http://exhibits.library.stonybrook.edu/mfp/files/original/078834462cc3a20ec0255e7f9fe0e68b.pdf dd5aeddd94d1049648c737721c4e3573 PDF Text Text r... _, ~- .. v .m— , _,. ,_ 7 m.“ . , , -—»-.n—— v—wn v .. V. .. u; . «a w. A , wm' ...wm..—wq~u~.—.u-«”emu—VHF. a...” "mm»".vmvwn «‘L ........-._. . WWW . . m -"I:r='mvu-vrllvs4r1‘17 mt December 29, 1976 Ing. M. Matejcek Sandoz Ltd. #002 Basel, Switzerland » Dear Matejcek, I was pleased to receive the enclosed inquiry and as I answered the many questions, I became more enthusiastic; hence this letter. Many years ago, in 1968 and again in 1969, I organized meetings in my laboratory in New York. I remember a session at which Creuzfeldt came and argued very logically for more basic studies. At the time, I ignored his comments, but lately that need had become all the more apparent. I know that some workers are occupied with the technical issues of electrodes, EEG reduction methods, etc. But these issues have been solved, to some extent, and what seems to be needed, are studies relating the EEG changes to behavior. The diagnostic use of EEG profiles to define new drugs has been successful; some applications to pharmacodynamics have been interesting; but we lack the understanding of the significance of fast waves for behavior for example. Past waves increase after barbiturates (sedatives) and thymoleptics. Are the chemical changes in the brain the same or do these same rhythms reflect different chemistries? Or, as is also likely, we have not yet resolved the differences in the fast waves after barbiturates and thymoleptics ? Further, of what predictive value for neurohumors are the EEG changes. We know that anticholinergic drugs elicit the same BEG effects as the thymoleptics. Does that mean that thymoleptics act via a reduction of acetylcholine in the brain ? And so on. have struggled for years to have pharmaco—BEG recognized At the ACNP, for example, each of the early years was marked by an BEG symposium, but these became redundant and the memebers disinterested when we failed to show the scientific merit of the work. At times, the data has been presented at psychiatric and at BEG meetings, but these disciplines are interested mainly in the practical uses, and ever since psychiatrists decided to ignore the sedation threshold work of Shagass, Goldman and they have We at major meetings. Itil, . -.. v. _ yum-“1......—pg,» .- �..........December 29, Mr. Maeejcik 1976 ..... ...... page 2 ignored the new developments in EEG and drugs. I think that meetings should be held independent of the main societies, and related th them mainly for the convenience of timing and the reduction in expense. Surely, meetings should be organized alternately in the U.S. and Europe, perhaps in Asia when the opportunity presents. If a meeting can be held in a working laboratory, then it should be held there-- giving the participants a chance to see the facilities and ask questions regarding tech— nical issues. Society should be organized formally, with rules and The by—laws to privide he graduated. some continuity and some dues which could The restoof the answers are on the form. Perhaps the meeting could be held in Amsterdam at the International EEG In September 1977 ? With a visit to Paris at the time of the course in EEG to Btevenon, or to Basle ? ? ? first My best wishes Ma healthy and a successful 1977 .,._.,-r Sincerely yours, Pink, M.D. Professor of Psychiatry Max I � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Matejcek, Ingrid M. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-028-4-164 Date A point or period of time associated with an event in the lifecycle of the resource 1976 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. 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