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                  <text>iarch 29, 1989
John M. Ackerman, M.D.
2417 Castillo

Street

Santa Barbara, California 93105
.v—

-

"

i am acquainted with publications describing electro—acupuncture ECT
(EACT) by Dr. Xue and his coworkers in Beijing, and another by Drs. He and
Zhuosan (in a separate report from Xian). Both reports appeared in CONVULSIVE
THERAPY in 1985. They suggested an equivalence in efficacy between EACT and
conventional ECT but greater safety for EACT. in the absence of a random

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Dear Dr. Ackerman,

'

assignnient study with independent assessments of outcome and cognition, we
remain in the dark as to the importance of these reports.

‘

The second report, "An investigation of Transient Absence of Brain Wave
During Convulsion of EACT and ECT" seems to be an abstract. The citation is not
given. From the abstract, it is not clear when in the course of the seizure, the
TAB W occurred. In 1966, Blachly and Gowing described the end-point of EEGmonitored seizures as 'precise' or 'imprecise‘. Recent studies of the end point find
that more than 2/3 of seizures end in a period of iso-electric activity, a flat EEG
which may be what is described by Dr. Xue as TABW. The period of isoelectric
activity in ECT varies but may be prolonged for more than a few minutes in
unusual cases. Usually the duration is under 30 seconds. We are now investigating
whether a precise end-point is a favorable prognostic sign (and am imprecise endpoint, an unfavorable one). If i am considering the same phenomenon (TABW =
isoelectric activity), then Dr. Xue's observation that 4.1% of cases with EACT had
TABW while 31.496 of ECT cases had TABW, would suggest that ECT was the more
favorable (effective) treatment. But such speculation needs to be examined with
Dr. Xue or another practitioner of EACT.

At one time, Dr. Xue correSponded with me and I invited him to visit Stony
Brook where l was prepared to let him demonstrate his technique in our unit. He
was unable to accept, so i do not have any direct experience with EACT.

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A

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Like other modifications of ECT, the burden of proof of claims of efficacy

or safety lies with the protagonist. I do not know how many Cases would be required
to define a difference between EACT and ECT, or if there is a difference. i

suppose one could estimate the number of cases needed after observing EACT
practice in a few model cases. in assessing differences between unilateral and
bilateral electrode placements, for example, it required a few hundred cases to

demonstrate a difference.

�Dr. John Ackerman

EACT vs ECT

-

Page 2

If Dr. Johnson is enthusiastic to try EACT, an open clinical trial in
characteristic depressed (and delusional) cases would be of some interest. If he
could verify the claims that seizures were induced with remarkably low currents;
that needle electrodes were safe and effective; and that the number of treatments
needed were either equal or fewer than ECT, it might justify others trying EACT.
During Dr. Xue's visit, did he demonstrate EACT? if yes, I would be pleased
to talk to an American observer who may have participated in such a

demonstration.

'

"

Thank you for bringing Dr. Xue's arguments to my attention. if there is
more that needs discussion, you can call me most mornings at my office (5164M
2929).
Sincerely yours,

Max Fink, MAD.

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