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                  <text>»-

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December 1’4, 1987
Morris A. Lipton, M. D.
Deputy Editor, American Journal 93 Psychiatry
1400 K

Street, N. W.

Washington, D.C. 20005
Dear Morry,

It was a pleasure to talk with you in San Juan. On my return, I read the
letter by Lieber on the "Treatment of Rapid Cycling Bipolar Patients"in the latest
issue of the 5.13. The letter recommends complex polypharmacy as a treatment of
therapy resistant depression. But the letter gives no data as to patient characteristics, history, in-patient or out-patient status, assessment of efficacy of
treatments, trials with established treatments, Egg. The letter seems to be a
throwback to the old—fashioned testimonial which modern psychopharmacology
eschews.

letter is published in the Journal, it suggests that the practice has
review
standards of the Journal and the Association. Do spontaneous
met peer
in response to an article'in the Journal, meet the peersubmitted
letters, not
review standards of Journal articles? Was this letter reviewed by any of the
acknowledged psychopharmacologistsof the Board of Editors? If yes, is there a
message in the letter that our attitude to polypharmacy should change?
As the

if no, would you consider soliciting letters to argue against the adoption of
the Lieber recommendations until they have met established standards of study for
efficacy and safety?

a fact of practice, as we often read in the
which
records
come our way, polypharmacy is not generally condoned
malpractice
by our experience or by our science. is the publication of this letter not a
regrettable mis-step?
While polypharmacy is

My best regards.

Sincerely yours,
Max Fink, MD.
Professor of Psychiatry

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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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