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                  <text>May

13. 1971

Dr. William Tabor
A. H. Robins

1407 Cummings Road
Richmond, Virginia

Door 8111,

have recently completed our pilot EEG study of AHR~1118.
including experiments with single doses up to 350 ng, equivalent
to 4.5 ~ 5.0 ng/kg. We have summarised this data and I am enclosing
a capy for your information and files.
We

we have had difficulty in eliciting a
At these higher dosages, however, sous
changes are prominent and to confirm these, I have undertaken a
direct comparison, on a random assignment double~blind basis of
single doses of ARR 1118 vs. placebo. The dosage selected is
based on body weight, so that we will average 4.0 — 4.3 mg/kg.
The variation is based on the 50 mg size capsule available.

In these experiments,

consistent

EEG

pattern.

This study will be completed in early June at present rate
of examinations.

It

was good to see you

in Atlantic City.
Sincerely yours,
ﬂax Pink, H.D.

Professor of Psychiatry

Mszt

�</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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