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                  <text>H

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7383—01333

January 6, 1973
Janice Stevens,

M.D.

Massachusetts General Hospital
Boston, Massachusetts OEllh
Dear Jan,

It is good to have the opportunity to review an ECT
and one that seems well founded and well designed.
again,
project
months ago, I received the engineers report fer review-by Weaver, Rvaris, Rush and Peananen which described the
parameters of the seizure stimulus in exquisite detail. At that time

the report

Some

I found the report fascinating reading-- a bit too long for the

Journal, and recommended approval with a suggestion that the number of

tables be reduced.

Apparently, these authors have interested a young psychiatrist
in the problem, and the design of the experiment, the selection of
cases, the intent, and the methods are all good. The project needs
doing, for as the recent report and editorial intthe Archives indicated,
the machines we now use are faulty. and the parameters of the stimulus
are poorly defined. Indeed, in the engineers report, they refer to
the best papers in the field, including that done by my associate
(Green, 1960) and Maxwell (1968).

If there are flaws in the application, they are trifling.
for example, is the emphasis on producing a stimulus which
is minimal in intensity (see page 17, last paragraph, "It would seem
almost a prime fhcie case that the use of the least effective energy
dbse would result in less short—range and long-range morbidity."),
when what they really wish to define are the relation between the parameters
of the current and the therapeutic effect (measured as changes in
behavioral scores) and the morbidity (measured as changes in the
Reitan battery). The latter emphasis is more mature and more in keeping
with an academic need and tradition, but the other View is not one
that is easily criticized.
One,

I would also question the sequence of problems they wish to
attack»~ but that too is a matter of style and not a criticism.
application asks for little
principal question of cost is the item of administration of
the Halstead tasks. This is a complex test, and if done by rote, by
a psychologist paid by the session, the results may very velllbe of

extra.

The

They are well equipped, and the

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limited value. Taking measurements in depressed patients before
treatment is difficult; and taking them after treatment may be
confusing. I would hazard a guess that this expenditure will be
wasted. The solution is to recommend the appointment of a psychologist
(even at an increased cost) who could attend to the measurement
of memory test changes. From our work, the memory tests (only some
of which are in the Reitan battery) are the best indices of the
differences betveen unilateral and bilateral seizures, and
between single and multiple seizures. If they follow the usual
'consultation'method, these data will probably be useless.

If

to save money, you could ask whyﬂush is
should have already been given (and
advice
being paid-~ his
Paanenen is not, yet he will build the instruments ).
proposal;

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one wanted

of detail and tactics. I like the
field; there is little similar work

But these are matters

it

is

needed in the

going on that I know of; and these non do haves prior experience in
animals upon which they are building. In the site visit, I would
be most interested in whether the P.I.. Dr. Nies, seems capable of
bringing the talents of a psychiatric nature that are sorely needed
in the evaluation to the setting; and also would ask about the

test battery.

mxxr-rr-mvmwm-v—v-wr

thanks for letting me read this prOposal.It is
interesting rollerbup to the report I read earlier by the
engineers in this team !
My

..

My

an

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

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