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                  <text>June 8, 1971
Mr. Vernon 3. Brooks

Section Editor, Neurobiology
‘Depsrtesnt of Physiology
New

York Medical College

New

York,

1 East 106th

New

Street

York 10029

Dear Vernon,

I have examined the two reports A142-l and A143-l, anticipating
an evaluation for the J.A.P. Unfortunately, both reports are focussed
on the evoked response, a technic with which I an familiar, but not
to a degree to be critical. I an returning these reports with the

suggestion that others more qualified than me rsvfevishethstistesles
would be Roy John, Charles Shsgass (Temple Univ.), Ed Domino (Michigan)
or Bert Rosner (Yale).

In A143, I read the section on scalp EEG. The samples presented
are interesting examples of the probable EEG differences between
cycloproprane and the group methoxyflurane, ethrsne and ether.
Indeed, the sample clearly shows a difference in spindling and in
dominant frequency among the three beta procedures. But the presenta—
tion lacks any quantification; there is no accommodation for differences
in the pre~drug EEG record; and there is no effort to relate the
differences in evoked potential to the differences in resting EEG
record. Even recognising the unique nature of this study, these
lacks (in 1971) show a deficiency which would require much compensation
from the remainder of the report to recommend its publication.

Incidentally, Table I seems misplaced.
I regret I cannot be of more specific help, but I cannot do
the journal or the authors justice. Thanks for thinking of me.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

nfzkt

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