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                  <text>TBSB:09SSC

April 18, 1973
Turan Itil, M.D.
shoo Arsenal Street
St. Louis, Missouri
Dear Turen,

as

Enclosed

we

discussed.

is a revised protocol of the

The only item

ORF

8063 study

omitted is the collection of blood samples.

They (at Ortho) are willing to analyse samples for car 8063
and for the metabolite. In our preliminary studies, the metabolite
has e very long persistence, and it is possible that it is this
agent that in the active agent. It would be most useful if the
staff could collect and freeze 10 cc blood samples at each
visit. Near the end of the study we could attempt to ship these

under dry ice and if the analyses are done, it will provide
an independent measure of whether the drug wee taken, and
a reference for the therapeutic effects.

records.

It

could also be useful in conjunction with the

I would, therefore, ask

your knowledge of the
My

setting

EEG

you to review the protocol with
and add the necessary instructions.

best regards.
Sincerely yours,
,2?

Max

Fink,

24.9.

�</text>
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              <text>Correspondence to: United of Omaha</text>
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              <text>1973 </text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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