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                  <text>n"..-

wwwmmgv

“W

Wrwv-Vt

~r.-

umm‘qu-Wl-wv

wuv-wvw

3*

WW
\W

October 1, 1979

Prof. Dr.

H. Helmchen

Nussbaumallee

1000 Berlin

36

19

Dear Helmchen,

for the reprints of your studies of the behavioral
changes in epilepsy. I found the work quite good and complementary to
our own interest in the effects of seizures in ECT. Over the years,
I have often wondered why more epileptologists did not take advantage of
the natural experiments which psychiatrists provide in the BCT process, in
aleowing a study of the interrelations between degree of brain change,
number and frequency of seizures, and psychopathology. When I did my
principal studies of psychopathology, in the late 1950’s, not as much was
known about the assessment of behavior and our work was quite coarse.Were
we to do the same studies today, our methods would be more detailed and
would parallel your efforts more closely.
Thank you

I also enclose a reprint of our recent study of the EEG
effects of phenytoin. It shows clearly that there is an intimate relation
between plasma level of phenytoin and BEG response. I think the failure
of many physicians to get behavioral effects in patients with neurosis may
be due to the low levels they used.
Again,

my

thanks for your help.

My

best regards.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

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