http://exhibits.library.stonybrook.edu/mfp/files/original/47dee63ba9e6c38c32cbe1706342fc28.pdf 18acc3486e05b56f405f2e0c16761032 PDF Text Text it, February Rdbert Robinson, M.D. A. H. Robins Co. 1&0? Cummings Drive Richmond, 1971; Virginia 23220 Dear Dr. Robinson, the initial dose-finding studies of ARR-2277 and are satisfied that single 10 mg doses are safe and elicit systematic, dose-related EEG changes. We have completed have also completed the assays of the canparison substance, haloperidol, and are satisfied that single 6 mg doses elicit systematic effects. We believe that this dose may be above threshold, hooever, and we are exploring an additional group of We subjects at It mg. enclosing a copy of our work-sheets rOr your information. I have asked my staff to summarize the data of these initial studies and a report will be sent to you as soon as it I am is completed. ‘ Should the h mg haloperidol doses be below threshold, we will undertake the comparison, classification study of placebo, AER-2277. and haloperidol using 10 mg and 6 mg doses respectively. that dose will be It the h mg dose of haloperidol is satbsfactory, used. In either case, the systematic study will begin before the end of February, and should be completed in 2 months. Thank you for your patience, and my best regards. Sincerely yours, .v ,A .uy WNN'W'IV‘wh-rrw-u - Fink, th Professor M.D. of Psychiatry � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Yolles, Stanley F. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-027-5-366 Date A point or period of time associated with an event in the lifecycle of the resource 1974 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence