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                  <text>Danuary

l,

1978

Melvin Muroff, Ph.D.

l2 Harcourt

Scarsdale ,

Road

NY

Ref: Hayden Harman, age

Dear Mel,

8

Wwv-m-wrwv-mr

wwm

“war-war—

m

w

vw-.mwm;.u..

Wu

sum—7:»:

I

have read the

(dated 12/6/77) of the patient,

file

and reviewed the
Hayden Harman.

EEG

record

The EEG record is well done and includes alert, photic
and
stimulation
hyperventilation sections. These show mell modulated
dominant
alpha
activity of relatively low voltage. Slow frequencies
are not prominent, nor are they stimulated by hyperventilation in undue
amounts. I concur in hhe report by Dr. Scheinberg that this record does
not show any abnormality inconsistent with the patient's age. We should
note, however, that an important part of the EEG capability was not
used, that of sleep recording. Numerous authors, notably Gibbs and
his students, have repeatedly emphasized thp significance of such
recording particularly in young patients in whom one is seeking

evidence of dysrhythmia.

rest of the file is replete with evidence of cerebral
dysfunction, particularly the report of the observations by Dr. Ballweg.
These data, combined with the behavior and the reports in the psychological
tests (see particularly the figure drawn by the child) are evidence of
dysfunction. Unfortunatley, it is not possible to determine from these
data whether the dysfunction is episodic.
The most conservative approach to problems of this
dimension is the conbined pharmacologic~psychologic. The former provides
The

an opportunity to alter
one may be fortunate in

cerebral functions, and with proper manipulation,
affecting the functions favorably. Two courses
are available: a trial of an anticonvulsant, such as diphenylhydantoin
(Dialantin) in doses up to 300 mg/day; or a psychostimulant, either
methylphenidate (Ritalin) or dextroamphetamine (Dexedrine). I favor the
use of methylphenydate as it has a better safety margin. The use of these
drugs should be combined with sessions with the child and on occasion, with
the parents, to assist in the adjustments necessary in helping a child whose

�mm

[Jp—
n...

‘vw

“r

Dr. Melvin Muroff

........

January 1, 1978

.............

page 2

..mww.aw-nw.w&lt;~wu,

achievements may not be as good as his or his family's aspirations.

If there is

a choice in the sequence of drugs to be

tried,

would depend on the clinical findings as your best guide. Since you
already have noted the similarity of this boy's problems to those
seen in others helped by diphenylhydantoin, I would encourage its

I

trial first.

If there is a special need to verify the possibility
of dysrhythmia further, then a sleep EEG could be obtained. If the
laboratory at Lawrence Hospital is reluctant to carry this out, I
would suggest you enquire whether Dr. Fred Struve of the Hillside
Hospital is willing to do the test for you. He is a Gibbs' student
and one of the best analysts of clinical sleep EEG records in the
region. The other is Dr. Eli Goldenson at the New York Neurological
Institute.

I trust these

are helpful.
for the success of this child'd treatment.
comments

My

best wishes

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

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