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                  <text>April 19, 1991
Dr. J .A.G. Watt
Gartnaval Royal Hospital Psychiatric Services
1055 Great Western Road
Glasgow G12 OXH

United Kingdom
Dear Dr. Watt,

You suggest that two groups be studied, one of major depressed of the
mild type and another of dysthymia of 6 months to 2 years duration. Alas, you will
not be justified to use ECT in either population. For depressives of mild type, you
will surely exclude those with melancholia, psychosis, and suicidality precisely the
best candidates for ECT. As for dysthymics, such as are identifiable are those who
are chronically ill, for durations measured in years or decades, and who in the older
days, were identified as ’neurotic’ or ’reactive’ depressed. Surely, not candidates for
ECT.
-—

ECT remains a treatment for severely ill patients, those who are
hospitalized or who warrant hospitalization. Any study which suggests its use in
those with lesser degrees of illness will be difficult, in our society at least.
As for power calculations, these are quite easy. If delusional depressed
are selected, the success with ECT will bhe 60-80%, with any antidepressant alone,
less than 30%; a power calculation will find about 30 patients in each cell will do
nicely.

Good luck in your studies.
Sincerely yours,

Max Fink, MD.

Professor of Psychiatry

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              <text>Correspondence to: Watt, J. A. G.</text>
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              <text>1990 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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