http://exhibits.library.stonybrook.edu/mfp/files/original/7618f4be2d528d7de71757a2c8b8c02e.pdf 48c3daf55f464a26d444d4e0cf62fc72 PDF Text Text n‘w‘ Va. r- - vm uw 4v m «wu— -- . ~ W “fl-WW" 1-: v. , rdm'wv'nvv"mwl'melwvva—H."IMF—VJ «.wi van :- Fabruary 22, 1972 Binaa, Ph.D. Director of Biological Research Hoffmann—La Roche, Inc. Nutley, flew Jersey 07110 Mr. L. R. Dear Len: I hava read the data ahaata on Lorfan and RD 6-6711 with interest. fiocuaaing on thair possible uaa in opiate dapandanca. The data on Ro 4~67ll ahows this to be similar to cyclazocine in structure, with similar side—effects on low oral dosage (0.5 mg) - sleepy, uncomfortable thoughts, “drunk",bhtt with vomiting also. Thasa effects reflect a nigh dagraa of agoniatic effects, canaidarably reducing our intaraat. data on Lorfan is more promising. It is a well defined antagonist, and a program dcaignad to extand its duration of action may be useful. It may be important, howavar, to clarify the commant in the packaga insert, regarding enhanced respiratory dapraasion with repeated doaaa. If varifiad, this will be a deterrant to further davolopaant. The Thanka for the opportunity to raviaw these data. Sincerely yours, Fink, fi.D. Professor of Psychiatry Max � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Hines, L.R. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-026-1-071 Date A point or period of time associated with an event in the lifecycle of the resource 1972 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence