http://exhibits.library.stonybrook.edu/mfp/files/original/dfc0d41511eeb22f65848bfd25085de9.pdf 0746b9a6c2a5c717a888cb8f53ca113e PDF Text Text "Mm-"- nx—an mm mu“..- . _I. 7. , _ , r. , .l . “www.mw, we“. ”aur.:g2;qusm; W"..-" uv' U, ~ rap-mum‘- November 12. 1970 mnmv-w—Vm mem 7 Dr. Allen Rankin Research Psychologist Psychopharmacology Research Branch National Institute of Mental Health 5454 Wisconsin Avenue Chevy Chase, Maryland 20015 Ya qr .FWy—v— Dear Allen, for the opportunity to read your report on depression subtypes. Taken together with Jonathan's heroic effort to be optimistic about the variety of new studies, your study indicates clearly that the present antidepressant drugs are an unsatisfactory answer to depressive illness. In part, this was presaged when, in reviewing the neuro-~ physiology of different psychoactive drug groups for the ACNP in 1968, I found four drug classes with four different neurophysiology patterns a reflection that no one treatment Thank you “var ., _...,.._..._,~. ,1... _ A _—.. — .-..-H.—rv,w-v—u— was satisfactory. . Vx-wn'rnwv~ .w .4 .. .0. a ,ivfl- warm-”v...“ ”Wm The reawakened interest in 1966-67 in unilateral electrode in multiple treatments in convulsive therapy led me to reopen my studies of ECT, and we have made some interesting observations. It is possible to effectively treat depressive or patients (of any age) within 3-5 days, without measurable made by possible is Such treatment rapid clinical memory loss. seizure of and rate oxygenation placement, changes in electrode induction. that ECT is the primary treatment for a It is apparent and that drug treatments may be most useful depressive state, regimens. and maintenance as adjuvants placement and - ECT comparisons are probably useful in the combinations delineating the relative dosages of each, andThis "radical" view Imipramine most suitable for each depression subtype. the initial startle reaction it, despite needing answers are two: questions specific has much to commend may excite. The it .w.-m,1.._... WNVWW w'o. maln>wwmm �w. -lwwww- ww “V. W,” ._....A.,. . ,~(v,'q ww _<,.. ,._—._ .t. ,W...‘,_ m ‘., “a “j .. Dr. Raskin November 12, 1970 -2— (1) For each of the psychotic, schizophrenia), is 3 ECT depressive subtypes, (neurotic, equally useful? (2) To what extent is a supplementary drug therapy necessary for each subtype; and which ”antidepressant" drug is most useful? A direct comparison of EC? and imipraminc should confirm the superiority of imipramine, as the Greenhlatt-Grosaer and Shepherd~NRC studies showed. (There are 5 other studies quoted by Klein and Davis showing ECT equal or better than imipramine.) Perhaps, the typology and predictor approach is more useful new. We ‘wwv—mr-wnu - y” Mandela have tried to confirm the Carney, the Robson and the predictor scores in our recent ECT study and were unsuccessful. is our latest report as sent to the Archives. I of the active ECT workers, and I look forward to discussing this work with you in Puerto Rico. Enclosed know many .-— Again, thanks for the preprint. .m. wry». Sincerely yours, ‘Wv-Fm-Mn Max .wrw-v «ow—pp mr’ - :WflvT'WTW’WJrV-‘WW_Z~UWMM~ r-u Fink gen. Professor of Psychiatry r," ‘(F :kt 811C 0 � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Raskin, Allen Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-024-9-485 Date A point or period of time associated with an event in the lifecycle of the resource 1970 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence