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                  <text>January 25, l97l
Dr. N. Khazan
Mt. Sinai Hospital
New

York,

New York

Dear Dr. Khazan:

It

was a

pleasure to

visit

your laboratory. and to find so many

believe we may be able to assist you
quantification problems. and support the development
of an EEG quantification facility. He envision four steps:
(l) quantification of the data of your immediate projects.
using a variety of techniques for analysis;
problems of

common

in solving your

a

(2)

EEG

interest.

We

analysis of the data of specific projects, to provide
own data analysis unit;

basis for the development of your

(3) a review of the commercially available equipment
configurations and computer programs for data analysis for your needs;
and,

(4) an application for support. and the development of computer
programs for an analytic system for your laboratory.
For quantification using our IBM 1800 system. you will need an
FM tape recorder compatible with either our 7 channel (l/Z inch tape)
Aopex $9-300 or 4~channel (1/4 inch tape) Hewlett Packard 3960A. Copies
of specifications are attached: note the head configurations, tape speeds
and IRIG FM center frequencies and band widths (at various speeds) if you
1.

elect

a machine of another manufacturer. (He are not pleased with the
300 and suggest you investigate Sangamo or Hewlett Packard for a 7
channel recorder). You will also need an oscillator, similar to H0 202C.

SP

reviewed your usual method of data collection, the samples would
rats, continuous (or piecewise continuous) and the epoch
sizes, arbitrary. For period analysis, we are able to provide epochs of
any size, continuously analyzed, with a statistical output for the changes
after an event (drug administration) from the “resting” samples. If the
sample length is sdfficiently long, we can analyze the experiment at twice
As we

be subdural from l~5

the recording speed. The cost for AoD conversion, period analysis,
paper and card output is sou/hour of computing time.
.r'

war-:rr

“mmwm_w

..

”.115

r

statistics.

�Dr. Khazan

January 25, l97l

~2¢

If the recording and processing of the data are systematic, we are also
able to apply the appropriate multivariate statistics. Our present model is
based on linear regressions, and computer time using the 360/40 is calculated
at SlOOIhour with some pro~processing time at SlO/hour.
As a basis for future
to process the data in
optimal method. He are able to
analysis; to use power spectral

applications and for a defined project. you
variety of ways, to assure yourself of the
vary band widths and epoch sizes for period
density analysis; or to vary the multivariate
statistical approach. You should be aware that we now ore-filter our data.
between the tape and the A-D converter. The frequencies of interest to you
in the rat may differ from the frequencies which have customarily enjoyed
our interest, and you may wish to replicate the analysis of some samples
11.

may wish

one

without

filtering

and

a

at special filter settings.

Such experiments can be undertaken under the same conditions as

(I).

11!. Based on this experience, it should be possible to define your
needs and to canvass the equipment/software markets for the best configuration.
If done today. you should consider the lam loop (and our software) and the
DEC PDP«l2 (software in Philadelphia, St. Louis).
we once considered Control
Data and Scientific (Xerox) Data.Systems). There are additional manufacturers
that may be considered. Each should be canvassed for l97l~72 bids. we could
define your needs as we anticipate them or as they unfold in (I)(II), and obtain
the bids for you. It is important to consider the need for software support
and we can provide estimates for these costs. as well as deliver the programs.

(I!) and (III), we are prepared to assist
for support; and, as “consultants". to
participate in the defense of the application and in the establishment of
the program, including the training of the personnel.

IV. Based on the data of (I)
you in applying to funding sources

—

'

For the program outlined in (I), (II). and (ill) above, the direct
consulting rates are $300/day or $50/hour. A program rate for (l) and (II)
can be set at slSOOIouarter or a specific estimate for a project. For (1V),
the program charge is $4,600.

Rather than a piecemeal approach. you may prefer an annual consulting
and we estimate $6.000 based on our View of your needs.

It will

regards .

be a pleasure to have the opportunity

‘nvl

to assist you.

Our

fee.

best

Sincerely yours.

'wjr'ﬁ'v'c‘rrgtw'twmvlﬂ"

Fink, H.D.
Professor of Psychiatry

Max

w—n-m.

1‘
w

“ma-«“1

A

MFrkt

enc:

Brochure SP 300
Brochure HP 3960
EEG

Profile Analysis~Progress Report l970

Computer/EEG l967

Donald

Shapiro, D.Sc.
Professor of siestatistics
M.

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