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                  <text>September 13, 1971

Fritz Freyhan,
Editor,

M.D.

Comprehensive Peychiatry
153 West 11 Street
New York 10011
Dear

Fritz,
I

am

pleased to enclose a draft copy of a report of

our experiences with multiple monitored convulsive therapy,
Clinical Experiences with multiple Electrooonvulsive Treatments,
for your consideration for Comprehensive Psychiatry.
We have been able to assess the clinical efficacy
and the effects on memory of unilateral electrode placements,
and these studies led us to multiple treatments. We have been

surprised that the clinical results of multiple treatments
is not much greater than one seizure—- suggesting that the
biochemical changes after one seizure are near maximal, and
that some development, in time, is necessary for the full
development of the changes which are the basis for clinical
results. The finding is similar to the observations with
antidepressant medications.
I believe the report will interest our readers.
my

best regards.
Sincerely yours,
Fink, 24.1).
Professor of Psychiatry

Max

�</text>
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