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                  <text>v-r‘I-v‘

guru-WW.“

_

,

February 26, 1971
Dr. Frederick Gibbs
1427 N.

Chicago,

Astor St.

Illinois

60610

Dear Dr. Gibbs:
Your recent

EEG, I:
editorial (Clinicalw

127)

asserts that

"cannabis indica produces no marked or consistent changes in the
EEG" md ". .. the changes they [psychotomimetic drugs] produce in
the electrical activity of the cortex are of the same minor order
as are produced by tobacco“. It is difficult to see how you can
arrive at such sweeping conclusions, based on the data printed.
The report by Deliyannakis et a1. finds large effects of
cannabis, in a few subjects, with equipment of limited frequency
response. They make no effort at quantification and we have no
idea about the sample size, stability over time, artefact control,
Despite the limitations of equipment and technique,
filtering, etc.
they report large changes, albeit not in every subject.

In numerous studies of the EEG effects of heroin, LSD, major
changes have been observed and related to drug dosage, pro-existing
EEG and clinical effects
(for examples, see Ann. Rev. Pharmacology,
9:241—258,1969; Neuropharnacology, 9:539,1970). Such studies
show that large EEG Changes are common, drug and dose related, and

interestingly related to the behavior of the subject.

Considering the major strides made in quantitative EEG, it does
neither the science of EEG nor clinical practice a service to make such
sweeping assertions as "Let's face it, disordered psychic function,
either spontaneous or drug induced, commonly does not correlate with
major abnormalities in the waking electroencephalogram".

�Dr. Gibbs

~2-

February 26, 1971

Years ago we looked at the moon and saw a fairly flat surface
with a few ridges. With better tools. it became obiious that the
ridges, mountains and valleys were substantial. How substantial was
recently demonstrated by the astronauts limited ability to climb a
small ridge. The sruface EEG is not a homogeneous, insensitive flat
serface, but a sensitive, ever-changing reflection of mood, memory,
and

alertness.

use them.

Our

tools

Particularly,

do decode differences already, were we to
were we to look carefully, with the tools

of the 1970': not those of the 1940’s.

Sincerely yours,
Max

Fink, “.0.

Professor of Psychiatry

MF:kt

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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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