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May

Robert L.

Spitser,

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197*:

M. D.

Director, Evaluation Section
Biometrics Research
State of Rev York

Department of Mental Hygiene
722 West 168th Street
New

York, New York 10032

Dear Bob and Jean:

Criteria
I have read the sﬂhmission of ”Research Diagnostic
A

'

formidable produc—
for e Selected Group of Functional Conditions".
tion! Congratulations!
While the details are necessary, I find the descriptions
complex and "phenotypic". By that I mean that the clues which have
come from genetics, and the lesser clues from neurophysiology, and
the response to treatment. are not included in the classification.
Considering the state of the art, this may be necessary, but I
would be more enthusiastic in applying this classification if there
were ways to include the suggestions in the evaluation.

principal omission is the response to prior treatment
and the response to a therapeutic trial in the present classifica—
or hypo—
tion. The response to lithium by those with manic illness
from
the
nsnic episodes may he used to separate these two groups
schizophrenics. Some scientists claim that the response to ami~
triptyline is of diagnostic value in bipolar depression. In the
The

that Don Klein and I did more than fifteen years ago,whoververe
reconvinced that there were sub-groups of the mentally
sponded differently to phenothiasines and impramine. These comments
should be enough to suggest that the response to therapy may have

work

some

ill

place in the classification scheme.

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With regard to your specific question, I never use
"ihnic Illness" and "Hypomsnic Episodes", for I was taught that
"mania" is "mania". I also find the syndrome "Schizo-affective

type", difficult to differentiate from manic ill~
ness. I
if the difference between "minor dysphoric illness"
_end "dysphoric personality" is not 3 case of nitpicking.
disorder.

manic
wonder

With regard

to Items

1h and 15, I think alcoholism
e sub—type of drug dependence.

is not

I find
s separate disorder, but is
"drug
"drug
dependence. opiate type",
useful the classification
dependence, alcoholic type", and "drug dependence, mixed type".
has suggested that "homosexuality" not a diagnosis of mental disorder, I would accept this View.
As

the

APA

These comments are not to be interpreted as criticisms,
fbr I think you and your teammates have done a splendid Job. I
would be pleased to see the versbon after the next review.

Sincerely yours,
Fink, M. D.
Professor of Psychiatry

Max

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