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                  <text>February 8, 1971
Dr. Fred lagan
Upjohn Company
Kalamazoo, Michigan
Dear Bred,
At the APPA meetings this weekend
speak to Ronald Fieve about rubidium.

I

had the opportunity to
has an IND but the
restrictions for human trial are severe. To date he has increased d
dosages gradually to a dose (he could not recall) which seemed
He

insufficient to alter mood or behavior. He does have extensive
laboratory data, primarily blood, urine and EEG measurements.
These have been summarized in a report to the Aachiveb 06 Genenaz
Rbychlattg, but the report has not yet been accepted for publication.
In addition, he has animal toxicology
studies in progress.
He knows

(3 generations of mice)

of Plotman's public statement but diacounts the

evidence as inadequate. One basis for his interest is a review
of 19th centurj literature in which he noted many claims of therapeutic

benefit.

I was impressed with his enthusiasm and interest. He has a
good reputation, and while the evidence for psychoactivity is slim,
I would like to hear him discuss his work in public. If your interest
is sustained, I am sure he would be pleased to discuss his data.

It is

an

interesting problem.
Sincerely yours.
Pink, M.D.
Professor of Psychiatry

Me:

MF:kt

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              <text>Correspondence to: Kagan, Fred</text>
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              <text>mfp-05-00-025-2-152</text>
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              <text>1971 </text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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