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                  <text>j-

W

March 14, 1992
Werner Herrmann, MD.

Clinical Psychophysiology

Freie Univesitat Berlin
Eschenalle 3
D-1000 Berlin 13
FRG
Dear Werner,

First, about the IPEG Program. Turan and I met yesterday and
completed the program, worked out the program printing, and made suggestions
regarding the social calendar for the meeting. It looks good.
With regard to the MacNeill et al report in Neuropsychobiology. I agree
that you accept what you deem useful. When reviewers differ as to their
recommendations, I do not think ’democracy’ is effective; the editor must make a
judgement based on the merits of the paper [as he sees it] using the advice of
reviewers for specific points.
You ask how I proceed as editor of Convulsive Therapy. I see the role
of the Editor as ’gatekeeper’and as a ’leader’. I try to determine whether an
original article asserts something new, whether it is likely to be true, and whether
it is likely to be ’true’ in a few years. Articles that meet these criteria and the
support of reviewers are accepted with enthusiasm. Other articles are accepted if
they usefully teach -- an experience that might be useful to others, or a technical
point that has merit. If the report is an opinion piece -- a commentary or
editorial -- I ask that it be related to something published recently, or that it
makes a new argument. Finally, reviews are very helpful if they are reasonably
complete (I check the citation lists myself) and if the conclusions may be helpful
to the reader, whether as a student or as a researcher.
The Editor is expected to stimulate and request articles that make new
points. I often leave a scientific meeting with notes that lead to letters and later
to editorials or reviews which I publish.
The section on pharmaco-EEG in Neuropsychobiology has not made a
concerted effort to improve our practice. As I recall the articles, they are mainly
archival reports of studies that follow standard models. Many are not definitive,
weakening our message. They have rarely been accompanied by critiques or
editorials.
‘

�Werner Herrmann, MD.

Page 2

The next IPEG meeting has two important issues that warrant
publication. The papers of the Classification Symposium may usefully be
published, perhaps as a special supplement, with a discussion of the relevance of
animal models for clinical psychopharmacology. Opinions are divided between the
pharmacologists who have a distinct faith that rat studies are the road to defining
new psychoactive entities [after all, it is their livelihood], and the clinicians who
recall that almost all that is useful in clinical psychiatry has come from clinical
efforts, and that so far, no new compound or idea has come from pharmacologic
studies.

The PK/PD symposium exemplifies a most useful application. It
deserves a separate publication, with a discussion of the BGA and FDA positions,
and arguments that pharmaco-EEG studies in man have something to offer
clinical medicine, something more than is offered by routine PK/PD testing when
applied to psychoactive (and neurologic active) drugs.
My principal argument with Kiinkel was that he appeared passive in
attitude, leaving the section archival and ’no fun’ to read. Miiller-Oerlinghausen
made a good point in the latest issue of Pharmacopsychiatry, when he accepted
your three papers and then asked me to write a commentary. The ’package’ should
have been part of the Pharmaco-EEG section of Neuropsychobiology. [Is it
premature for two journals to compete for the limited pharmaco-EEG material?]
As editor of the section in Neuropsychobiology, it will take much work;
a good beginning can be made at the IPEG meeting where you should try to

capture the best papers.

My best regards.
Sincerely yours,

Max Fink, M.D.
Professor of Psychiatry
,

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