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                  <text>August 20, 1971
Dr. Gardos
Boston State Hospital
Boston, Mass.
Dear Dr. Gerdos,

In response to your request, I have looked through the
on the high dose-low dose chlorpromazine

files for the report

study. The report was presented in 1967 and the data
sheet is enclosed. There is no summary report as I read the
paper form the slides.
EEG

'

Essentially, the records were collected by Dr. Denier
at Manhattan State Hospital and the tapes were analyzed in Missouri.
72 records were analyzed; and in the initill analyses, there were
no differences in the pre-records, indicating that the sampling

was

adequate.

records showed an increase in theta activity, and
fast frequencies with treatment, but there
use no significant difference in the EEG changes with low or high
The

a decrease in very
dosage.

earlier,

similar to thbse described
that the dosages were adequate. Most

The changes induced were

and indicated

interesting, the changes were already present with the low
dosage regimen and no important differences ensued with the
higher dosages. From these data, we could conclude that the
low dosages were sufficiently high (for these patients) to induce
the neccessary EEG effects, and that higher dosages had no
additional effects.

I tsust these

tapes as soon as they
in extracting

some

comments

arrive,

are useful.

we

will anilyze your

and perhaps we can be of some help

conclusions.

Sincerely yours,
Max

Fink, H.D.

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              <text>Correspondence to: Gardos, ?</text>
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              <text>1971 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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