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                  <text>wry-m.

a—u—r

~rvr

m

1
a

wwwarnmuw-ru.

'1.
aw.-

January 17, 1972
Maxwell Gordon, Ph.D.

Bristol Laboratories
Syracuse,

York

New

Dear ﬂax,

pleased to have the opportunity to review the
clinical pharmacology data on Clomacran— SKF 14336, for I had heard 05
the compound but had not read these dlta. It is a well studied compound,
and there is sufficient conventional evidence that the drug has antipaychotic activity. One of the questions that should interest you
is the possibility that it may have unique pronerties, but this hypothesis
is questioned by the two comparative studies.
I

was

Considering the extensive clinical studies, the EEG analysis
will
'after the fact'. In our recent work, we have ftcussed
on those compounds with interesting animal profiles and with limited
human data; for an EEC analysis is time consuming, and we have yet to
'prove' that this technique has merit. An analysis at this time would
add little to your body of data that would be helpful to your clinical
or your FDA position.
indeed be

Many

thanks for the opportunity to read this material.

Sinceeely yours,
Max

Fink, M.D.

Professor of Psychiatry

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