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                  <text>October 5th, 1972

Jafte,

Dr. Jerome
SADDAP,

The White

Eonse,‘

washington, D.C.
Dear

Jerry,
I

am

enclosing two preprints of reports that
American Psychiatric Association.

submitted to the

The levcmethadyl

we

have

study confirms our previous study

that ofyour co-workers that the effective 72 hour dose
of levomethadyl is store 70 mg. we are impressed with
both the safety and efficacy of levomehhadyl and would like
to undertake a more extensive clinical trial. In calling
N.I.M.H. regarding additional supplies, I have been notified
that the supplies are restricted, and plans for an extended
clinical study are not an adequate Justification for the
release of the available supplies. I have also been told
that the restrictions in studies are based on presumed
FDA requirements for extended toxicology.
Are we, in fact,
from
restricted
extending a levomethadyl study to all the
patients at Metropolitan Hospital?
and

'

The second report demonstrates that cyclesocine can
be given in higher dosages with good tolerance develoyment

for agonistic effects.

this be confirmed,

delivery schedule.

we

initial heroin
ha

challenges suggest
hours,and should
will undertake a three times a week
Our

an entension of antagonism

to

more than

(These two studies were done at the
College and will continue at that unit).
Good

New

York Medical

luck in your efforts!
Sincerely yours,

Max

MF/ij
Enos.

Fink,

M.D.

�</text>
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              <text>Correspondence to: Jaffe, Jerome H.</text>
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              <text>1972 </text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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