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                  <text>5..

m...

January 7, 1989

.
m

m—p

um"?

_m

"a...

r

W'mﬂ'l‘

v-m-arrsrm

s-

«WWW

WY’

‘g’MWa'avﬁ'v—"W‘M

Frank Ayd. M.D.
Medical Communications

Ayd

Baltimore, Maryland
Dear Frank,

Enclosed is a copy of the report which we recently
published describing our experiences with phenytoin. From these data,
I think we can understand that the varied reports of the efficacy of
this compound in the treatment of the mentally 111 may have resulted from
inadequate dosage“ poor compliance with resulting plasma levels that were
possibly inadequate for the induction of changes in brain function. If
these findings are to be trusted (and I think they should be), then we
are justified in undertaking additional studies of phenytoin in cases
of neurotic depression and anxiety, monitoring the plasma levels so that
persistent levels of at least Sag/ml are maintained.
My

best wishes for

a healthy and

successful

1980.

Sincerely yours,
Max Pink, M.D.
Professor of Psychiatry

�</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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