle Avenue
Las Vegas NV 89103
Dear Dr. Orchow,
The relationships between number and frequency of seizures, reduction in
mood disorder (efﬁcacy), increase in cognitive symptoms (safety), and electrode
placement are described in an extensive series of reports. The details are well described
by Abrams in his textbook Electroconvulsive Therapy (Oxford U. Press, 3rd Ed., 1997).
The most recent reports are those from Jerusalem by Bernard Lerer and his co-workers.
1.

2.
3.
4.
5.

Efﬁcacy in ECT for mood disorder improves with both frequency and
number of treatments.
Cognitive symptoms worsen as number and frequency of treatments
increase.
Efﬁcacy is greater for bilateral electrode placement, but such efﬁcacy
is associated with greater cognitive symptoms.
Efﬁcacy is less for unilateral electrode placement, and such lesser
efﬁcacy is accompanied by lesser cognitive symptoms.
Twice a week treatments achieve the same efﬁcacy and less cognitive
effects than three times a week treatments; but two weeks after the end
of the treatment series, when efﬁcacy is equivalent, cognitive effects
are not distinguishable.

As a consequence of these syllogisms, practitioners select the parameters
of treatment according to the severity of the symptoms. For severely ill and debitated

patients, where one seeks immediate improvement and is less concerned with cognitive
effects, ECT is given 3x/week with bilateral placement. This assures the best results. [In
severely manic or psychotic patients, this series may begin with two to four treatments
daily.]
For patients who are not too distressed, where cognitive effects are feared,
with unilateral electrode placements, at 3x per week.
treated
patients are

�In the elderly, where cognition is a principal risk, treatments are given
with bilateral placements no more frequently than two times a week.
Some practitioners deliver two seizures in a single setting. This is a relic

of 'multiple monitoered ECT' developed by Blachly and Gowing in 1966. MMECT was

tested and shown to increase risks with limited gains. The practice is no longer endorsed
except in the very severely manic, psychotic, or stuporous patient where an immediate
effect is required.
The practice of giving 12 treatments in four to ﬁve days, even with
unilateral electrode placement, sounds like MMECT — a practice which is not generally
recommended. The APA Task Force of 1990 wafﬂed on these data and recommendations
because the members of the panel were aware that many practitioners were still using the
MMECT model. A better review of MMECT is to be found in Abrams' textbook.
I trust these remarks are helpful.

For other opinions, you may want to post a speciﬁc case example on the
intemet site of 'convulsive-therapy@psycom.net' and see what others answer.
Sincerely yours,
Max Fink, M.D.

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