http://exhibits.library.stonybrook.edu/mfp/files/original/557c1f00db9b7408bcf2134f42d8f843.pdf 282fe7036d2087da3c83bef7845dc890 PDF Text Text March 5, 1971 Dr. Jack Freund Robins Company 1407 Cummings Richmond, Virginia A. H. Dear Jack, have been very interested in the use of narcotic antagonists in treating opiate dependence, and since 1966 have carried out clinical studies with cyclazocine, naloxone, methadone, and £~alpha~acetylnethadol. Last fall I was asked to summarize our data, and in conclusion, I attempted a justification of the logic of the need for a long-acting formulation of an antagonist. We I believe that the methadone maintenance ”solution” to opiate dependence is politically expedient but not a long~term solution. I am concerned with the question of, "After a patient is on methadone, what next?” "Is he committed for life?" The antagonist model is theoretically elegant and clinically feasible. are committed to continuing our studies, have contracted with Food and Drug Research for some help; and would encourage others to experiment with other antagonists and long~acting formulations. wi We Incidentally. our experience with narcotic antagonists has led us to think of antagonists to other drugs of abuse, notably alcohol: and we have recently carried out some studies to determine the degree and duration of alcohol antagonism of propranolol. I trust the enclosed reprints are helpful. Sincerely yours, Fink, M.D. Professor of Psychiatry Max MF:kt � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Freund, Jack Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-025-3-243 Date A point or period of time associated with an event in the lifecycle of the resource 1971 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence