http://exhibits.library.stonybrook.edu/mfp/files/original/e738cce80d381f0851763e7f4ba75bb5.pdf 5f60d46f881c54759e93fcad7a4ef744 PDF Text Text ,___ .,. , ,.,-,..A.._r.: . n- - ., ._,a nvr.._.r~.,..,..v.;.x.—;~,7 r,l....y "new”... .,. . . w. ,1. ”pumac :»"'I:»‘ “mnxl—u w“ “T77“..wur-e wan-7‘ VIN-W“ ”Hm, ”“77. w__ ,. . m..., ,. . w. V ,. .17 “ave". Nauru-v. , -viwv.‘ .~ :- «>1 v—A was. January 24, 1972 unsw— ,me Nathan 8. Kline, M.D. Director of Research Rockland State Hospital Orangeburg, New York 10962 Dear Nate, As you know, I have been most interested in the development of narcotic antagonists as a treatment ior opiate dependence. After many years of effort, the model has been supported by clinical studies, and the qualities of an ideal antagonist have been defined. The National Institute of Mental Healhh, the SAODAP of the White House, NACC the State of New York, and the City of New York are all interested inof these programs. They are making research funds available, and their support has much to commend it. However, the principal agencies that have the facilities to produce the necessary formulations, the industrial laboratories, preoccupied by their prior committments, and some effort should bearemade to bring the needs of this program to the attention of the formulating chemists. With this in mind, I would ask that you consider approaching some of your foundation friends, with the idea a special award be established for the production of a successful that formulation with the following characteristics: specific narcotic antagonism, similar to naloxone; duration on single administration of 90 days, with antagonism to injected heroin, 25 mg/ch/2 minutes; tolerated by man ('safety'); and, without agonistic features. is the most likely starting substance now at hand, but other candidates may be l-cyclazocine, diprenorphine (M—SOSO), other specific antagonists now under study at Bristol, Geigy, or orother labs. Naloxone A single prize of $50,000 or $100,000 for 36 months, well publicized and supported by the authority of one of the leading found~ ations may serve this program handsomely. I hope you agree, and raise the question at the best levels. Sincerely yours, Max Fink, M.D. Professor of Psychigggy r//\ . s..,.,..,..7..,.. , ”r,“ e, vs, ,7...“ y... � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Kline, Nathan Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-026-1-108 Date A point or period of time associated with an event in the lifecycle of the resource 1972 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence