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                  <text>rv"n'rrmw—uv&lt;

..—

—.v—w‘;w&gt;-&lt;

.m‘w‘w «tm'wb-

1

,

M

...-.»..-wum-.w-

~ .7

Harm.

—..

,

5"".‘1m.

w"

”my

~"a-F‘

- mm...“:r»—q——-"/~-m~vv—\T~~wv|Wuwm'w- r»,

.-

.....__ 71-12

June 30, 1976
Dear Don,
We

have done one pharmacodynamic study of bromazepam. The

report is enclosed.

these data, bromazepam is hardly distinguishable from
to the amount found in the blood when the EEG effects
are the same as those of diazepam, i.e., we thought bromazepam a more
active agent in the brain (high EEG levels) with lower bbood levels.
Schwartz and Conney of Hoffmann—La Roche suggested that the sensitivity
of the methods was such that there may be an error in the bromazepam
blood levels, and that this finding was possibly an artefact.
From

diazepam except as

The manufacturer is Hoffmann—La Roche;
Bookman (212 695 1400, x3772).

Dr.

Philip

any

clinical experience with the

the contact is

I cannot answer the clinical question as

My

compound.

regards.
Sincerely yours,
Max

Fink,

M.D.

we

have not had

(“Wm-w.

4

‘»

puwwmm—

�</text>
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              <text>Correspondence to: Klein, Donald F.</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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