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                  <text>w

-

w... m. w.

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any

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my.

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January 25, 1971
Dr. Larry Stein

Wyeth Laboratories
P. O. Box 8299

Phi1ade1phia. Pennsy1vania 19101
Dear Larry,
I very much enjoyed your formu1ation

schi20phrenia.
experimentai study.

Hhi1e

it

fancifu1,

of

a

theory of

has the merit of some

of imipramine in schizophrenia
sti11 stands: there is no convincing
c1inica1 evidence that imipramine has antipsychotic properties.
He quotes your theory (1962) and Remmen et_gl;_- a poor c1inica1
On

re-reading Ban's

(pp. 278—279),

my comment

summary

vo1ume.

Enc1osed are some

reprints that

may

interest you. Po11ack's

disorganization of schizophrenia by imipramine; Kramer's
report
statement on combined imipramine - ch1orpromazine; our study of
ch1orpromaline;(0uprocyciidine) in depression; and a report by
Iti1 on high dose f1uphenazine. The more recent data on higher
dose f1uphenazine can be obtained direct1y from him.
on

.

,.

My

w.

regards.

w.

Sincere1y yours,

.

'ﬂ'v'ﬂ‘ﬂ“

:rart-vrm-A—w

Fink, M.D.
Professor of Psychiatry

Max

MF:kt

enc.

~e-vm---p.-wq.

Fwy—v—

“wavy—Wm...—

�</text>
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