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                  <text>February 22, 1972
Dr. E. Garden

Boston State Hospital
Boston, Maaaachusetts
Dear Dr. Gardos,

Enclosed is thc summary report 0! the EEG data analyses
of the high and low dose thlothixcnc studies completed recently. while there

technical difficulties, there was sufficient material to elicit
drug~EEG effects in the lang~tcrm treatment condition. Thu ahort~tcrm
cffccta were less clear, probably as a result of the small sample.
The decrease in mean frequency and in mean frequency
is consistent
variability measures with chronic thiothixcne administration
the
and
with
of
thiothlxcne,
thc
effects
of
ctudica
with our earlier
Pharmacol.
CAnn.
Rev.
earlier
publications
classification proposed in our

were some

9:2blv258, 1969).

h

I trust these data are
information, please call.
Hy

artful.

Should you wish any

further

best regards.
Sincerely yours,
Max

Fink, M.D.

Profcsaor of Psychiatry

cc:

J. 0.

Cole

�</text>
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