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                  <text>l9 September l97l
Arthur Sugerman, M.B.
Neuropsychiatric Institute
Princeton, New Jersey

A.
NJ

Dear Art,
has been a long time since we chatted about ECDEU
reading
affairs, or about stocks, and I was reminded of thisin in the
addicts
in
narcotic
on
recent
prazepam
report
your
Journal of Clinical Pharmacology. I found your report interesting

It

for it confirmed some of our observations with tybamate in a
similar group of subjects. We had tried to maintain patients on
tybamate during the post-drug withdrawal period, in the hOpe
thatbb tybamate would 'block' the craving for opiates and reduce
recidivism.

Unfortunately, our patients liked tybamate itself,
that
particularly when combined with alcohol. They reported
small doses of tybamate and small doses of alcohol acted

synergistically to give
can do

them a cheap

'high‘.

So far. there seems to be little more that we
for the Opiate dependent but reduce their symptoms

during withdrawal, or maintain them on methadone indefinitely.
the antagonists show these
still believe that our workwewith
have had difficulty in convincing
drugs to be most useful, but
the authorities that more efforts should be spent in this area.

we

My

best regards.

and

my

best wishes for

a happy new

Sincerely yours,
Max

Fink, M.D.

year.

�</text>
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