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                  <text>.— w&gt;=vw-r-:Nn'r—"-vv e-w-T

May

20, 1971

Dr. Diana Johnson
Biomedical Information Scientist
University of California, Los Angeles
The Center for the Health Sciences
Los Angeles, California 90024
Dear Dr. Johnson:

Enclosed are the corrections you requested. Is there any
reason why you would not use the author~prepared abstract? I

would

prefer

it

to the enclosed version.

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

NF:kt

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.

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-

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-

7,7,

,

.

.

wy

ru— 1n»-

therapeutic effectiveness of unilateral electrode placement

and multiple
R.

;- -..

seizures in convulsive therapy has been studied

Dornbush, S.

Feldstein,

R. Abrams and

J.

by

M.

Fink,

Volavka (New York), with

the goal of reducing confusion and other side effects of such therapy
while maintaining

its beneficial action.

Seizures with unilateral

electrode placements results in less clouding of consciousness, earlier
waking, and less memory impairment than bitemporal placement.

bilateral

ECT

produces

its

Conventional

major impact on auditory verbal memory,

short~term memory is influenced

little

by

either unilateral

bilateral

and

Visual

bilateral

result in prolonged EEG
slowing with larger amplitudes over the left hemisphere, while unilateral
ECT produces higher amplitudes on the treated (right) side.
Bilateral
ECT is usually clinically more effective and faster.
There is a persistent
advantage to bilateral ECT for the first 4 treatments, but little difference
thereafter; an equivalent clinical effect was seen for 5 unilateral versus 4

ECT.

The EEG

seizures produced

bilateral treatments.

by

The use of

multiple

ECT

ECTS, 4

or

6

hyperoxygenation, appears to have approximately the same
as the same number of single treatments.
ECT

It

per day, under

effect

was concluded

that unilateral

is almost as efective as bilateral treatment, withoﬁttthe

memory

loss.

on memory

accompanying

Further study of multiple treatments are necessary.

has been thought that treatment effectiveness

but the persistence of slow

wave

is related to

activity appears to

memory

It
loss,

be more important.

V

7-;

�</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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