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                  <text>W___

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July 22,
Wan'mrvnnrawwr

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1971

Dear Turan,

I find the report for the Transcultural Symposium very
discussion, I would make two suggestions.

good. In the

data,

Prien

&amp;

Cole, in summarizing the high dose chlorpromazine
suggestions that dosage is a factor in the

make some

treatment of certain scizophrenics, particularly in relation to
age. I believe it would be helpful if their views were referred
to in the discussion.
w

JHW‘”

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in"""!""1‘1’7~'"‘7i

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W‘W5W-W7kfd

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WWWWWWTWWSEFW

During the past few years, there has been some discussion
about 'enzyme inductiog' as an aspect of the metabolism of
drugs which may affect the efficacy of drugs in some patients.
Prior experience with drugs permits the tissues to learn how
to metabolize or how to adapt to high tissue levels of the
most toxic agents. A good example is the development of tolerance

to opiate and hallucinogenic drugs. This, too, may be a useful
aspect of the discussion, particularly since it provides an
alternate explanation to the genetic hypothesis.

I have just returned from Athens, where I found the
study progressing very well. The initial case~finding phase
should be completed by the end of the summer, and I hope
to spend a few weeks in the actual examinations after the
WUrzburg meetings.
I trust you will enjoy the second half of your sabbatical,
and should you have the occasion to step in New York en route,
my home is open and your welcome is always assured. My best to
Ellen.

WWW"?

5;

Sincerely yours,

0'.

mm

"are

:
WWWM

Max

Fink, M.D.

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              <text>Correspondence to: Itil, Turan M.</text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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