http://exhibits.library.stonybrook.edu/mfp/files/original/e6929ad218b229ed891a13edbe9cef33.pdf 7d1443d773ea85a39d6c36ea25dc90f8 PDF Text Text WW. .7“ . y, x v—r-u. .«rw ~»r-wu.-_——nww- ‘lu—P'r—KyH—IWrwm‘fl—HnVn mm. “Mm. vam- m. 7“ mymw-wm.mmuwm w..."- mw...-n-—. 1... .«w—n. wan-mun.“ . - ‘ww‘F/W p":- w- n WWI-P. «nun-1w. -.v..——v-—.~ x 4»/ November 21, 1977 Nathan 8. Kline, M.D. Rockiend Research Institute Orangeburg, New York 10962 Deer Nate, read the file on Dr. Vacant G. Joehi with some interest. As observations, it is that INH plus Vitamin B6 served to case of catatonia. The patient had two EEG records done, receiving INH. There was a remarkable change in the EEG, characterized by the appearance of generalized, dominant slow theta activity which became more intense with hyperventilation. Dr. Joshi notes that he has used.the combination in other schizophrenic patients with success. I am not surprised by his report. It is consistent with two sets of data. The response of catatonic patients is notoriously rapid when any change is induced in the CNS. Thus, barbiturates, amphetamines. and BCT have each been successfully used in catatonia. The most interesting is the latter, A recent report by Breakey and Kala (British Medical Jounnal 2: 357~359, 1377) finds that ECT-wcs remarkably successful in relieving more than a dozen cases of catatonia after typhoid fever. The predominant finding in ECT in the EEG is the development of high voltage slow waves in the theta range which are responsive to hyperventI have I understand his relieve a single before and while .- . ilation. The other observation is that of the association of EEG and behavior after psychoactive drugs. It is clear that any compound that alters brain function witl show its effects in the EEG, and when such effects are observed by clinicians, the EEG patterns will be clear and will follow predictable patterns. Dr. Joshi's paper suggests that the high doses of INH which he is using do have an effect on the EEG similar to BC? or antidepressant drugs. It is not possible for us to corroborate Dr. Joshi's findings. We could cooperate with other clinicians whb wish to duplicate his observations by carrying out the EEG analyses on records collected in another site, if the records are collected on tape compatible with our recorders. We also lack the funds for a research fellowship at this time, although is possible that you and the other Research Directors may be making funds for fellowships available. it and I for the opportunity to read this interesting communications congratulate Dr. Joshi on his fine observations. Thank you Sincerely yours, Max Pink, M.D. Professor of Psychiatry w—n—u— � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Kline, Nathan S. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-028-6-259 Date A point or period of time associated with an event in the lifecycle of the resource 1977 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence