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                  <text>arr v-.~.--um._.—-u.~ nw—Wn'mm.— 1.,,,_..,,.__,

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February 23, 1971
Dr. E. F. Domino
Department of Pharmacology

Medical Science Building
University of Michigan Medical School

M6322

The
Ann

Arbor, Michigan 48104

Dear Ed,
.m..—qrw&lt;w

to receive your review of the biochemical
studies in ECT. It may be obstinacy, but the
possibilities in
primary problem is acetylcholine, not the cholinesterases. That the
leech muscle is insensitive is a severe barrier, and these studies
will then have to wait the refinement of methods. The studies and
theories of epinephrine, norepinephrine and serotonin in psychiatry
received their heavensent thrust from the chemical description of
means of measurement, not from a theoretic model. Hepefully, the
same will follow when a new method for ACH is develoPed.
We

v-cwnv—r,

l-—

r

were pleased
CSF

Many

"Nu...

thanks for your frank discussion.

Sincerely yours,

mmvynpwy

-

V-mw'rwa

a

Fink, H.D.
Professor of Psychiatry

Max

In:

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Mszt

�</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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