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                  <text>.,

ans-N. .w—n-e wwx—nw—ur

w

. —. "may

wwm

7m..‘wv

-

au—wv—w

September 29, 1977
rammwr—v'w'

‘m

Richard Resnick, M.D.
York Medical College

New
5

East 102 Street
York City

New

Dear Richard,
While

in Holland a

few weeks ago, following up on my

interest in the peptides that may affect brain functioﬁ, I was
presented with the enclosed reprint and asked whether I thought the
data warranted further study.

After reading the report, which shows that the administration
of a peptide derived from vasopressin will reduce the self administration
schedule of rats bar pressing for opiates, I bacame very interested.
It seems that this peptide has the same effect on self—administration
of opioids as the administration of an opioid; yet the compound has
no analgesic, respiratory, or sedating effects.

It

would be of

My

regards.

interest to determine if the compound
relieves drug seeking behavior in opiate dependent humans.
I presented the problem to Al Freedman and he seemed interested,
suggesting that I send you the reprint and arrange that we meet soon. I
am scheduled to teach at the College October 5 (8 to 10 p.m.) and
again October 26. If either evening is suitable for you, call me and
I can come in about 3:30 or 6 p.m. for a chat.
Sincerely yours,
Max

Fink,

M.D.

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