http://exhibits.library.stonybrook.edu/mfp/files/original/2b73eca24dae8b25c002681cdad5b9cc.pdf 738ab07f3de3ce171e838f6edafe8d9c PDF Text Text « aw. > ~ —"«v,.-V September 6, 1972 0 _~—~~~~~a—*— M E R A R D U M TO: A. M. Freedman, M.D. FROM: Max SUBJECT: Effects of Chronic Fink, M M.D. Methadone Intake on Performance The impact of chronic drug use on performance and throwing question. is a recurrent For most drug evaluations, various issues have come to the fore which raise doubts as to the generalizability of the task performance for the following reasons: (1) Sample: usually well motivated, specially selected subjects participate. (2) Task: life, usually artificial in relation to real often too simple. Setting: examination is in air conditioned, sterile environment; boredom and fatigue as factors are excluded; distractions (3) and competing stimuli are excluded. �A. H. Freedman, Md). (4) September 6, 1972 drug dosage Dosage: contrast to real life, is haphazard where intake overdose and withdrawal are Isbell (1948). The irregular, and studies of driving performance criticized for these reasons; (Kielhalz) have undertaken ”field” Gordon’s and real factors. For example, some recent with cannabis have been is well controlled, in and the Swiss tests. studies contrast with the earlier reports of conclusions (that methadone improves performance) are unconvincing since the issues (l~4) above apply. As an aside, Gordon has presented EEG data which contrasts with our findings: he claims methadone normalizes the KIéIDJ methddoneslows near frequencx’produces bursts, egg. gogglggiggz EEG; we find data is insufficient to support (l) The Cordon (2) Performance any contention . Should be encouraged and accident tests, under field conditions, rates, absenteeism, and X accept- able products used as indices to evaluate the questions raised by the Commission. � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Freedman A. M. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-026-4-333 Date A point or period of time associated with an event in the lifecycle of the resource 1972 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence