http://exhibits.library.stonybrook.edu/mfp/files/original/3373f2d6f5e1f4dfee4605736750dc8b.pdf 15ec2d695e878e5f4a80ec333d7428bc PDF Text Text flovonbor 22, 1972 Alan Ramsey, M.D. Modicnl Consultant National Inititute of Mental Health 5600 Fishers Lena Rockville, Haryland 20852 Boar Dr. Ramsey: Undnr the torn: of contract studies are in progress. 88M 42-72—207, the following _ (l) flelogeridgl. Twonty~four opiate dependent non have been withdrawn from heroin using decreasing doses of methadone and placed on either halopcridol 10 mg or placebo. Both groups have been given 4 mg of benzotropine with each dose of active drug or placebo. he methods of evaluation set forth in the contract are being uncd. The remaining subjects have received medication for two months or longer. An evaluation will be available in February March, 1973. study (2) Naloxono panoate. was completed The dooc~duration of antagonism in early September. We defined a maximum tion of 60 houra for 6 cc parenteral. A copy of the: report sent to you, and submitted to Cliu. Phanm. Thckap. (3) Czclgggging. Tho high dose study dura- was is continuing the definition of eccoptability, tolerance, and duration of antagonism to heroin. Ho ounnerircd the data of 20 mg oral, noting blockade to 25 mg heroin for 72 hours. A copy of that report is oncloocd. 1639 (naltrcxone). ‘wn provided a protocol for the and filed on IND application for the FDA on compound this study October 25. this was rcgintcrtd as received on Hovcnbcr 10. 1972. Of (4) EH Additional details of our aporetion were providod in your extensive site~vioit of October 26. - �Alan Ramsay, Hovonbcr 22, 1972 3.3. You may also be internscod in parallcl studios now rlsu in tho Division: in prog- a. _Digrcnogghino. H. at. enopnrating with the Citybeof canHaw Yeti in datining annual toxicology studion. which should platad by the and of tho your. b. Lovonnthggzl, We conplctod a second study of lava— uethadyl and confirmed our earlier rnport that‘ao :3 won effective for 72 hours, allowing a t.i.w. dosage schedule. Sincoraly yours, Fink, 3.9. Professor of Psychiatry Max MF:1g fine. � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Ramsey, Alan Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-026-5-359 Date A point or period of time associated with an event in the lifecycle of the resource 1972 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence