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                  <text>autumn-18-

o'f"

3...“.a

01“

‘
.--

K

§731-511I
a"

February

lat.

1973

ﬁdbert Patarscn, Fh.D.,
Division on Rareotia Addietian and Drug Abuse,
Rational Institute of Mental Health,
5600 Fisheru Lane,
Roakville, Maryland 20852.
Dear Doctor

Fetcrsan.

Enclosed is an interim report on the contract "$tudy of
Chronic Hashish Uaara 1n.Greace" (EEM h8~70~98), reflecting
obaervntions fbr the period Jnky 1, 1972 to Dacnwbar 31, 1972.
The report presents two aeta at data: a comparison of the index
ease. of hashiah users with a “contra." groupggand the abaarvntions
in the aubjectn smoking marijuana, haahiah and TKCwbw9 1n doaea
equ1Valent ta ?8 to 150 mg TRG~An9.

in our study of the hashiah users, «a found few deficits in
phyliology or test behavior whieh aould be prennmea to result
from tha use of hushiah (* tdbaceo). The comparison group. which
magma wall selected, shows the same degree of hast @ysfunctinn
on most

tests.

The

principal diffsrenaea batween groups are in

tests_of mnmory, a greater use a! tobaaco, and enlarged
palpable liver sages. These findings are an few as to lead to
the conclusion that users do not differ from controls. With
scan

regard to the

.

dbnarmalities, raported in 1969 which sparked
these stunias, the changes wars nat present in this aamyle of
users, nor eantrols.
In thn acute arms studios, twn 6bs¢rvationa stand out:
the subjects respond to vary high doses of different fbrmn of
canndbia; and that thare may be differences in their rasponae
unrelated ﬁo THCnA~9 content along. From the first dbaarvationa
V! are tmpresaad that talersnce to the neutral effects of
canndbin in wall established; an&amp; from the amenda that aomgonenta
of marijuana and hashish cther than TEC~A~9 are behaviarally
active, and that these activities ean.be parcellea out.
EEG

ﬁnal of the data, particularly the detached statistical
antxysea of the EEG, and EEGébehavioral correlaticns of the acute
expcrimnntn are in precasa. and should be comylete by march. To
that extent. the enclosad summaries are preliminary.

�derunry lat,

~e-

Rdbnrt Pateracn, Ph.D.

1973

Thu next quarter in dadicnted to these analyses; and to
the drug withdrxwal trislu. The laﬁter exparimants assume greater
significanno with the syntematio dbnervatian of tolerance ta
chronie hashish use.

In our 1972-73 request to undertake these stuaies. vo
proaoctaa a tins schedule or 18 months. Support for the studies
tar cue year was given with our mutual understanding that we fill
quatterly rayorts, and based.on the pmogreas reported in January,
the continued support woulﬂ be reviewed in February and Professor
Stefania and the Association unuld be aﬁvised by the and or
derunrx, whether the contract woul&amp; be extenaea beyona June 23,
1973 or terminated.
with

Our grograaa in
uhnm we have met

this study

has bean monitcred by Dr. ﬁgure,

Copenhagen in August, ﬂew York in
December, and Whahington in January. His

in

Hovember, ﬂan Juan in
reperta shauld sugplement thase notes“ In adﬂition, WE have
submitteé samples of hashish to Dr. Branda; ana in our next vitit
t0 Athena (early February) um 91am to bring additional aamples rbr
assay in 31MB contract laboratories.
We

trust these notea-are helpful.
Sincerely yours,

Mm»:

Fink ,

M. D .

ExecutiVE Dirmctor

cc.

Wk.

Bunney,

;.D..

ﬁIMH

a. Saara, M.D., HIMH
Eleanor Carroll, NINE

C. stefanis, M.D., Axhana
A: ”a
MODI’

MF/ij
Ema.

mm;

m

'

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              <text>Correspondence to: Petersen, Robert</text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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