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                  <text>Howunbor 22, 1971

Dr. Donald

J. Jcnder

Department of Pharmacology
UCLA School of ﬁcdiciue
Los Angeles, California 90024
Dear Dr. Jender:

l was pleased to hour of your work and the techniques for
measuring low levels of acetylcholine, at the ﬁIHH meeting Friday.
Some years ago. in studying the electroshbck
process, the specificity
of anticnolinorgic drugs in reversing the ECT effect led me to poatulcte an elevation of acetylcholine as important to this effect. We
attempted some measures of CSF acetylcnoline, but our results were
unreliable. Recently, I approached the problem again, and sent some
fluids to Walter Essmau at Queen's College, ﬁew York, but he was cola
to measure other constituents, not acctylcholine.
Are the techniques yen describe ouitablc for CSF? is there
a way of stabilizing CSF~acetylcnolinc so that samples could be shipped?
Would your laboratory be interested in some samples of CSF in monkey.
and man, before and following ocizurca, to test the hypothesia
ccetylcholinc eiotation occurs and persists post~ECT7

any

I an enclosing a copy of my 1966 rcport,
relevant citations from your lnborctory.

and onould appreciate

Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

ﬂF:ig
Inc.

that

�</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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