http://exhibits.library.stonybrook.edu/mfp/files/original/627c03bbc9d9350e689bc18e1fefcc1e.pdf de74d893f567d02dd9a0cc156c51b13b PDF Text Text . 7“,. em...- W. ,,___ .vvwr _~_...__..... , "wave—”mp-.." WWW..- .. 94% 7/ Ron. Paul Rogers U.S. House of Representatives Washington, D.C. Dear Mr. Rogers, You may recall that this laboratory has been in the forefront of research in the use of narcotic antagonists (naloxone and cyclazocine) in the treatment and prophylaxis of opiate abuse; and that we organized the 1970 missing on this subject at the New York Academy of Medicine. I am writing to you at the suggestion of Professor Daniel Freedman of the University of Chicago, for I shared with him some of my doubts about our present national effort, and he recommended that I share these doubts with you. September 8 meeting on new approaches to the treatment of Opiate abuse organized by Drs. Jerome Jaffe and Robert Rees of the special office of the President. That meeting was a distinct disappointment, for the agenda was poorly prepared; the chairman was clearly ambivalent about the approaches and his interest in them; and the industry representatives were I attended the unwilling to alter their present committments, expressing the that there was little more that could be done. view Your committee is reviewing the President's reqiest for the development of a centralized approach to drug abuse. Such an office could have some merit, were the officers available with experience and knwledge to lead the national effort. The preliminary suggestions for the control of abuse in the military; their cavalier dismissal of suggestions for prophylaxis in the armed forces; and their apparent mishandling of the problem of narcotic antagonists makes me less than sanguine that the President's request will serve a useful purpose. It is true that the established agency for research, the National Institute of Hental Health, his lacked leadership, but the approach of a new office, with its own large staff and apparent inexperience cannot serve a useful public purpose. h 1. a “933i :5.1:“?og‘fifiztézr:3§1§°2%ngohhassle};ease,tags is also probable that naloxone is the drug of choice at present. It have a distinct naloxone and may that a combination of cyclasocine role in the present crisis in opiate dependence, particplarly in h �, .,. . . . .w.»,-:..-.Wvn-“r-p-V awn”.- .m «an—~71 .rr-wrm—V~fiv-nTv‘r -,.. . , a confined population, as in the treatment and for prophylaxis. . . -“T—vr.w..,..«. wrew...‘ military in .— W¢U< ‘rr—wr 5w mung—.7,“ Viet—Nai, both ~ u —- weww v for the meeting, I would conclude that Rude/DuPont are the efforts necessary to develop a long acting antagonist. While they ascribe their difficulties to the practical issues of raw materials, patents and limited staff, it is clear that they have other issues of greater concern to them, and their efforts in the area of drug abuse control are only the minimum required to assuage public demands. From not able to make It is also my opinion that the leadership in the President's office is also ambivalent, for they have not the experience with the combination of naloxone and cyclzocine, as well as having a public committment to methadone. For these reasons, among others, it may be useful for your Committee to consider the special commission approac -a commission dedicated to evaluate the possible uses and roles for the narcotic antagonists. Such a commission could: .2 m'rwrsmflv assure adequate supplies of naloxone for clinical in trials, part by alleviating the artificial quotas for the raw materials, principally thebaine; I coordinate, finance, and evaluate clinical and naloxone, particularly in prophylaxis ~ V-I' studies of cyclazocine in the military; invite contracts for the development of a long formulation of naloxone— (our experience with a acting silastic polymer formulation of naloxone makes us believe this approach to be feasible); support studies of antagonists; and, new provide an independent evaluation of methadone and the antagonists in treatment. rv-vwnm—t—w-u w-rnwmvr «aroma-w, m ( -.q. "v“ w. was»: v >'rvrvr»raraul Such a commission could include some of the industry representatives, called together at your request by the P.M.A., and some independent university members. The President's interest in drug abuse is commendable; the approach of developing a new office committeed to no definite goal makes it likely that it will be less efficient than a commission approach- even one designed as an integral part of the existing National Institute of Mental Health structure could be considered. I shall be in Europe until October 8, but should you or interested in discussing these views further, I your staff shall be available thereafter. be Sincerely yours, Fink, M.D. Professor of Psychiatry Max : � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. 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Title A name given to the resource Correspondence to: Rogers, Paul Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-025-7-463 Date A point or period of time associated with an event in the lifecycle of the resource 1971 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. 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