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                  <text>3M”

April 23, 1979
Albert J. Stunkard, M.D.
Professor of Psychiatry
Hospital of the University
of Pennsylvania
205 Pieraol Bldg./Gl

‘

Philadelphia, Pa. lQth
Dear Mikey,
much

I will miss you
less erudite.

on

the

V. A.

committee, and the sessions

will be

I found reading your report on fenfluramine interesting and
The data tables are more imgresaive than the figures, which
suggest that the placebo treated subjects lost almost as much weight

useful.

.

;

f

as those who were medicated. The graphs indicate a median loan of
9.5 kg for the medicated aubJecta and 7.5 kg for placebo. What was
the secret ingredient in both groups? WOuld the report be strength—
ened by adding some weight lose data? Have you considered OPT for

these data?

report of our study on fenfluramine is enclosed. we were
less interested in the clinical effects than in the EEG profile.
In another study in 1968, we carried out an open trial of fenfluramine in obese subjects, found sedation and dry mouth with weight
and appetite loss. We did not publish these data, which were
useful principally in examining whether sedation or stimulation
occurred in our subjects, as a follow-up of our EEG assessment.
A

My

regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

MF:bc

Encl.

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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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