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                  <text>July 29.

1963

Dr. Neil Burch

Houstm State Psychiatric: Institute
1300 Moummd

Houston 25 , Texas
Dear Neil:

Ithmbeenmmakssinmmspm.butﬂmhawnotbmidlm
his letterisovom, so letmtakeeam immsexially.

m

9mm»

mny themes for the digital cards fran'mlm. The
,perfecmd «1 this material. In comaring cur analyses. the two
diffemd in mspmse to-mther manges to mm mm or mm not wanted
in the first derivative.” After finding this dismpanw, the prom was
nodal. Our analyses were than identical to
mdified t9 fit the
yours.
from John Stern and these wen
2. We obtained two digitized
mla'tad tad me writenmts
The
were
clearly
resulting spectra
malyzed.
which he pmvided.

l.

m

1

'

t

.

mm

'

Inbothmaseanalyses,webecaneomoormdabmtﬂumlim
problem. First, the 'mlane moord mquimd an "artificial" baseline (the
mean of first 1500 points). This was satisfactory because later samples

from this Muslim. In tha first Stem
samples did away above and below the
the
that
meow, hwaver,
As
had
we
no good solution, ow error was com-baseline
markedly.
initial
deymdifyingﬂmmwtopmvidecmmtamlms ofasmmy

showed no

as

5

doviatim
mistent fauna

baselines.

we

Such

data also yielded

mum information.

W.
asimwaveWmeEEG. mteringtm aim

we decided, that the least
Lately. in thinking this problem
from
baseline after recording
was
solution
mm
a
to analyze
artificial

onthe tapebybias

adjustments and recording 1313 ES wiﬁmt ovum» adjustmt.
baselim adeqmm.
this mien successfully and fomd a

m

r/

We

have done

�m».

Neil aura;

Our oquipmnt progress has been

3.

July 29.

~2-

rapid. Last week. the

1963

1710

systemwas installed and on I-‘tidaym were ablo to memo moan moord
on tape; digtiu at 320 and one 1312:. per second; analyze successive 24/2,
3, 5, 10 seomd epochs abwt 0. tom baseline. The muting 3mm, and

Guam with pcntotbnl, was very

300d.

In lockingat tho first derivatiw canton» famdthatwehadtoommh
noise. Our Offmr has ”choppers" at non ops (lodco more like: 60 cps) which

Thismk'a pmject-tooloanupmmsimlontapo.
Wand.
will not be in mtil mid-Manta and our plotter in Seytonber.

new EEG

Octoberwahopetobeopomtimalviaupo.

u. Behave
G.P.D.C."
with
a

report

"

modandmawmmm”hriodm1wisofﬁssm
and qwstims
few, as tho
intemst. (Mr

is straightforward; .
a.

Our

.By

mats

m

~

Themismstamntintminmtionoftmﬂwozyw

the goals of the analyses. For ammo, we we ootmmod as to rational:
for 2nd derivative Minamoto? How are those to be intorpmetod in View
of the "noise" of our amplifiers?
'

b. On page 10. the oonoem about the major index asymtry mounts
side to the baseline problem. If a "true" baselim were deter»
different
a
ntimd, amd if EEG waves were truly symetric, than the positive and negative
indioos wwld be equal. But, is there any masm to expect EEG signals to
be ammo? For mangle, the 3 ops spike and wave is asyzmetric. I
wmld suggest that the symtr-y of positive and negative counts be accepted
as a more of the wave characteristics; provided, a nm—arbitrazy way can
be famd to detemzine a reliable ("standard”) baseline.
0. We are concerned with the loss of informtim inherent in

filters

conversion; and mnning averages. Yaw method of obtaining
is desimod to reflect the fast activity
a
By filtering and averaging , the record is indeed
on a slower
clamor but a potential source of information is precluded. Why not keep
all the jitter and study it?
2nd

before

A-D

derivative (and lot deriVative)

War.

'

.

d.

Pmntlutioally. mm Pmst

and Nooll successful?

5. Enclosed is a paw writo~mt of cum analysis of your data, for 5
baselines. This sample ohm the prom permitting analyses of 5
«masses. and lot and 2nd derivative for up to 15 band widths. Epodx aim

mm

Wmmmm

andnmorofepochs oanalaobevariodatwill.
of the average froquoncy memo for the total sample. "Oounts" a
of
motor baselﬁmemqoa (or derivative cunts). Also, the oaloulotim of

mm

�Dr. Neil Burch

July 29,

«~3—

1963

the mam square of amplitude duviatims frm basalim at points when lit
(Mean sq.
derivative is zero gives an index of
m. s awn/mu).

mum

Weammwolemingupmrmpliﬁerayam.mdaasomasmtis
todaaamllstudyofvaxyingmtoﬁalmums indiffemnt

dam. :iplan
popula one.

in tbs
shéuld momma.
Wag
mtoemymtthismriam. mobsumtismmlm.hmom,
6. Thanks for

EEG

abatmat.“if~.’n‘xat

mmtammmmmmmmmmmmmtw.
m

Memzile. have ymr assistants had a damn at the, tapes?
Just mad a blmb that you will 30m have
tapes of the 3.3mm.
That project sounds like em awaiting application of yam data reductim
methods. I mld be pleasod to read any am
yam mp isms.

mm
-

Good

luck, and

my

best mgards.

Sinoamly ypum.

Max

Fink,

Director

Mf'dr
Emlosums

M.

D.

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