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                  <text>x
&lt;-.~,

7'

-.
w

,—._-

w.

an”,

August 10, 1972
yww‘wwavmwﬂ-JW-n

Allan Ramsay, M.D.
National Institute of Mental Health
Rockville, Maryland 20852

ewaquup4m‘n

Dear Allan,
-vu-.r.wa-

N,

nag-'3'

..a:a,,.g.—~

Separately, we have filed an IND for cyclazocine for the
on-going studies at the Metropolitan Mental Health Center, and I ahve
requested Dr. Levine to institute the proper procedures with Mr. Boyer
to sustain our supplies. He will tell you that we are treating about
80 patients daily, and while the majority are receiving 4~5 mg/day, there
are at least 12 who receive 8—11 mg/day, and we are proceeding in a
few to 20 mg/day.

Paralleltstudies of Z~cyclazocine are in progress. For
the present, we have adequate supplies, but these should he exhauseudd
within three months.

file

for chyclazocine, or will MIME
provide us with the supplies to continue the ongoing studies under our
Should we

new

contract

of the

FDA

a new IND

?‘

If we should file an IND, will you request the cooperation
regarding the extent of the submission ?
Will additional supplies be available through Mr. Boyer or

from Sterling-Winthrop

?

Meanwhile, we have hegun the study of haloperidol; the
animal pharmacology of diprenorphine is delayed by supplies from
England, which have been promised for later this month; and the study
of BC-2605 has been delayed by an administrative problem, which we feel

will

be resolved by the end of the month.

Thanks, again, for your help.

Sincerely yours,

:_.

ZV'N-aq

Fink, M.D.
Professor of Psychiatry

Max

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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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