http://exhibits.library.stonybrook.edu/mfp/files/original/d21aa74b052bb88bf3b0b2981afe0a7f.pdf f8a5010c560d42f965c5869fcdfddbfc PDF Text Text 5373—50? January 30th. 1973 Dr. E. 3. Terry. Mediaal Director, Pharma Research (Canada) 250 Hymns Blvi., Pointa»01nire, mtrcel 730’ Ltd.. POQO Dear Sketch, I am emulating a aopy of our summary of the preljminary data on Pflnfh360L. In the early trials, under 200 mg, we failed to aliait systematic effects. Subjects beggn to raport symptama at 250 mg andehen we proeeedea to 350 and hue mg, the symptoms of tachycardia, hunger and nausea. tenaenans and waaknenn par-13%ad for many hours. At doses of 300~350 mg thnsa uymptame arcse 60~90 m1nu$es after ingestion. parsistcd for up to 6-8 haurs, and were tolersble. In raviawing the EEG changas at these-doses, a decreasa in amplitufie, an increase in alpha activity and a decrease in slower freqnnnciea are the moat treqnent changes. These are small in magnitude. hawwver. At this Juncture, the profile is most like that or a dextroamghetamine—like stimulant, and not a sedative. Vb havu begun a systematic camyariaon of PRnF-BGCL with fentlnramine (ho mg) and dcxtroamphetamine (10 mg). Thrae subjects are alrnady in the aerian, the additional nine should begin within the next few weeks. I anticipate the study to camplete the data collection phase in midmApril. I will be grateful far the additional auppliea. Sincerely yours, ‘ "‘1' " ‘ " “ ' ' Mix Fink. M.D. Proflsaar or Paychiatry mac-vznuwwsr/wrvzx'-“-‘> MF/id � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Terry, E.N. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-026-7-546 Date A point or period of time associated with an event in the lifecycle of the resource 1973 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence