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                  <text>Murch 31, 1971

Dr. Michael A. Taylor
9309

murillo

Oakland, California
Dear Mickey,

it

The application is good, as
some additions.

for

far as

it

goes.

I

am

returning

Please review Pitts and McClure theory of chemistry of
lactate. ‘Thcre were some letters that were published
anxiety,
in response to our letter, that questioned the significance of a
lactate test, assigning a peripheral value to the symptoms. This
data should be referred to, and critiqued. Can you devise a test
of these criticiams?
(1)

and of

(2) You may wish to call Dr. Pitts in St. Louis (314 F0 lu4730):
and ask
tell him what you propose to do; ask him to he a consultant:
if there is any additional published, or unpublished data or hypotheses
he can make available to you.
i

If the separation of populations is successful, how can this
test be used in subsequent studies? In assessing treatment infailures,
depression,
for example? Does this test have any relevance to anxiety
(3)

or in schizophrenia?
human

(4)

What

are present tests for antianxiety—agents (animal screening,
Are there any limitations to present designs?

clinical)?

(5) I will ask Dick to describe equipment and facilities. You
should check budget, co~workers, comolcte biographical sketch, research

objectives.
(6)

Make up a

permit form to be signed by patients.

Separately, I will ask Dick and Voita Volavka to send you their
comments. Filing date is June 1.
Kirby is bloaaomigg nicely. Dick started this week. The resident
rotation is assured for July 1, for 4 NYMC residents at least, for 4 mos.
each. He will have to provide our own supervision. Staff seems adequate
in M.D.'s, S.W., psychologists and aides - short in nurses.
Have fun!
Max

HF:kt

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